المؤلفون: Shabalala, Simangele NE¹ (AUTHOR) 221072879@stu.ukzn.ac.za, Luvuno, M.¹ (AUTHOR), Mabandla, M.V.¹ (AUTHOR)

المصدر: Neuroscience. Dec2024, Vol. 562, p209-216. 8p.

مصطلحات موضوعية: *PREFRONTAL cortex, *TENOFOVIR, *DOPAMINE agents, *CEREBELLUM, *TREATMENT effectiveness

المؤلفون: Patel, Nimish¹ (AUTHOR) nipatel@health.ucsd.edu, Morris, Sheldon^2,3 (AUTHOR), Burke, Leah³ (AUTHOR), Chow, Karen³ (AUTHOR), Pacheco, Deedee³ (AUTHOR), Anderson, Peter⁴ (AUTHOR), Stancyzk, Frank⁵ (AUTHOR), Blumenthal, Jill^2,3 (AUTHOR)

المصدر: British Journal of Clinical Pharmacology. Oct2024, Vol. 90 Issue 10, p2360-2365. 6p.

مصطلحات موضوعية: *TRANSGENDER people, *EMTRICITABINE-tenofovir, *HORMONE therapy, *TENOFOVIR, *BLOOD sampling

المصدر: A Phase 2/3, Multicenter, Open-label, Multicohort Study Evaluating Pharmacokinetics (PK), Safety, and Efficacy of Cobicistat-boosted Atazanavir (ATV/co) or Cobicistat-boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in HIV-1 Infected, Virologically Suppressed Pediatric Participants

المصدر: Phase 3b, Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy

المصدر: A Phase 2, Open-label, Multicenter, Randomized Study to Evaluate the Persistence, Safety, Acceptability, and Pharmacokinetics of Twice Yearly Long-acting Subcutaneous Lenacapavir for HIV Pre-Exposure Prophylaxis (PrEP) in People Who Would Benefit From PrEP

المصدر: An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination With GS-4182 Versus Biktarvy in Treatment-Naive People With HIV-1

المؤلفون: National Institute of Allergy and Infectious Diseases (NIAID)

المصدر: A Phase I Trial for the Evaluation of the Two-way Pharmacokinetic-pharmacodynamic (PD) Interaction of Gender Affirming Exogenous Estrogen (With Testosterone Suppression) on TDF/FTC PrEP in Transgender Women (TGW)

المصدر: A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of Oral Islatravir Once-Monthly as Preexposure Prophylaxis in Cisgender Men and Transgender Women Who Have Sex With Men, and Are at High Risk for HIV-1 Infection

Other URLs: http://engagezone.msd.com/ds_documentation.php

المصدر: An Operationally Seamless Phase 2/3, Randomized, Active-Controlled Study Evaluating the Safety and Efficacy of an Oral Weekly Regimen of GS-1720 in Combination With GS-4182 Versus Biktarvy in Virologically Suppressed People With HIV-1

المؤلفون: HIV Prevention Trials Network, National Institute on Drug Abuse (NIDA), National Institute of Allergy and Infectious Diseases (NIAID)

المصدر: A Phase 2, Open-Label, Multicenter, Randomized Study to Evaluate the Pharmacokinetics and Safety of Twice Yearly Long-Acting Subcutaneous Lenacapavir for Pre-Exposure Prophylaxis in People Who Inject Drugs

المؤلفون: Landovitz, Raphael J, Tao, Li, Yang, Juan, de Boer, Melanie, Carter, Christoph, Das, Moupali, Baeten, Jared M, Liu, Albert, Hoover, Karen W, Celum, Connie, Grinsztejn, Beatriz, Morris, Sheldon, Wheeler, Darrell P, Mayer, Kenneth H, Golub, Sarit A, Bekker, Linda-Gail, Diabaté, Souleymane, Hoornenborg, Elske, Myers, Janet, Leech, Ashley A, McCormack, Sheena, Chan, Philip A, Sweat, Michael, Matthews, Lynn T, Grant, Robert, Beyrer, Chris, Brown, Joelle, Clark, Jesse, Colson, Paul, Eakle, Robyn, Farley, Jason, Flash, Charlene A, Gallardo, Jorge, Gottlieb, Geoffrey, Grangeiro, Alexandre, Heffron, Renee, Hosek, Sybil, Hull, Mark, Idoko, John, Inwani, Irene, Koenig, Helen, Kurth, Ann, Lee, Shui-shan, Mayer, Kenneth, Mboup, Souleymane, Meyer, Jaimie, Mills, Anthony, Mujugira, Andrew, Pala, Pietro, Phoenix, John, Piatt, Janice, Russell, Darren, Sanders, Eduard, Scott, Rachel, Sevelius, Jae, Shang, Hong, Siegel, Marc, Swaminathan, Shobha, Tamayo, Vivian, Tan, Darrell, Taylor, Allan, Vuylsteke, Bea

المصدر: Clinical Infectious Diseases. 79(5)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Infectious Diseases, Health Disparities, Clinical Trials and Supportive Activities, Sexually Transmitted Infections, Clinical Research, HIV/AIDS, Prevention, Women's Health, Infection, Good Health and Well Being, Humans, HIV Infections, HIV-1, Male, Female, Incidence, Anti-HIV Agents, Pre-Exposure Prophylaxis, Adult, Drug Resistance, Viral, Medication Adherence, Prospective Studies, Middle Aged, Tenofovir, Emtricitabine, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination, Young Adult, pre-exposure prophylaxis, emtricitabine, tenofovir disoproxil fumarate, Global F/TDF PrEP Study Team, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9j09602b
https://escholarship.org/content/qt9j09602b/qt9j09602b.pdf

المؤلفون: Pan, Calvin Q^1,2, Zhu, Lin³, Yu, Andy S⁴, Zhao, Yuchan⁵, Zhu, Bo⁶ daieh2008@126.com, Dai, Erhei⁵ daieh2008@126.com

المصدر: Clinical Infectious Diseases. 10/15/2024, Vol. 79 Issue 4, p953-964. 12p.

مصطلحات موضوعية: *RESEARCH funding, *TENOFOVIR, *CHRONIC hepatitis B, *META-analysis, *DESCRIPTIVE statistics, *ANTIVIRAL agents, *SYSTEMATIC reviews, *VERTICAL transmission (Communicable diseases), *CONFIDENCE intervals, *INFECTIOUS disease transmission, *PHARMACODYNAMICS, *PREGNANCY

المصدر: A Phase 2 Randomized Cross-Over Design Study of the Early Metabolic Effects of Dolutegravir or Tenofovir Alafenamide in Healthy Volunteers
Squires K, Kityo C, Hodder S, Johnson M, Voronin E, Hagins D, Avihingsanon A, Koenig E, Jiang S, White K, Cheng A, Szwarcberg J, Cao H. Integrase inhibitor versus protease inhibitor based regimen for HIV-1 infected women (WAVES): a randomised, controlled, double-blind, phase 3 study. Lancet HIV. 2016 Sep;3(9):e410-e420. doi: 10.1016/S2352-3018(16)30016-9. Epub 2016 May 27.
Molina JM, Clotet B, van Lunzen J, Lazzarin A, Cavassini M, Henry K, Kulagin V, Givens N, de Oliveira CF, Brennan C; FLAMINGO study team. Once-daily dolutegravir versus darunavir plus ritonavir for treatment-naive adults with HIV-1 infection (FLAMINGO): 96 week results from a randomised, open-label, phase 3b study. Lancet HIV. 2015 Apr;2(4):e127-36. doi: 10.1016/S2352-3018(15)00027-2. Epub 2015 Mar 10. Erratum In: Lancet HIV. 2015 Apr;2(4):e126.
Lennox JL, Landovitz RJ, Ribaudo HJ, Ofotokun I, Na LH, Godfrey C, Kuritzkes DR, Sagar M, Brown TT, Cohn SE, McComsey GA, Aweeka F, Fichtenbaum CJ, Presti RM, Koletar SL, Haas DW, Patterson KB, Benson CA, Baugh BP, Leavitt RY, Rooney JF, Seekins D, Currier JS; ACTG A5257 Team. Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial. Ann Intern Med. 2014 Oct 7;161(7):461-71. doi: 10.7326/M14-1084. Erratum In: Ann Intern Med. 2014 Nov 4;161(9):680.

المؤلفون: Code Pharma

المساهمون: Ricardo Sobhie Diaz, Professor

المصدر: Clinical Study to Evaluate the Efficacy and Safety of Gammora® in Addition to Standard Antiretroviral Treatment for HIV Infection in Antiretroviral Treatment-Naïve Participants
Levin A, Hayouka Z, Friedler A, Loyter A. Specific eradication of HIV-1 from infected cultured cells. AIDS Res Ther. 2010 Aug 19;7:31. doi: 10.1186/1742-6405-7-31.
Levin A, Hayouka Z, Helfer M, Brack-Werner R, Friedler A, Loyter A. Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration. PLoS One. 2009;4(1):e4155. doi: 10.1371/journal.pone.0004155. Epub 2009 Jan 7.
Levin A, Hayouka Z, Helfer M, Brack-Werner R, Friedler A, Loyter A. Stimulation of the HIV-1 integrase enzymatic activity and cDNA integration by a peptide derived from the integrase protein. Biopolymers. 2010 Aug;93(8):740-51. doi: 10.1002/bip.21469.
Rizza SA, Badley AD. HIV protease inhibitors impact on apoptosis. Med Chem. 2008 Jan;4(1):75-9. doi: 10.2174/157340608783331443.

المصدر: Prospective Study on the Incidence of Hepatitis B Virus Reactivation in Untreated Patients With Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide
Picardi M, Giordano C, Della Pepa R, Pugliese N, Leone A, Delle Cave G, Iula R, Pane F, Gentile G. Regarding "Hepatitis B Surface Antigen Positivity Is an Independent Unfavorable Prognostic Factor in Diffuse Large B-Cell Lymphoma in the Rituximab Era". Oncologist. 2021 Jun;26(6):e1083-e1084. doi: 10.1002/onco.13710. Epub 2021 Feb 24.

المؤلفون: National Institute of Allergy and Infectious Diseases (NIAID), Centre for the AIDS Programme of Research in South Africa

المساهمون: Paul Drain, Associate Professor

المصدر: Simplifying Treatment and Monitoring for HIV (STREAM HIV): Point-of-Care Urine Tenofovir Adherence and Viral Load Testing to Improve HIV Outcomes in South Africa
Bardon AR, Dorward J, Sookrajh Y, Sayed F, Quame-Amaglo J, Pillay C, Feutz E, Ngobese H, Simoni JM, Sharma M, Cressey TR, Gandhi M, Lessells R, Moodley P, Naicker N, Naidoo K, Thomas K, Celum C, Abdool Karim S, Garrett N, Drain PK. Simplifying TREAtment and Monitoring for HIV (STREAM HIV): protocol for a randomised controlled trial of point-of-care urine tenofovir and viral load testing to improve HIV outcomes. BMJ Open. 2021 Oct 5;11(10):e050116. doi: 10.1136/bmjopen-2021-050116.

المصدر: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-Controlled Study With Deferred Active Treatment to Investigate the Efficacy, Safety, and Pharmacokinetics of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

Other URLs: https://www.janssen.com/clinical-trials/transparency

المصدر: A Phase 2, Randomized, Open-label, Multicenter Study to Evaluate Efficacy, Pharmacokinetics, Safety, and Tolerability of Treatment With JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog With or Without JNJ-56136379 in Treatment-naive Patients With HBeAg Positive Chronic Hepatitis B Virus Infection

Other URLs: https://www.janssen.com/clinical-trials/transparency

المؤلفون: ViiV Healthcare

المصدر: Dolutegravir Plus Lamivudine (DTG/3TC) Dual Therapy Versus Dolutegravir With TDF-lamivudine (DTG + TDF/3TC) Among Antiretroviral naïve People With HIV and TB Receiving Rifampin-based TB Treatment

المصدر: Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males - A Sub-study of HPTN 083