المؤلفون: Sarah Asemota, Wendy Effah, Kirsten L. Young, Jeremiah Holt, Linnea Cripe, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Keely Mcnamara, Daniel Johnson, Yinan Wang, Brandy Grimes, Yekta Khosrosereshki, T.J. Hollingsworth, Martin D. Fleming, Frances E. Pritchard, Ashley Hendrix, Farhan Khan, Meiyun Fan, Liza Makowski, Zheng Yin, Hironobu Sasano, D. Neil Hayes, Lawrence M. Pfeffer, Duane D. Miller, Ramesh Narayanan

المصدر: Cell Reports, Vol 42, Iss 12, Pp 113461- (2023)

مصطلحات موضوعية: CP: Cancer, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723014730; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/ac241ea52bf347e5b56f2020cc95e398

المؤلفون: Suriyan Ponnusamy, Sarah Asemota, Lee S. Schwartzberg, Fouzia Guestini, Keely M. McNamara, Mariaelena Pierobon, Alba Font-Tello, Xintao Qiu, Yingtian Xie, Prakash K. Rao, Thirumagal Thiyagarajan, Brandy Grimes, Daniel L. Johnson, Martin D. Fleming, Frances E. Pritchard, Michael P. Berry, Roy Oswaks, Richard E. Fine, Myles Brown, Hironobu Sasano, Emanuel F. Petricoin, Henry W. Long, Ramesh Narayanan

المصدر: iScience, Vol 21, Iss , Pp 341-358 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004219304183; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/dff52cda825c431a910313dacdb4bf32

المؤلفون: Tamara K Nowling, Jessalyn Rodgers, Thirumagal Thiyagarajan, Bethany Wolf, Evelyn Bruner, Kamala Sundararaj, Ivan Molano, Gary Gilkeson

المصدر: PLoS ONE, Vol 15, Iss 3, p e0230499 (2020)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d99d9223d9e24459993476584156eb5b

المؤلفون: Erin Morris Richard, Thirumagal Thiyagarajan, Marlene A Bunni, Fahmin Basher, Patrick O Roddy, Leah J Siskind, Paul J Nietert, Tamara K Nowling

المصدر: PLoS ONE, Vol 8, Iss 9, p e75175 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3769295?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/f8f21b58e3e24083812959898d64c66a

المؤلفون: Yali He (502021), Dong-Jin Hwang (1534081), Suriyan Ponnusamy (6112346), Thirumagal Thiyagarajan (456641), Michael L. Mohler (502018), Ramesh Narayanan (238761), Duane D. Miller (238777)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, truncation mutant-driven prostate c., pan-antagonist activities, Biological Evaluation, EnzR prostate cancers, LNCaP cells, degradation effects, 26 f, xenograft model, PC, androgen receptor degraders, Compound 26 f, UT -69, novel scaffold, tumor cell growth, UT -34, heteromonocyclic B-ring, novel SARDs, propanamide derivatives, binding SARDs

Relation: https://figshare.com/articles/journal_contribution/Exploration_and_Biological_Evaluation_of_Basic_Heteromonocyclic_Propanamide_Derivatives_as_SARDs_for_the_Treatment_of_Enzalutamide-Resistant_Prostate_Cancer/14995264

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00439.s001

المؤلفون: Ramesh Narayanan, Duane D. Miller, James T. Dalton, Tudor Moldoveanu, Wayne D. Tilley, Christopher Ledbetter, Robert W. Wake, Geetika Singh, Jayaprakash Pagadala, Charles B. Duke, Iain J. McEwan, Luke A. Selth, Yali He, Dong-Jin Hwang, Kate Watts, Thirumagal Thiyagarajan, Christopher C. Coss, Suriyan Ponnusamy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9751351163fd32e7ac2bddb726b12a58
https://doi.org/10.1158/0008-5472.22416662

المؤلفون: Ramesh Narayanan, Duane D. Miller, James T. Dalton, Tudor Moldoveanu, Wayne D. Tilley, Christopher Ledbetter, Robert W. Wake, Geetika Singh, Jayaprakash Pagadala, Charles B. Duke, Iain J. McEwan, Luke A. Selth, Yali He, Dong-Jin Hwang, Kate Watts, Thirumagal Thiyagarajan, Christopher C. Coss, Suriyan Ponnusamy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b4eabed8b39f4c2e494de62021040cfc
https://doi.org/10.1158/0008-5472.c.6509612.v1

المؤلفون: Ramesh Narayanan, Duane D. Miller, Iain J. McEwan, Robert H. Getzenberg, Lawrence M. Pfeffer, Ziyun Du, Daniel Johnson, Elias Fernandez, Bobby G. Sumpter, Vera Bocharova, Rene Houtman, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Suriyan Ponnusamy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9054e8abc24980aa48961a1579ce4617
https://doi.org/10.1158/1078-0432.22472238.v1

المؤلفون: Ramesh Narayanan, Duane D. Miller, James T. Dalton, Tudor Moldoveanu, Wayne D. Tilley, Christopher Ledbetter, Robert W. Wake, Geetika Singh, Jayaprakash Pagadala, Charles B. Duke, Iain J. McEwan, Luke A. Selth, Yali He, Dong-Jin Hwang, Kate Watts, Thirumagal Thiyagarajan, Christopher C. Coss, Suriyan Ponnusamy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0c6b7f62ec6c2aaa514bd22ff097be
https://doi.org/10.1158/0008-5472.22416659.v1

المؤلفون: Ramesh Narayanan, Duane D. Miller, Iain J. McEwan, Robert H. Getzenberg, Lawrence M. Pfeffer, Ziyun Du, Daniel Johnson, Elias Fernandez, Bobby G. Sumpter, Vera Bocharova, Rene Houtman, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Suriyan Ponnusamy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea976d84450fabcff4f2f1556976ea8
https://doi.org/10.1158/1078-0432.22472241.v1

المؤلفون: Ramesh Narayanan, Duane D. Miller, Iain J. McEwan, Robert H. Getzenberg, Lawrence M. Pfeffer, Ziyun Du, Daniel Johnson, Elias Fernandez, Bobby G. Sumpter, Vera Bocharova, Rene Houtman, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Suriyan Ponnusamy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c787e0289bf4d971824be0c4d9821752
https://doi.org/10.1158/1078-0432.c.6528168

المؤلفون: Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L. Young, Daniel L. Johnson, Vera Bocharova, Weidong Zhou, Abhinav K. Jain, Emanuel F. Petricoin, Zheng Yin, Lawrence M. Pfeffer, Duane D. Miller, Ramesh Narayanan

المصدر: Proceedings of the National Academy of Sciences. 120

مصطلحات موضوعية: Male, Prostatic Neoplasms, Castration-Resistant, Multidisciplinary, Receptors, Androgen, Cell Line, Tumor, Androgen Receptor Antagonists, Humans, Prostatic Neoplasms, Protein Isoforms, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb48da0e02b52914dfe845e12546b222
https://doi.org/10.1073/pnas.2211832120

المؤلفون: Michael L. Mohler, Ramesh Narayanan, Duane D. Miller, Dong Jin Hwang, Yali He, Thirumagal Thiyagarajan, Suriyan Ponnusamy

المصدر: J Med Chem

مصطلحات موضوعية: Male, medicine.drug_class, Antineoplastic Agents, Antiandrogen, Article, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, Prostate cancer, chemistry.chemical_compound, Prostate, Nitriles, Phenylthiohydantoin, Drug Discovery, LNCaP, Androgen Receptor Antagonists, medicine, Animals, Humans, Enzalutamide, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Prostatic Neoplasms, Neoplasms, Experimental, medicine.disease, Amides, Propanamide, Rats, Androgen receptor, HEK293 Cells, medicine.anatomical_structure, chemistry, Drug Resistance, Neoplasm, Receptors, Androgen, Benzamides, Cancer research, Molecular Medicine, Drug Screening Assays, Antitumor, Pharmacophore

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3694a2be4b545e13a35265286a84a3
https://doi.org/10.1021/acs.jmedchem.1c00439

المؤلفون: Alba Font-Tello, Yingtian Xie, Martin D. Fleming, Xintao Qiu, Henry W. Long, Suriyan Ponnusamy, Lee S. Schwartzberg, Brandy Grimes, Roy Oswaks, Prakash Rao, Mariaelena Pierobon, Myles Brown, Sarah Asemota, Michael P Berry, Daniel L. Johnson, Fouzia Guestini, Emanuel F. Petricoin, Keely May McNamara, Thirumagal Thiyagarajan, Frances E. Pritchard, Ramesh Narayanan, Richard E. Fine, Hironobu Sasano

المصدر: iScience
iScience, Vol 21, Iss, Pp 341-358 (2019)

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, Estrogen receptor, 02 engineering and technology, Article, 03 medical and health sciences, Breast cancer, Molecular Mechanism of Gene Regulation, Medicine, lcsh:Science, Molecular Biology, Cancer, Multidisciplinary, business.industry, 021001 nanoscience & nanotechnology, medicine.disease, Androgen receptor, 030104 developmental biology, Cistrome, Hormone receptor, Cancer research, lcsh:Q, FOXA1, 0210 nano-technology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3267aeded59c68868fd5136e8e3d2a57
http://europepmc.org/articles/PMC6889594

المؤلفون: Sarah Asemota, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Ramesh Narayanan

المصدر: Cancer Research. 82:1777-1777

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3215807e8c88f458e4f8ae9b2d5a5da3
https://doi.org/10.1158/1538-7445.am2022-1777

المؤلفون: Duane D. Miller, Michael L. Mohler, Dong Jin Hwang, Yali He, Thirumagal Thiyagarajan, Ramesh Narayanan, Suriyan Ponnusamy

المصدر: J Med Chem

مصطلحات موضوعية: Male, Antiandrogens, Antineoplastic Agents, Pharmacology, Pyrazole, 01 natural sciences, Article, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, Nitriles, Phenylthiohydantoin, medicine, Androgen Receptor Antagonists, Enzalutamide, Animals, Humans, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Antagonist, Prostatic Neoplasms, medicine.disease, Xenograft Model Antitumor Assays, 0104 chemical sciences, Rats, Androgen receptor, 010404 medicinal & biomolecular chemistry, chemistry, Drug Resistance, Neoplasm, Receptors, Androgen, Drug Design, Benzamides, Microsomes, Liver, Molecular Medicine, Pyrazoles, Pharmacophore, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab0d7542920c5aef5171618e5f1309c
https://pubmed.ncbi.nlm.nih.gov/33095584

المؤلفون: Jessalyn Rodgers, Ivan Molano, Tamara K. Nowling, Kamala P. Sundararaj, Thirumagal Thiyagarajan, Bethany J. Wolf, Gary S. Gilkeson, Evelyn Bruner

المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0230499 (2020)

مصطلحات موضوعية: 0301 basic medicine, Mice, Inbred MRL lpr, Phosphorous Acids, Physiology, Lupus nephritis, Pilot Projects, Urine, urologic and male genital diseases, Kidney, Biochemistry, Mice, 0302 clinical medicine, immune system diseases, Immune Physiology, Medicine and Health Sciences, skin and connective tissue diseases, Multidisciplinary, Proteinuria, Systemic lupus erythematosus, Catabolism, Lupus Nephritis, Lipids, 3. Good health, Body Fluids, Chemistry, 030220 oncology & carcinogenesis, Physical Sciences, Medicine, lipids (amino acids, peptides, and proteins), Female, medicine.symptom, Anatomy, Nephritis, Research Article, medicine.medical_specialty, Science, Lactosylceramides, Neuraminidase, Ceramides, Glycosphingolipids, Phosphates, 03 medical and health sciences, Oseltamivir, Internal medicine, Albumins, medicine, Animals, G(M3) Ganglioside, Sphingolipids, Ganglioside, business.industry, Chemical Compounds, Kidney metabolism, Biology and Life Sciences, Proteins, Kidneys, Renal System, medicine.disease, Sphingolipid, 030104 developmental biology, Endocrinology, Metabolism, business, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9cc32738a9e56bb5f6ec69c04b96b10
https://pubmed.ncbi.nlm.nih.gov/32187230

المؤلفون: Alexei P. Sokolov, Ivan Vlassiouk, Nickolay V. Lavrik, Georgios Polizos, Alexander Kisliuk, Bobby G. Sumpter, Duane D. Miller, A. A. Volodin, Dmitry Voylov, Thirumagal Thiyagarajan, Y.M. Shulga, Vera Bocharova, Ramesh Narayanan

المصدر: Nanoscale advances. 1(9)

مصطلحات موضوعية: Chemical imaging, Materials science, Resolution (electron density), General Engineering, Bioengineering, Nanotechnology, General Chemistry, Tip-enhanced Raman spectroscopy, Atomic and Molecular Physics, and Optics, Nanomaterials, symbols.namesake, Scanning probe microscopy, symbols, General Materials Science, Raman spectroscopy, Nanoscopic scale, Image resolution

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec14924bf509bd04667ab46338bc020f
https://pubmed.ncbi.nlm.nih.gov/36133556

المؤلفون: Robert H. Getzenberg, Vera Bocharova, Miller Duane D, Iain J. McEwan, René Houtman, Daniel L. Johnson, Suriyan Ponnusamy, Yali He, Elias J. Fernandez, Dong Jin Hwang, Thirumagal Thiyagarajan, Lawrence M. Pfeffer, Bobby G. Sumpter, Ramesh Narayanan, Ziyun Du

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(22)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Administration, Oral, Gene Expression, Neoplasm genetics, chemistry.chemical_compound, Prostate cancer, Mice, 0302 clinical medicine, User Facility, Receptors, Androgen, 030220 oncology & carcinogenesis, Benzamides, Protein Binding, Signal Transduction, medicine.medical_specialty, Proteasome Endopeptidase Complex, Antineoplastic Agents, 03 medical and health sciences, Internal medicine, Cell Line, Tumor, Nitriles, Phenylthiohydantoin, medicine, Androgen Receptor Antagonists, Biomarkers, Tumor, Enzalutamide, Animals, Humans, Dose-Response Relationship, Drug, business.industry, Ubiquitin, Prostatic Neoplasms, Differential regulation, Oak Ridge National Laboratory, medicine.disease, Xenograft Model Antitumor Assays, Rats, Androgen receptor, Abiraterone, Disease Models, Animal, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Mutation, Proteolysis, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efb0ad8c54fc87ba1cea9aebda1d2f2
https://pubmed.ncbi.nlm.nih.gov/31578494

المؤلفون: Duane D. Miller, James B. Breitmeyer, Ramesh Narayanan, Gunnar F. Kaufmann, Thirumagal Thiyagarajan, Dong Jin Hwang, Kirsten Young Young, Sarah Asemota, Suriyan Ponnusamy, Yali He

المصدر: Cancer Research. 81:1235-1235

مصطلحات موضوعية: Androgen receptor, Cancer Research, Oncology, business.industry, Cancer research, Androgen Receptor Positive, Medicine, business, Triple-negative breast cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2716013d825ec0d743603e39fe039ba8
https://doi.org/10.1158/1538-7445.am2021-1235