المؤلفون: Tashinga E. Bapiro, Rose Hayeshi, Collet Dandara

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: pharmacokinetics, anticancer drugs, pharmacodynamics, drug metabolism, drug-drug interactions, cytochrome P450, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.972718/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/94f0677d1df44537bd7a3a2ec93c188e

المؤلفون: David A. Tuveson, Duncan I. Jodrell, Martijn P. Lolkema, Tashinga E. Bapiro, Natalie Cook, Albrecht Neesse, Kristopher K. Frese

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3702740853cd3b96cb65c6aebb68ad06
https://doi.org/10.1158/2159-8290.c.6546821.v1

المؤلفون: David A. Tuveson, Duncan I. Jodrell, Martijn P. Lolkema, Tashinga E. Bapiro, Natalie Cook, Albrecht Neesse, Kristopher K. Frese

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae98bbed8704fdac2d98a1fac405401
https://doi.org/10.1158/2159-8290.22532762.v1

المؤلفون: David A. Tuveson, Duncan I. Jodrell, Martijn P. Lolkema, Tashinga E. Bapiro, Natalie Cook, Albrecht Neesse, Kristopher K. Frese

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e49a8186c7033946a2ae21f29ea1a8c
https://doi.org/10.1158/2159-8290.22532768

المؤلفون: David A. Tuveson, Duncan I. Jodrell, Martijn P. Lolkema, Tashinga E. Bapiro, Natalie Cook, Albrecht Neesse, Kristopher K. Frese

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981ca6cdb2f433ca6c59d1e551f31410
https://doi.org/10.1158/2159-8290.22532765.v1

المؤلفون: David A. Tuveson, Youngkyu Park, Duncan I. Jodrell, Kenneth H. Yu, Paul Smith, Pearl Huang, Tashinga E. Bapiro, Kevin Wright, Dea Filippini, Lindsey A. Baker, Iok In Christine Chio, Daniel Öhlund, Chang-Il Hwang, Tobiloba E. Oni, Kristopher K. Frese, Dannielle D. Engle, Hervé Tiriac, Vincenzo Corbo, Mariano Ponz-Sarvise

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3e93ddb67be2d51b95b7b517279251
https://doi.org/10.1158/1078-0432.c.6528179.v1

المؤلفون: David A. Tuveson, Youngkyu Park, Duncan I. Jodrell, Kenneth H. Yu, Paul Smith, Pearl Huang, Tashinga E. Bapiro, Kevin Wright, Dea Filippini, Lindsey A. Baker, Iok In Christine Chio, Daniel Öhlund, Chang-Il Hwang, Tobiloba E. Oni, Kristopher K. Frese, Dannielle D. Engle, Hervé Tiriac, Vincenzo Corbo, Mariano Ponz-Sarvise

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4d51b5fe19cd2bac155356020f3487
https://doi.org/10.1158/1078-0432.22472273

المؤلفون: Tashinga E. Bapiro, Scott Martin, Stephen D Wilkinson, Alexandra L. Orton, Niresh Hariparsad, Stephanie Harlfinger, Dermot F McGinnity

المصدر: Drug Metabolism and Disposition. :DMD-AR

مصطلحات موضوعية: Pharmacology, Pharmaceutical Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::012c7e50c11486943a74a394d0b4eb43
https://doi.org/10.1124/dmd.123.001323

المؤلفون: Aurélie Courtin, Frances M Richards, Tashinga E Bapiro, Jo L Bramhall, Albrecht Neesse, Natalie Cook, Ben-Fillippo Krippendorff, David A Tuveson, Duncan I Jodrell

المصدر: PLoS ONE, Vol 8, Iss 6, p e67330 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3696095?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/e84923692d2b48e9bbd3ce4de3f87151

المؤلفون: Michael Davies, Scott W. Martin, Tashinga E. Bapiro, Helen Rollison, James W.T. Yates, Andy Sykes, Matthias Hoch, Barry Jones

المصدر: Drug Metabolism and Disposition. 46:1268-1276

مصطلحات موضوعية: Male, 0301 basic medicine, Indoles, Cytochrome, Administration, Oral, Pharmaceutical Science, Estrogen receptor, Substrate Specificity, Cytochrome P-450 CYP2C8, 03 medical and health sciences, Humans, Binding site, Receptor, Pharmacology, Dose-Response Relationship, Drug, biology, Chemistry, Substrate (chemistry), Cytochrome P-450 CYP2C8 Inhibitors, 030104 developmental biology, Receptors, Estrogen, Biochemistry, Cinnamates, Microsomes, Liver, Microsome, biology.protein, Female, Uncompetitive inhibitor, Cytochrome P450 2C8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64630c2477542c1fe35d686fa058554b
https://doi.org/10.1124/dmd.118.081539

المؤلفون: Nicholas Ekow Thomford, Tashinga E. Bapiro, Collet Dandara

المصدر: Clinical Pharmacology & Therapeutics. 106:302-304

مصطلحات موضوعية: Pharmacology, Drug, Plants, Medicinal, Drug-Related Side Effects and Adverse Reactions, business.industry, media_common.quotation_subject, Herb-Drug Interactions, MEDLINE, Bioinformatics, Phenotype, Culprit, Pharmacotherapy, Drug Therapy, Pharmacogenetics, Pharmacogenomics, Humans, Medicine, Pharmacology (medical), Precision Medicine, business, Biotransformation, Throwing, Phytotherapy, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e824dadf6b6f4581ca3c0edfee451f87
https://doi.org/10.1002/cpt.1509

المؤلفون: Yao Lin, A. Robertson, Duncan I. Jodrell, Jo L. Bramhall, Jennifer Harrington, Daniella Zheleva, Tashinga E. Bapiro, Frances M. Richards, B-F Krippendorff

المساهمون: Richards, Fran [0000-0001-7947-7853], Jodrell, Duncan [0000-0001-9360-1670], Apollo - University of Cambridge Repository

المصدر: British Journal of Cancer

مصطلحات موضوعية: Cancer Research, Paclitaxel, pancreatic cancer, Bone Marrow Cells, Pharmacology, Protein Serine-Threonine Kinases, Granulocyte-Macrophage Progenitor Cells, chemistry.chemical_compound, Aurora Kinases, Precursor cell, Pancreatic cancer, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, Protein Kinase Inhibitors, Aurora Kinase A, Protein-Serine-Threonine Kinases, business.industry, Stem Cells, Drug Synergism, medicine.disease, Pancreatic Neoplasms, medicine.anatomical_structure, Oncology, chemistry, embryonic structures, Cancer research, combination treatment, Bone marrow, biological phenomena, cell phenomena, and immunity, Stem cell, business, Translational Therapeutics, CYC3, mitotic inhibitor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2a40840c1c7c497781bc2aeb45ad98

المؤلفون: Roshini Markandu, Barry Jones, Tashinga E. Bapiro, Venkatesh Pilla Reddy, Adrian J. Fretland, Alexandra L. Orton

مصطلحات موضوعية: chemistry.chemical_classification, Drug, Physiologically based pharmacokinetic modelling, business.industry, media_common.quotation_subject, Monooxygenase, Pharmacology, Enzyme, chemistry, Pharmacokinetics, Medicine, Risk assessment, business, Aldehyde oxidase, Drug metabolism, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3e50eb495e69b070c2f0c2f59936716e
https://doi.org/10.1016/b978-0-12-820018-6.00007-7

المؤلفون: Farah Al Qaraghuli, Ravindra Varma Alluri, Sophie M.A. Argon, Piyush Bajaj, Tashinga E. Bapiro, Abdul Basit, Andreas Brink, Tingting Cai, Jose Castro-Perez, Jae H. Chang, Eugene Chia-Te Chen, Marie Croft, Liam Evans, Raymond Evers, Robert S. Foti, Adrian J. Fretland, Christopher Gemski, Anima Ghosal, Jia Hao, Satyajeet Haridas, Simon Hauri, Nina Isoherranen, Wenying Jian, Kevin Johnson, Barry Jones, Robert S. Jones, Jan Felix Joseph, S. Cyrus Khojasteh, Yurong Lai, Hoa Le, Xiaomin Liang, Liming Liu, Filipe Lopes, Justin Q. Ly, Shuguang Ma, Roshini Markandu, Rosalinde Masereeuw, J. Eric McDuffie, Kaushik Mitra, Diana Montgomery, Alexandra L. Orton, Katie H. Owens, Axel Pähler, Maria Kristina Parr, Shefali Patel, Ichiko D. Petrie, Richard Phipps, Chandra Prakash, Bhagwat Prasad, Isabelle Ragueneau-Majlessi, Venkatesh Pilla Reddy, Ellen Riddle, Qian Ruan, Simone Schadt, Dhaval K. Shah, Julia Shanu-Wilson, Kelly MacLennan Staiger, Jonathan Steele, Manthena V.S. Varma, Matthew P. Wagoner, Naidong Weng, Stephen Wrigley, Caisheng Wu, Graeme C. Young, Jingjing Yu, Lushan Yu, Su Zeng, Haeyoung Zhang, Wanying Zhang, Andy Z.X. Zhu, Mingshe Zhu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::32563bc881f8145ec2036a1b650e62de
https://doi.org/10.1016/b978-0-12-820018-6.09990-7

المؤلفون: Hervé Tiriac, Young-Kyu Park, Kristopher K. Frese, Vincenzo Corbo, Kevin Wright, David A. Tuveson, Kenneth H. Yu, Tobiloba E. Oni, Paul D. Smith, Tashinga E. Bapiro, Mariano Ponz-Sarvise, Daniel Öhlund, Dannielle D. Engle, Dea Filippini, Lindsey A. Baker, Duncan I. Jodrell, Iok In Christine Chio, Pearl S. Huang, Chang-Il Hwang

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 25, iss 22
Clin Cancer Res

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cancer Research, endocrine system diseases, Drug Resistance, medicine.disease_cause, Transgenic, Tissue Culture Techniques, Mice, 0302 clinical medicine, Phosphorylation, Cancer, Tumor, Effector, MOUSE MODEL, CHEMOTHERAPY, Organoids, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, GROWTH, KRAS, Drug, Development of treatments and therapeutic interventions, ARRY-142886, Signal Transduction, Oncology and Carcinogenesis, Mice, Transgenic, Antineoplastic Agents, Biology, Malignancy, Article, Cell Line, Dose-Response Relationship, 03 medical and health sciences, Pancreatic Cancer, Rare Diseases, ErbB, Clinical Research, Pancreatic cancer, Cell Line, Tumor, RAS ONCOGENES, medicine, Organoid, Animals, Humans, Oncology & Carcinogenesis, MEK INHIBITION, COMBINATION, neoplasms, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Dose-Response Relationship, Drug, Animal, PI3K INHIBITION, GEMCITABINE, medicine.disease, digestive system diseases, respiratory tract diseases, Pancreatic Neoplasms, Disease Models, Animal, 030104 developmental biology, Drug Resistance, Neoplasm, Disease Models, Cancer research, Neoplasm, Digestive Diseases, Proto-Oncogene Proteins c-akt

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923cc4865d0e2635cc430ae41a1abc4d
https://escholarship.org/uc/item/6k28v7vh

المؤلفون: Yann Wallez, Duncan I. Jodrell, Charles R. Dunlop, Siang-Boon Koh, Frances M. Richards, Tashinga E. Bapiro, Sandra Bernaldo de Quirós Fernández

المصدر: Cancer research. 78(11)

مصطلحات موضوعية: 0301 basic medicine, DNA Replication, Cancer Research, DNA damage, medicine.medical_treatment, Mice, Nude, Cell Cycle Proteins, Deoxycytidine, Article, 03 medical and health sciences, Mice, Cyclin-dependent kinase, Chemosensitization, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Animals, Humans, CHEK1, Cell Proliferation, Chemotherapy, Mice, Inbred BALB C, biology, business.industry, Nuclear Proteins, Drug Synergism, Protein-Tyrosine Kinases, Xenograft Model Antitumor Assays, Gemcitabine, Wee1, 030104 developmental biology, Oncology, Tolerability, Checkpoint Kinase 1, biology.protein, Cancer research, Female, business, medicine.drug, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b00f9a1c95d935ba424dbe5d155c9b1
https://pubmed.ncbi.nlm.nih.gov/29735549

المؤلفون: Tashinga E. Bapiro, Duncan I. Jodrell, John R. Griffiths, D. Smith, David A. Tuveson, Kenneth P. Olive, Mae A. Goldgraben, Kristopher K. Frese, Basetti Madhu, Michael A. Jacobetz, Frances M. Richards, Natalie Cook

المساهمون: Richards, Fran [0000-0001-7947-7853], Goldgraben, Mae [0000-0002-1111-2804], Griffiths, John [0000-0001-7369-6836], Jodrell, Duncan [0000-0001-9360-1670], Apollo - University of Cambridge Repository

المصدر: Cancer Chemotherapy and Pharmacology

مصطلحات موضوعية: Cancer Research, Cytidine triphosphate, Magnetic Resonance Spectroscopy, Cytidine Triphosphate, Antineoplastic Agents, Tandem mass spectrometry, Toxicology, Deoxycytidine, Tumour tissue, chemistry.chemical_compound, Mice, NMR spectroscopy, Floxuridine, Tandem Mass Spectrometry, Pancreatic cancer, medicine, Animals, Humans, Pharmacology (medical), Pharmacology, Chromatography, Mass spectrometry, Chemistry, Nuclear magnetic resonance spectroscopy, Fluorine, Reference Standards, medicine.disease, Gemcitabine, Disease Models, Animal, Biochemistry, Oncology, Calibration, Original Article, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34207630f55e3469b7de3f02ac9728d

المؤلفون: Volker Ellenrieder, Kristopher K. Frese, Duncan I. Jodrell, David A. Tuveson, Frances M. Richards, William J. Howat, Derek S. Chan, Tashinga E. Bapiro, Albrecht Neesse

المصدر: Gut
Gut; Vol 63

مصطلحات موضوعية: Paclitaxel, Adenocarcinoma, Pharmacology, medicine.disease_cause, Polyethylene Glycols, Animals, Genetically Modified, Mice, Pancreatic Cancer, chemistry.chemical_compound, Pharmacokinetics, Albumins, Pancreatic cancer, medicine, Animals, Osteonectin, Dose-Response Relationship, Drug, biology, business.industry, Gastroenterology, medicine.disease, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, 3. Good health, Pancreatic Neoplasms, chemistry, Drug delivery, Toxicity, biology.protein, Collagen, KRAS, Albumin-Bound Paclitaxel, Pharmaceutical Vehicles, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8503ebc2bf9a5701937cea2e537254f0
https://doi.org/10.1136/gutjnl-2013-305559

المؤلفون: Kristopher K. Frese, Duncan I. Jodrell, Albrecht Neesse, Tashinga E. Bapiro, Melanie S. Patzak, Elisabeth Hessmann, Volker Ellenrieder

المصدر: Zeitschrift für Gastroenterologie. 54

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Gastroenterology, Metabolism, medicine.disease, Gemcitabine, Pancreatic cancer, Internal medicine, medicine, Cancer-Associated Fibroblasts, CA19-9, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b5c8324e19ad398fbbd6688770823cf3
https://doi.org/10.1055/s-0036-1587242

المؤلفون: Tashinga E, Bapiro, Frances M, Richards, Duncan I, Jodrell

المصدر: Analytical Chemistry

مصطلحات موضوعية: Technical Note

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::dc3c4256be9205384807fe96141482f2
https://pubmed.ncbi.nlm.nih.gov/27228284