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المؤلفون: Ann K. Wright, Maria Lindfors, Martin Hermansson, Aino-Liisa Mutka, Reijo Käkelä, Aleksi Haapanen, Thomas H. Gillingwater, Elina Ikonen, Anne Rokka, Jaana Tyynelä, Matti Jauhiainen, Garry L. Corthals, Teija Inkinen
المصدر: Mutka, A-L, Haapanen, A, Kakela, R, Lindfors, M, Wright, A K, Inkinen, T, Hermansson, M, Rokka, A, Corthals, G, Jauhiainen, M, Gillingwater, T H, Ikonen, E & Tyynela, J 2010, ' Murine cathepsin D deficiency is associated with dysmyelination/myelin disruption and accumulation of cholesteryl esters in the brain ', Journal of Neurochemistry, vol. 112, no. 1, pp. 193-203 . https://doi.org/10.1111/j.1471-4159.2009.06440.x
مصطلحات موضوعية: Apolipoprotein E, medicine.medical_specialty, Proteolipid protein 1, mouse model, cathepsin D, Biological Transport, Active, Cathepsin D, Biochemistry, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Myelin, proteomics, 0302 clinical medicine, Internal medicine, medicine, Animals, Myelin Sheath, 030304 developmental biology, Mice, Knockout, 0303 health sciences, biology, Brain, Lipid metabolism, medicine.disease, ultrastructure, Myelin basic protein, Mice, Inbred C57BL, myelin, medicine.anatomical_structure, Endocrinology, nervous system, Knockout mouse, biology.protein, lipidomics, lipids (amino acids, peptides, and proteins), Neuronal ceroid lipofuscinosis, Cholesterol Esters, 030217 neurology & neurosurgery, Demyelinating Diseases
وصف الملف: application/pdf
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المؤلفون: Noreen A. Alexander, Jaana Tyynelä, Thomas H. Gillingwater, Paul Saftig, Sanna Partanen, Catherine Kielar, Aleksi Haapanen, Teija Inkinen, Jonathan D. Cooper, Charles Pontikis
المصدر: ResearcherID
مصطلحات موضوعية: Thalamus, Cathepsin D, Nerve Tissue Proteins, Biology, Pathology and Forensic Medicine, Synapse, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Neuronal Ceroid-Lipofuscinoses, Neural Pathways, medicine, Animals, 030304 developmental biology, Neurons, 0303 health sciences, Cell Death, Neurodegeneration, Brain, Somatosensory Cortex, General Medicine, medicine.disease, Antigens, Differentiation, Congenital neuronal ceroid lipofuscinosis, Mice, Inbred C57BL, Disease Models, Animal, Gene Expression Regulation, Neurology, Ventral posterior nucleus, Synapses, Synaptophysin, biology.protein, Neuronal ceroid lipofuscinosis, Neurology (clinical), Atrophy, Neuroscience, 030217 neurology & neurosurgery