المؤلفون: Kaori Kawakami, Tomomitsu Miyasaka, Yutaka Nakamura, Hirohito Metoki, Satoshi Miyata, Miki Sato, Ichiro Sora, Kohei Yamauchi, Kazuyoshi Kawakami, Julie A. Blendy, Tasuku Kawano, Hiroaki Shimokawa, Motoaki Takayanagi, Isao Ohno, Tomoko Takahashi

المصدر: Allergology International, Vol 71, Iss 1, Pp 55-65 (2022)

مصطلحات موضوعية: Allergic asthma, A118G, OPRM1, Polymorphism, Th2 cell differentiation, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1323893021000940; https://doaj.org/toc/1323-8930

URL الوصول: https://doaj.org/article/50b5c152571a44338ba2914601cc70e4

المؤلفون: Tianyue Wang, Qianlan Zhou, Yunxiao Shang

المصدر: Journal of Innate Immunity, Pp 1-11 (2020)

مصطلحات موضوعية: mirna-451a, ets proto-oncogene 1, childhood asthma, th2 cell differentiation, type 2 inflammation, Medicine, Internal medicine, RC31-1245

وصف الملف: electronic resource

Relation: https://www.karger.com/Article/FullText/509714; https://doaj.org/toc/1662-811X; https://doaj.org/toc/1662-8128

URL الوصول: https://doaj.org/article/19826c20fabf4a03bff58c7163e3c0cf

المؤلفون: Jan E. de Vries

المصدر: Allergology International, Vol 45, Iss 3, Pp 117-123 (1996)

مصطلحات موضوعية: inhibition of allergic responses, allergen-specific Th2 cells, IL-4 and IL-13 receptor antagonist, IgE synthesis, Th2 cell anergy, Th2 cell differentiation, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1323893015317007; https://doaj.org/toc/1323-8930

URL الوصول: https://doaj.org/article/4d33dcf547c947b2976f0b45a9de3239

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/M2_markers_in_BMDM_from_WT_and_i_NOS1_i_sup_sup_mice_/16700559

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g001

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/Neither_the_phosphorylation_of_STAT6_nor_the_levels_of_PPAR_were_affected_in_IL4-stimulated_i_NOS1_i_sup_sup_macrophages_/16700562

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g002

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/Integrated_analysis_of_DEGs_in_WT_and_i_NOS1_i_sup_sup_macrophages_post-LPS_stimulation_/16700565

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g003

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/NOS1_deficiency_affects_several_pathways_related_to_macrophage_polarization_towards_M1_after_2_h_of_LPS_stimulation_/16700571

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g005

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/Functional_classification_of_the_DEGs_obtained_from_the_comparison_of_WT_and_i_NOS1_i_sup_sup_macrophages_stimulated_with_LPS_for_2_A_and_8_h_B_/16700568

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g004

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/Analysis_of_pathways_affected_by_NOS1_knockout_post_8h_LPS_stimulation_/16700574

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g006

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/Interaction_network_analysis_for_DEGs_post_2_h_A_and_8_h_B_LPS_stimulation_/16700577

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g007

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/RT-qPCR_validation_of_selected_DEGs_in_WT_and_i_NOS1_i_sup_sup_macrophages_stimulated_with_LPS_for_2_8_h_or_not_stimulated_0_h_/16700580

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g008

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/Immunoblotting_analysis_of_NOS2_p65_and_SOCS1_in_WT_and_i_NOS1_i_sup_i_i_sup_macrophages_stimulated_with_LPS_or_not_/16700583

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g009

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/figure/A_model_of_the_role_of_NOS1_in_macrophage_polarization_/16700586

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.g010

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/dataset/Primers_used_to_quantify_mRNA_levels_/16700589

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.t001

المؤلفون: Pingan Chang (11502045), Hao Gao (154820), Quan Sun (175631), Xiaohong He (646305), Feifei Huang (2355883)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, th2 cell differentiation, reveal novel insights, polarized macrophages stimulated, knockout mouse macrophages, distinct biological functions, biological processes related, 8 h post, 2 h post, time quantitative pcr, major pathways affected, main pathways affected, longer stimulation time, differentially expressed genes, m2 macrophage polarization, m1 macrophage polarization, div >< p, ampk signaling pathway, affected genes, signaling pathway, first time, responsive genes

Relation: https://figshare.com/articles/dataset/Summary_of_mRNA-seq_data_/16700592

الاتاحة: https://doi.org/10.1371/journal.pone.0257908.t002

المؤلفون: Yunxiao Shang, Tianyue Wang, Qianlan Zhou

المصدر: J Innate Immun
Journal of Innate Immunity, Pp 1-11 (2020)

مصطلحات موضوعية: mirna-451a, 0301 basic medicine, CD4-Positive T-Lymphocytes, Male, lcsh:Internal medicine, type 2 inflammation, T cell, Cellular differentiation, Population, Cell, lcsh:Medicine, Down-Regulation, Inflammation, GATA3 Transcription Factor, Proto-Oncogene Mas, th2 cell differentiation, Proto-Oncogene Protein c-ets-1, 03 medical and health sciences, 0302 clinical medicine, Th2 Cells, Downregulation and upregulation, childhood asthma, medicine, Immunology and Allergy, Humans, lcsh:RC31-1245, education, Child, ets proto-oncogene 1, Cells, Cultured, education.field_of_study, Interleukin-13, Chemistry, lcsh:R, GATA3, Interleukin, Cell Differentiation, Molecular biology, Asthma, Up-Regulation, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, 030228 respiratory system, Child, Preschool, Female, medicine.symptom, Interleukin-5, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1d2c9fc100a540bf281b133d5e224e
https://pubmed.ncbi.nlm.nih.gov/33271553

المؤلفون: Zhihai Wu, Zhiqiang Luo, Wen Sun, Yuanyuan Shi, Qi Ding

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Plant Biology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, treat respiratory diseases, sup >+, stat6 signaling pathway, stat signaling pathway, network pharmacology revealed, integrating network pharmacology, established using ovalbumin, bronchoalveolar lavage fluid, allergic asthmatic mice, th2 cell differentiation, primary biological process, improving allergic asthma, allergic asthma, biological effects, western blotting, therapeutic potential, th2 cells

Relation: https://figshare.com/articles/journal_contribution/Integrating_Network_Pharmacology_and_Experimental_Validation_to_Elucidate_the_Mechanism_of_Jiegeng_Decoction_in_Improving_Allergic_Asthma/24754951

الاتاحة: https://doi.org/10.1021/acsomega.3c06914.s001
https://figshare.com/articles/journal_contribution/Integrating_Network_Pharmacology_and_Experimental_Validation_to_Elucidate_the_Mechanism_of_Jiegeng_Decoction_in_Improving_Allergic_Asthma/24754951