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المؤلفون: Clare M. Lloyd, Simone A. Walker, Robert A. Oliver, James Cook, Anne O'Garra, Nicoletta Bruno, Sejal Saglani, Helen Stölting, William J. Branchett, Matthias Mack
المساهمون: Wellcome Trust
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: 0301 basic medicine, Chemokine, Allergy, αCCR2, Anti-CCR2, CCR8, cDC, Conventional dendritic cell, Chemokine receptor, 0302 clinical medicine, Immunology and Allergy, Medicine, Lung, Mice, Knockout, education.field_of_study, biology, T2, Type 2, Pyroglyphidae, P, Postnatal day, Innate lymphoid cell, AAD, Allergic airway disease, 1107 Immunology, monocyte, Chemokines, ILC2, Group 2 innate lymphoid cell, Mechanisms of Allergy/Immunology, TGF-β, BAL, Bronchoalveolar lavage, Immunology, Population, macrophage, MP, Mononuclear phagocyte, CCL8, Transforming Growth Factor beta1, 03 medical and health sciences, Immune system, Immunity, AM, Airway macrophage, Macrophages, Alveolar, Hypersensitivity, Animals, HDM, House dust mite, education, lung immunity, αCCR8, Anti-CCR8, business.industry, chemokine, mLN, Mediastinal lymph node, type 2 immunity, Allergens, Asthma, Mice, Inbred C57BL, 030104 developmental biology, IM, Interstitial macrophage, biology.protein, neonate, business, 030215 immunology
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2
المؤلفون: Hiroki Kimura, Fernando D. Martinez, Dean Billheimer, Dave Francisco, M. Conway, Donata Vercelli, Monica Kraft, Francesca Polverino
المصدر: Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunologyمصطلحات موضوعية: 0301 basic medicine, Hypersensitivity, Immediate, Male, Allergy, ACE2, urologic and male genital diseases, Atopy, provocative concentration of methacholine that resulted in a 20% fall in the FEV1, POSTN, 0302 clinical medicine, severe acute respiratory distress syndrome coronavirus 2, SERPINB2, CLCA1, calcium-activated chloride channel regulator 1, Medicine, Immunology and Allergy, transmembrane protease, serine 2, T2, type 2, Child, COVID-19, coronavirus disease 2019, Interleukin-13, Serine Endopeptidases, ALI, air-liquid interface, MERS-CoV, Middle East respiratory syndrome coronavirus, IL-13, Interleukin 13, Female, Angiotensin-Converting Enzyme 2, medicine.symptom, Coronavirus Infections, hormones, hormone substitutes, and hormone antagonists, Adult, NAEPP EPR3, National Heart, Lung, Pneumonia, Viral, Immunology, Inflammation, Respiratory Mucosa, ARIA, Allergic Rhinitis and its Impact on Asthma, Periostin, Peptidyl-Dipeptidase A, ACE2, angiotensin-converting enzyme 2, Article, 03 medical and health sciences, Betacoronavirus, T2 inflammation, Humans, Pandemics, TMPRSS2, Asthma, business.industry, SARS-CoV-2, nasal epithelial cells, FEV1, forced expiratory volume in one second, COVID-19, asthma, medicine.disease, peptidylprolyl isomerase A, SARS-CoV-2, Angiotensin II, respiratory tract diseases, IL, interleukin, CI, confidence interval, 030104 developmental biology, 030228 respiratory system, FeNO, fractional exhaled nitric oxide, FVC, forced vital capacity, periostin, PPIA, airway epithelial cells, Airway, business, serpin family B member 2, TMPRSS2, and Blood Institute and the National Asthma Education and Prevention Program. Expert Panel Report 3, PC20
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المؤلفون: Joe G. Zein, Ronald Strauss, Amy H. Attaway, Bo Hu, Alex Milinovich, Nesreen Jawhari, Soulaima S. Chamat, Victor E. Ortega
المصدر: The Journal of Allergy and Clinical Immunology. in Practice
مصطلحات موضوعية: COVID-19, Coronavirus disease 2019, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, AEC, Absolute eosinophil count, Inhaled corticosteroids, CBC, Complete blood count, SARS-CoV-2, Chronic obstructive pulmonary disease, T2, Type 2, COVID-19, COPD, Chronic obstructive pulmonary disease, ACE2, Angiotensin converting enzyme 2, BMI, Body mass index, CCCRR, Cleveland Clinic COVID-19 Research Registry, Asthma, ICS, Inhaled corticosteroids, ICU, Intensive care unit, Pulmonary Disease, Chronic Obstructive, COVID-19 Testing, Adrenal Cortex Hormones, Eosinophilia, Severe acute respiratory syndrome coronavirus 2, Humans, Immunology and Allergy, Original Article, RCT, Randomized controlled trial
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المؤلفون: Raphaël Enaud, Patrick Berger, Laurence Delhaes, Louise-Eva Vandenborght, Pierre-Olivier Girodet, Charlotte Urien, Stéphanie Ferreira, Noémie Coron
المصدر: Europe PubMed Central
The Journal of Allergy and Clinical Immunologyمصطلحات موضوعية: 0301 basic medicine, Male, Endotype, Exacerbation, V3-V4, Variable 3-variable 4 of the 16S rRNA encoding gene, microbiome, Severity of Illness Index, 0302 clinical medicine, Immunology and Allergy, Type 2 asthma, IL, Interleukin, OTU, Operational taxonomic unit, DNA, Fungal, medicine.diagnostic_test, ICS, Inhaled corticosteroid, T2, Type 2, Microbiota, Indoor environment, Dust, Middle Aged, ERS, European Respiratory Society, LABA, Long acting beta2 agonist, STB, Stable state, Air Pollution, Indoor, Female, medicine.symptom, EDC, Electrostatic Dust Collector, Environmental Monitoring, Spirometry, severe asthma, VRC, Voriconazole, Adult, DNA, Bacterial, BAL, Bronchoalveolar lavage, SA, Severe asthma, COBRA, Cohort of Bronchial obstruction and Asthma, Immunology, BMI, Body mass index, qPCR, Quantitative polymerase chain reaction, Article, EXA, Exacerbation of asthma, 03 medical and health sciences, mycobiome, medicine, ITS2, Internal transcribed spacer 2, Humans, Microbiome, FeNO, Asthma, Aged, business.industry, Sputum, medicine.disease, respiratory tract diseases, PERMANOVA, Permutational multivariate analysis of variance, 030104 developmental biology, 030228 respiratory system, NGS, Next generation sequencing, Metagenomics, PCoA, principal coordinates analysis, Exhaled nitric oxide, LAMA, Long acting muscarinic antagonist, OCS, Oral corticosteroid, business, FeNO, Fraction of exhaled nitric oxide, LDA, Linear discriminant analysis
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المؤلفون: Branchett, William J., Stölting, Helen, Oliver, Robert A., Walker, Simone A., Puttur, Franz, Gregory, Lisa G., Gabryšová, Leona, Wilson, Mark S., O'Garra, Anne, Lloyd, Clare M.
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: Severe asthma, BAL, Bronchoalveolar lavage, dendritic cell, AHR, Airway hyperresponsiveness, APC, Antigen-presenting cell, FoxP3, Forkhead box P3, macrophage, PAS, Periodic acid–Schiff, type 2–low asthma, Article, Teff, Effector T, Interferon-gamma, Mice, AM, Airway macrophage, Hypersensitivity, T1, Type 1, Animals, PMA, Phorbol 12-myristate 13-acetate, Myeloid Cells, HDM, House dust mite, IFN-γ, cRPMI, Complete RPMI, Mice, Knockout, moDC, Monocyte-derived dendritic cell, cDC2, Type 2 conventional dendritic cell, T2, Type 2, immune regulation, Pyroglyphidae, T cell, mLN, Mediastinal lymph node, T-Lymphocytes, Helper-Inducer, Allergens, Treg, Regulatory T, DC, Dendritic cell, IL-10Rα, IL-10 receptor α, Asthma, Interleukin-10, Mice, Inbred C57BL, Disease Models, Animal, AAD, Allergic airway disease, IMM, Inflammatory monocyte and macrophage, IL-10, IM, Interstitial macrophage, T17, Type 17, Ct, Threshold cycle, Female, Bronchial Hyperreactivity
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المؤلفون: Ghebre, Michael A., Pang, Pee Hwee, Diver, Sarah, Desai, Dhananjay, Bafadhel, Mona, Haldar, Koirobi, Kebadze, Tatiana, Cohen, Suzanne, Newbold, Paul, Rapley, Laura, Woods, Joanne, Rugman, Paul, Pavord, Ian D., Johnston, Sebastian L., Barer, Michael, May, Richard D., Brightling, Christopher E.
المصدر: Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunologyمصطلحات موضوعية: Adult, Male, factor and cluster analyses, Exacerbation, asthma and chronic obstructive pulmonary disease heterogeneity, VEGF, Vascular endothelial growth factor, Immunology, COPD, Chronic obstructive pulmonary disease, Article, chronic obstructive pulmonary disease, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, P/F ratio, Proteobacteria/Firmicutes ratio, medicine, T1, Type 1, Humans, Immunology and Allergy, inflammatory profiles, Prospective Studies, 030212 general & internal medicine, Microbiome, CCL13, microbiome abundances, Asthma, Inflammation, COPD, business.industry, T2, Type 2, Microbiota, Sputum, VAS, Visual analog scale, Eosinophil, medicine.disease, phylum and genus levels, TNF-R, TNF receptor, respiratory tract diseases, 3. Good health, medicine.anatomical_structure, 030228 respiratory system, Female, CCL26, medicine.symptom, business, IL-6R, IL-6 receptor