يعرض 1 - 18 نتائج من 18 نتيجة بحث عن '"Theresa E. Baker"', وقت الاستعلام: 0.74s تنقيح النتائج
  1. 1
    Data from Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non–Small Cell Lung Cancer

    المؤلفون: Victor M. Rivera, Xiaotian Zhu, Kwok-kin Wong, Shengwu Liu, Robert J. Griffin, Johara Chouitar, Michael Fitzgerald, William C. Shakespeare, David Dalgarno, Tim Clackson, Narayana I. Narasimhan, Biplab Das, Stephan G. Zech, Matthew T. Greenfield, Feng Li, Yongbo Hu, Wei-Sheng Huang, Sen Zhang, Yaoyu Ning, Sara Nadworny, Scott D. Wardwell, Shuai Li, Alexandra E. Gould, Theresa E. Baker, Sylvie Vincent, Francois Gonzalvez

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1233d4a09c246c7e577a052bb61a6464
    https://doi.org/10.1158/2159-8290.c.6549370.v1

    View record in OpenAIRE

    أضف إلى المفضلة
  2. 2
    Supplementary Data from Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non–Small Cell Lung Cancer

    المؤلفون: Victor M. Rivera, Xiaotian Zhu, Kwok-kin Wong, Shengwu Liu, Robert J. Griffin, Johara Chouitar, Michael Fitzgerald, William C. Shakespeare, David Dalgarno, Tim Clackson, Narayana I. Narasimhan, Biplab Das, Stephan G. Zech, Matthew T. Greenfield, Feng Li, Yongbo Hu, Wei-Sheng Huang, Sen Zhang, Yaoyu Ning, Sara Nadworny, Scott D. Wardwell, Shuai Li, Alexandra E. Gould, Theresa E. Baker, Sylvie Vincent, Francois Gonzalvez

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b1686b17282cc4afaa22ed044b1306
    https://doi.org/10.1158/2159-8290.22540399

    View record in OpenAIRE

    أضف إلى المفضلة
  3. 3
    Table S2 from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc292ba115983e2e9d41bf0078c4067
    https://doi.org/10.1158/0008-5472.22490195

    View record in OpenAIRE

    أضف إلى المفضلة
  4. 4
    Data from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3282ae56d3b65e02abbca4ecf45fe434
    https://doi.org/10.1158/0008-5472.c.6533114

    View record in OpenAIRE

    أضف إلى المفضلة
  5. 5
    Table S1 from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e086b8cab50add0e7a783e32ef6c80bf
    https://doi.org/10.1158/0008-5472.22490198

    View record in OpenAIRE

    أضف إلى المفضلة
  6. 6
    Figure S1 from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b801af9cd01bb649be8ad1b6d441cd
    https://doi.org/10.1158/0008-5472.22490216

    View record in OpenAIRE

    أضف إلى المفضلة
  7. 7
    Figure S2 from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f59c15053d678814c26ceef9147007
    https://doi.org/10.1158/0008-5472.22490210

    View record in OpenAIRE

    أضف إلى المفضلة
  8. 8
    Figure S3 from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e797d2a6822f5aa7293a8274167b68d
    https://doi.org/10.1158/0008-5472.22490207.v1

    View record in OpenAIRE

    أضف إلى المفضلة
  9. 9
    Figure S4 from Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Kwok-Kin Wong, Sylvie Vincent, Rachael Brake, Victor M. Rivera, Haiquan Chen, Francois Gonzalvez, Sittinon Tang, Eleni Papadopoulos, Cassandra Thakurdin, Val Pyon, Hai Hu, Hailin Ding, Yuanwang Pan, Hua Zhang, Fei Li, Theresa E. Baker, Zhendong Gao, Jiehui Deng, David Peng, Jiansheng Wu, Johara Chouitar, Shougen Cao, Kwan Ho Tang, Chengwei Peng, Shengwu Liu, Michael Fitzgerald, Ting Chen, Shuai Li, Han Han

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41427e4f857e13886ba75108bf9e93eb
    https://doi.org/10.1158/0008-5472.22490204.v1

    View record in OpenAIRE

    أضف إلى المفضلة
  10. 10
    Targeting HER2 Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib

    المؤلفون: Hua Zhang, Haiquan Chen, Sittinon Tang, Shougen Cao, Yuanwang Pan, Victor M. Rivera, Shuai Li, Fei Li, Kwan Ho Tang, Hai Hu, Chengwei Peng, Francois Gonzalvez, Hailin Ding, Jiehui Deng, Johara Chouitar, Han Han, Sylvie Vincent, Theresa E. Baker, Michael Fitzgerald, Val Pyon, Ting Chen, Zhendong Gao, Rachael L. Brake, Eleni Papadopoulos, David H. Peng, Jiansheng Wu, Cassandra Thakurdin, Kwok-Kin Wong, Shengwu Liu

    المصدر: Cancer Research. 81:5311-5324

    مصطلحات موضوعية: Cancer Research, medicine.drug_class, Afatinib, T cell, Poziotinib, Biology, medicine.disease, Tyrosine-kinase inhibitor, Exon, medicine.anatomical_structure, Oncology, Neratinib, medicine, Cancer research, Adenocarcinoma, skin and connective tissue diseases, Lung cancer, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f7997759bba1b98f3f10b2c5af242a6
    https://doi.org/10.1158/0008-5472.can-21-1526

    View record in OpenAIRE

    أضف إلى المفضلة
  11. 11
    Discovery of mobocertinib, a potent, oral inhibitor of EGFR exon 20 insertion mutations in non–small cell lung cancer

    المؤلفون: Wei-Sheng, Huang, Feng, Li, Yongjin, Gong, Yun, Zhang, Willmen, Youngsaye, Yongjin, Xu, Xiaotian, Zhu, Matthew T, Greenfield, Anna, Kohlmann, Paul M, Taslimi, Angela, Toms, Stephan G, Zech, Tianjun, Zhou, Biplab, Das, Hyun G, Jang, Meera, Tugnait, Yihua E, Ye, Francois, Gonzalvez, Theresa E, Baker, Sara, Nadworny, Yaoyu, Ning, Scott D, Wardwell, Sen, Zhang, Alexandra E, Gould, Yongbo, Hu, Weston, Lane, Robert J, Skene, Hua, Zou, Tim, Clackson, Narayana I, Narasimhan, Victor M, Rivera, David C, Dalgarno, William C, Shakespeare

    المصدر: Bioorganic & Medicinal Chemistry Letters. 80:129084

    مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36257c29b5ae4b54e2d345df53177fd7
    https://doi.org/10.1016/j.bmcl.2022.129084

    View record in OpenAIRE

    أضف إلى المفضلة
  12. 12
    Targeting

    المؤلفون: Han, Han, Shuai, Li, Ting, Chen, Michael, Fitzgerald, Shengwu, Liu, Chengwei, Peng, Kwan Ho, Tang, Shougen, Cao, Johara, Chouitar, Jiansheng, Wu, David, Peng, Jiehui, Deng, Zhendong, Gao, Theresa E, Baker, Fei, Li, Hua, Zhang, Yuanwang, Pan, Hailin, Ding, Hai, Hu, Val, Pyon, Cassandra, Thakurdin, Eleni, Papadopoulos, Sittinon, Tang, Francois, Gonzalvez, Haiquan, Chen, Victor M, Rivera, Rachael, Brake, Sylvie, Vincent, Kwok-Kin, Wong

    المصدر: Cancer Res

    مصطلحات موضوعية: Lung Neoplasms, Receptor, ErbB-2, Adenocarcinoma of Lung, Apoptosis, Exons, Mice, SCID, Ado-Trastuzumab Emtansine, Xenograft Model Antitumor Assays, Article, Gene Expression Regulation, Neoplastic, Mice, INDEL Mutation, Mice, Inbred NOD, Antibodies, Bispecific, Antineoplastic Combined Chemotherapy Protocols, Tumor Cells, Cultured, Animals, Humans, Female, skin and connective tissue diseases, Cell Proliferation

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c6a7d5e6cd053681006543a5c3a6881f
    https://pubmed.ncbi.nlm.nih.gov/34380634

    View record in OpenAIRE

    أضف إلى المفضلة
  13. 13
    Mobocertinib (TAK-788): A Targeted Inhibitor of

    المؤلفون: Francois, Gonzalvez, Sylvie, Vincent, Theresa E, Baker, Alexandra E, Gould, Shuai, Li, Scott D, Wardwell, Sara, Nadworny, Yaoyu, Ning, Sen, Zhang, Wei-Sheng, Huang, Yongbo, Hu, Feng, Li, Matthew T, Greenfield, Stephan G, Zech, Biplab, Das, Narayana I, Narasimhan, Tim, Clackson, David, Dalgarno, William C, Shakespeare, Michael, Fitzgerald, Johara, Chouitar, Robert J, Griffin, Shengwu, Liu, Kwok-Kin, Wong, Xiaotian, Zhu, Victor M, Rivera

    المصدر: Cancer discovery. 11(7)

    مصطلحات موضوعية: Aniline Compounds, Indoles, Lung Neoplasms, Antineoplastic Agents, Exons, Xenograft Model Antitumor Assays, ErbB Receptors, Mice, Mutagenesis, Insertional, Pyrimidines, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Animals, Humans

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9a090d0d5999a1e6356828f965f2c661
    https://pubmed.ncbi.nlm.nih.gov/34284994

    View record in OpenAIRE

    أضف إلى المفضلة
  14. 14
    MA11.02 Targeting HER2 Exon 20–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor, Mobocertinib

    المؤلفون: Hao Chen, Zhendong Gao, Hailin Ding, Jiansheng Wu, Yuanwang Pan, Michael Fitzgerald, Sittinon Tang, Kwan Ho Tang, Cassandra Thakurdin, Sylvie Vincent, Rachael L. Brake, Kwok K. Wong, Ting Chen, S. Cao, Val Pyon, C. Peng, Jiehui Deng, Victor M. Rivera, Theresa E. Baker, Fei Li, Hai Hu, Francois Gonzalvez, David H. Peng, Simin Liu, Shihua Li, Eleni Papadopoulos, Johara Chouitar, Han Han, Hua Zhang

    المصدر: Journal of Thoracic Oncology. 16:S918

    مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Lung, business.industry, medicine.drug_class, Mutant, medicine.disease, Tyrosine-kinase inhibitor, Exon, medicine.anatomical_structure, Oncology, medicine, Cancer research, Adenocarcinoma, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6eb5a3c4d01d3f8ebaf556b2da7c9fec
    https://doi.org/10.1016/j.jtho.2021.08.164

    View record in OpenAIRE

    أضف إلى المفضلة
  15. 15
    Acquisition of a single EZH2 D1 domain mutation confers acquired resistance to EZH2-targeted inhibitors

    المؤلفون: Justin R. Pritchard, Francois Gonzalvez, Theresa E. Baker, Sujata Nerle, Victor M. Rivera, Boyang Zhao, Andrew P. Garner

    المصدر: Oncotarget

    مصطلحات موضوعية: Indoles, Time Factors, Pyridones, Morpholines, Mutant, Antineoplastic Agents, Drug resistance, macromolecular substances, Transfection, RNA interference, Neoplasms, Humans, cancer, Enhancer of Zeste Homolog 2 Protein, Epigenetics, Molecular Targeted Therapy, EZH2, Allele, Enzyme Inhibitors, Genetics, drug resistance, biology, Dose-Response Relationship, Drug, epigenetics, Biphenyl Compounds, Polycomb Repressive Complex 2, Neoplasm Proteins, Protein Structure, Tertiary, HEK293 Cells, Oncology, Drug Resistance, Neoplasm, Histone methyltransferase, Benzamides, Mutation, biology.protein, RNA Interference, PRC2, Protein Binding, Transcription Factors, Research Paper

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56342c1a883f8e0267d49b505592957d
    https://pubmed.ncbi.nlm.nih.gov/26360609

    View record in OpenAIRE

    أضف إلى المفضلة
  16. 16
    Abstract 2644: AP32788, a potent, selective inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, in preclinical models

    المؤلفون: Biplab Das, Yun Zhang, Theresa E. Baker, Xiaotian Zhu, Emily Y. Ye, Meera Tugnait, Wei-Sheng Huang, Tianjun Zhou, Yongjin Xu, Narayana I. Narasimhan, Yaoyu Ning, Hyun Gyung Jang, William C. Shakespeare, David C. Dalgarno, Paul M. Taslimi, Scott Wardwell, Sen Zhang, Sara Nadworny, Victor M. Rivera, Francois Gonzalvez, Willmen Youngsaye, Anna Kohlmann, Feng Li, Gong Yongjin, Matthew T. Greenfield, Stephan G. Zech

    المصدر: Cancer Research. 76:2644-2644

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Mutation, Afatinib, Biology, Resistance mutation, medicine.disease_cause, Molecular biology, 03 medical and health sciences, Exon, T790M, 030104 developmental biology, 0302 clinical medicine, Gefitinib, Oncology, 030220 oncology & carcinogenesis, medicine, Erlotinib, Tyrosine kinase, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd3fc4ce5785604d73f92e73f1327360
    https://doi.org/10.1158/1538-7445.am2016-2644

    View record in OpenAIRE

    أضف إلى المفضلة
  17. 17
    Abstract 3597: EZH2 D1 domain mutants confer acquired resistance to EZH2-targeted inhibitors and reprogram B-cell transcription

    المؤلفون: Theresa E. Baker, Francois Gonzalvez, Justin R. Pritchard, Victor M. Rivera, Andrew P. Garner

    المصدر: Cancer Research. 75:3597-3597

    مصطلحات موضوعية: Genetics, Cancer Research, medicine.anatomical_structure, Acquired resistance, Oncology, Transcription (biology), Mutant, EZH2, medicine, Biology, B cell

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e1374f323d2ea3e565642246b1f6c95c
    https://doi.org/10.1158/1538-7445.am2015-3597

    View record in OpenAIRE

    أضف إلى المفضلة
  18. 18
    Comparative TKI Profiling Analyses to Explore Potential Mechanisms of Ponatinib-Associated Arterial Thrombotic Events

    المؤلفون: Theresa E. Baker, Joseph M. Gozgit, Justin R. Pritchard, Francois Gonzalvez, Graeme Hodgson, Victor M. Rivera

    المصدر: Blood. 124:1783-1783

    مصطلحات موضوعية: business.industry, medicine.drug_class, Sunitinib, Immunology, Ponatinib, Imatinib, Cell Biology, Hematology, Pharmacology, Biochemistry, Tyrosine-kinase inhibitor, Dasatinib, chemistry.chemical_compound, Imatinib mesylate, chemistry, Nilotinib, hemic and lymphatic diseases, Medicine, business, Bosutinib, medicine.drug

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::275c57d5f68c4199fdb2fe2fb9e36dcb
    https://doi.org/10.1182/blood.v124.21.1783.1783

    View record in OpenAIRE

    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS – أرسل هذا البحث بالبريد الإلكتروني – حفظ البحث – جدول التنبيهات: لا شيء