المؤلفون: Hysek, C.M., Simmler, L.D., Nicola, V.G., Vischer, N., Donzelli, M., Krähenbühl, S., Grouzmann, E., Huwyler, J., Hoener, M.C., Liechti, M.E.

المصدر: Plos One, vol. 7, no. 5, pp. e36476

مصطلحات موضوعية: 3,4-Methylenedioxyamphetamine/antagonists & inhibitors, 3,4-Methylenedioxyamphetamine/pharmacology, Adult, Biological Transport/drug effects, Female, Humans, Laboratories, Male, N-Methyl-3,4-methylenedioxyamphetamine/antagonists & inhibitors, Norepinephrine/secretion, Placebo Effect, Receptors, Adrenergic/metabolism, Serotonin/secretion, Serotonin Plasma Membrane Transport Proteins/metabolism, Thiophenes/adverse effects, Thiophenes/metabolism

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/22574166; info:eu-repo/semantics/altIdentifier/eissn/1932-6203; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_A3F591D6E74E0; https://serval.unil.ch/notice/serval:BIB_A3F591D6E74E; https://serval.unil.ch/resource/serval:BIB_A3F591D6E74E.P001/REF.pdf

الاتاحة: https://serval.unil.ch/notice/serval:BIB_A3F591D6E74E
https://doi.org/10.1371/journal.pone.0036476
https://serval.unil.ch/resource/serval:BIB_A3F591D6E74E.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_A3F591D6E74E0

المؤلفون: Sodhi, Jasleen K, Wong, Susan, Kirkpatrick, Donald S, Liu, Lichuan, Khojasteh, S Cyrus, Hop, Cornelis E C A, Barr, John T, Jones, Jeffrey P, Halladay, Jason S

مصطلحات موضوعية: Liver - enzymology, Protein-Tyrosine Kinases - metabolism, Humans, Molecular Conformation, Drugs, Investigational - pharmacokinetics, Substrate Specificity, Anti-Inflammatory Agents, Non-Steroidal - chemistry, Thiophenes - metabolism, Investigational - metabolism, Gene Expression Profiling, Pyrimidinones - metabolism, Non-Steroidal - blood, Investigational - analysis, Thiophenes - blood, Pyrimidinones - chemistry, Cytosol - enzymology, Investigational - chemistry, Protein Kinase Inhibitors - chemistry, Aldehyde Oxidase - chemistry, Protein-Tyrosine Kinases - chemistry, Non-Steroidal - metabolism, Protein Kinase Inhibitors - pharmacokinetics, Catalytic Domain, Biocatalysis, Drug Stability, Liver - metabolism, Models, Molecular

Relation: ispartof: Drug metabolism and disposition spage 908 epage 915 issue 6 vol 43; PMC4429680; WOS:000354187500013; 2376/101366; https://doi.org/10.1124/dmd.114.061804; 99900546534301842; alma:01ALLIANCE_WSU/bibs/99900546534301842

الاتاحة: https://doi.org/10.1124/dmd.114.061804
https://rex.libraries.wsu.edu/esploro/outputs/journalArticle/A-novel-reaction-mediated-by-human/99900546534301842

المؤلفون: Uppugunduri Satyanarayana, Chakradhara Rao, Rezgui, M, Diaz, PH, Tyagi, Anuj Kumar, Rousseau, J, Daali, Youssef, Duval, M, Bittencourt, H, Krajinovic, M, Ansari Djaberi, Marc Georges

المصدر: ISSN: 1470-269X ; Pharmacogenomics journal, vol. 14, no. 3 (2014) p. 263-271.

مصطلحات موضوعية: info:eu-repo/classification/ddc/615, info:eu-repo/classification/ddc/618, Adolescent, Antineoplastic Agents, Alkylating/therapeutic use, Busulfan/therapeutic use, Child, Preschool, Cytochrome P-450 Enzyme System/genetics, Female, Hematopoietic Stem Cell Transplantation, Humans, Infant, Newborn, Male, Polymorphism, Genetic, Thiophenes/metabolism, Transplantation Conditioning

Relation: info:eu-repo/semantics/altIdentifier/pmid/24165757; https://archive-ouverte.unige.ch/unige:48455; unige:48455

الاتاحة: https://archive-ouverte.unige.ch/unige:48455

المؤلفون: Anuj Kumar Tyagi, M A Rezgui, P H Diaz, Marc Ansari, Michel Duval, Chakradhara Rao S. Uppugunduri, Julie Rousseau, Maja Krajinovic, Youssef Daali, Henrique Bittencourt

المصدر: The Pharmacogenomics Journal, Vol. 14, No 3 (2014) pp. 263-71

مصطلحات موضوعية: Male, Transplantation Conditioning, CYP2B6, Adolescent, medicine.medical_treatment, Metabolite, Cytochrome P-450 Enzyme System/genetics, CYP2C19, Hematopoietic stem cell transplantation, Thiophenes, Biology, Pharmacology, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Antineoplastic Agents, Alkylating/therapeutic use, Genotype, Genetics, medicine, Humans, Allele, Child, CYP2C9, Antineoplastic Agents, Alkylating, Busulfan, ddc:615, ddc:618, Polymorphism, Genetic, Busulfan/therapeutic use, Hematopoietic Stem Cell Transplantation, Infant, Newborn, Infant, chemistry, Child, Preschool, Molecular Medicine, Female, Thiophenes/metabolism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be09d524ab37958fa88488fb0a17ad69
https://archive-ouverte.unige.ch/unige:48455

المؤلفون: Olmos, David, Barker, Douglas, Sharma, Rohini, Brunetto, Andre T, Yap, Timothy A, Taegtmeyer, Anne B, Barriuso, Jorge, Medani, Hanine, Degenhardt, Yan Y, Allred, Alicia J, Smith, Deborah A, Murray, Sharon C, Lampkin, Thomas A, Dar, Mohammed M, Wilson, Richard, de Bono, Johann S, Blagden, Sarah P

المصدر: Olmos , D , Barker , D , Sharma , R , Brunetto , A T , Yap , T A , Taegtmeyer , A B , Barriuso , J , Medani , H , Degenhardt , Y Y , Allred , A J , Smith , D A , Murray , S C , Lampkin , T A , Dar , M M , Wilson , R , de Bono , J S & Blagden , S P 2011 , ' Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced ....

مصطلحات موضوعية: Adenocarcinoma/drug therapy, Adult, Aged, 80 and over, Antineoplastic Agents/metabolism, Benzimidazoles/metabolism, Binding, Competitive, Cell Cycle Proteins/antagonists & inhibitors, Colorectal Neoplasms/drug therapy, Disease Progression, Female, Humans, Male, Maximum Tolerated Dose, Middle Aged, Neoplasms/drug therapy, Protein Kinase Inhibitors/metabolism, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Proto-Oncogene Proteins/antagonists & inhibitors, Substrate Specificity, Thiophenes/metabolism, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/f9070ec7-45a1-4859-ae6a-243f0e8a0d97
https://doi.org/10.1158/1078-0432.CCR-10-2946