المؤلفون: Vanden Broeck, Arnaud, McEwen, Alastair G, Chebaro, Yassmine, Potier, Noëlle, Lamour, Valérie

المصدر: Journal of Medicinal Chemistry, 62 (8), 4225-4231 (2019-04-25)

مصطلحات موضوعية: Aminocoumarins, Protein Subunits, 8L70Q75FXE (Adenosine Triphosphate), EC 5.99.1.3 (DNA Gyrase), PCH9QZ1IIH (coumermycin), Adenosine Triphosphate/chemistry/metabolism, Aminocoumarins/chemistry/metabolism, Binding Sites, DNA Gyrase/chemistry/metabolism, Dimerization, Escherichia coli/enzymology, Hydrogen Bonding, Molecular Dynamics Simulation, Protein Structure, Quaternary, Protein Subunits/chemistry/metabolism, Thermus thermophilus/enzymology, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: urn:issn:0022-2623; urn:issn:1520-4804

URL الوصول: https://orbi.uliege.be/handle/2268/323043

المؤلفون: Felix, J, Weinhäupl, K, Chipot, C, Dehez, F, Hessel, A, Gauto, DF, Morlot, C, Abian, O, Gutsche, I, Velazquez-Campoy, A, Schanda, P, Fraga, H

المساهمون: Instituto de Investigação e Inovação em Saúde

مصطلحات موضوعية: Allosteric Regulation, Bacterial Proteins / antagonists & inhibitors, Bacterial Proteins / chemistry, Catalytic Domain, Crystallography, X-Ray, Endopeptidase Clp / antagonists & inhibitors, Endopeptidase Clp / chemistry, Protease Inhibitors / chemistry, Thermus thermophilus / enzymology

وصف الملف: application/pdf

Relation: Science Advances, vol.5(9):eaaw3818; https://advances.sciencemag.org/content/5/9/eaaw3818; https://hdl.handle.net/10216/136238

الاتاحة: https://hdl.handle.net/10216/136238
https://doi.org/10.1126/sciadv.aaw3818

المؤلفون: Mazal, H., Iljina, M., Barak, Y., Elad, N., Rosenzweig, R., Goloubinoff, P., Riven, I., Haran, G.

المصدر: Nature communications, vol. 10, no. 1, pp. 1438

مصطلحات موضوعية: Allosteric Regulation, Binding Sites, Endopeptidase Clp/chemistry, Endopeptidase Clp/metabolism, Fluorescence Resonance Energy Transfer, HSP70 Heat-Shock Proteins/metabolism, Models, Molecular, Protein Aggregates, Protein Domains, Substrate Specificity, Thermus thermophilus/enzymology, Time Factors

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/30926805; info:eu-repo/semantics/altIdentifier/eissn/2041-1723; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_0B7396479C9A3; https://serval.unil.ch/notice/serval:BIB_0B7396479C9A; https://serval.unil.ch/resource/serval:BIB_0B7396479C9A.P001/REF.pdf

الاتاحة: https://serval.unil.ch/notice/serval:BIB_0B7396479C9A
https://doi.org/10.1038/s41467-019-09474-6
https://serval.unil.ch/resource/serval:BIB_0B7396479C9A.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0B7396479C9A3

المؤلفون: Sharma, V., Belevich, G., Gamiz-Hernandez, A. P., Rog, T., Vattulainen, Ilpo, Verkhovskaya, M. L., Wikstrom, M., Hummer, G., Kaila, V. R. I.

المصدر: Sharma , V , Belevich , G , Gamiz-Hernandez , A P , Rog , T , Vattulainen , I , Verkhovskaya , M L , Wikstrom , M , Hummer , G & Kaila , V R I 2015 , ' Redox-induced activation of the proton pump in the respiratory complex I ' , PNAS , vol. 112 , no. 37 , pp. 11571-11576 . https://doi.org/10.1073/pnas.1503761112

مصطلحات موضوعية: Cell respiration, Electron transfer, Molecular dynamics simulations, NADH-quinone oxidoreductase, QM/MM simulations, Protein Structure, Tertiary, Electron Transport, Temperature, Mutagenesis, Site-Directed, Oxidation-Reduction, Proton Pumps/physiology, Escherichia coli/metabolism, Static Electricity, Molecular Dynamics Simulation, Electron Transport Complex I/physiology, Lipid Bilayers/chemistry, X-Rays, Protein Binding, Photosynthetic Reaction Center Complex Proteins/physiology, Thermus thermophilus/enzymology

وصف الملف: application/pdf

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/c1af4c89-954d-4636-ab99-a0ec47140238
https://doi.org/10.1073/pnas.1503761112
https://findresearcher.sdu.dk/ws/files/129888157/Redox_induced_activation_of_the_proton_pump_in_the_respiratory_complex_I.pdf

المؤلفون: Graczer, E., Konarev, P. V., Szimler, T., Bacso, A., Bodonyi, A., Svergun, D. I., Zavodszky, P., Vas, M.

المصدر: FEBS letters 585, 3297-3302 (2011). doi:10.1016/j.febslet.2011.09.013

مصطلحات موضوعية: info:eu-repo/classification/ddc/570, 3-Isopropylmalate Dehydrogenase: chemistry, Bacterial Proteins: chemistry, Crystallography, X-Ray, Escherichia coli: enzymology, Metals: chemistry, Protein Structure, Tertiary, Thermus thermophilus: enzymology, Bacterial Proteins, Metals, 3-Isopropylmalate Dehydrogenase

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0014-5793; info:eu-repo/semantics/altIdentifier/wos/WOS:000296514100023; info:eu-repo/semantics/altIdentifier/pmid/pmid:21939659; info:eu-repo/semantics/altIdentifier/issn/1873-3468; https://bib-pubdb1.desy.de/record/139261; https://bib-pubdb1.desy.de/search?p=id:%22PHPPUBDB-23053%22

الاتاحة: https://bib-pubdb1.desy.de/record/139261
https://bib-pubdb1.desy.de/search?p=id:%22PHPPUBDB-23053%22

المؤلفون: Audrey Hessel, Katharina Weinhäupl, Adrián Velázquez-Campoy, Christophe Chipot, Cécile Morlot, Paul Schanda, Jan Felix, François Dehez, Olga Abian, Hugo Pacheco de Freitas Fraga, Irina Gutsche, Diego F. Gauto

المساهمون: Instituto de Investigação e Inovação em Saúde, Laboratory for Protein Biochemistry and Biomolecular Engineering, Department of Biochemistry, Physiology and Microbiology, Universiteit Gent = Ghent University [Belgium] (UGENT), Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique et Chimie Théoriques (LPCT), Institut de Chimie du CNRS (INC)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Department of Physics [Illinois at Urbana-Champaign, USA], University of Illinois at Urbana-Champaign [Urbana], University of Illinois System-University of Illinois System, Laboratoire International Associé CNRS and University of Illinois at Urbana−Champaign, Vandoeuvre-les-Nancy F-54506, France., Unidad Asociada IQFR-CSIC-BIFI [Zaragoza, Spain], University of Zaragoza - Universidad de Zaragoza [Zaragoza]-Instituto de Biocomputación y Física de Sistemas Complejos - BIFI [Zaragoza, Spain], Grenoble Partnership for Structural Biology (PSB), Innovative EM/NMR approach for the characterization of the drug target ClpP APPID: 301, ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010), ANR-10-LABX-0049,GRAL,Grenoble Alliance for Integrated Structural Cell Biology(2010), Centre National de la Recherche Scientifique (France), Agence Nationale de la Recherche (France), Ministerio de Economía y Competitividad (España), Instituto de Salud Carlos III, European Science Foundation, European Commission, SCOAP, Universiteit Gent = Ghent University (UGENT), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), University of Illinois System

المصدر: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
'Science Advances ', vol: 5, pages: eaaw3818-1-eaaw3818-19 (2019)
Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2019, 5 (9), pp.eaaw3818. ⟨10.1126/sciadv.aaw3818⟩
SCIENCE ADVANCES
Digital.CSIC. Repositorio Institucional del CSIC
Science Advances, 2019, 5 (9), pp.eaaw3818. ⟨10.1126/sciadv.aaw3818⟩

مصطلحات موضوعية: DYNAMICS, [SDV]Life Sciences [q-bio], medicine.medical_treatment, Crystallography, X-Ray, Biochemistry, 01 natural sciences, Serine, Structural Biology, Catalytic Domain, CRYSTAL-STRUCTURE, Research Articles, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Chemistry, Thermus thermophilus / enzymology, SciAdv r-articles, Endopeptidase Clp, Bacterial Proteins / chemistry, 3. Good health, INSIGHTS, Drug development, ESCHERICHIA-COLI, NMR-SPECTROSCOPY, Endopeptidase Clp / antagonists & inhibitors, Research Article, medicine.drug, PROTEINS, Protein subunit, Allosteric regulation, TUBERCULOSIS, 010402 general chemistry, 03 medical and health sciences, Bacterial Proteins, Allosteric Regulation, medicine, Protease Inhibitors, Bacterial Proteins / antagonists & inhibitors, 030304 developmental biology, COMPLEX, Protease, 010405 organic chemistry, Thermus thermophilus, Biology and Life Sciences, Active site, Isothermal titration calorimetry, 0104 chemical sciences, MODEL, SERINE-PROTEASE, Enzyme, Endopeptidase Clp / chemistry, Chaperone (protein), Proteasome inhibitor, biology.protein, Biophysics, Protease Inhibitors / chemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1324138b0f4d564dc88daa4ccd2c80

المؤلفون: Lönn, Anna, Gárdonyi, Márk, van Zyl, Willem, Hahn-Hägerdal, Bärbel, Otero, Ricardo Cordero

المصدر: European Journal of Biochemistry. 269(1):157-163

مصطلحات موضوعية: Hydrogen-Ion Concentration, Kinetics, Magnesium : pharmacology, Manganese : pharmacology, Mutagenesis, Polymerase Chain Reaction, Support Non-U.S. Gov't, Xylitol : pharmacology, Thermus thermophilus : enzymology, Enzyme Stability, Cold, Aldose-Ketose Isomerases : chemistry : genetics : metabolism, Teknik, Industriell bioteknik, Engineering and Technology, Industrial Biotechnology

URL الوصول: https://lup.lub.lu.se/record/106747
http://dx.doi.org/10.1046/j.0014-2956.2002.02631.x

المؤلفون: Graczer, E., Merli, A., Singh, R. K., Karuppasamy, M., Zavodszky, P., Weiss, M. S., Vas, M.

المصدر: Molecular BioSystems 7, 1646 (2011). doi:10.1039/c0mb00346h

مصطلحات موضوعية: info:eu-repo/classification/ddc/540, 3-Isopropylmalate Dehydrogenase: chemistry, 3-Isopropylmalate Dehydrogenase: metabolism, Bacterial Proteins: chemistry, Bacterial Proteins: metabolism, Crystallization, Crystallography, X-Ray, Humans, Malates: chemistry, Malates: metabolism, Manganese: chemistry, Manganese: metabolism, Microspectrophotometry, Models, Molecular, NAD: chemistry, NAD: metabolism, Protein Binding, Protein Conformation, Protein Folding, Protein Multimerization, Protein Structure, Secondary, Tertiary, Substrate Specificity, Thermus thermophilus: enzymology, Bacterial Proteins, Malates, NAD

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:21387033; info:eu-repo/semantics/altIdentifier/issn/1742-2051; info:eu-repo/semantics/altIdentifier/wos/WOS:000289367200026; info:eu-repo/semantics/altIdentifier/issn/1742-206X; https://bib-pubdb1.desy.de/record/144033; https://bib-pubdb1.desy.de/search?p=id:%22PHPPUBDB-25754%22

الاتاحة: https://bib-pubdb1.desy.de/record/144033
https://bib-pubdb1.desy.de/search?p=id:%22PHPPUBDB-25754%22

المؤلفون: Droogmans, Louis, Roovers, Martine, Bujnicki, Janusz Marek, Tricot, Catherine, Hartsch, Thomas, Stalon, Victor, Grosjean, Henri

المصدر: Nucleic acids research, 31 (8

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Amino Acid Sequence, Cell Division -- genetics, Chromatography, Gel, Cloning, Molecular, Dimerization, Electrophoresis, Polyacrylamide Gel, Hot Temperature, Molecular Sequence Data, Mutation, Phenotype, RNA, Transfer, Asp -- metabolism, Sequence Homology, Amino Acid, Temperature, Thermus thermophilus -- enzymology, Thermus thermophilus -- genetics, Thermus thermophilus -- growth & development, tRNA Methyltransferases -- genetics, tRNA Methyltransferases -- isolation & purification, tRNA Methyltransferases -- metabolism

وصف الملف: 1 full-text file(s): application/pdf

Relation: uri/info:doi/10.1093/nar/gkg314; uri/info:pmid/12682365; uri/info:scp/0037799504; uri/info:pmcid/PMC153742; https://dipot.ulb.ac.be/dspace/bitstream/2013/50454/4/PMC153742.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50454

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50454
https://dipot.ulb.ac.be/dspace/bitstream/2013/50454/4/PMC153742.pdf

المؤلفون: Barraud, Pierre, Golinelli-Pimpaneau, Béatrice, Atmanene, Cédric, Sanglier, Sarah, Van Dorsselaer, Alain, Droogmans, Louis, Dardel, Frédéric, Tisné, Carine

المصدر: Journal of Molecular Biology, 377 (2

مصطلحات الفهرس: Sciences bio-médicales et agricoles, Adenine -- chemistry, Adenine -- metabolism, Amino Acid Sequence, Animals, Binding Sites, Biophysical Phenomena, Biophysics, Catalysis, Conserved Sequence, Crystallography, X-Ray, Humans, Models, Molecular, Molecular Sequence Data, Mutation -- genetics, Mycobacterium tuberculosis -- enzymology, Osmolar Concentration, Protein Binding, Protein Structure, Quaternary, Protein Structure, Tertiary, RNA, Transfer -- chemistry, RNA, Transfer -- metabolism, Sequence Alignment, Spectrometry, Mass, Electrospray Ionization, Static Electricity, Structural Homology, Protein, Substrate Specificity, Thermus thermophilus -- enzymology, Thermus thermophilus -- genetics, tRNA Methyltransferases -- chemistry, tRNA Methyltransferases -- genetics, tRNA Methyltransferases -- metabolism, m1A58 methyltransferase, noncovalent mass spectrometry, protein-RNA interactions, TrmI, X-ray structure, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: https://dipot.ulb.ac.be/dspace/bitstream/2013/50478/1/Elsevier_25506.pdf
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/50478
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL