المؤلفون: Andresa Heemann Betti, John Gerry Kenna, Terry R. Van Vleet, Palanisamy Aruselvan, Liz Girardi Müller

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: preclinical assays, drug discovery, toxicity, in vitro, in vivo, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1225806/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/3552e2ba5aa84c33985431f55c5232f7

المؤلفون: Caitlin Krause, Kinga Suwada, Eric A. G. Blomme, Kenneth Kowalkowski, Michael J. Liguori, Prathap Kumar Mahalingaiah, Scott Mittelstadt, Richard Peterson, Lauren Rendino, Andy Vo, Terry R. Van Vleet

المصدر: Frontiers in Genetics, Vol 13 (2023)

مصطلحات موضوعية: transcript, RNAseq, gene, pre-clinical, tissue, atlas, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.1078050/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/7881aa456498428f9b206c7a58d855ee

المؤلفون: Mohan S. Rao, Terry R. Van Vleet, Rita Ciurlionis, Wayne R. Buck, Scott W. Mittelstadt, Eric A. G. Blomme, Michael J. Liguori

المصدر: Frontiers in Genetics, Vol 9 (2019)

مصطلحات موضوعية: RNA-Seq, microarray, toxicogenomics, liver toxicity, DEG, non-coding transcripts, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2018.00636/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/8f54e5a06be041a38c8aef764788a34c

المؤلفون: Subham Dasgupta, Tatiana Sharapova, Prathap Kumar Mahalingaiah, Brian N. Chorley, Ahmed Shoieb, Takayuki Tsuji, Alef dos Santos, Rohit Chari, Ali Ebrahimi, Deidre A. Dalmas Wilk, Syril Pettit, Bhupinder Bawa, Erin Vaughan, Terry R. Van Vleet, Constance A. Mitchell, Peter S.T. Yuen

مصطلحات موضوعية: Toxicology (incl. clinical toxicology), nephrotoxicity, miRNAs, urinary biomarkers, Kidney

Relation: https://figshare.com/articles/poster/Urinary_MicroRNA_Biomarkers_of_Drug-induced_Kidney_Injury_DIKI_Demonstrate_Differences_in_Sensitivity_within_Exosomal_Fraction_Compared_to_Whole_Urine/25565628

الاتاحة: https://doi.org/10.23645/epacomptox.25565628.v1
https://figshare.com/articles/poster/Urinary_MicroRNA_Biomarkers_of_Drug-induced_Kidney_Injury_DIKI_Demonstrate_Differences_in_Sensitivity_within_Exosomal_Fraction_Compared_to_Whole_Urine/25565628

المؤلفون: Caitlin Krause, Kinga Suwada, Eric A. G. Blomme, Kenneth Kowalkowski, Michael J. Liguori, Prathap Kumar Mahalingaiah, Scott Mittelstadt, Richard Peterson, Lauren Rendino, Andy Vo, Terry R. Van Vleet

مصطلحات موضوعية: Genetics, Genetic Engineering, Biomarkers, Developmental Genetics (incl. Sex Determination), Epigenetics (incl. Genome Methylation and Epigenomics), Gene Expression (incl. Microarray and other genome-wide approaches), Genome Structure and Regulation, Genomics, Genetically Modified Animals, Livestock Cloning, Gene and Molecular Therapy, transcript, RNAseq, gene, pre-clinical, tissue, atlas

Relation: https://figshare.com/articles/dataset/DataSheet3_Preclinical_species_gene_expression_database_Development_and_meta-analysis_csv/21908088

الاتاحة: https://doi.org/10.3389/fgene.2022.1078050.s003
https://figshare.com/articles/dataset/DataSheet3_Preclinical_species_gene_expression_database_Development_and_meta-analysis_csv/21908088

المؤلفون: Caitlin Krause, Kinga Suwada, Eric A. G. Blomme, Kenneth Kowalkowski, Michael J. Liguori, Prathap Kumar Mahalingaiah, Scott Mittelstadt, Richard Peterson, Lauren Rendino, Andy Vo, Terry R. Van Vleet

مصطلحات موضوعية: Genetics, Genetic Engineering, Biomarkers, Developmental Genetics (incl. Sex Determination), Epigenetics (incl. Genome Methylation and Epigenomics), Gene Expression (incl. Microarray and other genome-wide approaches), Genome Structure and Regulation, Genomics, Genetically Modified Animals, Livestock Cloning, Gene and Molecular Therapy, transcript, RNAseq, gene, pre-clinical, tissue, atlas

Relation: https://figshare.com/articles/figure/Image4_Preclinical_species_gene_expression_database_Development_and_meta-analysis_TIF/21908103

الاتاحة: https://doi.org/10.3389/fgene.2022.1078050.s008
https://figshare.com/articles/figure/Image4_Preclinical_species_gene_expression_database_Development_and_meta-analysis_TIF/21908103

المؤلفون: Caitlin Krause, Kinga Suwada, Eric A. G. Blomme, Kenneth Kowalkowski, Michael J. Liguori, Prathap Kumar Mahalingaiah, Scott Mittelstadt, Richard Peterson, Lauren Rendino, Andy Vo, Terry R. Van Vleet

مصطلحات موضوعية: Genetics, Genetic Engineering, Biomarkers, Developmental Genetics (incl. Sex Determination), Epigenetics (incl. Genome Methylation and Epigenomics), Gene Expression (incl. Microarray and other genome-wide approaches), Genome Structure and Regulation, Genomics, Genetically Modified Animals, Livestock Cloning, Gene and Molecular Therapy, transcript, RNAseq, gene, pre-clinical, tissue, atlas

Relation: https://figshare.com/articles/dataset/Table1_Preclinical_species_gene_expression_database_Development_and_meta-analysis_docx/21908118

الاتاحة: https://doi.org/10.3389/fgene.2022.1078050.s013
https://figshare.com/articles/dataset/Table1_Preclinical_species_gene_expression_database_Development_and_meta-analysis_docx/21908118

المؤلفون: Yevgeniya E. Koshman, Aimee L. Bielinski, Brandan M. Bird, Jonathon R. Green, Kenneth L. Kowalkowski, Jie Lai-Zhang, Prathap Kumar Mahalingaiah, James W. Sawicki, Nari N. Talaty, Amanda S. Wilsey, Mark T. Zafiratos, Terry R. Van Vleet

المصدر: Journal of Pharmacological and Toxicological Methods. 120:107251

مصطلحات موضوعية: Pharmacology, History, Polymers and Plastics, Business and International Management, Toxicology, Industrial and Manufacturing Engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cbf38cc7da899544306ac579064f8c
https://doi.org/10.1016/j.vascn.2023.107251

المؤلفون: William R Proctor, Sherry Ralston, Szczepan W Baran, Gorm Yoder, Brian R. Berridge, Kristin Fabre, Yvonne Will, Terry R. Van Vleet

المصدر: Lab on a Chip. 20:1049-1057

مصطلحات موضوعية: Drug, Drug disposition, business.industry, media_common.quotation_subject, Biomedical Engineering, Bioengineering, General Chemistry, Kidney, Biochemistry, Animal data, Liver, Pharmaceutical Preparations, Risk analysis (engineering), Blood-Brain Barrier, Organ specific, Animals, Humans, Medicine, Tissue specific, Human safety, business, Lung, Pharmaceutical industry, media_common, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076b0fe9f6741c5106bc32ac5fb4e1c2
https://doi.org/10.1039/c9lc01168d

المؤلفون: Jean-Charles Gautier, Myrtle Davis, Douglas A. Keller, Niresh Hariparsad, Jonathan A. Phillips, Radhakrishna Sura, Taraka Sai Pavan Grandhi, Terry R. Van Vleet

المصدر: Lab on a Chip. 20:468-476

مصطلحات موضوعية: 0301 basic medicine, Drug Industry, Drug Evaluation, Preclinical, Biomedical Engineering, Bioengineering, Kidney, Models, Biological, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Development, Lab-On-A-Chip Devices, Humans, Safety testing, Pharmaceutical industry, ADME, urogenital system, business.industry, Human kidney, General Chemistry, Microfluidic Analytical Techniques, 030104 developmental biology, Pharmaceutical Preparations, Drug development, Risk analysis (engineering), 030220 oncology & carcinogenesis, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de840a616151794554b2a7cfe1beb0ca
https://doi.org/10.1039/c9lc00925f

المؤلفون: Prathap Kumar S. Mahalingaiah, Rita Ciurlionis, Bhupinder Bawa, Michael J. Liguori, Terry R. Van Vleet, Binu K. Philip, Kenneth R. Durbin, Ronnie L. Yeager, Srinivasa R. Mantena, Brian P. Enright

المصدر: Pharmacology & Therapeutics. 200:110-125

مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, medicine.drug_class, Endocytosis, Monoclonal antibody, 03 medical and health sciences, 0302 clinical medicine, Therapeutic index, Antigen, medicine, Animals, Humans, Pharmacology (medical), Cytotoxicity, Pharmacology, biology, Chemistry, Biological Transport, body regions, 030104 developmental biology, 030220 oncology & carcinogenesis, Toxicity, Cancer cell, Cancer research, biology.protein, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275e67fbf57becdf447bb218d67a52af
https://doi.org/10.1016/j.pharmthera.2019.04.008

المؤلفون: Michael J. Liguori, James J. Lynch, Mohan S. Rao, Terry R. Van Vleet, Scott E. Warder

المصدر: SLAS Discovery. 24:1-24

مصطلحات موضوعية: 0301 basic medicine, Critical gap, Process (engineering), Computer science, Liability, Drug Evaluation, Preclinical, Computational toxicology, Biochemistry, Analytical Chemistry, Small Molecule Libraries, 03 medical and health sciences, Identification (information), 030104 developmental biology, 0302 clinical medicine, Risk analysis (engineering), 030220 oncology & carcinogenesis, Informatics, Drug Discovery, Animals, Humans, Molecular Medicine, Computer Simulation, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300a8a3a4b51b7269f693c79518ba79b
https://doi.org/10.1177/2472555218799713

المؤلفون: Junguo Zhou, Paul Butler, Meredith Crosby, Laura Aschenbrenner, Jim Blank, Jonathan G. Moggs, Vincent L. Reynolds, Kyle L. Kolaja, Derek D. Best, Dana Shuey, Matthew M. Abernathy, Terry R. Van Vleet, Chelsea Snyder, Patricia A. Escobar, Timothy K. Hart, Laura Custer

المصدر: Regulatory toxicology and pharmacology : RTP. 117

مصطلحات موضوعية: medicine.medical_specialty, Drug Industry, Drug-Related Side Effects and Adverse Reactions, Drug Evaluation, Preclinical, 010501 environmental sciences, Toxicology, 030226 pharmacology & pharmacy, 01 natural sciences, Risk Assessment, Epigenesis, Genetic, 03 medical and health sciences, 0302 clinical medicine, Transgenerational epigenetics, Surveys and Questionnaires, medicine, Animals, Humans, Epigenetics, Intensive care medicine, 0105 earth and related environmental sciences, business.industry, Safety pharmacology, Perspective (graphical), Nonclinical safety, General Medicine, Drug development, Pharmaceutical Preparations, Survey data collection, Drug and Narcotic Control, Risk assessment, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0c03ba3f1ed7746ed6a53efdd5ecdd
https://pubmed.ncbi.nlm.nih.gov/32911461

المؤلفون: Scott W. Mittelstadt, Eric A.G. Blomme, James J. Lynch, Terry R. Van Vleet

المصدر: Journal of Pharmacological and Toxicological Methods. 87:108-126

مصطلحات موضوعية: Pharmacology, Databases, Factual, Drug-Related Side Effects and Adverse Reactions, Side effect, Drug discovery, Safety pharmacology, Drug Evaluation, Preclinical, Cardiovascular Agents, Biological activity, Scientific literature, Computational biology, Biology, Toxicology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Drug development, Drug Discovery, Cardiovascular agent, Animals, Humans, Adverse effect, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5881e7c79dd7e2fb949ecab44a5d3bd9
https://doi.org/10.1016/j.vascn.2017.02.020

المؤلفون: Douglas A. Keller, Brian R. Berridge, Ananthsrinivas Chakilam, Yvonne Will, Monicah A. Otieno, Kristin M. Fabre, David B. Duignan, Yvonne P. Dragan, Lorna Ewart, Terry R. Van Vleet, Danilo A. Tagle, Claire G. Jeong, Jinping Gan, Peggy Guzzie-Peck, Jonathan A. Phillips, Jeetu Eswaraka, Sonia M. de Morais, David E. Watson, Radhakrishna Sura, William R Proctor

المصدر: Experimental Biology and Medicine. 242:1579-1585

مصطلحات موضوعية: 0301 basic medicine, Knowledge management, Drug Industry, business.industry, End user, Microfluidics, Liability, Drug Evaluation, Preclinical, Context (language use), General Biochemistry, Genetics and Molecular Biology, Biotechnology, 03 medical and health sciences, 030104 developmental biology, Resource (project management), Lab-On-A-Chip Devices, Paradigm shift, General partnership, Microchip Analytical Procedures, Commentary, Humans, business, Pace, Pharmaceutical industry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3128a14f0b4ce35a220ee4e7ecd5eeff
https://doi.org/10.1177/1535370217715441

المؤلفون: Anthony Lee, Eric A.G. Blomme, Hong Liu, Terry R. Van Vleet

المصدر: Toxicology Letters. 272:1-7

مصطلحات موضوعية: 0301 basic medicine, Drug, Acylation, media_common.quotation_subject, Metabolite, Carboxylic acid, Acyl glucuronidation, Toxicology, Models, Biological, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, Glucuronides, 0302 clinical medicine, Pharmacokinetics, Humans, media_common, chemistry.chemical_classification, Chemistry, General Medicine, Glutathione, 030104 developmental biology, Pharmaceutical Preparations, Biochemistry, Microsomes, Liver, lipids (amino acids, peptides, and proteins), Safety, Macromolecule

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38769350dd7562351cc57efd116b81b2
https://doi.org/10.1016/j.toxlet.2017.03.003

المؤلفون: Terry R Van Vleet, Rick G Schnellmann

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://medlib.yu.ac.kr/eur_j_oph/sem_nephrol/sem_n_pdf/SemNep_23_5_500.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1044.7848; http://medlib.yu.ac.kr/eur_j_oph/sem_nephrol/sem_n_pdf/SemNep_23_5_500.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1044.7848
http://medlib.yu.ac.kr/eur_j_oph/sem_nephrol/sem_n_pdf/SemNep_23_5_500.pdf

المؤلفون: Adrian Roth, Douglas A. Keller, Philip Hewitt, Andreas Baudy, Terry R. Van Vleet, Radhakrishna Sura, Monicah A. Otieno, Jinping Gan, William R Proctor

المصدر: Lab on a chip. 20(2)

مصطلحات موضوعية: Drug Industry, Process (engineering), Computer science, Biomedical Engineering, Drug Evaluation, Preclinical, Bioengineering, Biochemistry, Risk Assessment, 03 medical and health sciences, 0302 clinical medicine, Lab-On-A-Chip Devices, Animals, Humans, Animal testing, 030304 developmental biology, Pharmaceutical industry, 0303 health sciences, System development, business.industry, End user, General Chemistry, Drug development, Risk analysis (engineering), Safety risk, Liver, Pharmaceutical Preparations, 030220 oncology & carcinogenesis, Risk assessment, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad20b0de1b57f15d2012f4870b6fafb
https://pubmed.ncbi.nlm.nih.gov/31799979

المؤلفون: Terry R. Van Vleet, Mohan S. Rao, Andy H. Vo, Michael J. Liguori, Rishi R Gupta

المصدر: Chemical research in toxicology. 33(1)

مصطلحات موضوعية: Big Data, Quantitative structure–activity relationship, Drug-Related Side Effects and Adverse Reactions, Computer science, Process (engineering), Big data, Quantitative Structure-Activity Relationship, 010501 environmental sciences, Toxicology, Machine learning, computer.software_genre, 01 natural sciences, Machine Learning, 03 medical and health sciences, Animals, Humans, Drug toxicity, 030304 developmental biology, 0105 earth and related environmental sciences, 0303 health sciences, business.industry, General Medicine, Drug development, Toxicity, Artificial intelligence, Toxicogenomics, business, computer, Predictive modelling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c1fa6c278aca6133e53c1580a64247
https://pubmed.ncbi.nlm.nih.gov/31625725

المؤلفون: Scott W. Mittelstadt, Eric A. G. Blomme, Mufeng Hu, Srinivasa R. Mantena, Mohan S. Rao, Xin Huang, Terry R. Van Vleet, Rishi R Gupta, Michael J. Liguori

المصدر: Frontiers in Big Data

مصطلحات موضوعية: Drug, Big Data, Training set, Drug discovery, media_common.quotation_subject, secondary pharmacology, Computational biology, Biology, pocket search, Small molecule, Off-targets, Off targets, machine learning, Artificial Intelligence, In vivo, Proteome, Computer Science (miscellaneous), gene expression, Repurposing, Information Systems, media_common, Original Research, toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ae2ac5bd03530d200ed210bd9ad037
http://europepmc.org/articles/PMC7931946