المؤلفون: Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca Jarvis, Wesley Blackaby, Ovadia Lazari, Liudvikas Urbonas, Maria Eznarriaga, Rachel Williams, Annelieke Strijbosch, Rhea Van de Bospoort, Kim Matthews, Cole Clissold, Tammy Ladduwahetty, Huw Vater, Patrick Heaphy, Douglas G. Stafford, Hong-Jun Wang, John E. Mangette, George McAllister, Vahri Beaumont, Thomas F. Vogt, Hilary A. Wilkinson, Elizabeth M. Doherty, Celia Dominguez

المصدر: Journal of medicinal chemistry. 65(18)

مصطلحات موضوعية: Neurons, Disease Models, Animal, Huntingtin Protein, Mice, Huntington Disease, Drug Development, Drug Discovery, Proteolysis, Molecular Medicine, Animals, Ubiquitins, Histone Deacetylases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9b7293f23145d9276a05495bc08822
https://pubmed.ncbi.nlm.nih.gov/36098485

المؤلفون: Yiman Liu, Qinglan Li, Fatemeh Alikarami, Declan R. Barrett, Leila Mahdavi, Hangpeng Li, Sylvia Tang, Tanweer A. Khan, Mayako Michino, Connor Hill, Lele Song, Lu Yang, Yuanyuan Li, Sheela Pangeni Pokharel, Andrew W. Stamford, Nigel Liverton, Louis M. Renzetti, Simon Taylor, Gillian F. Watt, Tammy Ladduwahetty, Stacia Kargman, Peter T. Meinke, Michael A. Foley, Junwei Shi, Haitao Li, Martin Carroll, Chun-Wei Chen, Alessandro Gardini, Ivan Maillard, David J. Huggins, Kathrin M. Bernt, Liling Wan

المصدر: Cancer Discovery. 12:2684-2709

مصطلحات موضوعية: Histones, Leukemia, Myeloid, Acute, Oncology, Lysine, Humans, Chromatin, Myeloid-Lymphoid Leukemia Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5fcfb855331239cbc7d1400995ed4d
https://doi.org/10.1158/2159-8290.cd-21-1307

المؤلفون: Liling Wan, Kathrin M. Bernt, David J. Huggins, Ivan Maillard, Alessandro Gardini, Chun-Wei Chen, Martin Carroll, Haitao Li, Junwei Shi, Michael A. Foley, Peter T. Meinke, Stacia Kargman, Tammy Ladduwahetty, Gillian F. Watt, Simon Taylor, Louis M. Renzetti, Nigel Liverton, Andrew W. Stamford, Sheela Pangeni Pokharel, Yuanyuan Li, Lu Yang, Lele Song, Connor Hill, Mayako Michino, Tanweer A. Khan, Sylvia Tang, Hangpeng Li, Leila Mahdavi, Declan R. Barrett, Fatemeh Alikarami, Qinglan Li, Yiman Liu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0e032c6cb527a071007d7e437dfd6e
https://doi.org/10.1158/2159-8290.22541677.v1

المؤلفون: Liling Wan, Kathrin M. Bernt, David J. Huggins, Ivan Maillard, Alessandro Gardini, Chun-Wei Chen, Martin Carroll, Haitao Li, Junwei Shi, Michael A. Foley, Peter T. Meinke, Stacia Kargman, Tammy Ladduwahetty, Gillian F. Watt, Simon Taylor, Louis M. Renzetti, Nigel Liverton, Andrew W. Stamford, Sheela Pangeni Pokharel, Yuanyuan Li, Lu Yang, Lele Song, Connor Hill, Mayako Michino, Tanweer A. Khan, Sylvia Tang, Hangpeng Li, Leila Mahdavi, Declan R. Barrett, Fatemeh Alikarami, Qinglan Li, Yiman Liu

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dda37f869094a53ad62552e6a254079
https://doi.org/10.1158/2159-8290.c.6549718

المؤلفون: Tammy Ladduwahetty, Matthew R. Lee, Michel C. Maillard, Roger Cachope, Daniel Todd, Michael Barnes, Vahri Beaumont, Alka Chauhan, Caroline Gallati, Alan F. Haughan, Georg Kempf, Christopher A. Luckhurst, Kim Matthews, George McAllister, Philip Mitchell, Hiral Patel, Mark Rose, Elizabeth Saville-Stones, Stefan Steinbacher, Andrew J. Stott, Emma Thatcher, Jason Tierney, Liudvikas Urbonas, Ignacio Munoz-Sanjuan, Celia Dominguez

المصدر: Journal of medicinal chemistry. 65(14)

مصطلحات موضوعية: Disease Models, Animal, Huntingtin Protein, Mice, rho-Associated Kinases, Huntington Disease, Drug Discovery, Molecular Medicine, Animals, Brain, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828c256846fb4f8cb363fd87248c71f6
https://pubmed.ncbi.nlm.nih.gov/35816678

المؤلفون: Gavin Bennett, Anne J. Rüger, John Thomas Feutrill, Rosemary Lynch, Ann Lewis, Anthea L. Newton, Nico Zinn, Tammy Ladduwahetty, Sunose Mihiro, Andrew Cansfield, Giovanna Bergamini, Oliver Rausch, Alan P. Watt, Douglas W. Thomson, Katie Ellard

المصدر: ACS Medicinal Chemistry Letters. 7:768-773

مصطلحات موضوعية: 0301 basic medicine, Kinase, Organic Chemistry, Arthritis, Inflammation, Pharmacology, Biology, medicine.disease, Biochemistry, In vitro, 03 medical and health sciences, 030104 developmental biology, In vivo, Drug Discovery, medicine, Phosphorylation, medicine.symptom, PI3K/AKT/mTOR pathway, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c737c2b53bd2e69fa1983934fa60781
https://doi.org/10.1021/acsmedchemlett.6b00149