يعرض 1 - 13 نتائج من 13 نتيجة بحث عن '"TUDCA, Tauroursodeoxycholic acid"', وقت الاستعلام: 0.52s تنقيح النتائج
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    المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
    Cellular and Molecular Gastroenterology and Hepatology

    مصطلحات موضوعية: 0301 basic medicine, Gut Dysbiosis, OST-β, organic solute transporter subunit-β, SQSTM1, sequestosome-1, FGF15, CK19, cytokeratin 19, Gut flora, FEX, fexaramine, SHP, small heterodimer partner, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, AST, aspartate transaminase, MCA, muricholic acid, CYP8B1, cytochrome p450 family 8b1, BLU, Blu-9931, TCDCA, taurochenodeoxycholic acid, Original Research, FGFR4, fibroblast growth factor receptor 4, TBA, total bile acid, Liver injury, CA, cholic acid, biology, Bile acid, Gastroenterology, qRT-PCR, quantitative real-time polymerase chain reaction, Liver, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, NRF2, nuclear factor erythroid 2-related factor 2, BA, bile acid, 030211 gastroenterology & hepatology, TDCA, taurodeoxycholic acid, medicine.drug, medicine.medical_specialty, GM, gut microbiota, ALT, alanine transaminase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, IBABP, ileal bile acid-binding protein, OST-α, organic solute transporter subunit-α, Liver Injury, ASBT (SLC10A2), apical sodium–bile acid transporter, CDCA, chenodeoxycholic acid, Bile Acids and Salts, CYP7A1, cytochrome p450 7a1, 03 medical and health sciences, FXR, farnesoid X receptor, ATG, autophagy-related gene, TUDCA, tauroursodeoxycholic acid, Internal medicine, medicine, Autophagy, BAS, bile acid sequestrants, lcsh:RC799-869, Cholestyramine, ALP, alkaline phosphatase, FGF15, fibroblast growth factor 15, SE, standard error, Hepatology, Fibroblast growth factor receptor 4, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, PCoA, principal coordinates analysis, BSH, bile salt hydrolase, ABX, antibiotics, TLCA, taurolithocholic acid, TMCA, tauromuricholic acid, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease

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    المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 19-32 (2020)
    Acta Pharmaceutica Sinica. B

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    المساهمون: Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 (GRITA), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Recherche translationnelle sur le diabète - U 1190 (RTD), University of Antwerp (UA), Antwerp University Hospital [Edegem] (UZA), ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016), European Project: 32591,HEPADIP, European Project: 305707,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,RESOLVE(2013), Derudas, Marie-Hélène, PreciNASH - - PreciNASH2016 - ANR-16-RHUS-0006 - RHUS - VALID, EGID Diabetes Pole - - EGID2010 - ANR-10-LABX-0046 - LABX - VALID, Bile acid, immune-metabolism, lipid and glucose homeostasis - ImmunoBile - - H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) 2016-09-01 - 2021-08-31 - 694717 - VALID, Hepatic and adipose tissue and functions in the metabolic syndrome - HEPADIP - 32591 - OLD, A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities, hypertriglyceridemia and low HDL-cholesterol - RESOLVE - - EC:FP7:HEALTH2013-01-01 - 2017-12-31 - 305707 - VALID, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille

    المصدر: JHEP Reports Innovation in Hepatology
    JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
    JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
    JHEP Reports
    JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)

    مصطلحات موضوعية: GHDCA, glycolithocholic acid, taurohyodeoxycholic acid, OGTT, oral glucose tolerance test, GUDCA, glycoursodeoxycholic acid, TCDCA, FXR, farnesoid-X-receptor, UDCA, ADA, American Diabetes Association, IR, insulin resistance, GCA, glycocholic acid, THDCA, taurohyodeoxycholic acid, HCA, T2D, LCA, lithocholic acid, HCA, hyocholic acid, DCA, TCDCA, taurochenodeoxycholic acid, GCDCA, glycochenodeoxycholic acid, LCA, NASH, GCDCA, GHCA, glycohyocholic acid, TCA, cholic acid, [SDV] Life Sciences [q-bio], FPG, glycoursodeoxycholic acid, FXR, deoxycholic acid, glycocholic acid, non-alcoholic steatohepatitis, TDCA, taurodeoxycholic acid, HbA1c, NASH, non-alcoholic steatohepatitis, T2D, type 2 diabetes, Translational study, oral glucose tolerance test, digestive system, BA, UDCA, ursodeoxycholic acid, HDCA, glycochenodeoxycholic acid, TUDCA, tauroursodeoxycholic acid, NAFLD, OGTT, taurochenodeoxycholic acid, NAFL, non-alcoholic fatty liver, GCA, FPG, fasting plasma glycaemia, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, C4, bile acids, glycodeoxycholic acid, nutritional and metabolic diseases, HOMA2, homeostatic model assessment 2, hyocholic acid, digestive system diseases, farnesoid-X-receptor, DCA, deoxycholic acid, GUDCA, IR, TLCA, taurolithocholic acid, American Diabetes Association, CDCA, Human medicine, ABOS, Biological Atlas of Severe Obesity, HDCA, hyodeoxycholic acid, [SDV]Life Sciences [q-bio], HOMA2, taurodeoxycholic acid, taurolithocholic acid, C4, 7alpha-hydroxy-4-cholesten-3-one, insulin resistance, Biological Atlas of Severe Obesity, taurohyocholic acid, MAFLD, metabolic associated fatty liver disease, CA, cholic acid, CA, THCA, GHDCA, glycohyodeoxycholic acid, Diabetes, TLCA, glycohyocholic acid, ursodeoxycholic acid, TUDCA, TDCA, fasting plasma glycaemia, lithocholic acid, NAFL, BA, bile acids, chenodeoxycholic acid, non-alcoholic fatty liver, type 2 diabetes, ABOS, Research Article, NAFLD, non-alcoholic fatty liver disease, TCA, taurocholic acid, MAFLD, taurocholic acid, CDCA, chenodeoxycholic acid, metabolic associated fatty liver disease, glycated haemoglobin, homeostatic model assessment 2, Obesity, lcsh:RC799-869, tauroursodeoxycholic acid, 7alpha-hydroxy-4-cholesten-3-one, non-alcoholic fatty liver disease, THDCA, hyodeoxycholic acid, ADA, GDCA, lcsh:Diseases of the digestive system. Gastroenterology, HbA1c, glycated haemoglobin, GHCA, glycohyodeoxycholic acid, THCA, taurohyocholic acid, GLCA

    وصف الملف: application/pdf

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    المصدر: Pancreas

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    المصدر: The Journal of Biological Chemistry

    مصطلحات موضوعية: 0301 basic medicine, WT, wild type, obesity, medicine.medical_treatment, immunometabolism, Adipose tissue, Hormone-sensitive lipase, White adipose tissue, Biochemistry, TKI, tyrosine kinase inhibitor, TLR4, toll-like receptor 4, Mice, PVDF, polyvinylidene difluoride, chemistry.chemical_compound, UPR, unfolded protein response, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, HSL, hormone sensitive lipase, Adipocyte, Adipocytes, cytokine, Insulin, SVF, stromal vascular fraction, FK565, heptanoyl-γ-D-glutamyl-L-meso-diamino-pimelyl-D-alanine, Phosphorylation, ABL, Abelson murine leukemia viral oncogene homolog, TNF, tumor necrosis factor, 0303 health sciences, Grp78/BiP, binding immunoglobulin protein or heat shock 70 kDa protein 5, biology, PGN, peptidoglycan, Chemistry, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, NF-kappa B, WAT, white adipose tissue, BMDM, bone-marrow-derived macrophage, Il(6), interleukin, XBP1, X-box binding protein 1, Adipose Tissue, Cytokines, LPS, lipopolysaccharide, ER stress, SEAP, secreted alkaline phosphatase, Signal Transduction, Research Article, Proto-oncogene tyrosine-protein kinase Src, AKO, adipose knockout, medicine.medical_specialty, ATF6, activating transcription factor 6, Lipolysis, IRE1, inositol-requiring enzyme 1, Protein Serine-Threonine Kinases, CHOP, C/EBP homologous protein, adipocyte, metabolic syndrome, 8-Br-cAMP, 8-bromoadenosine 3′,5′-cyclic monophosphate, ER, endoplasmic reticulum, endocrinology, HEK, human embryonic kidney, 03 medical and health sciences, Insulin resistance, lipid, 3T3-L1 Cells, TUDCA, tauroursodeoxycholic acid, Internal medicine, medicine, Animals, 4-PBA, 4-phenylbutyric acid, RIPK2, receptor interacting serine/threonine kinase 2, Kinase activity, Molecular Biology, Protein kinase B, 030304 developmental biology, Inflammation, ATGL, adipose triglyceride lipase, 030102 biochemistry & molecular biology, Macrophages, Membrane Proteins, Cell Biology, medicine.disease, Insulin receptor, 030104 developmental biology, PERK, protein kinase RNA-like ER kinase, Endocrinology, KirA6, IRE1α kinase inhibiting RNase attenuator 6, Akt, protein kinase B, biology.protein, Unfolded protein response, PKA, protein kinase A, Insulin Resistance, NOD, nucleotide-binding oligomerization domain-containing protein, 030217 neurology & neurosurgery

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    المصدر: Molecular Metabolism
    Molecular Metabolism, Vol 15, Iss, Pp 70-81 (2018)

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    المصدر: Molecular metabolism 22, 96-109 (2019). doi:10.1016/j.molmet.2019.01.012
    Molecular Metabolism
    Molecular Metabolism, Vol 22, Iss, Pp 96-109 (2019)
    Mol. Metab. 22, 96-109 (2019)

    مصطلحات موضوعية: 0301 basic medicine, Male, Synbiotics, medicine.medical_treatment, Mice, Obese, Gut flora, TNF-α, tumor necrosis factor-α, law.invention, DCA, Deoxycholic acid, ωMCA, ω-Muricholic acid, Probiotic, Mice, 0302 clinical medicine, αMCA, α-Muricholic acid, law, TCA, Taurocholic acid, Food science, biology, TUDCA, Tauroursodeoxycholic acid, food and beverages, UDCA, Ursodeoxycholic acid, LBP, lipopolysaccharide-binding protein, Bifidobacterium animalis, ddc, LCA, Lithocholic acid, High-fat diet, MCP-1, monocyte chemotactic protein 1, Original Article, lcsh:Internal medicine, Lactobacillus paracasei, Normal diet, Dietary Intervention, Gut Microbiota, High-fat Diet, Obesity, 030209 endocrinology & metabolism, Gut microbiota, TCDCA, Taurochenodeoxycholic acid, Diet, High-Fat, SCFAs, short-chain fatty acids, THDCA, Taurohyodeoxycholic acid, 03 medical and health sciences, 7-oxoDCA, 7-oxodeoxycholic acid, medicine, βTMCA, β-Tauromuricholic acid, Animals, MDCA, Murideoxycholic acid, lcsh:RC31-1245, Molecular Biology, CA-7S, Cholic acid 7-sulfate, ωTMCA, ω-Tauromuricholic acid, Prebiotic, BAs, bile acids, αTMCA, α-Tauromuricholic acid, βMCA, β-Muricholic acid, Cell Biology, eAT, epididymal adipose tissue, biology.organism_classification, HDCA, Hyodeoxycholic acid, Gastrointestinal Microbiome, Mice, Inbred C57BL, Dietary intervention, 030104 developmental biology, CA, Cholic acid, alloCA, Allocholic acid, 3-dehydroCDCA, 3-dehydrochenodeoxycholic acid, Diet-induced obese, TDCA, Taurodeoxycholic acid

    وصف الملف: application/pdf

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    المؤلفون: Amanda R. Arnold, Benoit Chassaing

    المصدر: Cellular and Molecular Gastroenterology and Hepatology

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    المصدر: Bai, Peng; Ye, Haifeng; Xie, Mingqi; Saxena, Pratik; Zulewski, Henryk; Charpin-El Hamri, Ghislaine; Djonov, Valentin; Fussenegger, Martin (2016). A synthetic biology-based device prevents liver injury in mice. Journal of hepatology, 65(1), pp. 84-94. Elsevier 10.1016/j.jhep.2016.03.020 <http://dx.doi.org/10.1016/j.jhep.2016.03.020>
    Journal of Hepatology
    Journal of Hepatology, 65 (1)

    وصف الملف: application/pdf; application/application/pdf

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    المصدر: Molecular Aspects of Medicine

    مصطلحات موضوعية: PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha, FXR, farnesoid X receptor (NR1H4), HNF4α, hepatocyte nuclear factor 4 alpha, CARM1, co-activator-associated arginine methyltransferase 1, OATP, organic anion transporting polypeptide, VDR (NR1I1), vitamin D receptor, Review, BCRP (ABCG2), breast cancer resistance protein, NDRG2, NMYC downstrean-regulated gene 2, MRP4 (ABCC4), multidrug resistance-associated protein 4, SRC2, steroid receptor co-activator 2, GGT, gamma-glutamyl transpeptidase, MDR1 (ABCB1), multidrug resistance protein 1, Nuclear receptors, GRE, glucocorticoid response element, CtBP, C-terminal binding protein, GCA, glycocholic acid, TβMCA, β-tauromuricholic acid, TNF-α, tumor necrosis factor alpha, ATB-binding cassette transporters, FGF19/FGF15, fibroblast growth factor 19/15, MARE, MAF recognition element, ATP Binding Cassette Transporter, Subfamily B, Member 11, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, Cholestasis, ASBT (SLC10A2), apical sodium-dependent bile acid transporter, Symporters, AE2 (SLC4A2), anion exchanger 2, ABC, ATP-binding cassette, FXRE, FXR response element, cAMP, cyclic adenosine monophosphate, DILI, drug-induced liver injury, IL-6, interleukin 6, PL, phospholipid, TGR5, G protein coupled bile acid receptor, OCA, obeticholic acid, OSTα/OSTβ (SLC51A/SLC51B), organic solute transporter alpha/beta, LRH1 (NR5A2), liver receptor homologue 1, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, LPS, lipopolysaccharide, BRIC2, benign recurrent intrahepatic cholestasis type 2, LXR (NR1H3), liver X receptor, Transcriptional Activation, PFIC2, progressive familial intrahepatic cholestasis type 2, PXR (NR1I2), pregnane X receptor, TCA, taurocholic acid, RXRα (NR2B1), retinoid X receptor, Organic Anion Transporters, Sodium-Dependent, CCl4, carbone tetrachloride, UDCA, ursodeoxycholic acid, Bile Acids and Salts, CDCA, chenodeoxycholic acid, STAT-5, signal transducer and activator of transcription 5, LCA, litocholic acid, ALT, alanine aminotransferase, CBDL, common bile duct ligation, IR-1, inverse repeat 1, TUDCA, tauroursodeoxycholic acid, Humans, ICP, intrahepatic cholestasis of pregnancy, GR (NR3C1), glucocorticoid receptor, MRP2 (ABCC2), multidrug resistance-associated protein 2, TαMCA, α-tauromuricholic acid, TPN, total parenteral nutrition, ALP, alkaline phosphatase, IL-1β, interleukin-1 beta, SREBP1, sterol regulatory element-binding protein 1, Membrane Transport Proteins, Biological Transport, BSEP (ABCB11), bile salt export pump, MAF, musculo-aponeurotic fibrosacroma, ASCOM, activating signal cointegrator-2-containing complex, HNF1α, hepatocyte nuclear factor 1 alpha, MCL-1, myeloid cell leukemia factor 1, NTCP (SLC10A1), Na+-taurocholate cotransporting polypeptide solute carrier family 10 member 1, VPAC-1, vasoactive intestinal polypeptide activated receptor, AMPK, AMP-activated protein kinase, MRP3 (ABCC3), multidrug resistance-associated protein 3, NF-κB, nuclear factor kappa-B, PSC, primary sclerosing cholangitis, Gene Expression Regulation, DCA, deoxycholic acid, BS, bile salt, MDR2 (ABCB4), multidrug resistance protein 2, PPARα (NR1C1), peroxisome proliferator-activated receptor alpha, SHP (NR0B2), short heterodimer partner, RARα (NR1B1), retinoic acid receptor, ATP-Binding Cassette Transporters, PBC, primary biliary cirrhosis, PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma

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    المصدر: ASN NEURO
    ASN Neuro, Vol 2 (2010)

    مصطلحات موضوعية: Male, DCF, 2′,7′-dichlorodihydrofluorescein, Connexin, Cell Communication, medicine.disease_cause, Connexins, Rats, Sprague-Dawley, dBcAMP, dibutyryl cAMP, DIC, differential interference contrast, NOS, nitric oxide synthase, Cells, Cultured, DMEM, Dulbecco's modified Eagle's medium, diabetes, General Neuroscience, NA, numerical aperture, Gap junction, Gap Junctions, LYCH, Lucifer Yellow CH, Connexin 26, aCSF, artificial cerebrospinal fluid, medicine.anatomical_structure, medicine.drug, Astrocyte, Research Article, medicine.medical_specialty, Cell signaling, Central nervous system, Biology, S8, 6-NBDG, 6-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxyglucose, streptozotocin, STZ, streptozotocin, TMAO, trimethylamine N-oxide dihydrate, S5, lcsh:RC321-571, Diabetes Mellitus, Experimental, gap junction, ER, endoplasmic reticulum, RNS, reactive nitrogen species, astrocyte, ROS, reactive oxygen species, FBS, fetal bovine serum, Internal medicine, Diabetes mellitus, TUDCA, tauroursodeoxycholic acid, PKC, protein kinase C, medicine, 4-PBA, 4-phenylbutyric acid, Animals, Cx, connexin, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, l-NAME, l-Nω-nitro-l-arginine methyl ester, Streptozotocin, medicine.disease, MnTBAP, manganese(III) tetrakis (4-benzoic acid) porphyrin chloride, Rats, LYVS, Lucifer Yellow VS, Oxidative Stress, Endocrinology, connexin (Cx), Astrocytes, Hyperglycemia, carboxy-DCF-DA, carboxy DCF diacetate, Neurology (clinical), Oxidative stress, hyperglycaemia