المؤلفون: Daines, C. L., Tullis, E., Costa, S., Linnemann, R. W., Mall, M. A., McKone, E. F., Polineni, D., Quon, B. S., Ringshausen, F. C., Rowe, S. M., Selvadurai, H., Taylor-Cousar, J. L., Withers, N. J., Ahluwalia, N., Moskowitz, S. M., Prieto-Centurion, V., Tan, Y. V., Tian, S., Weinstock, T., Xuan, F., Zhang, Y., Ramsey, B., Griese, M.

Relation: http://erj.ersjournals.com/cgi/pmidlookup?view=long&pmid=37945033; Daines CL, Tullis E, Costa S, Linnemann RW, Mall MA, McKone EF, et al. Long-Term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in People With Cystic Fibrosis and at Least One F508del Allele: 144-Week Interim Results From a 192-Week Open-label Extension Study. The European respiratory journal. 2023.; The European respiratory journal; https://hdl.handle.net/11287/623107

الاتاحة: https://hdl.handle.net/11287/623107
https://doi.org/10.1183/13993003.02029-2022

المؤلفون: Mayer-Hamblett, N., van Koningsbruggen-Rietschel, S., Nichols, D. P., VanDevanter, D. R., Davies, J. C., Lee, T., Durmowicz, A. G., Ratjen, F., Konstan, M. W., Pearson, K., Bell, S. C., Clancy, J. P., Taylor-Cousar, J. L., De Boeck, K., Donaldson, S. H., Downey, D. G., Flume, P. A., Drevinek, P., Goss, C. H., Fajac, I., Magaret, A. S., Quon, B. S., Singleton, S. M., VanDalfsen, J. M., Retsch-Bogart, G. Z.

المصدر: Mayer-Hamblett , N , van Koningsbruggen-Rietschel , S , Nichols , D P , VanDevanter , D R , Davies , J C , Lee , T , Durmowicz , A G , Ratjen , F , Konstan , M W , Pearson , K , Bell , S C , Clancy , J P , Taylor-Cousar , J L , De Boeck , K , Donaldson , S H , Downey , D G , Flume , P A , Drevinek , P , Goss , C H , Fajac , I , Magaret , A S , ....

مصطلحات موضوعية: Cystic Fibrosis/drug therapy, Cystic Fibrosis Transmembrane Conductance Regulator/drug effects, Drug Development/organization & administration, Humans, International Cooperation, /dk/atira/pure/subjectarea/asjc/2700/2735, name=Pediatrics, Perinatology, and Child Health, /dk/atira/pure/subjectarea/asjc/2700/2740, name=Pulmonary and Respiratory Medicine

وصف الملف: application/pdf

الاتاحة: https://pure.qub.ac.uk/en/publications/3a5f6ec7-62c0-4f6a-a670-535421685313
https://doi.org/10.1016/j.jcf.2020.05.011
https://pureadmin.qub.ac.uk/ws/files/212664320/Global_manuscript_2020_0518_clean.pdf

المؤلفون: Barry P. J., Mall M. A., Alvarez A., Colombo C., de Winter-De Groot K. M., Fajac I., McBennett K. A., McKone E. F., Ramsey B. W., Sutharsan S., Taylor-Cousar J. L., Tullis E., Ahluwalia N., Jun L. S., Moskowitz S. M., Prieto-Centurion V., Tian S., Waltz D., Xuan F., Zhang Y., Rowe S. M., Polineni D.

المساهمون: P.J. Barry, M.A. Mall, A. Alvarez, C. Colombo, K.M. de Winter-De Groot, I. Fajac, K.A. Mcbennett, E.F. Mckone, B.W. Ramsey, S. Sutharsan, J.L. Taylor-Cousar, E. Tulli, N. Ahluwalia, L.S. Jun, S.M. Moskowitz, V. Prieto-Centurion, S. Tian, D. Waltz, F. Xuan, Y. Zhang, S.M. Rowe, D. Polineni

مصطلحات موضوعية: adolescent, adult, aminophenol, benzodioxole, child, chloride channel agonist, chloride, cystic fibrosi, cystic fibrosis transmembrane conductance regulator, double-blind method, drug combination, female, genotype, human, indole, male, pyrazole, pyridine, quinoline, sweat, Settore MED/38 - Pediatria Generale e Specialistica

Relation: info:eu-repo/semantics/altIdentifier/pmid/34437784; info:eu-repo/semantics/altIdentifier/wos/WOS:000691300600010; volume:385; issue:9; firstpage:815; lastpage:825; numberofpages:11; journal:NEW ENGLAND JOURNAL OF MEDICINE; http://hdl.handle.net/2434/870175; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85114016110

الاتاحة: http://hdl.handle.net/2434/870175
https://doi.org/10.1056/NEJMoa2100665

المؤلفون: Nick, J A, Sanders, L A, Ickes, B, Briones, N J, Caceres, S M, Malcolm, K C, Brayshaw, S J, Chacon, C S, Barboa, C M, Jones, M C, St Clair, C, Taylor-Cousar, J L, Nichols, D P, Sagel, S D, Strand, M, Saavedra, M T

المصدر: Thorax ; volume 68, issue 10, page 929-937 ; ISSN 0040-6376 1468-3296

الاتاحة: http://dx.doi.org/10.1136/thoraxjnl-2012-202278
https://syndication.highwire.org/content/doi/10.1136/thoraxjnl-2012-202278

المؤلفون: Middleton P. G., Mall M. A., Drevinek P., Lands L. C., McKone E. F., Polineni D., Ramsey B. W., Taylor-Cousar J. L., Tullis E., Vermeulen F., Marigowda G., McKee C. M., Moskowitz S. M., Nair N., Savage J., Simard C., Tian S., Waltz D., Xuan F., Rowe S. M., Jain R., Magazzu G.

المساهمون: Middleton, P. G., Mall, M. A., Drevinek, P., Lands, L. C., McKone, E. F., Polineni, D., Ramsey, B. W., Taylor-Cousar, J. L., Tullis, E., Vermeulen, F., Marigowda, G., McKee, C. M., Moskowitz, S. M., Nair, N., Savage, J., Simard, C., Tian, S., Waltz, D., Xuan, F., Rowe, S. M., Jain, R., Magazzu, G.

مصطلحات موضوعية: Adolescent, Adult, Aminophenol, Benzodioxole, Child, Chloride Channel Agonist, Chloride, Cystic Fibrosi, Cystic Fibrosis Transmembrane Conductance Regulator, Double-Blind Method, Drug Combination, Female, Forced Expiratory Volume, Genotype, Human, Indole, Male, Pyrazole, Pyridine, Pyrrolidine, Quinolone, Sweat, Young Adult, Mutation

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/31697873; info:eu-repo/semantics/altIdentifier/wos/WOS:000496238300006; volume:381; issue:19; firstpage:1809; lastpage:1819; numberofpages:11; journal:NEW ENGLAND JOURNAL OF MEDICINE; http://hdl.handle.net/11570/3193372; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85074721693

الاتاحة: http://hdl.handle.net/11570/3193372
https://doi.org/10.1056/NEJMoa1908639
https://www.nejm.org/doi/pdf/10.1056/NEJMoa1908639?articleTools=true

المؤلفون: Middleton, P. G., Mall, M. A., Drevinek, P., Lands, L. C., Mckone, E. F., Polineni, D., Ramsey, B. W., Taylor-Cousar, J. L., Tullis, E., Vermeulen, F., Marigowda, G., Mckee, C. M., Moskowitz, S. M., Nair, N., Savage, J., Simard, C., Tian, S., Waltz, D., Xuan, F., Rowe, S. M., Jain, R., Magazzu, G.

المساهمون: Clinical sciences, Physiotherapy, Human Physiology and Anatomy, Pediatrics

المصدر: N Engl J Med

مصطلحات موضوعية: Male, Adolescent, Adult, Aminophenols, Benzodioxoles, Child, Chloride Channel Agonists, Chlorides, Cystic Fibrosis, Cystic Fibrosis Transmembrane Conductance Regulator, Double-Blind Method, Drug Combinations, Female, Forced Expiratory Volume, Genotype, Humans, Indoles, Pyrazoles, Pyridines, Pyrrolidines, Quinolones, Sweat, Young Adult, Mutation, 030204 cardiovascular system & hematology, medicine.disease_cause, Gastroenterology, Cystic fibrosis, Ivacaftor, chemistry.chemical_compound, 0302 clinical medicine, 030212 general & internal medicine, biology, Lumacaftor, General Medicine, Cystic fibrosis transmembrane conductance regulator, medicine.drug, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Article, 03 medical and health sciences, Internal medicine, medicine, Allele, business.industry, Potentiator, medicine.disease, chemistry, biology.protein, business

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510c67aeb22259df0e4b168446026ae1
http://hdl.handle.net/11570/3193372

المؤلفون: Taylor-Cousar, J. L., Derichs, N., Tullis, D. E., Davies, J. C., Nazareth, D., Downey, D., Rosenbluth, D., Isabelle Fajac, Malfroot, A., Bakker, M., Wirsching, G., Hoffmann, A., Rowe, S. M., Ratjen, F.

المساهمون: Growth and Development, Vriendenkring VUB

المصدر: Web of Science

مصطلحات موضوعية: RIO-CF study, cf patients, riociguat, adult Phe508del homozygous, Safety, tolerability, Phe508del homozygous

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::abb14e2e32181b2c543f464b0813b3ed
https://biblio.vub.ac.be/vubir/safety-tolerability-and-early-signs-of-efficacy-with-riociguat-for-the-treatment-of-adult-phe508del-homozygous-cystic-fibrosis-patients-safety-data-from-the-riocf-study(492da645-5d91-445b-a69c-0e181a8a71ab).html

المؤلفون: Taylor-Cousar, J. L.^1,2, Janssen, J. S.¹, Wilson, A.¹, Clair, C. G. St.¹, Pickard, K. M.¹, Jones, M. C.³, Brayshaw, S. J.¹, Chacon, C. S.¹, Barboa, C. M.¹, Sontag, M. K.⁴, Accurso, F. J.³, Nichols, D. P.^1,2, Saavedra, M. T.¹, Nick, J. A.¹

المصدر: Journal of Diabetes Research. 11/24/2016, p1-8. 8p.

مصطلحات موضوعية: *CYSTIC fibrosis diagnosis, *CYSTIC fibrosis, *PHYSIOLOGICAL effects of glucose, *COMORBIDITY, *GLUCOSE tolerance tests, *DISEASE risk factors, DISEASES in adults

المؤلفون: Davies, J. C.¹, Moskowitz, S. M.¹, Brown, C.¹, Horsley, A.¹, Mall, M. A.¹, McKone, E. F.¹, Plant, B. J.¹, Prais, D.¹, Ramsey, B. W.¹, Taylor-Cousar, J. L.¹, Tullis, E.¹, Uluer, A.¹, McKee, C. M.¹, Robertson, S.¹, Shilling, R. A.¹, Simard, C.¹, Van Goor, F.¹, Waltz, D.¹, Xuan, F.¹, Young, T.¹

المصدر: New England Journal of Medicine. 10/25/2018, Vol. 379 Issue 17, p1599-1611. 13p.

مصطلحات موضوعية: *CHLORIDES analysis, *ALLELES, *CELL culture, *COMBINATION drug therapy, *CLINICAL trials, *COMPARATIVE studies, *CYSTIC fibrosis, *HETEROCYCLIC compounds, *LAXATIVES, *RESEARCH methodology, *MEDICAL cooperation, *MEMBRANE proteins, *GENETIC mutation, *PERSPIRATION, *PHENOLS, *QUINOLONE antibacterial agents, *RESEARCH, *RESEARCH funding, *EVALUATION research, *RANDOMIZED controlled trials, *VITAL capacity (Respiration), *BLIND experiment, *GENOTYPES, *INDOLE compounds, *THERAPEUTICS