المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/dataset/Table_of_parameter_values_used_in_the_simulations_shown_in_Fig_6_unlisted_parameters_have_identical_values_as_in_S1_Table_/15062198

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s002

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Steady-state_analysis_as_a_function_of_diffusive_tau_fraction_i_f_i_/15062207

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s005

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Convergence_of_individual_simulations_to_steady_state_/15062201

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s003

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/dataset/Table_of_all_parameter_values_used_in_the_simulations_shown_in_Figs_2_3_and_5_see_Methods_for_a_full_description_of_each_parameter_/15062195

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s001

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Steady-state_analysis_as_a_function_of_fragmentation_rate_i_i_/15062204

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s004

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Somatodendritic_seeding_net-unbiased_bias_parameter_values_/15062216

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s008

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Somatodendritic_seeding_anterograde-biased_parameter_values_/15062210

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s006

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Somatodendritic_seeding_retrograde-biased_parameter_values_/15062213

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s007

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Transport_model_bias_versus_mouse_network_bias_scatterplot_/15062219

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s009

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/media/Video_of_the_complete_simulation_summarized_in_Fig_2a_/15062222

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s010

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/media/Video_of_the_complete_simulation_summarized_in_Fig_2b_/15062225

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s011

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Model_System_/15062231

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.g001

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/media/Video_of_the_complete_simulation_summarized_in_Fig_2c_/15062228

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.s012

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Steady-state_bias_analysis_as_a_function_of_aggregation_rate_/15062240

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.g004

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Temporal_profiles_of_somatodendritic_tau_deposition_/15062237

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.g003

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Model_regimes_are_determined_by_tau_transport_feedback_parameters_i_i_and_i_i_/15062234

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.g002

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Perturbation_of_initial_conditions_does_not_affect_steady_state_/15062243

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.g005

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/figure/Tau_transport_feedback_recaptures_the_directionality_of_mouse_tauopathy_models_/15062246

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.g006

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/dataset/Glossary_of_symbols_used_throughout_the_text_/15062249

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.t001

المؤلفون: Justin Torok (11191838), Pedro D. Maia (3617321), Parul Verma (1974475), Christopher Mezias (11191841), Ashish Raj (156100)

مصطلحات موضوعية: Biophysics, Medicine, Genetics, Neuroscience, Biotechnology, Mental Health, Biological Sciences not elsewhere classified, tau-modified axonal transport, spatiotemporal profiles, non-AD-like mouse tauopathy models, axonal transport dynamics Defects, tau species, axonal transport, two-neuron system, Tau transport feedback, network spread biases, fragmentation parameters, disease-specific fashion, tau deposition, time scales, tau pathology, non-amyloidogenic tauopathies, anterograde-directed transport, dysregulate motor proteins, tau variants, tau transport feedback parameters

Relation: https://figshare.com/articles/dataset/Table_indicating_which_processes_are_modeled_in_each_biological_compartment_/15062252

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009258.t002