يعرض 1 - 10 نتائج من 10 نتيجة بحث عن '"Terwesten, Felix"', وقت الاستعلام: 0.37s تنقيح النتائج
  1. 1
    Academic Journal
    Identification and in silico structural analysis of Gallus gallus protein arginine methyltransferase 4 ( PRMT4)

    المؤلفون: Berberich, Hannah, Terwesten, Felix, Rakow, Sinja, Sahu, Peeyush, Bouchard, Caroline, Meixner, Marion, Philipsen, Sjaak, Kolb, Peter, Bauer, Uta‐Maria

    المساهمون: Deutsche Forschungsgemeinschaft, José Carreras Leukämie-Stiftung, Landsteiner Foundation for Blood Transfusion Research

    المصدر: FEBS Open Bio ; volume 7, issue 12, page 1909-1923 ; ISSN 2211-5463 2211-5463

    الاتاحة: http://dx.doi.org/10.1002/2211-5463.12323
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F2211-5463.12323
    https://febs.onlinelibrary.wiley.com/doi/pdf/10.1002/2211-5463.12323

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  2. 2
    Academic Journal
    Targeting a Cryptic Pocket in a Protein–Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface

    المؤلفون: Nguyen, Dzung, Xie, Xiulan, Jakobi, Stephan, Terwesten, Felix, Metz, Alexander, Nguyen, T. X. Phong, Palchykov, Vitalii A., Heine, Andreas, Reuter, Klaus, Klebe, Gerhard

    المصدر: ACS chemical biology 16(6), 1090 - 1098 (2021). doi:10.1021/acschembio.1c00296

    مصطلحات موضوعية: info:eu-repo/classification/ddc/540

    جغرافية الموضوع: DE

    Relation: info:eu-repo/semantics/altIdentifier/issn/1554-8929; info:eu-repo/semantics/altIdentifier/issn/1554-8937; info:eu-repo/semantics/altIdentifier/pmid/pmid:34081441; info:eu-repo/semantics/altIdentifier/wos/WOS:000664331200015; https://bib-pubdb1.desy.de/record/459888; https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-02807%22

    الاتاحة: https://bib-pubdb1.desy.de/record/459888
    https://bib-pubdb1.desy.de/search?p=id:%22PUBDB-2021-02807%22

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  3. 3
    Academic Journal
    Identification of a novel polyfluorinated compound as a lead to inhibit human enzymes aldose reductase and AKR1B10 : structure determination of both ternary complexes and implications for drug design

    المؤلفون: Cousido-Siah, Alexandra, Ruiz, Francesc X., Mitschler, André, Porte Orduna, Sergio, De Lera, Ángel R., Martín, María J., Manzanaro, Sonia, de la Fuente, Jesús A., Terwesten, Felix, Betz, Michael, Klebe, Gerhard, Farrés, Jaume, Parés i Casasampera, Xavier, Podjarny, Alberto

    مصطلحات موضوعية: Aldo-keto reductases, Aldose reductase, AKR1B10, Inhibitors

    وصف الملف: application/pdf

    Relation: Acta crystallographica. Section D, Biological crystallography; Vol. 70 (December 2014), p. 889-903; https://ddd.uab.cat/record/181829; urn:10.1107/S1399004713033452; urn:oai:ddd.uab.cat:181829; urn:recercauab:ARE-75112; urn:articleid:13990047v70p889; urn:scopus_id:84896783721; urn:wos_id:000332406600027; urn:altmetric_id:2151344; urn:oai:egreta.uab.cat:publications/7021b06c-865a-4a12-9cb6-8ab27af65f74

    الاتاحة: https://ddd.uab.cat/record/181829

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  4. 4
    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

    المؤلفون: Terwesten, Felix, Klebe, Gerhard (Prof. Dr.)

    مصطلحات موضوعية: Protein-Arginin-Methyltransferasen, homology modeling, transient binding pockets, Chemie, tRNA-Guanin Transglykosylase, Chemistry and allied sciences, Aldo-Keto-Reduktasen, transiente Bindungstas, ddc:540, Aldosereduktase, structure-based drug design, cryptic binding sites, Shigella, PRMTs, TGT, computer-aided drug design, PRMTs, Aldo-Keto-Reduktasen, homology modeling, transient binding pockets

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a4a1de5d0f89c6df8a534fea8f8959

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  5. 5
    Academic Journal
    Price for Opening the Transient Specificity Pocket in Human Aldose Reductase upon Ligand Binding: Structural, Thermodynamic, Kinetic, and Computational Analysis

    المؤلفون: Rechlin, Chris, Scheer, Frithjof, Terwesten, Felix, Wulsdorf, Tobias, Pol, Ewa, Fridh, Veronica, Toth, Philipp, Diederich, Wibke E., Heine, Andreas, Klebe, Gerhard

    المساهمون: H2020 European Research Council

    المصدر: ACS Chemical Biology ; volume 12, issue 5, page 1397-1415 ; ISSN 1554-8929 1554-8937

    الاتاحة: http://dx.doi.org/10.1021/acschembio.7b00062
    https://pubs.acs.org/doi/pdf/10.1021/acschembio.7b00062

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  6. 6
    Academic Journal
    High resolution crystal structure of Clostridium propionicumβ-alanyl-CoA:ammonia lyase, a new member of the “hot dog fold” protein superfamily ; Crystal Structure of Acl

    المؤلفون: Heine, Andreas, Herrmann, Gloria, Selmer, Thorsten, Terwesten, Felix, Buckel, Wolfgang, Reuter, Klaus

    المساهمون: Helmholz-Zentrum Berlin

    المصدر: Proteins: Structure, Function, and Bioinformatics ; volume 82, issue 9, page 2041-2053 ; ISSN 0887-3585

    الاتاحة: http://dx.doi.org/10.1002/prot.24557
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fprot.24557
    http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.24557/fullpdf

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  7. 7
    Academic Journal
    Ligand Binding Stepwise Disrupts Water Network in Thrombin: Enthalpic and Entropic Changes Reveal Classical Hydrophobic Effect

    المؤلفون: Biela, Adam, Sielaff, Frank, Terwesten, Felix, Heine, Andreas, Steinmetzer, Torsten, Klebe, Gerhard

    المصدر: Journal of Medicinal Chemistry ; volume 55, issue 13, page 6094-6110 ; ISSN 0022-2623 1520-4804

    الاتاحة: http://dx.doi.org/10.1021/jm300337q
    https://pubs.acs.org/doi/pdf/10.1021/jm300337q

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  8. 8
    Academic Journal
    High resolution crystal structure of Clostridium propionicum β-alanyl-CoA:ammonia lyase, a new member of the 'hot dog fold' protein superfamily.

    المؤلفون: Heine, Andreas, Herrmann, Gloria, Selmer, Thorsten, Terwesten, Felix, Buckel, Wolfgang, Reuter, Klaus

    المصدر: Proteins; Sep2014, Vol. 82 Issue 9, p2041-2053, 13p


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  9. 9
    Academic Journal
    Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.

    المؤلفون: Cousido-Siah, Alexandra, Ruiz, Francesc X., Mitschler, André, Porté, Sergio, de Lera, Ángel R., Martín, María J., Manzanaro, Sonia, de la Fuente, Jesús A., Terwesten, Felix, Betz, Michael, Klebe, Gerhard, Farrés, Jaume, Parés, Xavier, Podjarny, Alberto Podjarny

    المصدر: Acta Crystallographica: Section D (Wiley-Blackwell); Mar2014, Vol. 70 Issue 3, p889-903, 15p

    مصطلحات موضوعية: ALDOSE reductase, DRUG design, FLUORINATION, DIABETES complications, GENETIC mutation


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  10. 10
    Academic Journal
    Ligand Binding StepwiseDisrupts Water Network inThrombin: Enthalpic and Entropic Changes Reveal Classical HydrophobicEffect.

    المؤلفون: Biela, Adam, Sielaff, Frank, Terwesten, Felix, Heine, Andreas, Steinmetzer, Torsten, Klebe, Gerhard

    المصدر: Journal of Medicinal Chemistry; Jul2012, Vol. 55 Issue 13, p6094-6110, 17p


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