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المؤلفون: Grace L. Guo, Xiaoyun Chen, Zheng Dong, Bilon Khambu, Xiao Ming Yin, Shengmin Yan
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Gut Dysbiosis, OST-β, organic solute transporter subunit-β, SQSTM1, sequestosome-1, FGF15, CK19, cytokeratin 19, Gut flora, FEX, fexaramine, SHP, small heterodimer partner, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, AST, aspartate transaminase, MCA, muricholic acid, CYP8B1, cytochrome p450 family 8b1, BLU, Blu-9931, TCDCA, taurochenodeoxycholic acid, Original Research, FGFR4, fibroblast growth factor receptor 4, TBA, total bile acid, Liver injury, CA, cholic acid, biology, Bile acid, Gastroenterology, qRT-PCR, quantitative real-time polymerase chain reaction, Liver, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, NRF2, nuclear factor erythroid 2-related factor 2, BA, bile acid, 030211 gastroenterology & hepatology, TDCA, taurodeoxycholic acid, medicine.drug, medicine.medical_specialty, GM, gut microbiota, ALT, alanine transaminase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, IBABP, ileal bile acid-binding protein, OST-α, organic solute transporter subunit-α, Liver Injury, ASBT (SLC10A2), apical sodium–bile acid transporter, CDCA, chenodeoxycholic acid, Bile Acids and Salts, CYP7A1, cytochrome p450 7a1, 03 medical and health sciences, FXR, farnesoid X receptor, ATG, autophagy-related gene, TUDCA, tauroursodeoxycholic acid, Internal medicine, medicine, Autophagy, BAS, bile acid sequestrants, lcsh:RC799-869, Cholestyramine, ALP, alkaline phosphatase, FGF15, fibroblast growth factor 15, SE, standard error, Hepatology, Fibroblast growth factor receptor 4, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, PCoA, principal coordinates analysis, BSH, bile salt hydrolase, ABX, antibiotics, TLCA, taurolithocholic acid, TMCA, tauromuricholic acid, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease
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المؤلفون: Stan F.J. van de Graaf, Reinout L.P. Roscam Abbing, Joanne M. Donkers, Michel van Weeghel, Johannes H.M. Levels, Ronald P.J. Oude Elferink, Anita Boelen, Alfred H. Schinkel
المساهمون: Tytgat Institute for Liver and Intestinal Research, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases, Experimental Vascular Medicine, ACS - Diabetes & metabolism, Laboratory for Endocrinology, Graduate School
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 451-466 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 10(3), 451-466. Elsevier Inc.مصطلحات موضوعية: 0301 basic medicine, OATP, organic anion transporting polypeptide, NTCP, 0302 clinical medicine, HFD, high fat diet, Glucagon-Like Peptide 1, VLDL, very low-density lipoprotein, TCDCA, taurochenodeoxycholic acid, Original Research, 2. Zero hunger, OATP, Bile acid, biology, TG, triglyceride, Chemistry, Thyroid, Gastroenterology, ELISA, enzyme-linked immunosorbent assay, cAMP, adenosine 3′,5′-cyclic monophosphate, NTCP, sodium taurocholate co-transporting polypeptide, Glucagon-like peptide-1, G protein-coupled bile acid receptor, 3. Good health, Organic anion-transporting polypeptide, Postprandial, medicine.anatomical_structure, Myrcludex B, GTT, glucose tolerance test, 030211 gastroenterology & hepatology, Dio, deiodinase, medicine.medical_specialty, HDV, hepatitis delta virus, medicine.drug_class, digestive system, Bile Acids and Salts, 03 medical and health sciences, Lipopeptides, FXR, farnesoid X receptor, Hepatitis B, Chronic, Internal medicine, medicine, Humans, Secretion, Obesity, lcsh:RC799-869, PEPCK, Phosphoenolpyruvate carboxykinase, KO, knockout, Hepatology, ALP, alkaline phosphatase, WT, wild-type, BAT, brown adipose tissue, 030104 developmental biology, Endocrinology, HBV, hepatitis B virus, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, FCS, fetal calf serum, NAFLD, nonalcoholic fatty liver disease, TC, taurocholic acid, Hormone
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المؤلفون: Grzych, Guillaume, Chavez-Talavera, Oscar, Descat, Amandine, Thuillier, Dorothee, Verrijken, An, Kouach, Mostafa, Legry, Vanessa, Verkindt, Helene, Raverdy, Violeta, Legendre, Benjamin, Caiazzo, Robert, Van Gaal, Luc, Goossens, Jean-Francois, Paumelle, Rejane, Francque, Sven, Pattou, Francois, Haas, Joel T., Tailleux, Anne, Staels, Bart
المساهمون: Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Groupe de Recherche sur les formes Injectables et les Technologies Associées - ULR 7365 (GRITA), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Recherche translationnelle sur le diabète - U 1190 (RTD), University of Antwerp (UA), Antwerp University Hospital [Edegem] (UZA), ANR-16-RHUS-0006,PreciNASH,PreciNASH(2016), ANR-10-LABX-0046,EGID,EGID Diabetes Pole(2010), European Project: 694717,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ImmunoBile(2016), European Project: 32591,HEPADIP, European Project: 305707,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,RESOLVE(2013), Derudas, Marie-Hélène, PreciNASH - - PreciNASH2016 - ANR-16-RHUS-0006 - RHUS - VALID, EGID Diabetes Pole - - EGID2010 - ANR-10-LABX-0046 - LABX - VALID, Bile acid, immune-metabolism, lipid and glucose homeostasis - ImmunoBile - - H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) 2016-09-01 - 2021-08-31 - 694717 - VALID, Hepatic and adipose tissue and functions in the metabolic syndrome - HEPADIP - 32591 - OLD, A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities, hypertriglyceridemia and low HDL-cholesterol - RESOLVE - - EC:FP7:HEALTH2013-01-01 - 2017-12-31 - 305707 - VALID, Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires (RNMCD - U1011), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille
المصدر: JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)مصطلحات موضوعية: GHDCA, glycolithocholic acid, taurohyodeoxycholic acid, OGTT, oral glucose tolerance test, GUDCA, glycoursodeoxycholic acid, TCDCA, FXR, farnesoid-X-receptor, UDCA, ADA, American Diabetes Association, IR, insulin resistance, GCA, glycocholic acid, THDCA, taurohyodeoxycholic acid, HCA, T2D, LCA, lithocholic acid, HCA, hyocholic acid, DCA, TCDCA, taurochenodeoxycholic acid, GCDCA, glycochenodeoxycholic acid, LCA, NASH, GCDCA, GHCA, glycohyocholic acid, TCA, cholic acid, [SDV] Life Sciences [q-bio], FPG, glycoursodeoxycholic acid, FXR, deoxycholic acid, glycocholic acid, non-alcoholic steatohepatitis, TDCA, taurodeoxycholic acid, HbA1c, NASH, non-alcoholic steatohepatitis, T2D, type 2 diabetes, Translational study, oral glucose tolerance test, digestive system, BA, UDCA, ursodeoxycholic acid, HDCA, glycochenodeoxycholic acid, TUDCA, tauroursodeoxycholic acid, NAFLD, OGTT, taurochenodeoxycholic acid, NAFL, non-alcoholic fatty liver, GCA, FPG, fasting plasma glycaemia, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, C4, bile acids, glycodeoxycholic acid, nutritional and metabolic diseases, HOMA2, homeostatic model assessment 2, hyocholic acid, digestive system diseases, farnesoid-X-receptor, DCA, deoxycholic acid, GUDCA, IR, TLCA, taurolithocholic acid, American Diabetes Association, CDCA, Human medicine, ABOS, Biological Atlas of Severe Obesity, HDCA, hyodeoxycholic acid, [SDV]Life Sciences [q-bio], HOMA2, taurodeoxycholic acid, taurolithocholic acid, C4, 7alpha-hydroxy-4-cholesten-3-one, insulin resistance, Biological Atlas of Severe Obesity, taurohyocholic acid, MAFLD, metabolic associated fatty liver disease, CA, cholic acid, CA, THCA, GHDCA, glycohyodeoxycholic acid, Diabetes, TLCA, glycohyocholic acid, ursodeoxycholic acid, TUDCA, TDCA, fasting plasma glycaemia, lithocholic acid, NAFL, BA, bile acids, chenodeoxycholic acid, non-alcoholic fatty liver, type 2 diabetes, ABOS, Research Article, NAFLD, non-alcoholic fatty liver disease, TCA, taurocholic acid, MAFLD, taurocholic acid, CDCA, chenodeoxycholic acid, metabolic associated fatty liver disease, glycated haemoglobin, homeostatic model assessment 2, Obesity, lcsh:RC799-869, tauroursodeoxycholic acid, 7alpha-hydroxy-4-cholesten-3-one, non-alcoholic fatty liver disease, THDCA, hyodeoxycholic acid, ADA, GDCA, lcsh:Diseases of the digestive system. Gastroenterology, HbA1c, glycated haemoglobin, GHCA, glycohyodeoxycholic acid, THCA, taurohyocholic acid, GLCA
وصف الملف: application/pdf
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المؤلفون: Hsiao D. Lieu, Gideon M. Hirschfield, Arun J. Sanyal, Stephen A. Harrison, Lei Ling, Ulrich Beuers, Alex M. DePaoli
المساهمون: Gastroenterology and Hepatology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevierمصطلحات موضوعية: Fibroblast growth factor, RC799-869, AST, aspartate aminotransferase, chemistry.chemical_compound, Chenodeoxycholic acid, GCA, glycocholic acid, Immunology and Allergy, Bile acid synthesis, LCA, lithocholic acid, NASH CRN, NASH Clinical Research Network, Non-alcoholic steatohepatitis, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, GCDCA, glycochenodeoxycholic acid, Bile acid, Primary sclerosing cholangitis, Deoxycholic acid, Gastroenterology, ELF test, Enhanced Liver Fibrosis test, Diseases of the digestive system. Gastroenterology, Ursodeoxycholic acid, FGF19, fibroblast growth factor 19, Glycodeoxycholic acid, G/T ratio, ratio of glycine to taurine conjugates of bile acids, NAS, non-alcoholic fatty liver disease activity score, BAAT, bile acid-CoA:amino acid N-acyltransferase, TDCA, taurodeoxycholic acid, medicine.drug, Research Article, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TCA, taurocholic acid, Glycocholic acid, digestive system, Pro-C3, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, Internal medicine, ALT, alanine aminotransferase, Internal Medicine, medicine, MRI-PDFF, magnetic resonance imaging-proton density fat fraction, GDCA, glycodeoxycholic acid, GLCA, glycolithocholic acid, Hepatology, ALP, alkaline phosphatase, Cholic acid, FGF19, Fibrogenesis, Endocrinology, PSC, primary sclerosing cholangitis, chemistry, DCA, deoxycholic acid, Pro-C3, neoepitope-specific N-terminal pro-peptide of type III collagen, TLCA, taurolithocholic acid
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المؤلفون: Song-Yang Zhang, Yu-Mi Lim, Tony K.T. Lam, Zahra Danaei, T.M. Zaved Waise
المصدر: Molecular Metabolism, Vol 44, Iss, Pp 101132-(2021)
Molecular Metabolismمصطلحات موضوعية: Male, 0301 basic medicine, USI, Upper small intestine, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Intestine, Small, Homeostasis, Glucose homeostasis, TCDCA, taurochenodeoxycholic acid, Nutrient sensing, digestive, oral, and skin physiology, Glucose tolerance, medicine.anatomical_structure, FXR, Original Article, Agonist, lcsh:Internal medicine, medicine.medical_specialty, medicine.drug_class, Taurochenodeoxycholic acid, 030209 endocrinology & metabolism, Ileum, digestive system, Bile Acids and Salts, Taurochenodeoxycholic Acid, 03 medical and health sciences, FXR, farnesoid X receptor, HF, high-fat, Internal medicine, medicine, Animals, lcsh:RC31-1245, Molecular Biology, Nutrients, Small intestine, Cell Biology, Glucose Tolerance Test, Bile acids, L. gasseri, Lactobacillus gasseri, Gastrointestinal Microbiome, Rats, Transplantation, Glucose, 030104 developmental biology, Endocrinology, chemistry, Farnesoid X receptor
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المؤلفون: Lutz Schmitt, Sander H. J. Smits, Tim Kroll
المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100087-(2021)
Journal of Lipid Researchمصطلحات موضوعية: 0301 basic medicine, G/T/DCA, glyco-/tauro-/deoxycholic acid, NBD, nucleotide binding domain, critical micelle concentration, TMD, transmembrane domain, 030204 cardiovascular system & hematology, MDR3, multidrug-resistant protein 3, ATPase activity, Biochemistry, PC, phosphatidylcholine, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Chenodeoxycholic acid, ABC, ATP binding cassette, LCA, lithocholic acid, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, CHAPSO, 3-[(3-cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate, Bile acid, TLCA, Deoxycholic acid, ABC transporter, Taurolithocholic acid, Research Article, medicine.drug_class, TCA, taurocholic acid, Taurochenodeoxycholic acid, QD415-436, CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, digestive system, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, DOPC, 1,2-dioleoyl-sn-glycero-3- phosphocholine, Bile Acids and Salts, 03 medical and health sciences, medicine, Nor-UDCA, BAM, bile acid mixture, G/T/UDCA, glyco/-tauro-/ursodeoxycholic acid, BSEP, bile salt export pump, bile acids, G/T/CA, glyco-/tauro-/cholic acid, Cholic acid, cholesterol, Cell Biology, Taurocholic acid, Bile Salt Export Pump, NTCP, sodium taurocholate transporting peptide, G/T/CDCA, glyco-/tauro-/chenodeoxycholic acid, 030104 developmental biology, DCA, deoxycholic acid, chemistry, TLCA, taurolithocholic acid, ABCB4/MDR3
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المؤلفون: Sven-Bastiaan Haange, Alesia Walker, Xin He, Ilias Lagkouvardos, Philippe Schmitt-Kopplin, Thomas Clavel, Yuwen Liu, Xinxin Ke, Martin von Bergen, Peter C.K. Cheung, Nico Jehmlich
المصدر: Molecular metabolism 22, 96-109 (2019). doi:10.1016/j.molmet.2019.01.012
Molecular Metabolism
Molecular Metabolism, Vol 22, Iss, Pp 96-109 (2019)
Mol. Metab. 22, 96-109 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Synbiotics, medicine.medical_treatment, Mice, Obese, Gut flora, TNF-α, tumor necrosis factor-α, law.invention, DCA, Deoxycholic acid, ωMCA, ω-Muricholic acid, Probiotic, Mice, 0302 clinical medicine, αMCA, α-Muricholic acid, law, TCA, Taurocholic acid, Food science, biology, TUDCA, Tauroursodeoxycholic acid, food and beverages, UDCA, Ursodeoxycholic acid, LBP, lipopolysaccharide-binding protein, Bifidobacterium animalis, ddc, LCA, Lithocholic acid, High-fat diet, MCP-1, monocyte chemotactic protein 1, Original Article, lcsh:Internal medicine, Lactobacillus paracasei, Normal diet, Dietary Intervention, Gut Microbiota, High-fat Diet, Obesity, 030209 endocrinology & metabolism, Gut microbiota, TCDCA, Taurochenodeoxycholic acid, Diet, High-Fat, SCFAs, short-chain fatty acids, THDCA, Taurohyodeoxycholic acid, 03 medical and health sciences, 7-oxoDCA, 7-oxodeoxycholic acid, medicine, βTMCA, β-Tauromuricholic acid, Animals, MDCA, Murideoxycholic acid, lcsh:RC31-1245, Molecular Biology, CA-7S, Cholic acid 7-sulfate, ωTMCA, ω-Tauromuricholic acid, Prebiotic, BAs, bile acids, αTMCA, α-Tauromuricholic acid, βMCA, β-Muricholic acid, Cell Biology, eAT, epididymal adipose tissue, biology.organism_classification, HDCA, Hyodeoxycholic acid, Gastrointestinal Microbiome, Mice, Inbred C57BL, Dietary intervention, 030104 developmental biology, CA, Cholic acid, alloCA, Allocholic acid, 3-dehydroCDCA, 3-dehydrochenodeoxycholic acid, Diet-induced obese, TDCA, Taurodeoxycholic acid
وصف الملف: application/pdf
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المؤلفون: Ronald P.J. Oude Elferink, D. Rudi de Waart, Sandra M. W. van de Wiel, Stan F.J. van de Graaf
المساهمون: Gastroenterology and Hepatology, Graduate School, AGEM - Endocrinology, metabolism and nutrition, Tytgat Institute for Liver and Intestinal Research, AGEM - Digestive immunity, ACS - Atherosclerosis & ischemic syndromes
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 5(3), 223-237. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 223-237 (2018)مصطلحات موضوعية: 0301 basic medicine, MDCKII, Madin–Darby canine kidney epithelial cells, medicine.drug_class, 03 medical and health sciences, Bile Acids, FXR, farnesoid X receptor, FACS, fluorescence-activated cell sorting, medicine, nucleoBAS, nucleus-localized bile acid sensor, lcsh:RC799-869, FRET, fluorescent resonance energy transfer, TCDCA, taurochenodeoxycholic acid, Epithelial polarity, Original Research, U2OS, human bone osteosarcoma epithelial cells, Hepatology, Bile acid, OSTα-OSTβ, organic solute transporter α-β, Chemistry, TICE, transintestinal cholesterol excretion, Gastroenterology, Transporter, FGF15/19, fibroblast growth factor 15/19, FDA, Food and Drug Administration, mRNA, messenger RNA, 3. Good health, Cell biology, 030104 developmental biology, Nuclear receptor, Biochemistry, FXR, FGF15/19, OSTα-OSTβ, Paracellular transport, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, Efflux, ASBT, apical sodium-dependent bile acid transporter, Fluorescence Resonance Energy Transfer (FRET), BAS, bile acid sensor
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المؤلفون: Anna, Baghdasaryan, Peter, Chiba, Michael, Trauner
المصدر: Molecular Aspects of Medicine
مصطلحات موضوعية: PGC-1α, peroxisome proliferator-activated receptor gamma coactivator-1 alpha, FXR, farnesoid X receptor (NR1H4), HNF4α, hepatocyte nuclear factor 4 alpha, CARM1, co-activator-associated arginine methyltransferase 1, OATP, organic anion transporting polypeptide, VDR (NR1I1), vitamin D receptor, Review, BCRP (ABCG2), breast cancer resistance protein, NDRG2, NMYC downstrean-regulated gene 2, MRP4 (ABCC4), multidrug resistance-associated protein 4, SRC2, steroid receptor co-activator 2, GGT, gamma-glutamyl transpeptidase, MDR1 (ABCB1), multidrug resistance protein 1, Nuclear receptors, GRE, glucocorticoid response element, CtBP, C-terminal binding protein, GCA, glycocholic acid, TβMCA, β-tauromuricholic acid, TNF-α, tumor necrosis factor alpha, ATB-binding cassette transporters, FGF19/FGF15, fibroblast growth factor 19/15, MARE, MAF recognition element, ATP Binding Cassette Transporter, Subfamily B, Member 11, TCDCA, taurochenodeoxycholic acid, CA, cholic acid, Cholestasis, ASBT (SLC10A2), apical sodium-dependent bile acid transporter, Symporters, AE2 (SLC4A2), anion exchanger 2, ABC, ATP-binding cassette, FXRE, FXR response element, cAMP, cyclic adenosine monophosphate, DILI, drug-induced liver injury, IL-6, interleukin 6, PL, phospholipid, TGR5, G protein coupled bile acid receptor, OCA, obeticholic acid, OSTα/OSTβ (SLC51A/SLC51B), organic solute transporter alpha/beta, LRH1 (NR5A2), liver receptor homologue 1, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, LPS, lipopolysaccharide, BRIC2, benign recurrent intrahepatic cholestasis type 2, LXR (NR1H3), liver X receptor, Transcriptional Activation, PFIC2, progressive familial intrahepatic cholestasis type 2, PXR (NR1I2), pregnane X receptor, TCA, taurocholic acid, RXRα (NR2B1), retinoid X receptor, Organic Anion Transporters, Sodium-Dependent, CCl4, carbone tetrachloride, UDCA, ursodeoxycholic acid, Bile Acids and Salts, CDCA, chenodeoxycholic acid, STAT-5, signal transducer and activator of transcription 5, LCA, litocholic acid, ALT, alanine aminotransferase, CBDL, common bile duct ligation, IR-1, inverse repeat 1, TUDCA, tauroursodeoxycholic acid, Humans, ICP, intrahepatic cholestasis of pregnancy, GR (NR3C1), glucocorticoid receptor, MRP2 (ABCC2), multidrug resistance-associated protein 2, TαMCA, α-tauromuricholic acid, TPN, total parenteral nutrition, ALP, alkaline phosphatase, IL-1β, interleukin-1 beta, SREBP1, sterol regulatory element-binding protein 1, Membrane Transport Proteins, Biological Transport, BSEP (ABCB11), bile salt export pump, MAF, musculo-aponeurotic fibrosacroma, ASCOM, activating signal cointegrator-2-containing complex, HNF1α, hepatocyte nuclear factor 1 alpha, MCL-1, myeloid cell leukemia factor 1, NTCP (SLC10A1), Na+-taurocholate cotransporting polypeptide solute carrier family 10 member 1, VPAC-1, vasoactive intestinal polypeptide activated receptor, AMPK, AMP-activated protein kinase, MRP3 (ABCC3), multidrug resistance-associated protein 3, NF-κB, nuclear factor kappa-B, PSC, primary sclerosing cholangitis, Gene Expression Regulation, DCA, deoxycholic acid, BS, bile salt, MDR2 (ABCB4), multidrug resistance protein 2, PPARα (NR1C1), peroxisome proliferator-activated receptor alpha, SHP (NR0B2), short heterodimer partner, RARα (NR1B1), retinoic acid receptor, ATP-Binding Cassette Transporters, PBC, primary biliary cirrhosis, PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma