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المؤلفون: Irina A. Kirpich, Banrida Wahlang, Nicholas C. Alexander, Xiaohong Li, Matthew C. Cave, Eric C. Rouchka
المصدر: Toxicology Reports, Vol 8, Iss, Pp 536-547 (2021)
Toxicology Reportsمصطلحات موضوعية: Tjp1, tight junction protein 1, Health, Toxicology and Mutagenesis, RER, respiratory exchange rate, ACHS, anniston community healthy survey, Camp, cathelicidin anti-microbial peptide, 010501 environmental sciences, Toxicology, 01 natural sciences, chemistry.chemical_compound, 0302 clinical medicine, HFD, high fat diet, Tnfa, tumor necrosis factor, HOMA, homeostasis model assessment, RA1190-1270, Cldn, claudin, Constitutive androstane receptor, Aroclor1260, PCBs, Pck1, phosphoenolpyruvate carboxykinase 1, Pregnane X receptor, Fatty liver, Cdh5, adhesion molecule VE-cadherin, Regular Article, PXR, pregnane-xenobiotic receptor, Muc, mucin, Gut-liver, Knockout mouse, CAR, constitutive androstane receptor, NASH, nonalcoholic steatohepatitis, AhR, arylhydrocarbon receptor, medicine.medical_specialty, Fasn, fatty acid synthase, Biology, digestive system, Ppara, peroxisome-proliferator activated receptor alpha, 03 medical and health sciences, PCBs, polychlorinated biphenyls, Tff3, trefoil factor 3, Internal medicine, NAFLD, OTU, operational taxonomic unit, medicine, WT, wildtype, Microbiome, IBD, inflammatory bowel diseases, Gene knockout, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, TASH, toxicant-associated steatohepatitis, Fgf15, fibroblast growth factor 15, medicine.disease, LEfSe, linear discriminant analysis effect size, digestive system diseases, Ocln, occludin, Endocrinology, TASH, chemistry, Toxicology. Poisons, NAFLD, nonalcoholic fatty liver disease, Reg3g, regenerating islet-derived protein 3-gamma, Steatohepatitis, human activities, LDA, linear discriminant analysis, 030217 neurology & neurosurgery, Toxicant
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المؤلفون: Eric Delpire, Salma Omer, Mustafa H. Kabeer, Rainelli Koumangoye
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 239-255 (2020)مصطلحات موضوعية: 0301 basic medicine, TNF-α, tumor necrosis factor-α, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, NKCC1, Mucus Secretion, Solute Carrier Family 12, Member 2, Large intestine, Intestinal Mucosa, Colectomy, Original Research, Mice, Knockout, Submucosal glands, Muc2, mucin 2, Chemistry, Enterobacteriaceae Infections, Gastroenterology, Colitis, 3. Good health, medicine.anatomical_structure, LB, Luria Broth, 030211 gastroenterology & hepatology, FITC, fluorescein isothiocyanate, Goblet Cells, IHC, immunohistochemistry, Colon, PBS, phosphate-buffered saline, Bacterial Infection, Goblet Cell, 03 medical and health sciences, medicine, Animals, Humans, Secretion, NKCC1, Na-K-2Cl cotransporter 1, lcsh:RC799-869, TFF3, Trefoil factor 3, Goblet cell, KO, knockout, Water transport, Hepatology, WT, wild-type, Molecular biology, Mucus, Small intestine, Epithelium, Disease Models, Animal, 030104 developmental biology, UEA-1, Ulex europaeus agglutinin I, Chronic Disease, Mutation, Citrobacter rodentium, lcsh:Diseases of the digestive system. Gastroenterology, AB/PAS, Alcian blue and periodic acid–Schiff, DAPI, 4′,6-diamidino-2-phenylindole
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المؤلفون: Al-Shaibi, AA, Abdel-Motal, UM, Hubrack, SZ, Bullock, AN, Al-Marri, AA, Agrebi, N, Al-Subaiey, AA, Ibrahim, NA, Charles, AK, Elawad, M, Uhlig, HH, Lo, B
المساهمون: group, COLORS in IBD-Qatar study
المصدر: Cellular and Molecular Gastroenterology and Hepatology
مصطلحات موضوعية: Male, digestive system, TFF3, trefoil factor 3, ER, endoplasmic reticulum, HEK293T, Human Embryonic Kidney 293T, Structure-Activity Relationship, Intestinal Metaplasia, Mucoproteins, BiP, Binding Immunoglobulin Protein, Animals, Humans, Genetic Predisposition to Disease, Amino Acid Sequence, Intestinal Mucosa, Original Research, Mice, Knockout, Oncogene Proteins, Whole Genome Sequencing, CLCA1, Chloride Channel Accessory 1, IBD, inflammatory bowel disease, AGR2, anterior gradient 2, MUC, mucin, Siblings, Mucins, Sequence Analysis, DNA, respiratory system, Endoplasmic Reticulum Stress, Inflammatory Bowel Diseases, WT, wild-type, TBS, Tris-buffered saline, Disease Models, Animal, Mucus, Phenotype, Gastric Mucosa, MUC2, ER Stress, Disease Susceptibility, Goblet Cells, Biomarkers, AGR2, HA, hemagglutinin
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المؤلفون: Amy C. Engevik
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 551-552 (2020)مصطلحات موضوعية: Organoid, Microfluidics, Bioinformatics, Irritable Bowel Syndrome, EdU, 5-Ethynyl-2′-deoxyuridine, Lab-On-A-Chip Devices, Intestinal Mucosa, Irritable bowel syndrome, Cells, Cultured, Solute Carrier Family 12, Member 1, Original Research, Chemistry, Organ Chip, Organ-on-a-Chip, Gastroenterology, respiratory system, cAMP, adenosine 3′,5′-cyclic monophosphate, NKCC1, Na-K-Cl cotransporter 1, Intestine, Organoids, Editorial, PDMS, polydimethylsiloxane, Goblet Cells, Colon, Primary Cell Culture, TW, Transwell, PBS, phosphate-buffered saline, Organ Chip, Dinoprostone, Goblet Cell, medicine, DPBS, Dulbecco’s phosphate-buffered saline, PGE2, prostaglandin E2, Humans, CFTR, cystic fibrosis transmembrane conductance regulator, lcsh:RC799-869, TFF3, Trefoil factor 3, Hepatology, Colon Chip, Colon-on-a-Chip, MUC, mucin, Inflammatory Bowel Disease, HBSS, Hank’s balanced salt solution, medicine.disease, Mucus, digestive system diseases, Microfluidic, lcsh:Diseases of the digestive system. Gastroenterology, BSA, bovine serum albumin, PFA, paraformaldehyde
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المؤلفون: Xiaodun, Li, Sam, Kleeman, Sally B, Coburn, Carlo, Fumagalli, Juliane, Perner, Sriganesh, Jammula, Ruth M, Pfeiffer, Linda, Orzolek, Haiping, Hao, Philip R, Taylor, Ahmad, Miremadi, Núria, Galeano-Dalmau, Pierre, Lao-Sirieix, Maria, Tennyson, Shona, MacRae, Michael B, Cook, Rebecca C, Fitzgerald
المصدر: Gastroenterology
مصطلحات موضوعية: Adult, Male, BNE, squamous epithelium from above the Barrett’s segment, Biopsy, NE, normal esophagus, Gene Expression, Sensitivity and Specificity, TFF3, trefoil factor 3, Article, Epigenesis, Genetic, Barrett Esophagus, AUC, area under the curve, Esophagus, Diagnosis, BE, Barrett’s esophagus, miRNA, microRNA, Humans, Gene Regulation, Esophageal Adenocarcinoma, FFPE, formalin-fixed, paraffin-embedded, Aged, Biomarker, NES, normal esophageal squamous, Middle Aged, mRNA, messenger RNA, CI, confidence interval, MicroRNAs, UTR, untranslated region, Logistic Models, Area Under Curve, Case-Control Studies, Multivariate Analysis, Female
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المؤلفون: David J. Thornton, Jean-Eric Ghia, Nihal Haq, Yikang Deng, Huaqing Wang, Waliul I. Khan, Sumaira Z. Hasnain, Richard K. Grencis, Anna Velcich
المصدر: Gastroenterology
مصطلحات موضوعية: Male, Time Factors, Mice, SCID, Mucin 2, Mucin 5AC, Trichuris muris, BrdU, bromodeoxyuridine, Basic—Alimentary Tract, Mice, Adenosine Triphosphate, 0302 clinical medicine, Intestinal Diseases, Parasitic, Mice, Knockout, Mice, Inbred BALB C, 0303 health sciences, Host Resistance, biology, Gastroenterology, respiratory system, Innate Immunity, 3. Good health, Trichuris, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Goblet Cells, mMuc2, murine Muc2, ATP, adenosine triphosphate, Trichuriasis, digestive system, Permeability, Microbiology, Goblet Cell, 03 medical and health sciences, Th2 Cells, Species Specificity, Tff3, trefoil factor 3, Enteric Infection, medicine, Animals, RT-PCR, reverse transcription–polymerase chain reaction, SCID, severe combined immunodeficient, Immunity, Mucosal, 030304 developmental biology, Mucin-2, Goblet cell, KO, knockout, Innate immune system, Hepatology, Mucin, Relm, resistin-like molecule, TH, T helper, medicine.disease, biology.organism_classification, WT, wild-type, Mucus, Immunity, Innate, Mice, Inbred C57BL, Disease Models, Animal, Nematode infection, Immunology, Muc2, IL-4, interleukin-4, PAS, periodic acid Schiff, Energy Metabolism