المؤلفون: Nowrouzi, Behnaz, Li, Rachel A, Walls, Laura E, d’Espaux, Leo, Malcı, Koray, Liang, Lungang, Jonguitud-Borrego, Nestor, Lerma-Escalera, Albert I, Morones-Ramirez, Jose R, Keasling, Jay D, Rios-Solis, Leonardo

المصدر: Microbial Cell Factories. 19(1)

مصطلحات موضوعية: Biological Sciences, Industrial Biotechnology, Responsible Consumption and Production, Alkenes, Antineoplastic Agents, Bioreactors, Diterpenes, Escherichia coli, Isomerases, Metabolic Engineering, Saccharomyces cerevisiae, Solubility, Temperature, Taxadiene synthase, Paclitaxel, Taxol™, Yeast metabolic engineering, Minibioreactor, Taxol™, Microbiology, Biotechnology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6f21923t

المؤلفون: Behnaz Nowrouzi, Rachel A. Li, Laura E. Walls, Leo d’Espaux, Koray Malcı, Lungang Liang, Nestor Jonguitud-Borrego, Albert I. Lerma-Escalera, Jose R. Morones-Ramirez, Jay D. Keasling, Leonardo Rios-Solis

المصدر: Microbial Cell Factories, Vol 19, Iss 1, Pp 1-12 (2020)

مصطلحات موضوعية: Taxadiene synthase, Saccharomyces cerevisiae, Paclitaxel, Taxol™, Yeast metabolic engineering, Minibioreactor, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12934-020-01458-2; https://doaj.org/toc/1475-2859

URL الوصول: https://doaj.org/article/a87fb7aff08248b2a3922231dfcb72be

المؤلفون: El-Sayed, Ashraf S. A., Fathalla, Maher, Shindia, Ahmed A., Rady, Amgad M., El-Baz, Ashraf F., Morsy, Yara, Sitohy, Basel, Sitohy, Mahmoud

المصدر: Scientia pharmaceutica. 89(4)

مصطلحات موضوعية: Factorial design optimization, Taxadiene, Taxadiene synthase, Taxol, Terpene cyclase

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190003
https://doi.org/10.3390/scipharm89040048
https://umu.diva-portal.org/smash/get/diva2:1617531/FULLTEXT01.pdf

المؤلفون: Palframan, MJ, Bandi, KK, Hamilton, JGC, Pattenden, G

المساهمون: School of Chemistry, The University of Nottingham, University Park, Nottingham NG7 2RD, UK.

المصدر: 59 ; 20 ; 1921 ; 1923

مصطلحات موضوعية: verticillenes, Sand fly, Taxadiene synthase, Insect pheromone, Lutzomyia longipalpis

وصف الملف: application/pdf

Relation: https://www.sciencedirect.com/science/article/pii/S0040403918304258?via%3Dihub; Palframan, M. J., Bandi, K. K., Hamilton, J. G. C. and Pattenden, G. (2018) Sobralene, a new sex-aggregation pheromone and likely shunt metabolite of the taxadiene synthase cascade, produced by a member of the sand fly Lutzomyia longipalpis species complex, Tetrahedron Letters, 59(2), pp. 1921-1923.; http://hdl.handle.net/2436/623042; Tetrahedron Letters

الاتاحة: http://hdl.handle.net/2436/623042
https://doi.org/10.1016/j.tetlet.2018.03.088

المؤلفون: Mijeong Cha1, Sang Hee Shim1, Sung Hong Kim2, Ok Tae Kim3, Se-Weon Lee4, Suk-Yoon Kwon5 & Kwang-Hyun Baek1,

المصدر: BMB Reports, Vol 45, Iss 10, Pp 589-594 (2012)

مصطلحات موضوعية: Panax ginseng C.A. Meyer, Root culture, Taxadiene synthase, Taxol, Transformation, Biology (General), QH301-705.5, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMCU1RDEyMTAyOTIxMjVfJTI4NTg5LTU5NCUyOUJNQl8xMi0wODUucGRm; https://doaj.org/toc/1976-6696; https://doaj.org/toc/1976-670X

URL الوصول: https://doaj.org/article/96fe1cbe4cea43409b74fd2f0dc6e011

المؤلفون: Mahmoud Sitohy, Yara Morsy, Ashraf S.A. El-Sayed, Ahmed A. Shindia, Maher Fathalla, Ashraf F. El-Baz, Amgad M. Rady, Basel Sitohy

المصدر: Scientia Pharmaceutica; Volume 89; Issue 4; Pages: 48
Scientia Pharmaceutica, Vol 89, Iss 48, p 48 (2021)

مصطلحات موضوعية: Terpene cyclase, Taxadiene synthase, Taxol, Taxadiene, Pharmaceutical Science, Microbiology, Plant use of endophytic fungi in defense, Cofactor, chemistry.chemical_compound, Pharmacy and materia medica, Factorial design optimization, taxadiene, chemistry.chemical_classification, ATP synthase, biology, taxadiene synthase, terpene cyclase, factorial design optimization, Active site, biology.organism_classification, RS1-441, Stenotrophomonas maltophilia, Mikrobiologi, Enzyme, chemistry, Biochemistry, biology.protein

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c47aa4dd775ea0f8d85a8df364c21b7
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190003

المؤلفون: Kaibo Wang, Lei Yang, Yong Wang, Ishmael Mutanda, Jianhua Li, Jiawei Wang

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Chloroplasts, Paclitaxel, viruses, Science, Genetic Vectors, General Physics and Astronomy, Nicotiana benthamiana, Molecular engineering in plants, Alkenes, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Metabolic engineering, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Biosynthesis, Tobacco, Isomerases, lcsh:Science, NADPH-Ferrihemoprotein Reductase, Nicotiana, Multidisciplinary, biology, Terpenes, fungi, Taxadiene, Cytochrome P450 reductase, food and beverages, General Chemistry, biology.organism_classification, Chloroplast, 030104 developmental biology, Metabolic Engineering, chemistry, Biochemistry, Taxadiene synthase, biology.protein, Taxoids, lcsh:Q, Diterpenes, Taxus, Secondary metabolism, 010606 plant biology & botany

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271389e2da66d2e99c0ee661793a67b0
https://doaj.org/article/8428c9211e514f2db08b62a0cc8920f5

المؤلفون: Andrés M. Escorcia, Walter Thiel, Jeaphianne van Rijn

المصدر: Journal of Computational Chemistry. 40:1902-1910

مصطلحات موضوعية: Reaction mechanism, Stereochemistry, Alkenes, Molecular Dynamics Simulation, Carbocation, 010402 general chemistry, 01 natural sciences, Enzyme catalysis, QM/MM, chemistry.chemical_compound, Deprotonation, 0103 physical sciences, Isomerases, Molecular Structure, 010304 chemical physics, biology, Chemistry, Taxadiene, General Chemistry, 0104 chemical sciences, Diphosphates, Computational Mathematics, Taxadiene synthase, Biocatalysis, biology.protein, Quantum Theory, Enzyme promiscuity, Diterpenes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae0f4ee3929f26120ed11d01af7644c
https://doi.org/10.1002/jcc.25846

المؤلفون: Ying Chen, Hua Zhang, Meng Zhang, Wenli Zhang, Ziqi Ou, Zehang Peng, Chunhua Fu, Chunfang Zhao, Longjiang Yu

المصدر: Frontiers in Plant Science, Vol 12 (2021)
Frontiers in Plant Science

مصطلحات موضوعية: chemistry.chemical_classification, Methyl jasmonate, biology, Activator (genetics), WRKY transcription factor, Plant culture, Plant Science, biology.organism_classification, taxol biosynthesis, SB1-1110, chemistry.chemical_compound, Enzyme, Biochemistry, Taxus, chemistry, RNA interference, Taxadiene synthase, biology.protein, TcERF15, Gene, SA signal, Salicylic acid, Taxus chinensis 3, Original Research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e811ce98ec5b215861a5f7aee9faf38c
https://www.frontiersin.org/articles/10.3389/fpls.2021.697476/full

المؤلفون: Chow, Siew Yin

Thesis Advisors: Scott, A. Ian

مصطلحات موضوعية: TAXADIENE SYNTHASE

وصف الملف: 4856876 bytes; electronic; application/pdf; born digital

الاتاحة: http://hdl.handle.net/1969.1/3966

المؤلفون: Bipeng Wang, Ling Chang, Wei Huang, Wenbo Xu, Shengchun Li, Jinqiu Fu, Jiang Zhang

المصدر: Planta. 253

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Chloroplasts, Geranylgeranyl pyrophosphate, Plant Science, Mevalonic acid, Genetically modified crops, Alkenes, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Tobacco, Genetics, Isomerases, biology, Taxadiene, food and beverages, Chloroplast, Transformation (genetics), 030104 developmental biology, chemistry, Biochemistry, Taxadiene synthase, biology.protein, Diterpenes, 010606 plant biology & botany, Transplastomic plant

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b764a829462648d71446235b43f446c7
https://doi.org/10.1007/s00425-021-03626-z

المؤلفون: Soliman, Sameh SM, Trobacher, Christopher P, Tsao, Rong, Greenwood, John S, Raizada, Manish N

مصطلحات موضوعية: Taxus, Paraconiothyrium, Fungus, Endophyte, Taxol, Biosynthesis, Fungicide, DXR, Taxadiene synthase

Relation: http://www.biomedcentral.com/1471-2229/13/93

الاتاحة: http://www.biomedcentral.com/1471-2229/13/93

المؤلفون: Gerald Pattenden, Matthew J. Palframan

المصدر: Natural Product Reports. 36:108-121

مصطلحات موضوعية: Quantum chemical, Taxane, biology, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, chemistry.chemical_compound, Biosynthesis, Biomimetics, Taxadiene synthase, Biomimetic synthesis, Drug Discovery, biology.protein, Epoxy Compounds, Taxoids, Diterpenes, Heterocyclic Compounds, 3-Ring

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b7d754a4ba6e137e5e5ae13539275f
https://doi.org/10.1039/c8np00034d

المؤلفون: Marta Grech-Baran, Katarzyna Sykłowska-Baranek, Jacek Hennig, Wojciech Rymaszewski, Agnieszka Pietrosiuk, P. Rokicki, Maciej Pilarek, M. Gaweł

المصدر: Plant Cell Reports

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Perfluorodecalin, Plant Science, Plant Roots, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, Gene Expression Regulation, Plant, Isomerases, Fluorocarbons, Taxane, Methyl jasmonate, biology, Hairy roots, Taxus × media, Elicitation, General Medicine, biology.organism_classification, Molecular biology, Elicitor, 030104 developmental biology, chemistry, Paclitaxel, Taxus, Taxadiene synthase, Baccatin III, biology.protein, Original Article, Gene expression, Agronomy and Crop Science, 010606 plant biology & botany

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514060941e7aaeef28152add19f7310c
https://doi.org/10.1007/s00299-018-2351-0

المؤلفون: Yehoshua Freud, Tamar Ansbacher, Dan Thomas Major

المصدر: Biochemistry. 57:3773-3779

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Mutant, Alkenes, 010402 general chemistry, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Protein structure, Biosynthesis, Catalytic Domain, Point Mutation, Isomerases, Salvia officinalis, Plant Proteins, chemistry.chemical_classification, Natural product, biology, 010405 organic chemistry, Taxadiene, Active site, Biosynthetic Pathways, 0104 chemical sciences, Enzyme, chemistry, Taxadiene synthase, biology.protein, Thermodynamics, Diterpenes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408bbb7115eba146ac3ff5840bca4ce3
https://doi.org/10.1021/acs.biochem.8b00452

المؤلفون: Thomas Brück, Patrick Schrepfer, Andrés M. Escorcia, Walter Thiel, Jeaphianne van Rijn, Gui-Juan Cheng

المصدر: Journal of Computational Chemistry. 39:1215-1225

مصطلحات موضوعية: biology, 010405 organic chemistry, Chemistry, Stereochemistry, Taxadiene, General Chemistry, Carbocation, 010402 general chemistry, 01 natural sciences, Pyrophosphate, 0104 chemical sciences, Catalysis, Computational Mathematics, Molecular dynamics, chemistry.chemical_compound, Deprotonation, Taxadiene synthase, biology.protein, Enzyme promiscuity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8e32eff1d7bfd59c874e044e55239a
https://doi.org/10.1002/jcc.25184

المؤلفون: Dan Thomas Major, Yehoshua Freud, Tamar Ansbacher

المصدر: ACS Catalysis. 7:7653-7657

مصطلحات موضوعية: chemistry.chemical_classification, Proton, biology, 010405 organic chemistry, Stereochemistry, General Chemistry, 010402 general chemistry, Lyase, 01 natural sciences, Catalysis, 0104 chemical sciences, Enzyme catalysis, chemistry.chemical_compound, Enzyme, chemistry, Biosynthesis, Taxadiene synthase, Intramolecular force, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d4dc84af76d11d7d39d72260ddf10b06
https://doi.org/10.1021/acscatal.7b02824

المؤلفون: Aldwin M. Anterola, Laxmi Sagwan-Barkdoll

المصدر: Biotechnology and Applied Biochemistry. 65:294-305

مصطلحات موضوعية: 0301 basic medicine, genetic structures, Biomedical Engineering, Bioengineering, Alkenes, medicine.disease_cause, Applied Microbiology and Biotechnology, Article, 03 medical and health sciences, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Drug Discovery, Cytochrome b5, Escherichia coli, medicine, chemistry.chemical_classification, Taxane, biology, Process Chemistry and Technology, Taxadiene, Cytochrome P450 reductase, General Medicine, biology.organism_classification, eye diseases, 030104 developmental biology, Enzyme, chemistry, Biochemistry, Taxadiene synthase, biology.protein, Molecular Medicine, sense organs, Diterpenes, Taxus, Taxus cuspidata, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e786fbc8f03b8acd01263feeaf00e2e0
https://doi.org/10.1002/bab.1606

المؤلفون: Golda G. Harris, Lian Duan, Travis A. Pemberton, Alex S. Genshaft, Mustafa Köksal, David W. Christianson, Wayne K. W. Chou, David E. Cane, Mengbin Chen

المصدر: Biochemistry. 56:2010-2023

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Sesterterpenes, Architecture domain, Stereochemistry, Mutant Chimeric Proteins, Gene Expression, Protein Engineering, Biochemistry, Article, Protein Structure, Secondary, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Isomerases, chemistry.chemical_classification, Alkyl and Aryl Transferases, ATP synthase, biology, biology.organism_classification, Terpenoid, Kinetics, Aspergillus, 030104 developmental biology, Enzyme, chemistry, Cyclization, Taxadiene synthase, Saccharomycetales, Domain (ring theory), biology.protein, Diterpenes, Taxus, Diterpene, Aspergillus clavatus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b038351457cc5a10bf66f3eaf494c84
https://doi.org/10.1021/acs.biochem.7b00137

المؤلفون: Gerald Pattenden, Matthew J. Palframan, Krishna K. Bandi, James G. C. Hamilton

مصطلحات موضوعية: biology, 010405 organic chemistry, Chemistry, Stereochemistry, Metabolite, Organic Chemistry, Taxadiene, Lutzomyia longipalpis, 010402 general chemistry, biology.organism_classification, 01 natural sciences, 0104 chemical sciences, Sandfly, chemistry.chemical_compound, Taxadiene synthase, biology.protein, Pheromone

وصف الملف: text

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2192e82eb6a264c5cfe66cf38bf112b4
https://doi.org/10.1055/s-0039-1690131