المؤلفون: Jeremy S. Francis, PhD, Ireneusz Wojtas, PhD, Vladimir Markov, MD, Steven J. Gray, PhD, Thomas J. McCown, PhD, R. Jude Samulski, PhD, Larissa T. Bilaniuk, MD, Dah-Jyuu Wang, PhD, Darryl C. De Vivo, MD, Christopher G. Janson, MD, Paola Leone, PhD

المصدر: Neurobiology of Disease, Vol 96, Iss , Pp 323-334 (2016)

مصطلحات موضوعية: N-acetylaspartate, Aspartoacylase, Canavan disease, Myelination, Energy, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996116302340; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/36bbbc38714a4910a6a154ba0ec668da

المؤلفون: Marciano Figueroa, Jeremy S. Francis, Steve Gray, Vladimir Markov, Thomas J. McCown, Paola Leone, R. Jude Samulski, Irenuez D. Wojtas

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 520-534 (2021)
Molecular Therapy. Methods & Clinical Development

مصطلحات موضوعية: 0301 basic medicine, Biodistribution, lcsh:QH426-470, viruses, 03 medical and health sciences, Transduction (genetics), Route of administration, 0302 clinical medicine, Genetics, medicine, Vector (molecular biology), lcsh:QH573-671, Molecular Biology, Tropism, business.industry, lcsh:Cytology, medicine.disease, Virology, Canavan disease, Oligodendrocyte, Aspartoacylase, lcsh:Genetics, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Molecular Medicine, Original Article, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0562ee554555fe3f3a5ff79ef249e4
http://www.sciencedirect.com/science/article/pii/S2329050121000097

المؤلفون: Thomas J. McCown, Sara K. Powell, R. Jude Samulski

المصدر: Mol Ther

مصطلحات موضوعية: Male, viruses, Transgene, Genetic Vectors, Gene Expression, Biology, Rats, Sprague-Dawley, 03 medical and health sciences, Transduction (genetics), Capsid, 0302 clinical medicine, Transduction, Genetic, Drug Discovery, Gene expression, Genetics, Animals, Humans, Transgenes, Promoter Regions, Genetic, Enhancer, Molecular Biology, Gene, 030304 developmental biology, Neurons, Pharmacology, 0303 health sciences, HEK 293 cells, Promoter, Genetic Therapy, Dependovirus, Corpus Striatum, Rats, Cell biology, HEK293 Cells, 030220 oncology & carcinogenesis, Molecular Medicine, Capsid Proteins, Original Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b972128e5b67ebf48d5f344da7db63
https://doi.org/10.1016/j.ymthe.2020.03.007

المؤلفون: Milton H. Werner, Jeffrey H. Kordower, Deniz Kirik, Erwan Bezard, Angela A. Rutkowski, Benjamin M. Hiller, David J. Marmion, Steven J. Gray, Thomas J. McCown, Diptaman Chatterjee

المصدر: Neurobiology of Disease, Vol 148, Iss, Pp 105184-(2021)

مصطلحات موضوعية: 0301 basic medicine, Cytoplasmic inclusion, Genetic Vectors, Biology, lcsh:RC321-571, Stereotaxic Techniques, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Atrophy, Nonhuman primate, Models, mental disorders, medicine, Animals, Humans, Alpha synuclein, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Alpha-synuclein, Neurons, Cerebellar ataxia, Parkinsonism, Putamen, Neurodegeneration, Multiple system atrophy, Dependovirus, medicine.disease, Astrogliosis, Rats, nervous system diseases, Neostriatum, Disease Models, Animal, Macaca fascicularis, Oligodendroglia, 030104 developmental biology, Neurology, chemistry, nervous system, alpha-Synuclein, medicine.symptom, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffcdf05a1ad4021b2eb7a585952b25c
http://www.sciencedirect.com/science/article/pii/S0969996120304599

المؤلفون: Rebecca P. Haberman, Thomas J. Mccown, Jude Samulski, J. Virol, Richard Jude Samulski

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/74/18/8732.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.324.6189; http://jvi.asm.org/content/74/18/8732.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.324.6189
http://jvi.asm.org/content/74/18/8732.full.pdf

المؤلفون: Larissa T. Bilaniuk, Paola Leone, Thomas J. McCown, Darryl C. De Vivo, Steven J. Gray, Vladimir Markov, Dah Jyuu Wang, Ireneusz D. Wojtas, Christopher G. Janson, Jeremy S. Francis, R. Jude Samulski

المصدر: Neurobiology of Disease, Vol 96, Iss, Pp 323-334 (2016)

مصطلحات موضوعية: Male, 0301 basic medicine, Genetic enhancement, Autophagy-Related Proteins, Mice, Myelin, Myelination, 0302 clinical medicine, N-acetylaspartate, Basic Helix-Loop-Helix Transcription Factors, Child, Myelin Sheath, Movement Disorders, Energy, Intracellular Signaling Peptides and Proteins, Brain, Neurodegenerative Diseases, Dependovirus, Oligodendroglia, medicine.anatomical_structure, Neurology, Child, Preschool, Disease Progression, Female, Green Fluorescent Proteins, Mice, Transgenic, Biology, Article, Amidohydrolases, lcsh:RC321-571, 03 medical and health sciences, medicine, Animals, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Aspartic Acid, Aspartoacylase, Leukodystrophy, Infant, Myelin Basic Protein, Canavan disease, medicine.disease, Oligodendrocyte, HEK293 Cells, 030104 developmental biology, Gene Expression Regulation, nervous system, Energy Metabolism, Motor Deficit, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10226c8206c1ea716a4cf2195a7d8c9e
http://www.sciencedirect.com/science/article/pii/S0969996116302340

المؤلفون: Christina L. Parker, Steven J. Gray, G Matsushima, Thomas J. McCown, Sara K. Powell, N Khan, Richard Jude Samulski

المصدر: Gene Therapy. 23:807-814

مصطلحات موضوعية: Male, 0301 basic medicine, viruses, Genetic Vectors, Clone (cell biology), Gene delivery, Biology, Article, Virus, Viral vector, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Gene expression, Genetics, medicine, Animals, Humans, Promoter Regions, Genetic, Molecular Biology, Tropism, Gene Transfer Techniques, Genetic Therapy, Dependovirus, Virology, Oligodendrocyte, Rats, Mice, Inbred C57BL, Oligodendroglia, HEK293 Cells, Infusions, Intraventricular, 030104 developmental biology, medicine.anatomical_structure, Capsid, Injections, Intravenous, Molecular Medicine, Capsid Proteins, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a959ce5f26dfb6ed776908ed6f210c
https://doi.org/10.1038/gt.2016.62

المؤلفون: Teresa Ravizza, Annamaria Vezzani, Thomas J Mccown, Rosaria Pascente, Albert J. Becker, Karen M.J. van Loo, Chrysavgi Kostoula, Susanne Schoch

المصدر: Molecular Neurobiology.

مصطلحات موضوعية: Male, 0301 basic medicine, Green Fluorescent Proteins, Interleukin-1beta, Neuroscience (miscellaneous), Context (language use), Hippocampus, Epileptogenesis, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Imaging, Three-Dimensional, Status Epilepticus, 0302 clinical medicine, Genes, Reporter, In vivo, Glial Fibrillary Acidic Protein, medicine, Animals, Humans, Bioluminescence imaging, Luciferases, Promoter Regions, Genetic, Neuroinflammation, Kainic Acid, Glial fibrillary acidic protein, biology, Mice, Inbred C57BL, RAW 264.7 Cells, 030104 developmental biology, medicine.anatomical_structure, Neurology, Astrocytes, Luminescent Measurements, biology.protein, Neuroscience, 030217 neurology & neurosurgery, Preclinical imaging, Astrocyte

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db844e83f4a6ff6e2f364d61dae2877
https://doi.org/10.1007/s12035-017-0660-x

المؤلفون: R. Jude Samulski, Marc S. Weinberg, Thomas J. McCown

المصدر: Neuropharmacology

مصطلحات موضوعية: viruses, Transgene, Genetic enhancement, Genetic Vectors, Central nervous system, Gene Expression, Disease, Biology, medicine.disease_cause, Article, Virus, Viral vector, Cellular and Molecular Neuroscience, Transduction (genetics), medicine, Animals, Humans, Transgenes, Adeno-associated virus, Injections, Intraventricular, Pharmacology, Genetic Therapy, Dependovirus, medicine.anatomical_structure, Immunology, Nervous System Diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04504cb67d222b4453245028ce250aa
https://doi.org/10.1016/j.neuropharm.2012.03.004

المؤلفون: S Nagabhushan Kalburgi, Thomas J. McCown, R. Jude Samulski, Steven J. Gray

المصدر: Gene therapy

مصطلحات موضوعية: viruses, Transgene, Genetic Vectors, Central nervous system, non-human primate, Biology, Gene delivery, Cisterna magna, Article, cerebrospinal fluid, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Transduction (genetics), 0302 clinical medicine, Cerebrospinal fluid, Transduction, Genetic, Genetics, medicine, Animals, Tissue Distribution, Molecular Biology, Injections, Spinal, 030304 developmental biology, Motor Neurons, Mice, Inbred BALB C, 0303 health sciences, Brain, AAV, Gene Therapy, Dependovirus, Motor neuron, Spinal cord, Antibodies, Neutralizing, Virology, Rats, Macaca fascicularis, medicine.anatomical_structure, Spinal Cord, Immunology, Blood Vessels, Molecular Medicine, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f318eb282d9447700b36ebb448fb648
https://doi.org/10.1038/gt.2012.101

المؤلفون: R. Jude Samulski, Stacey B. Foti, Bonnie Taylor-Blake, Steven J. Gray, Mark J. Zylka, Thomas J. McCown, Joel W. Schwartz, Jennifer Coleman, Lavanya Bachaboina, Michael D. Ehlers

المصدر: Human Gene Therapy. 22:1143-1153

مصطلحات موضوعية: Central Nervous System, Gene Expression Regulation, Viral, Methyl-CpG-Binding Protein 2, Genetic Vectors, Biology, medicine.disease_cause, Rats, Sprague-Dawley, Mice, Transduction (genetics), Transduction, Genetic, Peripheral Nervous System, Gene expression, Methods, Genetics, medicine, Animals, Humans, Gene silencing, Gene Silencing, Promoter Regions, Genetic, Molecular Biology, Adeno-associated virus, Neurons, Regulation of gene expression, Mice, Inbred BALB C, Gene Expression Profiling, HEK 293 cells, Promoter, Dependovirus, Molecular biology, Actins, Rats, Gene expression profiling, Enhancer Elements, Genetic, HEK293 Cells, Organ Specificity, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130bd5c34c0668c2f14fbfe0c5f485ab
https://doi.org/10.1089/hum.2010.245

المؤلفون: Dayna M. Hayes, Inmaculada Cubero, Todd E. Thiele, Montserrat Navarro, George R. Breese, Jon R. Fee, Thomas J. McCown, Jose Manuel Lerma-Cabrera, Darin J. Knapp, Francisca Carvajal

المصدر: Addiction Biology. 17:338-350

مصطلحات موضوعية: Pharmacology, Agonist, medicine.medical_specialty, medicine.drug_class, Medicine (miscellaneous), Striatum, Nucleus accumbens, Biology, Neuropeptide Y receptor, humanities, Psychiatry and Mental health, Endocrinology, medicine.anatomical_structure, Internal medicine, mental disorders, medicine, Signal transduction, Receptor, Protein kinase A, Sensitization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::948e3167b33d5c9fa7af04e1387d33da
https://doi.org/10.1111/j.1369-1600.2011.00336.x

المؤلفون: Steven J, Gray, Bonita L, Blake, Hugh E, Criswell, Sarah C, Nicolson, R Jude, Samulski, Thomas J, McCown, Wuping, Li

المصدر: Molecular Therapy. 18:570-578

مصطلحات موضوعية: Cell Survival, Green Fluorescent Proteins, Biology, Blood–brain barrier, medicine.disease_cause, Virus, Cell Line, Green fluorescent protein, Mice, Transduction (genetics), Capsid, Seizures, Piriform cortex, Drug Discovery, Genetics, medicine, Animals, Humans, Molecular Biology, Adeno-associated virus, Neurons, Pharmacology, Mice, Inbred BALB C, Kainic Acid, Microscopy, Confocal, Original Articles, DNA, Genetic Therapy, Dependovirus, Immunohistochemistry, Corrigenda, Virology, Rats, DNA shuffling, medicine.anatomical_structure, nervous system, Blood-Brain Barrier, Molecular Medicine, Female, Directed Molecular Evolution

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ee72d786761ad4f52c7ae018699657
https://doi.org/10.1038/mt.2009.292

المؤلفون: Ming Teng Koh, Michela Gallagher, Rebecca P. Haberman, Thomas J. McCown, Stacey B. Foti

المصدر: Neuropsychopharmacology. 35:1016-1025

مصطلحات موضوعية: Male, Aging, Levetiracetam, Hippocampus, Water maze, Hippocampal formation, Spatial memory, Transduction, Genetic, Memory improvement, medicine, Animals, Memory impairment, Neuropeptide Y, Rats, Long-Evans, Maze Learning, Pharmacology, Radial arm maze, Dose-Response Relationship, Drug, Valproic Acid, Cognitive disorder, Age Factors, medicine.disease, CA3 Region, Hippocampal, Piracetam, Peptide Fragments, Rats, Disease Models, Animal, Drug Combinations, Psychiatry and Mental health, Space Perception, Original Article, Anticonvulsants, Cognition Disorders, Psychology, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e3cf974fb5f5ae33738a6817a0950d
https://doi.org/10.1038/npp.2009.207

المؤلفون: Thomas J. McCown

المصدر: Neurotherapeutics. 6:307-311

مصطلحات موضوعية: Kainic acid, viruses, Genetic Vectors, Galanin, Biology, medicine.disease_cause, Green fluorescent protein, Viral vector, Gene product, Transduction (genetics), chemistry.chemical_compound, Transduction, Genetic, medicine, Animals, Humans, Pharmacology (medical), Adeno-associated virus, Pharmacology, Genetic Therapy, Theme 3: Gene Therapy, Transfection, Dependovirus, Rats, Cell biology, chemistry, Epilepsies, Partial, Neurology (clinical), Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33036a7f7b8bb6b20788b6f3e0dc8fa9
https://doi.org/10.1016/j.nurt.2009.01.004

المؤلفون: Boris Kantor, Brian Zeithaml, Matthew Bayer, Adam S. Cockrell, Tal Kafri, Thomas J. McCown, Xiangping Li, Hong Ma

المصدر: Molecular Therapy. 16(12):1968-1976

مصطلحات موضوعية: Male, Transgene, Genetic Vectors, Gene Expression, Genome, Viral, Biology, Article, Cell Line, Viral vector, Mice, 03 medical and health sciences, Transduction (genetics), 0302 clinical medicine, Plasmid, Transcription (biology), Gene expression, Drug Discovery, Genetics, Animals, Humans, Gene silencing, Molecular Biology, 030304 developmental biology, Pharmacology, 0303 health sciences, Lentivirus, Brain, Molecular biology, Rats, 3. Good health, Integrase, Liver, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Gene Deletion, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771bfb8fbe223a82b2473204ac4d79bb

المؤلفون: George R. Breese, Sophia T. Papadeas, Christopher Halloran, Thomas J. McCown, Bonita L. Blake

المصدر: The Journal of Comparative Neurology. 511:271-285

مصطلحات موضوعية: Agonist, medicine.medical_specialty, medicine.drug_class, Prefrontal Cortex, Biology, Article, Rats, Sprague-Dawley, Frontostriatal circuit, chemistry.chemical_compound, Dopamine receptor D1, Neurochemical, Dopamine, Internal medicine, medicine, Aminoacetonitrile, Animals, Protease Inhibitors, Phosphorylation, Oxidopamine, Prefrontal cortex, Receptor, Flavonoids, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Receptors, Dopamine D1, General Neuroscience, Dendrites, Rats, Endocrinology, medicine.anatomical_structure, chemistry, Dopamine Agonists, Sympatholytics, 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, Microtubule-Associated Proteins, Neuroscience, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b6a07b7b6d94fb2490f54eb04ea9e4
https://doi.org/10.1002/cne.21835

المؤلفون: Xiao Xiao, Xiaohuai Zhou, R. Jude Samulski, Chengwen Li, Xinghua Zeng, Thomas J. McCown, Zhenghong Fan

المصدر: Molecular Therapy. 16:494-499

مصطلحات موضوعية: Male, viruses, Genetic enhancement, Genetic Vectors, Green Fluorescent Proteins, Genome, Viral, Biology, medicine.disease_cause, Genome, Virus, Rats, Sprague-Dawley, Mice, Transduction (genetics), chemistry.chemical_compound, Transduction, Genetic, Reannealing, Drug Discovery, Genetics, medicine, Animals, Molecular Biology, Adeno-associated virus, Pharmacology, Models, Genetic, DNA synthesis, Muscles, Brain, Dependovirus, Molecular biology, Rats, Cell biology, Mice, Inbred C57BL, Liver, chemistry, DNA, Viral, Molecular Medicine, Female, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ea7ede0ec51391cec7af6cf5d24b80
https://doi.org/10.1038/sj.mt.6300397

المؤلفون: Thomas J. McCown

المصدر: Translational Neuroscience ISBN: 9781489976529

مصطلحات موضوعية: Surgical resection, Genetic enhancement, Pharmacology, Biology, medicine.disease_cause, medicine.disease, Bioinformatics, Viral vector, Epilepsy, Immune system, medicine, Focal Epilepsies, Gene therapy for epilepsy, Adeno-associated virus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7d13d22b7eaaf883d3ca998d6fbb4c7
https://doi.org/10.1007/978-1-4899-7654-3_9

المؤلفون: David Israeli, Steffan N. Ho, Tal Kafri, Thomas J. McCown, Karin Haack, Hong Ma, Adam S. Cockrell

المصدر: Molecular Therapy. 10(3):585-596

مصطلحات موضوعية: Transgene, Genetic enhancement, Genetic Vectors, Muscle Fibers, Skeletal, Biology, Response Elements, Cell Fusion, Transactivation, Mice, Genes, Reporter, Drug Discovery, Tumor Cells, Cultured, Genetics, Animals, Humans, Vector (molecular biology), Promoter Regions, Genetic, Gene, Molecular Biology, MyoD Protein, Pharmacology, Stem Cells, Translational readthrough, Gene Transfer Techniques, Brain, Cell Differentiation, Fibroblasts, Embryo, Mammalian, Fusion protein, Molecular biology, Rats, Doxycycline, HIV-1, Trans-Activators, Molecular Medicine, Expression cassette

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f7a5446e99e4b83e32d610945c3811