المؤلفون: Bergmann, Alan J., Breitenbach, Milena, Muñoz, Celine, Simon, Eszter, McCombie, Gregor, Biedermann, Maurus, Schönborn, Andreas, Vermeirssen, Etiënne L.M.

المصدر: ISSN:2214-2894 ; Food Packaging and Shelf Life.

مصطلحات موضوعية: Food contact materials (FCM), High-performance thin layer chromatography (HPTLC), Genotoxicity, Threshold of toxicological concern (TTC), Paperboard, Non-intentionally added substances (NIAS), info:eu-repo/classification/ddc/664

وصف الملف: application/pdf

Relation: https://doi.org/10.1016/j.fpsl.2023.101052; https://doi.org/10.21256/zhaw-27078; https://hdl.handle.net/11475/27078; https://digitalcollection.zhaw.ch/handle/11475/27078

الاتاحة: https://hdl.handle.net/11475/27078
https://doi.org/10.1016/j.fpsl.2023.101052
https://doi.org/10.21256/zhaw-27078
https://digitalcollection.zhaw.ch/handle/11475/27078

المؤلفون: Kelly A. Magurany, J. Caroline English, Kevin D. Cox

مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Inorganic Chemistry, Space Science, Environmental Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Threshold of toxicological concern (TTC), drinking water, risk assessment, qualitative, uncertainty factors, comparative point of departure (cPOD), NSF/ANSI/CAN 600

Relation: https://figshare.com/articles/journal_contribution/Application_of_the_threshold_of_toxicological_concern_TTC_in_the_evaluation_of_drinking_water_contact_chemicals/24675335

الاتاحة: https://doi.org/10.6084/m9.figshare.24675335.v1
https://figshare.com/articles/journal_contribution/Application_of_the_threshold_of_toxicological_concern_TTC_in_the_evaluation_of_drinking_water_contact_chemicals/24675335

المؤلفون: Chantel I. Nicolas, Matthew W. Linakis, Melyssa S. Minto, Kamel Mansouri, Rebecca A. Clewell, Miyoung Yoon, John F. Wambaugh, Grace Patlewicz, Patrick D. McMullen, Melvin E. Andersen, Harvey J. Clewell III

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: Threshold of toxicological concern (TTC), computational toxicology, in silico, high-throughput risk prioritization, margin of exposure (MoE), Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.980747/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/c77f706ac85c49c3bc5d018511b024a1

المؤلفون: Laroche C, Aggarwal M, Bender H, Benndorf P, Birk B, Crozier J, Dal Negro G, De Gaetano F, Desaintes C, Gardner I, Hubesch B, Irizar A, John D, Kumar V, Lostia A, Manou I, Monshouwer M, Müller BP, Paini A, Reid K, Rowan T, Sachana M, Schutte K, Stirling C, Taalman R, van Aerts L, Weissenhorn R, Sauer UG

المساهمون: Universitat Rovira i Virgili

المصدر: Regulatory Toxicology And Pharmacology ; 10.1016/j.yrtph.2018.08.006 ; Regulatory Toxicology And Pharmacology. 995-21

مصطلحات موضوعية: Medicine (Miscellaneous),Medicine, Legal,Pharmacology & Pharmacy,Toxicology, Weight-of-evidence (woe), threshold of toxicological concern (ttc), physiologically-based kinetic (pbk) modelling, metabolism, integrated approach for testing and assessment (iata), in vitro to in vivo extrapolation (ivive), hazard and risk assessment, excretion (adme), distribution, and elimination, absorption, Toxicology, Saúde coletiva, Química, Pharmacology & pharmacy, Odontología, Medicine, legal, Medicine (miscellaneous), Medicina ii, Medicina i, Interdisciplinar, Farmacia, Ciências biológicas ii, Ciências biológicas i, Ciências ambientais, Ciência de alimentos, Biotecnología

Relation: http://hdl.handle.net/20.500.11797/imarina5132993

الاتاحة: https://hdl.handle.net/20.500.11797/imarina5132993

المؤلفون: Chie FUKUI, Kentaro TAKAHARA, Toshifumi MIYAWAKI, Yuji HAISHIMA, Yuki MORISHIT, Yusuke NOMURA, 宮脇 俊文, 森下 裕貴, 福井 千恵, 蓜島 由二, 野村 祐介, 高原 健太郎

المصدر: レギュラトリーサイエンス学会誌 / Regulatory Science of Medical Products. 2020, 10(2):69

المؤلفون: Kotapati Nalini1*2, Palnati Narmada1, Adibhatla Kali Satya Bhujanga Rao1, Gopal Vaidyanathan1, Sanasi Paul Douglas2

مصطلحات موضوعية: Potential Genotoxic Impurities, Minodronic Acid, LC-MS, Single Ion Monitoring (SIM), Threshold of Toxicological Concern (TTC), Genotoxic Impurity (GTI), Potential Genotoxic Impurity (PGI's)

Relation: https://zenodo.org/communities/iajpr; https://doi.org/10.5281/zenodo.2526718; https://doi.org/10.5281/zenodo.2526719; oai:zenodo.org:2526719

الاتاحة: https://doi.org/10.5281/zenodo.2526719

المؤلفون: Kerecman Myers, Dayna, Goldberg, Alan M., Poth, Albrecht, Wolf, Michael F., Carraway, Joseph, McKim, James M., Coleman, Kelly P, Hutchinson, Richard, Brown, Ronald, Krug, Harald F, Bahinski, Anthony, Hartung, Thomas

المصدر: Alternatives to Animal Experimentation : ALTEX. 2017, 34(4), pp. 479-500. ISSN 0946-7785. eISSN 1868-8551. Available under: doi:10.14573/altex.1608081

مصطلحات موضوعية: in vitro testing, refinement, skin sensitization, threshold of toxicological concern (TTC), nanotoxicology, ddc:570

وصف الملف: application/pdf

Relation: http://nbn-resolving.de/urn:nbn:de:bsz:352-2--1lvvo1jz1o7nv9; http://dx.doi.org/10.14573/altex.1608081; 496054937

الاتاحة: http://nbn-resolving.de/urn:nbn:de:bsz:352-2--1lvvo1jz1o7nv9
https://doi.org/10.14573/altex.1608081

المؤلفون: Вачкова-Петрова, Р.

المصدر: Социална медицина; Vol 24, No 1 (2016); 14-17 ; Social Medicine; Vol 24, No 1 (2016); 14-17 ; 2603-3739 ; 1310-1757

مصطلحات موضوعية: Threshold of toxicological concern (TTC) Threshold of Regulation (TOR), dietary exposure, decision three

وصف الملف: application/pdf

Relation: https://journals.mu-varna.bg/index.php/sm/article/view/1711/1667; https://journals.mu-varna.bg/index.php/sm/article/view/1711

الاتاحة: https://journals.mu-varna.bg/index.php/sm/article/view/1711
https://doi.org/10.14748/sm.v1i1.1711

المؤلفون: Chantel I. Nicolas, Matthew W. Linakis, Melyssa S. Minto, Kamel Mansouri, Rebecca A. Clewell, Miyoung Yoon, John F. Wambaugh, Grace Patlewicz, Patrick D. McMullen, Melvin E. Andersen, Harvey J. Clewell III

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, Threshold of toxicological concern (TTC), computational toxicology, in silico, high-throughput risk prioritization, margin of exposure (MoE)

Relation: https://figshare.com/articles/dataset/DataSheet1_Estimating_provisional_margins_of_exposure_for_data-poor_chemicals_using_high-throughput_computational_methods_ZIP/21292404

الاتاحة: https://doi.org/10.3389/fphar.2022.980747.s001
https://figshare.com/articles/dataset/DataSheet1_Estimating_provisional_margins_of_exposure_for_data-poor_chemicals_using_high-throughput_computational_methods_ZIP/21292404

المؤلفون: Mbv, Narayana, Kb, Chandrasekhar, Bm, Rao

المساهمون: Analytical Research, Matrix Laboratories limited, Hyderabad, India

المصدر: ISSN: 1948-593X ; Journal of Bioanalysis & Biomedicine ; https://hal.science/hal-04019445 ; Journal of Bioanalysis & Biomedicine, 2012, 04 (6), pp.104-107. ⟨10.4172/1948-593x.1000072⟩.

مصطلحات موضوعية: Genotoxic impurity Liquid Chromatography Mass Spectrometry (LCMS) 4-Chloro-1-Hydroxy Butane sulfonic acid sodium salt ppm (parts per million) Sumatriptan Threshold of Toxicological Concern (TTC), Genotoxic impurity, Liquid Chromatography Mass Spectrometry (LCMS), 4-Chloro-1-Hydroxy Butane sulfonic acid sodium salt, ppm (parts per million), Sumatriptan, Threshold of Toxicological Concern (TTC), [SDV]Life Sciences [q-bio]

Relation: hal-04019445; https://hal.science/hal-04019445; https://hal.science/hal-04019445/document; https://hal.science/hal-04019445/file/quantification-of-genotoxic-impurity-4-chloro-1-hydroxy-butane-sulfonic-acid-sodium-salt-by-lcmsms-in-sumatriptan-succinate-1948-593X.1000072.pdf

الاتاحة: https://hal.science/hal-04019445
https://hal.science/hal-04019445/document
https://hal.science/hal-04019445/file/quantification-of-genotoxic-impurity-4-chloro-1-hydroxy-butane-sulfonic-acid-sodium-salt-by-lcmsms-in-sumatriptan-succinate-1948-593X.1000072.pdf
https://doi.org/10.4172/1948-593x.1000072

المؤلفون: EFSA Panel on Plant Protection Products and their Residues

المصدر: EFSA Journal, Vol 10, Iss 7 (2012)

مصطلحات موضوعية: Pesticide metabolites, dietary exposure, endocrine disruptor, Quantitative Structure Activity Relationship, (Q)SAR, read-across, stereoisomer, Threshold of Toxicological Concern (TTC), Nutrition. Foods and food supply, TX341-641, Chemical technology, TP1-1185

وصف الملف: electronic resource

Relation: http://www.efsa.europa.eu/en/efsajournal/doc/2799.pdf; https://doaj.org/toc/1831-4732

URL الوصول: https://doaj.org/article/8258b550176e4b89bfcb248c09cbb48d

المؤلفون: Mark D. Nelms, Grace Patlewicz

مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, threshold of toxicological concern (TTC), inhalation, Cramer, Kroes, Verhaar, OASIS Aquatic MOA

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Derivation_of_New_Threshold_of_Toxicological_Concern_Values_for_Exposure_via_Inhalation_for_Environmentally-Relevant_Chemicals_xlsx/13101917

الاتاحة: https://doi.org/10.3389/ftox.2020.580347.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Derivation_of_New_Threshold_of_Toxicological_Concern_Values_for_Exposure_via_Inhalation_for_Environmentally-Relevant_Chemicals_xlsx/13101917

المؤلفون: Mark D. Nelms, Grace Patlewicz

مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, threshold of toxicological concern (TTC), inhalation, Cramer, Kroes, Verhaar, OASIS Aquatic MOA

Relation: https://figshare.com/articles/figure/Image_5_Derivation_of_New_Threshold_of_Toxicological_Concern_Values_for_Exposure_via_Inhalation_for_Environmentally-Relevant_Chemicals_jpg/13101959

الاتاحة: https://doi.org/10.3389/ftox.2020.580347.s015
https://figshare.com/articles/figure/Image_5_Derivation_of_New_Threshold_of_Toxicological_Concern_Values_for_Exposure_via_Inhalation_for_Environmentally-Relevant_Chemicals_jpg/13101959

المؤلفون: Mark D. Nelms, Grace Patlewicz

مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, threshold of toxicological concern (TTC), inhalation, Cramer, Kroes, Verhaar, OASIS Aquatic MOA

Relation: https://figshare.com/articles/dataset/Table_1_Derivation_of_New_Threshold_of_Toxicological_Concern_Values_for_Exposure_via_Inhalation_for_Environmentally-Relevant_Chemicals_docx/13101974

الاتاحة: https://doi.org/10.3389/ftox.2020.580347.s020
https://figshare.com/articles/dataset/Table_1_Derivation_of_New_Threshold_of_Toxicological_Concern_Values_for_Exposure_via_Inhalation_for_Environmentally-Relevant_Chemicals_docx/13101974

المؤلفون: Fumitake Fukutomi, Yoichi Konishi, 小西 陽一, 福冨 文武

المصدر: 日本食品化学学会誌 / Japanese Journal of Food Chemistry and Safety. 2008, 15(2):51

مصطلحات موضوعية: Threshold of Toxicological Concern TTC, computational toxicology, in silico, high-throughput risk prioritization, margin of exposure

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586287; https://dx.doi.org/10.3389/fphar.2022.980747

الاتاحة: https://dx.doi.org/10.23719/1528376
https://catalog.data.gov/dataset/4a0a0f77-031e-4962-b748-865ba3afadd2

المؤلفون: E Rorije, A Peijnenburg, J Cotterill, I Eberini, J van Klaveren

المساهمون: E. Rorije, A. Peijnenburg, J. Cotterill, I. Eberini, J. van Klaveren

مصطلحات موضوعية: Mixture toxicity, (Quantitative) Structure-Activity Relationships ((Q)SARs), Threshold of Toxicological Concern (TTC), Read Across, Hepatotoxicity, Molecular docking simulation, Settore BIO/10 - Biochimica

Relation: Annual Congress of EUSAAT; http://hdl.handle.net/2434/526768

الاتاحة: http://hdl.handle.net/2434/526768

المؤلفون: Helga Rothe, Alessandro Chiodini, Mark T. D. Cronin, Clive Roper, Nancy A. Monteiro-Riviere, Joost Westerhout, Richard H. Guy, Jacqueline Whyte, Faith M. Williams, Chihae Yang, Gordon Barrett, James R. Plautz

المصدر: Regulatory toxicology and pharmacology : RTP. 76

مصطلحات موضوعية: No-observed-adverse-effect level, Skin Absorption, Cosmetic chemical, Decision tree, Administration, Oral, Biological Availability, Cosmetics, 010501 environmental sciences, Toxicology, Administration, Cutaneous, 030226 pharmacology & pharmacy, 01 natural sciences, Models, Biological, Risk Assessment, Intestinal absorption, Threshold of Toxicological Concern (TTC), Chemical exposure, 03 medical and health sciences, 0302 clinical medicine, Statistics, Toxicity Tests, Medicine, Animals, Humans, 0105 earth and related environmental sciences, Skin, Flux, No-Observed-Adverse-Effect Level, Toxicity data, Systemic bioavailability, Dose-Response Relationship, Drug, business.industry, Skin exposure, Decision Trees, General Medicine, Intestinal Absorption, Consumer Product Safety, Skin penetration, Dermal, business, Risk assessment, Prediction, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266eda6dcb6cf569affcf618a2a47119
https://pubmed.ncbi.nlm.nih.gov/26825378

المؤلفون: Oberdoerster, Jan

المصدر: Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

مصطلحات موضوعية: Threshold of Toxicological Concern (TTC), extractable/leachable, risk assessment, hazard assessment, Materials Science and Engineering

وصف الملف: application/pdf

Relation: https://dc.engconfintl.org/biopoly/35; https://dc.engconfintl.org/cgi/viewcontent.cgi?article=1034&context=biopoly

الاتاحة: https://dc.engconfintl.org/biopoly/35
https://dc.engconfintl.org/cgi/viewcontent.cgi?article=1034&context=biopoly

المؤلفون: Anzali, Soheila, Berthold, Michael R., Fioravanzo, Elena, Neagu, Daniel, Pery, Alexandre R.R., Worth, Andrew P., Yang, Chihae, Cronin, Mark, Richarz, Andrea-Nicole

المساهمون: Institut National de l'Environnement Industriel et des Risques (INERIS)

المصدر: IFSCC Magazine ; https://hal-ineris.archives-ouvertes.fr/ineris-00963409 ; IFSCC Magazine, 2012, 15 (4), pp.249-255

مصطلحات موضوعية: TOXICITY, COMPUTATIONAL MODELS, RISK ASSESSMENT, THRESHOLD OF TOXICOLOGICAL CONCERN (TTC), COSMETIC INGREDIENTS LNVENTORY, [SDV.TOX]Life Sciences [q-bio]/Toxicology, [SDE]Environmental Sciences

Relation: ineris-00963409; https://hal-ineris.archives-ouvertes.fr/ineris-00963409; INERIS: EN-2012-465

الاتاحة: https://hal-ineris.archives-ouvertes.fr/ineris-00963409