المؤلفون: Arezo Torang, Aleksandar B. Kirov, Veerle Lammers, Kate Cameron, Valérie M. Wouters, Rene F. Jackstadt, Tamsin R. M. Lannagan, Joan H. de Jong, Jan Koster, Owen Sansom, Jan Paul Medema

المصدر: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d30874535a2f4405a197ebf7d3ce5dd4

المؤلفون: Reshmi Nair, Tamsin R. M. Lannagan, Rene Jackstadt, Anna Andrusaite, John Cole, Caitlin Boyne, Robert J. B. Nibbs, Owen J. Sansom, Simon Milling

المصدر: OncoImmunology, Vol 13, Iss 1 (2024)

مصطلحات موضوعية: immunotherapy, colorectal cancer, T-lymphocytes, myeloid cells, Check point inhibition, metabolism, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2162-402X

URL الوصول: https://doaj.org/article/990e4b206f444c4f9e950f6acf44d5d0

المؤلفون: Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards

المصدر: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)

مصطلحات موضوعية: Colorectal cancer, Cellular signaling, JAK/STAT3 signal transduction, Tumor microenvironment, Prognosis, Spatial biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-9966

URL الوصول: https://doaj.org/article/3b63169b435447a19a5fb490ee037279

المؤلفون: Candice R. Gurbatri, Georgette A. Radford, Laura Vrbanac, Jongwon Im, Elaine M. Thomas, Courtney Coker, Samuel R. Taylor, YoungUk Jang, Ayelet Sivan, Kyu Rhee, Anas A. Saleh, Tiffany Chien, Fereshteh Zandkarimi, Ioana Lia, Tamsin R. M. Lannagan, Tongtong Wang, Josephine A. Wright, Hiroki Kobayashi, Jia Q. Ng, Matt Lawrence, Tarik Sammour, Michelle Thomas, Mark Lewis, Lito Papanicolas, Joanne Perry, Tracy Fitzsimmons, Patricia Kaazan, Amanda Lim, Alexandra M. Stavropoulos, Dion A. Gouskos, Julie Marker, Cheri Ostroff, Geraint Rogers, Nicholas Arpaia, Daniel L. Worthley, Susan L. Woods, Tal Danino

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/16a3783ebc994816bc3440bb05df9c6f

المؤلفون: Jia Q. Ng, Toghrul H. Jafarov, Christopher B. Little, Tongtong Wang, Abdullah M. Ali, Yan Ma, Georgette A. Radford, Laura Vrbanac, Mari Ichinose, Samuel Whittle, David J. Hunter, Tamsin R. M. Lannagan, Nobumi Suzuki, Jarrad M. Goyne, Hiroki Kobayashi, Timothy C. Wang, David R. Haynes, Danijela Menicanin, Stan Gronthos, Daniel L. Worthley, Susan L. Woods, Siddhartha Mukherjee

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8fef35728baa46f097358d129ef88852

المؤلفون: Kathryn A. F. Pennel, Phimmada Hatthakarnkul, Colin S. Wood, Guang-Yu Lian, Sara S. F. Al-Badran, Jean A. Quinn, Assya Legrini, Jitwadee Inthagard, Peter G. Alexander, Hester van Wyk, Ahmad Kurniawan, Umar Hashmi, Michael A. Gillespie, Megan Mills, Aula Ammar, Jennifer Hay, Ditte Andersen, Colin Nixon, Selma Rebus, David K. Chang, Caroline Kelly, Andrea Harkin, Janet Graham, David Church, Ian Tomlinson, Mark Saunders, Tim Iveson, Tamsin R. M. Lannagan, Rene Jackstadt, Noori Maka, Paul G. Horgan, Campbell S. D. Roxburgh, Owen J. Sansom, Donald C. McMillan, Colin W. Steele, Nigel B. Jamieson, James H. Park, Antonia K. Roseweir, Joanne Edwards

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Colorectal cancer, Cellular signaling, JAK/STAT3 signal transduction, Tumor microenvironment, Prognosis, Spatial biology, JAK inhibitors, Tumor-stroma, Patient-derived organoids, Stratified medicine, Biomarkers

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_JAK_STAT3_represents_a_therapeutic_target_for_colorectal_cancer_patients_with_stromal-rich_tumors/25322908

الاتاحة: https://doi.org/10.6084/m9.figshare.25322908.v1
https://figshare.com/articles/journal_contribution/Additional_file_1_of_JAK_STAT3_represents_a_therapeutic_target_for_colorectal_cancer_patients_with_stromal-rich_tumors/25322908

المؤلفون: Eva C. Freckmann, Emma Sandilands, Erin Cumming, Matthew Neilson, Alvaro Román-Fernández, Konstantina Nikolatou, Marisa Nacke, Tamsin R. M. Lannagan, Ann Hedley, David Strachan, Mark Salji, Jennifer P. Morton, Lynn McGarry, Hing Y. Leung, Owen J. Sansom, Crispin J. Miller, David M. Bryant

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d1ea5c3909d0472cb9c9c41a696d4ec5

المؤلفون: Mari Ichinose, Nobumi Suzuki, Tongtong Wang, Josephine A. Wright, Tamsin R. M. Lannagan, Laura Vrbanac, Hiroki Kobayashi, Krystyna Gieniec, Jia Q. Ng, Souzaburo Ihara, Chris Mavrangelos, Yoku Hayakawa, Patrick Hughes, Daniel L. Worthley, Susan L. Woods

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/aebf352fe0324c3cb4059278bf6e460e

المؤلفون: Baharak Ahmaderaghi, Raheleh Amirkhah, James Jackson, Tamsin R. M. Lannagan, Kathryn Gilroy, Sudhir B. Malla, Keara L. Redmond, Gerard Quinn, Simon S. McDade, ACRCelerate Consortium, Tim Maughan, Simon Leedham, Andrew S. D. Campbell, Owen J. Sansom, Mark Lawler, Philip D. Dunne

المصدر: Disease Models & Mechanisms, Vol 15, Iss 3 (2022)

مصطلحات موضوعية: bioinformatics, data analytics, rna-seq, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/15/3/dmm049257; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/af0348220b314b64a6a61c4ef7c86992

المؤلفون: Catherine E. Bond, Cheng Liu, Futoshi Kawamata, Diane M. McKeone, Winnie Fernando, Saara Jamieson, Sally-Ann Pearson, Alexandra Kane, Susan L. Woods, Tamsin R. M. Lannagan, Roshini Somashekar, Young Lee, Troy Dumenil, Gunter Hartel, Kevin J. Spring, Jennifer Borowsky, Lochlan Fennell, Mark Bettington, Jason Lee, Daniel L. Worthley, Barbara A. Leggett, Vicki L. J. Whitehall

المصدر: Epigenetics, Vol 13, Iss 1, Pp 40-48 (2018)

مصطلحات موضوعية: braf, cancer biology, colorectal cancer, dna methylation, methylation, murine model, serrated neoplasia, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

URL الوصول: https://doaj.org/article/a0eb35f1f5c1498b9b8dd60644c1c526

المؤلفون: Raheleh Amirkhah, Kathryn Gilroy, Sudhir B. Malla, Tamsin R. M. Lannagan, Ryan M. Byrne, Natalie C. Fisher, Shania M. Corry, Noha-Ehssan Mohamed, Hojjat Naderi-Meshkin, Megan L. Mills, Andrew D. Campbell, Rachel A. Ridgway, Baharak Ahmaderaghi, Richard Murray, Antoni Berenguer Llergo, Rebeca Sanz-Pamplona, Alberto Villanueva, Eduard Batlle, Ramon Salazar, Mark Lawler, Owen J. Sansom, Philip D. Dunne

المصدر: Amirkhah, R, Gilroy, K, Malla, S B, Lannagan, T R M, Byrne, R M, Fisher, N C, Corry, S M, Mohamed, N-E, Naderi-Meshkin, H, Mills, M L, Campbell, A D, Ridgway, R A, Ahmaderaghi, B, Murray, R, Llergo, A B, Sanz-Pamplona, R, Villanueva, A, Batlle, E, Salazar, R, Lawler, M, Sansom, O J & Dunne, P D 2023, ' MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer ', British Journal of Cancer . https://doi.org/10.1038/s41416-023-02157-6

مصطلحات موضوعية: Cancer Research, Oncology, SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e444e4702c260519413f7be39de2c52d
https://pure.qub.ac.uk/en/publications/2e51b023-e9a5-4ddb-9012-f669f91865f3

المؤلفون: Susan L. Woods, Krystyna A. Gieniec, Eva M. Monsalve, Mari Ichinose, Tamsin R M Lannagan, Hiroki Kobayashi, Yoku Hayakawa, Josephine A. Wright, Jorge Laborda, Laura Vrbanac, Jia Q Ng, Tongtong Wang, Nobumi Suzuki, Patricia García-Gallastegui, Steven R. Bauer, Gaskon Ibarretxe, José J. García-Ramírez, Daniel L. Worthley

المصدر: American Journal of Physiology-Gastrointestinal and Liver Physiology. 320:G506-G520

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Mice, 129 Strain, Stromal cell, Physiology, Mesenchyme, Cell Communication, Biology, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), medicine, Animals, Cell Lineage, Intestinal Mucosa, Stem Cell Niche, Cells, Cultured, Embryonic Stem Cells, Cell Proliferation, Mice, Knockout, Secretory Pathway, Molecular signaling, Hepatology, Calcium-Binding Proteins, Gastroenterology, Gene Expression Regulation, Developmental, Cell Differentiation, Epithelial Cells, Intestinal epithelium, Coculture Techniques, Cell biology, Mice, Inbred C57BL, Organoids, 030104 developmental biology, DLK1, medicine.anatomical_structure, Stromal Cells, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d291651f38121a9933d88eae80fcab
https://doi.org/10.1152/ajpgi.00445.2020

المؤلفون: Ester Gil Vazquez, Nadia Nasreddin, Gabriel N Valbuena, Eoghan J Mulholland, Hayley L Belnoue-Davis, Holly Eggington, Ryan O Schenck, Valérie M Wouters, Pratyaksha Wirapati, Kathryn Gilroy, Tamsin R M Lannagan, Dustin J Flanagan, Arafath K Najumudeen, Sulochana Omwenga, Amy M B McCorry, Alistair Easton, Viktor H Koelzer, James E East, Dion Morton, Livio Trusolino, Timothy Maughan, Andrew D Campbell, Maurice B Loughrey, Philip D Dunne, Petros Tsantoulis, David J Huels, Sabine Tejpar, Owen Sansom, Simon J Leedham

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bbefa25d12c76480d625ba52678c0be8
https://doi.org/10.1101/2022.06.11.495729

المؤلفون: Owen J. Sansom, Tamsin R M Lannagan, Rene Jackstadt, Simon J. Leedham

المصدر: Current Opinion in Genetics & Development

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Treatment response, Colorectal cancer, Disease, Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, medicine, Tumor Microenvironment, Animals, Humans, 030304 developmental biology, 0303 health sciences, Stem Cells, Disease progression, medicine.disease, In vitro, Clinical trial, Human colon cancer, Organoids, Disease Models, Animal, Colonic Neoplasms, Stem cell biology, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323d781abe2f790014932dfe4189f251
http://europepmc.org/articles/PMC7985292

المؤلفون: Alastair D. Burt, Nobumi Suzuki, Mari Ichinose, Laura Vrbanac, Susan L. Woods, Krystyna A. Gieniec, Georgette Radford, Tamsin R M Lannagan, Jarrad M. Goyne, Masahide Takahashi, Tongtong Wang, Elaine M. Thomas, Hiroki Kobayashi, Atsushi Enomoto, Daniel L. Worthley, Josephine A. Wright, Jia Q Ng

المصدر: Journal of Visualized Experiments.

مصطلحات موضوعية: Stromal cell, Colorectal cancer, General Chemical Engineering, Mesenchyme, General Biochemistry, Genetics and Molecular Biology, Metastasis, Mice, Stroma, Tumor Microenvironment, Organoid, Animals, Humans, Medicine, Tumor microenvironment, General Immunology and Microbiology, Portal Vein, business.industry, General Neuroscience, Liver Neoplasms, medicine.disease, Organoids, medicine.anatomical_structure, Cancer cell, Cancer research, Colorectal Neoplasms, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9a42556304468029dfc61938e3bc42
https://doi.org/10.3791/62630

المؤلفون: Tim Maughan, Owen J. Sansom, Philip D Dunne, James Jackson, Baharak Ahmaderaghi, Andrew S Campbell, Raheleh Amirkhah, Tamsin R M Lannagan, Simon J. Leedham, Kathryn Gilroy, Mark Lawler, Sudhir B Malla, Keara Redmond

مصطلحات موضوعية: education.field_of_study, User Friendly, Software, Resource (project management), business.industry, Analytics, Interface (computing), Genetically Engineered Mouse, Data quality, Population, business, education, Data science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::129c317c242d8c94d93be2b2ee0c90a6
https://doi.org/10.1101/2021.08.12.456127

المؤلفون: Martin Lewis, Simon A. Koblar, Paul Q. Thomas, Susan L. Woods, Atsushi Enomoto, Ryota Ando, Nobumi Suzuki, Tongtong Wang, Krystyna A. Gieniec, Josephine A. Wright, Tamsin R M Lannagan, Laura Vrbanac, Jia Q Ng, Daniel L. Worthley, Hiroki Kobayashi, Mari Ichinose

المصدر: Development (Cambridge, England)
article-version (VoR) Version of Record

مصطلحات موضوعية: Male, 0301 basic medicine, Mouse, Biology, Bone morphogenetic protein, Bone Morphogenetic Protein 1, Mice, 03 medical and health sciences, Glutamatergic, 0302 clinical medicine, Conditional gene knockout, medicine, BMP, Animals, Molecular Biology, Cell Proliferation, Mice, Knockout, Motor Neurons, Neurons, Behavior, Animal, Cortical development, Cerebrum, Stem Cells, Brain, Gene Expression Regulation, Developmental, Cell Differentiation, Fear, Embryonic stem cell, Cell biology, Cortex (botany), Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, embryonic structures, Forebrain, Intercellular Signaling Peptides and Proteins, Neural Development, Grem1, Excitatory neuron, Female, Transcriptome, Gremlin (protein), 030217 neurology & neurosurgery, Research Article, Signal Transduction, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce58a7e32b47dd420adcbb63c87e134
https://doi.org/10.1242/dev.195883

المؤلفون: Tamsin R M Lannagan, Owen J. Sansom, Campbell S.D. Roxburgh, Colin W. Steele, M. Gillespie

المصدر: Oncology Reviews
Oncology Reviews, Vol 15, Iss 1 (2021)

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Cancer Research, Colorectal cancer, neo-adjuvant treatment, medicine.medical_treatment, MEDLINE, Review, chemotherapy, Other systems of medicine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, mouse models, Rectal cancer, organoids, radiotherapy, business.industry, medicine.disease, RC31-1245, Clinical trial, Radiation therapy, Transplantation, 030104 developmental biology, 030220 oncology & carcinogenesis, Genetically Engineered Mouse, Treatment strategy, business, RZ201-999, Chemoradiotherapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b934596b4cc6935f78e120a319b791b3

المؤلفون: Souzaburo Ihara, Yoku Hayakawa, Krystyna A. Gieniec, Tamsin R M Lannagan, Tongtong Wang, Patrick A. Hughes, Josephine A. Wright, Nobumi Suzuki, Susan L. Woods, Jia Q Ng, Daniel L. Worthley, Chris Mavrangelos, Hiroki Kobayashi, Laura Vrbanac, Mari Ichinose

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: 0301 basic medicine, Stromal cell, CD14, medicine.medical_treatment, Science, Inflammation, Biology, Article, Monocytes, Proinflammatory cytokine, 03 medical and health sciences, Mice, 0302 clinical medicine, Enterocolitis, Necrotizing, medicine, Animals, Humans, Gene Regulatory Networks, Cells, Cultured, Multidisciplinary, Infant, Newborn, Intestinal epithelium, Coculture Techniques, Cell biology, Infant necrotizing enterocolitis, Intestines, Mice, Inbred C57BL, 030104 developmental biology, Cytokine, 030220 oncology & carcinogenesis, TLR4, Medicine, medicine.symptom, Stromal Cells, Transcriptome, Ex vivo, Infant, Premature

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc89aa14612a14cab4cafd2af48b4cee
http://europepmc.org/articles/PMC8010037

المؤلفون: Tamsin R M Lannagan, Prashanthi Ramesh, Owen J. Sansom, Rene Jackstadt, Jan Paul Medema, Geert J. P. L. Kops, Lidia Atencia Taboada, Sanne M. van Neerven, Aleksandar Buryanov Kirov, Pratyaksha Wirapati, Sabine Tejpar, Danielle Dekker, Jessica Pritchard, Nico Lansu, Sander R. van Hooff

المساهمون: Center of Experimental and Molecular Medicine, Graduate School, AII - Cancer immunology, CCA - Cancer biology and immunology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Radiotherapy, Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Cell Death and Differentiation
Cell death and differentiation, 28(12), 3282-3296. Nature Publishing Group
Cell Death and Differentiation, 28(12), 3282-3296. Nature Publishing Group

مصطلحات موضوعية: HUMAN COLON, EXPRESSION, Adenoma, Male, Biochemistry & Molecular Biology, Cell biology, Colorectal cancer, bcl-X Protein, Bcl-xL, Apoptosis, MYC, medicine.disease_cause, Article, Mice, Downregulation and upregulation, microRNA, medicine, Animals, Humans, MCL1, Cancer models, Molecular Biology, Science & Technology, biology, MUTATIONS, Cancer stem cells, INHIBITOR, Cancer, Cell Biology, medicine.disease, GENE, Survival Analysis, APOPTOSIS, POLYPOSIS, TARGET, biology.protein, Cancer research, Disease Progression, Female, Stem cell, Carcinogenesis, Colorectal Neoplasms, Life Sciences & Biomedicine, STEM-CELLS

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0895e238a86f343e3725f5f1dd7549
https://pubmed.ncbi.nlm.nih.gov/34117376