المؤلفون: Ian G. Cowell, Caroline A. Austin

المصدر: FEBS Open Bio, Vol 14, Iss 6, Pp 1001-1010 (2024)

مصطلحات موضوعية: DNA damage, etoposide, myeloperoxidase, myelotoxicity, TOP2, topoisomerase, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2211-5463

URL الوصول: https://doaj.org/article/6b305dc1b9fd4dc39242da1610c4d130

المؤلفون: Keiko Morotomi-Yano, Ken-ichi Yano

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 19, p 10681 (2024)

مصطلحات موضوعية: aclarubicin, DNA topoisomerase II, TOP2 inhibitor, live cell imaging, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/19/10681; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/bcd69b514f4d41a7923073093ea079a8

الاتاحة: https://doi.org/10.3390/ijms251910681
https://doaj.org/article/bcd69b514f4d41a7923073093ea079a8

المؤلفون: Swanston, Amy

المساهمون: Ferreira, Helder

مصطلحات موضوعية: 572, Molecular biology, Cell biology, Top2, Uls1, Topoisomerase, Chromatin remodelling, Chromatin remodeller, Chromatin, DNA, SUMO, Yeast, Protein modification, Acriflavine, Top2 poison, Drug screen, Genetic screen, Chromatin immunoprecipitation, ChIP-seq, Bioinformatics, QP616.D56S8, DNA topoisomerase II, Adenosine triphosphatase, Saccharomyces cerevisiae

URL الوصول: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.773415

المؤلفون: Choudhary R, Niska-Blakie J, Adhil M, Liberi G, Achar YJ, Giannattasio M, Foiani M

المساهمون: R. Choudhary, J. Niska-Blakie, M. Adhil, G. Liberi, Y. Achar, M. Giannattasio, M. Foiani

مصطلحات موضوعية: CP: Molecular biology, DNA topology, RNPII, Rrm3, Senataxin, Top1, Top2, replication termination, telomere, Settore BIO/11 - Biologia Molecolare, Settore BIO/18 - Genetica, Settore BIO/13 - Biologia Applicata

Relation: info:eu-repo/semantics/altIdentifier/pmid/37405920; info:eu-repo/semantics/altIdentifier/wos/WOS:001031822300001; volume:42; issue:7; firstpage:1; lastpage:23; numberofpages:23; journal:CELL REPORTS; https://hdl.handle.net/2434/985268; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85164355509

الاتاحة: https://hdl.handle.net/2434/985268
https://doi.org/10.1016/j.celrep.2023.112747

المؤلفون: Maria E. Stefanova, Elizabeth Ing-Simmons, Stefan Stefanov, Ilya Flyamer, Heathcliff Dorado Garcia, Robert Schöpflin, Anton G. Henssen, Juan M. Vaquerizas, Stefan Mundlos

المصدر: Cells; Volume 12; Issue 15; Pages: 2001

مصطلحات موضوعية: Hi-C, Top2, doxorubicin, chemotherapy, DSBs, promoters

وصف الملف: application/pdf

Relation: Cellular Pathology; https://dx.doi.org/10.3390/cells12152001

الاتاحة: https://doi.org/10.3390/cells12152001

المؤلفون: Jeong-Min Park, Huimin Zhang, Litong Nie, Chao Wang, Min Huang, Xu Feng, Mengfan Tang, Zhen Chen, Yun Xiong, Namsoo Lee, Siting Li, Ling Yin, Traver Hart, Junjie Chen

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6545

مصطلحات موضوعية: ZATT, TOP2, etoposide sensitivity, CRISPR screens

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/ijms24076545

الاتاحة: https://doi.org/10.3390/ijms24076545

المؤلفون: Yilun Sun, Eroica Soans, Margarita Mishina, Elena Petricci, Yves Pommier, Karin C. Nitiss, John L. Nitiss

المصدر: Frontiers in Molecular Biosciences, Vol 9 (2022)

مصطلحات موضوعية: Mre11-Rad50-Nbs1 complex, topoisomerase II (TOP2), proteasome, VCP/p97, DNA-protein crosslink (DPC) repair, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.1007064/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/9dd2062ba76a40c2bab5b1138e0535ae

المؤلفون: Syed Moiz Ahmed, Peter Dröge

المصدر: Molecular Oncology, Vol 13, Iss 10, Pp 2062-2078 (2019)

مصطلحات موضوعية: chemotherapy, DNA topology, HMGA2, replication stress, TOP2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

URL الوصول: https://doaj.org/article/9bdee317ac4d4203b3c915708f13d271

المؤلفون: Mahmud, Md Rasel Al, マハムッド, ムハンマド ラセル アル

المساهمون: 篠原, 隆司, 小川, 修, 溝脇, 尚志

مصطلحات موضوعية: Topoisomerase 2(TOP2),, DNA double-strand breaks (DSBs),, Androgen,, Prostate,, Hyperplasia

وصف الملف: application/pdf; text/html

URL الوصول: https://ndlsearch.ndl.go.jp/books/R100000039-I11691961

Degree: 博士(医学) -- Doctor of Medical Science -- 京都大学

المؤلفون: Dokshin, Gregoriy A., Davis, Gregory M., Sawle, Ashley D., Eldridge, Matthew D., Nicholls, Peter K., Gourley, Taylin E., Romer, Katherine A., Molesworth, Luke W., Tatnell, Hannah R., Ozturk, Ahmet R., De Rooij, Dirk G., Hannon, Gregory J., Page, David C., Mello, Craig C., Carmell, Michelle A.

المساهمون: Developmental Biology, Sub Developmental Biology

مصطلحات موضوعية: GCNA, DVC-1, Spartan, SprT, topoisomerase, Top2, Top1, DNA-protein crosslink (DPC) repair, Germ cells

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/409877

الاتاحة: https://dspace.library.uu.nl/handle/1874/409877

المؤلفون: William Gittens, Dominic J Johnson, Rachal M Allison, Timothy Cooper, Holly Thomas, Matt Neale

مصطلحات موضوعية: Top2, Spo11, CC-seq, topoisomerase, topological stress, nucleotide-resolution

Relation: 10779/uos.23474102.v1; https://figshare.com/articles/journal_contribution/A_nucleotide_resolution_map_of_Top2-linked_DNA_breaks_in_the_yeast_and_human_genome/23474102

الاتاحة: https://figshare.com/articles/journal_contribution/A_nucleotide_resolution_map_of_Top2-linked_DNA_breaks_in_the_yeast_and_human_genome/23474102

المؤلفون: Deegan, Thomas, Baxter, Jonathan, Ortiz Bazan, Maria, Yeeles, Joseph T. P., Labib, Karim

المصدر: Deegan , T , Baxter , J , Ortiz Bazan , M , Yeeles , J T P & Labib , K 2019 , ' Pif1-family helicases support fork convergence during DNA replication termination in eukaryotes ' , Molecular Cell , vol. 74 , no. 2 , pp. 231-244.e9 . https://doi.org/10.1016/j.molcel.2019.01.040

مصطلحات موضوعية: CMG helicase, DNA replication termination, Pif1, Rrm3, Top2, chromosome replication, fork convergence, replisome, topoisomerase, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/12002532-f1cc-4755-87c9-4f76b4a1aa91
https://doi.org/10.1016/j.molcel.2019.01.040
https://discovery.dundee.ac.uk/ws/files/32694856/1_s2.0_S1097276519300607_main_1_.pdf
http://www.scopus.com/inward/record.url?scp=85064161387&partnerID=8YFLogxK

المؤلفون: Lee, Wang

المصدر: Genes; Volume 10; Issue 11; Pages: 884

مصطلحات موضوعية: topoisomerase, Top3β, Top2, heterochromatin, transposon, aging, disease

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes10110884

الاتاحة: https://doi.org/10.3390/genes10110884

المؤلفون: Naomi Atkin, Heather Raimer, Yuh-Hwa Wang

المصدر: Genes; Volume 10; Issue 10; Pages: 791

مصطلحات موضوعية: DNA topoisomerases, DNA fragility, chromatin organization, TOP2 cleavage complex, topoisomerases and disease, DNA repair

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes10100791

الاتاحة: https://doi.org/10.3390/genes10100791

المؤلفون: Caroline A. Austin, Ka C. Lee, Rebecca L. Swan, Mushtaq M. Khazeem, Catriona M. Manville, Peter Cridland, Achim Treumann, Andrew Porter, Nick J. Morris, Ian G. Cowell

المصدر: International Journal of Molecular Sciences; Volume 19; Issue 9; Pages: 2765

مصطلحات موضوعية: Topoisomerase II, TOP2, Cell cycle, cell biology, transcription, review

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms19092765

الاتاحة: https://doi.org/10.3390/ijms19092765

المؤلفون: Ka Cheong Lee, Rebecca L. Swan, Zbyslaw Sondka, Kay Padget, Ian G. Cowell, Caroline A. Austin

المصدر: International Journal of Molecular Sciences; Volume 19; Issue 7; Pages: 2056

مصطلحات موضوعية: topoisomerase II (TOP2), 5′-tyrosyl DNA phosphodiesterase 2 (TDP2), etoposide, proteasome, TOP2-DNA covalent complex, TARDIS, SUMO

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms19072056

الاتاحة: https://doi.org/10.3390/ijms19072056

المؤلفون: Joshi, Ricky S., Nikolaou, Christoforos, Roca, Joaquim

المساهمون: Ministerio de Economía y Competitividad (España), Nikolaou, Christoforos, Roca, Joaquim

مصطلحات موضوعية: Top1, Top2, DNA transcription, Epigenetics, Gene promoter, Chromatin structure, S. cerevisiae

Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2015-67007-P; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MDM-2014-0435-02; Publisher's version; https://doi.org/10.3390/ijms19010134; Sí; International Journal of Molecular Sciences 19(1): 134 (2018); http://hdl.handle.net/10261/174223; http://dx.doi.org/10.13039/501100003329

الاتاحة: http://hdl.handle.net/10261/174223
https://doi.org/10.3390/ijms19010134
https://doi.org/10.13039/501100003329

المؤلفون: Jan Winter, Chidiebere U. Awah, Markella Zannikou, Denise M. Scholtens, Regina T. Martuscello, Edgar Gonzalez-Buendia, Li Chen, Patrick D. Hsu, Silvana Konerman, Atique Ahmed, Roger Stupp, Daniel Zhang, Dou Yu, Irina V. Balyasnikova, Louisa Warnke, Mukesh Bansal, Balázs Győrffy, Cheol Park, Kirsten Bell Burdett, Adam M. Sonabend, Meeki Lad, Aayushi Mahajan, Eric Feldstein

المصدر: Oncogene
Oncogene, vol 39, iss 27

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA Repair, Protein Synthesis, Double-Stranded, Gene Knockout Techniques, 0302 clinical medicine, Topoisomerase II Inhibitors, DNA Breaks, Double-Stranded, Etoposide, Cancer, Tumor, biology, Brain Neoplasms, Topoisomerase II poisons (TOP2: etoposide, doxorubicin), 030220 oncology & carcinogenesis, CRISPR, Biotechnology, medicine.drug, Ribosomal Proteins, DNA damage, DNA damage and repair response, Protein subunit, Clinical Sciences, Oncology and Carcinogenesis, Type II, Article, Cell Line, 03 medical and health sciences, Rare Diseases, APAF1, Ribosomal protein, Glioma, Glioblastoma (GBM), Cell Line, Tumor, Genetics, medicine, ƴH2AX (gamma H2AX phosphorylation) FANCB, Humans, Oncology & Carcinogenesis, Molecular Biology, Gene, Topoisomerase, Pro-(BID, CASPASE3/7) and anti-apoptotic effectors (BCL2), DNA Breaks, Neurosciences, Ribosomal RNA, medicine.disease, Brain Disorders, Brain Cancer, 030104 developmental biology, Apoptotic Protease-Activating Factor 1, DNA Topoisomerases, Type II, Doxorubicin, biology.protein, Cancer research, Ribosomal proteins subunits: (RPS11, 16, and 18), CRISPR-Cas Systems, Glioblastoma, DNA Topoisomerases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f691a3b95363dc26f76ef46b3bc89afe
http://europepmc.org/articles/PMC7646677

المؤلفون: Daniel Menendez, Jay R Anand, Carri C Murphy, Whitney J Bell, Jiaqi Fu, Nadia Slepushkina, Eugen Buehler, Scott E Martin, Madhu Lal-Nag, John Nitiss, Michael A Resnick

مصطلحات موضوعية: Biomedical and clinical sciences, Oncology and carcinogenesis, 32 Biomedical and Clinical Sciences, 3211 Oncology and Carcinogenesis, Rare Diseases, Orphan Drug, Genetics, Cancer, Biotechnology, 2.1 Biological and endogenous factors, 2 Aetiology, 5 Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, DNA, DNA Damage, DNA Topoisomerases, Type II, Etoposide, Humans, Mutation, Poisons, RNA, Small Interfering, Topoisomerase II Inhibitors, Tumor Suppressor Protein p53, ICE assay, Top2 covalent complexes, siRNA screen

Relation: https://figshare.com/articles/journal_contribution/Etoposide-induced_DNA_damage_is_increased_in_p53_mutants_identification_of_ATR_and_other_genes_that_influence_effects_of_p53_mutations_on_Top2-induced_cytotoxicity/25829200

الاتاحة: https://doi.org/10.25417/uic.25829200.v1
https://figshare.com/articles/journal_contribution/Etoposide-induced_DNA_damage_is_increased_in_p53_mutants_identification_of_ATR_and_other_genes_that_influence_effects_of_p53_mutations_on_Top2-induced_cytotoxicity/25829200

المؤلفون: Sen, N, Leonard, J, Torres, R, Garcia-Luis, J, Palou-Marin, G, Aragon Alcaide, L

المساهمون: Wellcome Trust

المصدر: 147 ; 134

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Cell Biology, MITOTIC CHROMOSOME CONDENSATION, TOPOISOMERASE-II, SACCHAROMYCES-CEREVISIAE, DNA TOPOISOMERASES, IN-VITRO, COHESION, DECATENATION, TOPOLOGY, PROTEIN, MITOSIS, DNA replication, SCI, Top2 (Topoisomerase 2), catenation, chromosome segregation, cohesin, condensin, Adenosine Triphosphatases, Anaphase, Chromatids, Chromosomes, Fungal, Type II, DNA, DNA-Binding Proteins, G2 Phase Cell Cycle Checkpoints

Relation: Molecular Cell; http://hdl.handle.net/10044/1/40855; 100955/Z/13/Z

الاتاحة: http://hdl.handle.net/10044/1/40855
https://doi.org/10.1016/j.molcel.2016.09.007