المؤلفون: Abdelkader Daoud, Sunny Xia, Onofrio Laselva, Janet Jiang, Christine E. Bear

المصدر: Stem Cell Research, Vol 83, Iss , Pp 103653- (2025)

مصطلحات موضوعية: Cystic fibrosis, iPSC-derived colonic organoids, TRIKAFTA, Biology (General), QH301-705.5

Relation: http://www.sciencedirect.com/science/article/pii/S1873506125000030; https://doaj.org/toc/1873-5061; https://doaj.org/article/2ee8b19e2f834cd5b68f8974c8a15f06

الاتاحة: https://doi.org/10.1016/j.scr.2025.103653
https://doaj.org/article/2ee8b19e2f834cd5b68f8974c8a15f06

المؤلفون: Areeba Akram, Azra Sakhawat, Muhammad Usman Ghani, Muhammad Umer Khan, Raima Rehman, Qurban Ali, Peng Jin-liang, Daoud Ali

المصدر: AMB Express, Vol 14, Iss 1, Pp 1-18 (2024)

مصطلحات موضوعية: Cystic fibrosis, Trikafta, Mutation, Molecular docking molecular simulation, ADMET, Biotechnology, TP248.13-248.65, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2191-0855

URL الوصول: https://doaj.org/article/3e115058162e4d33b1715c471ef6b5f6

المؤلفون: Stefania Lo Cicero, Germana Castelli, Giovanna Blaconà, Sabina Maria Bruno, Giovanni Sette, Riccardo Pigliucci, Valeria Rachela Villella, Speranza Esposito, Immacolata Zollo, Francesca Spadaro, Ruggero De Maria, Mauro Biffoni, Giuseppe Cimino, Felice Amato, Marco Lucarelli, Adriana Eramo

المصدر: Respiratory Research, Vol 24, Iss 1, Pp 1-20 (2023)

مصطلحات موضوعية: Cystic fibrosis, CFTR, Reprogrammed nasal cells, Nasal organoids, ALI culture, Trikafta, Diseases of the respiratory system, RC705-779

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1465-993X

URL الوصول: https://doaj.org/article/b4d7cae7df80409786f2da0722aa6ceb

المؤلفون: Douglas, Lisa E.J., Reihill, James A., Martin, S. Lorraine

المصدر: Douglas , L E J , Reihill , J A & Martin , S L 2024 , ' BOS-318 treatment enhances elexacaftor-tezacaftor-ivacaftor (ETI)-mediated improvements in airways hydration and mucociliary transport ' , ERJ Open Research . https://doi.org/10.1183/23120541.00445-2024

مصطلحات موضوعية: BOS-318, Trikafta, ETI, mucociliary clearance, cystic fibrosis, airways hydration, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

الاتاحة: https://pure.qub.ac.uk/en/publications/8047f2cf-d93c-47e5-88a1-fdaf3c082543
https://doi.org/10.1183/23120541.00445-2024

المؤلفون: Pascarel, Khilian, Colas, Jenny, Carrez, Thomas, Barrault, Christine, Mirval, Sandra, Coraux, Christelle, Sage, Edouard, Becq, Frédéric, Vandebrouck, Clarisse

المساهمون: Physiopathologie et régulation des transports ioniques (PRéTI Poitiers ), Université de Poitiers = University of Poitiers (UP), ManRos Therapeutics, Pathologies Pulmonaires et Plasticité Cellulaire - UMR-S 1250 (P3CELL), Université de Reims Champagne-Ardenne (URCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Virologie et Immunologie Moléculaires (VIM (UR 0892)), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Foch Suresnes

المصدر: ISSN: 2375-1916 ; Medical Research Archives ; https://hal.science/hal-04496971 ; Medical Research Archives, 2024, 12 (2), ⟨10.18103/mra.v12i2.4909⟩ ; https://esmed.org/MRA/mra/article/view/4909.

مصطلحات موضوعية: HIF-1α, cystic fibrosis, human bronchial cells, Trikafta, [SDV]Life Sciences [q-bio]

الاتاحة: https://hal.science/hal-04496971
https://hal.science/hal-04496971v1/document
https://hal.science/hal-04496971v1/file/Pascarel%20et%20al.%202024%20MRA.pdf
https://doi.org/10.18103/mra.v12i2.4909

المؤلفون: Marsh, Ryan, Santos, Claudio Dos, Yule, Alexander, Dellschaft, Neele S, Hoad, Caroline L, Ng, Christabella, Major, Giles, Smyth, Alan R, Rivett, Damian, van der Gast, Christopher

المصدر: Marsh , R , Santos , C D , Yule , A , Dellschaft , N S , Hoad , C L , Ng , C , Major , G , Smyth , A R , Rivett , D & van der Gast , C 2024 , ' Impact of extended Elexacaftor/Tezacaftor/Ivacaftor therapy on the gut microbiome in cystic fibrosis ' , Journal of Cystic Fibrosis , vol. 23 , no. 5 , pp. 967-976 . https://doi.org/10.1016/j.jcf.2024.05.002

مصطلحات موضوعية: CFTR modulator therapy, Pulmonary antibiotics, Dysbiosis, Kaftrio, Gut microbiome, Trikafta

وصف الملف: application/pdf

الاتاحة: https://pure.qub.ac.uk/en/publications/34e1e6f3-6f80-4b6f-813a-ce7eed8a02c8
https://doi.org/10.1016/j.jcf.2024.05.002
https://pureadmin.qub.ac.uk/ws/files/613866272/1-s2.0-S156919932400064X-main.pdf

المؤلفون: Nikiforovs, Abigail

المصدر: Columbia Social Work Review; Vol. 22 No. 1 (2024): Columbia Social Work Review; 74-91 ; 2164-1250 ; 2372-255X

مصطلحات موضوعية: cystic fibrosis, social security, SSI, SSDI, Ohio Social Security, Trikafta, CFTR Modulator

وصف الملف: application/pdf

Relation: https://journals.library.columbia.edu/index.php/cswr/article/view/12193/6264; https://journals.library.columbia.edu/index.php/cswr/article/view/12193

الاتاحة: https://journals.library.columbia.edu/index.php/cswr/article/view/12193

المؤلفون: Miroslaw Zajac, Agathe Lepissier, Elise Dréano, Benoit Chevalier, Aurélie Hatton, Mairead Kelly-Aubert, Daniela Guidone, Gabrielle Planelles, Aleksander Edelman, Emmanuelle Girodon, Alexandre Hinzpeter, Gilles Crambert, Iwona Pranke, Luis. J. V. Galietta, Isabelle Sermet-Gaudelus

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: ion transport across membrane, cystic fibrosis transmembrane conductance regulator, bicarbonate, inflammation, TRIKAFTA, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1293578/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/216815fa6c914e6888231ca2f55b094c

المؤلفون: Jane T. Jones, Kaesi A. Morelli, Elisa M. Vesely, Charles T. S. Puerner, Chetan K. Pavuluri, Brandon S. Ross, Norman van Rhijn, Michael J. Bromley, Robert A. Cramer

المصدر: mBio, Vol 14, Iss 5 (2023)

مصطلحات موضوعية: Aspergillus fumigatus, Trikafta, cystic fibrosis, anti-fungal agents, drug susceptibility, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/098d58ffb46747e4a7339172e4604e5e

المؤلفون: Frauke Stanke, Sophia T. Pallenberg, Stephanie Tamm, Silke Hedtfeld, Ella M. Eichhorn, Rebecca Minso, Gesine Hansen, Tobias Welte, Annette Sauer-Heilborn, Felix C. Ringshausen, Sibylle Junge, Burkhard Tümmler, Anna-Maria Dittrich

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: elexcaftor-tezacaftor-ivacaftor, TRIKAFTA, CFTR protein expression, CFTR glycosylation, CFTR small molecule therapeutics, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1114584/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/7cc5bf37360f4ab5bcfbf6cd9a5992a0

المؤلفون: Michela Capraro, Marco Pedrazzi, Roberta De Tullio, Marcello Manfredi, Federico Cresta, Carlo Castellani, Monica Averna

المصدر: International Journal of Molecular Sciences ; Volume 24 ; Issue 17 ; Pages: 13384

مصطلحات موضوعية: Trikafta ®, NF-kB, ERK1/2, personalized medicine, circulating mononuclear cells (CMCs), cystic fibrosis, biomarker

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms241713384

الاتاحة: https://doi.org/10.3390/ijms241713384

المؤلفون: Nikoletta Kapouni, Maria Moustaki, Konstantinos Douros, Ioanna Loukou

المصدر: Children; Volume 10; Issue 3; Pages: 554

مصطلحات موضوعية: cystic fibrosis, cystic fibrosis transmembrane conductance regulator (CFTR) protein, CFTR modulators, elexacaftor, ivacaftor, tezacaftor, kaftrio, trikafta

وصف الملف: application/pdf

Relation: Pediatric Pulmonary and Sleep Medicine; https://dx.doi.org/10.3390/children10030554

الاتاحة: https://doi.org/10.3390/children10030554

المؤلفون: Mafalda Bacalhau, Mariana Camargo, Grace A. V. Magalhães-Ghiotto, Sybelle Drumond, Carlos Henrique M. Castelletti, Miquéias Lopes-Pacheco

المصدر: Pharmaceuticals; Volume 16; Issue 3; Pages: 410

مصطلحات موضوعية: adverse effects, case report, clinical efficacy, clinical trial, Kaftrio, precision medicine, observational study, real-life study, safety, Trikafta

وصف الملف: application/pdf

Relation: Pharmacology; https://dx.doi.org/10.3390/ph16030410

الاتاحة: https://doi.org/10.3390/ph16030410

المؤلفون: Daichi Hinata, Ryosuke Fukuda, Tsukasa Okiyoneda

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 3; Pages: 2305

مصطلحات موضوعية: CFTR, COPD, polymorphism, cystic fibrosis, IL-8, Trikafta, CFTR modulator

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms24032305

الاتاحة: https://doi.org/10.3390/ijms24032305

المؤلفون: Shogo Taniguchi, Yukiko Ito, Hibiki Kiritani, Asuka Maruo, Ryohei Sakai, Yuji Ono, Ryosuke Fukuda, Tsukasa Okiyoneda

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, cystic fibrosis, CFTR, ubiquitin ligase, peripheral quality control, RFFL, RNF34, Trikafta

Relation: https://figshare.com/articles/presentation/Presentation1_The_Ubiquitin_Ligase_RNF34_Participates_in_the_Peripheral_Quality_Control_of_CFTR_RNF34_Role_in_CFTR_PeriQC_pdf/19327751

الاتاحة: https://doi.org/10.3389/fmolb.2022.840649.s001
https://figshare.com/articles/presentation/Presentation1_The_Ubiquitin_Ligase_RNF34_Participates_in_the_Peripheral_Quality_Control_of_CFTR_RNF34_Role_in_CFTR_PeriQC_pdf/19327751

المؤلفون: Onofrio Laselva, Maria Laura Criscione, Caterina Allegretta, Sante Di Gioia, Arcangelo Liso, Massimo Conese

المصدر: Frontiers in Molecular Biosciences, Vol 9 (2022)

مصطلحات موضوعية: cystic fibrosis, IGFBP-6, airway epithelial cells, dimethyl fumarate, TRIKAFTA, cytokine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.905468/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/6847cf4eaf9646f79f44232024cf0ffa

المؤلفون: Steven Erwood, Onofrio Laselva, Teija M.I. Bily, Reid A. Brewer, Alexandra H. Rutherford, Christine E. Bear, Evgueni A. Ivakine

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 1118-1128 (2020)

مصطلحات موضوعية: genome editing, allele-specificity, TRIKAFTA, cystic fibrosis, CRISPR-Cas9, nonsense-mediated decay, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050120300899; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/eb2405ef414a48d59db42b474b399baf

المؤلفون: Amanda Centorame, Daciana Catalina Dumut, Mina Youssef, Martin Ondra, Irenej Kianicka, Juhi Shah, Radu Alexandru Paun, Tomas Ozdian, John W. Hanrahan, Ekaterina Gusev, Basil Petrof, Marian Hajduch, Radu Pislariu, Juan Bautista De Sanctis, Danuta Radzioch

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: cystic fibrosis, LAU-7b, TRIKAFTA, ceramides, fenretinide (4-HPR), sphingolipids, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.876842/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/e7cbeba9b2d34e6f99a2512513ff9ddf

المؤلفون: Sean A. Aspinall, Kelly A. Mackintosh, Denise M. Hill, Bethany Cope, Melitta A. McNarry

المصدر: International Journal of Environmental Research and Public Health; Volume 19; Issue 10; Pages: 6114

مصطلحات موضوعية: chronic illness, lived experience, qualitative analysis, modulators, trikafta, semi-structured, self-identity, quality of life

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Public Health Statistics and Risk Assessment; https://dx.doi.org/10.3390/ijerph19106114

الاتاحة: https://doi.org/10.3390/ijerph19106114

المؤلفون: Guo, J, Garratt, A, Hill, A

المصدر: 462 ; 456

مصطلحات موضوعية: CFTR modulator, Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, Epidemiology, Ivacaftor/tezacaftor/elexacaftor, Treatment cascade, Trikafta, Respiratory System, 1103 Clinical Sciences

جغرافية الموضوع: Netherlands

Relation: Journal of Cystic Fibrosis; http://hdl.handle.net/10044/1/96752

الاتاحة: http://hdl.handle.net/10044/1/96752
https://doi.org/10.1016/j.jcf.2022.01.009