المؤلفون: Yazdi, Aliakbar Khalili, Perveen, Sumera, Dong, Cheng, Song, Xiaosheng, Dong, Aiping, Szewczyk, Magdalena M., Calabrese, Matthew F., Casimiro-Garcia, Agustin, Chakrapani, Subramanyam, Dowling, Matthew S., Ficici, Emel, Lee, Jisun, Montgomery, Justin I., O'Connell, Thomas N., Skrzypek, Grzegorz J., Tran, Tuan P., Troutman, Matthew D., Wang, Feng, Young, Jennifer A., Min, Jinrong, Barsyte-Lovejoy, Dalia, Brown, Peter J., Santhakumar, Vijayaratnam, Arrowsmith, Cheryl H., Vedadi, Masoud, Owen, Dafydd R.

المساهمون: Innovative Medicines Initiative

المصدر: RSC Medicinal Chemistry ; volume 15, issue 3, page 1066-1071 ; ISSN 2632-8682

الاتاحة: https://doi.org/10.1039/d3md00633f
http://pubs.rsc.org/en/content/articlepdf/2024/MD/D3MD00633F

المؤلفون: Righetto, Germanna Lima, Yin, Yanting, Duda, David M, Vu, Victoria, Szewczyk, Magdalena M, Zeng, Hong, Li, Yanjun, Loppnau, Peter, Mei, Tony, Li, Yen-Yen, Seitova, Alma, Patrick, Aaron N, Brazeau, Jean-Francois, Chaudhry, Charu, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Halabelian, Levon

المساهمون: Bahar, Ivet, Bayer AG, Boehringer Ingelheim, Bristol Myers Squibb, Genentech, Ontario Genomics Institute, Innovative Medicines Initiative, Janssen, Merck KGaA, Pfizer, Takeda

المصدر: PNAS Nexus ; volume 3, issue 4 ; ISSN 2752-6542

الاتاحة: http://dx.doi.org/10.1093/pnasnexus/pgae153
https://academic.oup.com/pnasnexus/advance-article-pdf/doi/10.1093/pnasnexus/pgae153/57194532/pgae153.pdf
https://academic.oup.com/pnasnexus/article-pdf/3/4/pgae153/57336401/pgae153.pdf

المؤلفون: Fnaiche, Ahmed, Chan, Hwai-Chien, Paquin, Alexis, Suárez, Narjara González, Vu, Victoria, Li, Fengling, Allali-Hassani, Abdellah, Ada Cao, Michelle, Szewczyk, Magdalena, M., Bolotokova, Albina, Allemand, Frédéric, Gelin, Muriel, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Vedadi, Masoud, Guichou, Jean-François, Annabi, Borhane, Gagnon, Alexandre

المساهمون: Université du Québec à Montréal = University of Québec in Montréal (UQAM), Structural Genomics Consortium, University of Toronto, Centre de Biologie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Department of Pharmacology and Toxicology Toronto, Ontario Institute for Cancer Research Canada (OICR), Ontario Institute for Cancer Research

المصدر: ISSN: 1948-5875 ; ACS Medicinal Chemistry Letters ; https://hal.science/hal-04707327 ; ACS Medicinal Chemistry Letters, 2023, 14 (12), pp.1746-1753. ⟨10.1021/acsmedchemlett.3c00386⟩.

مصطلحات موضوعية: YAP-TEAD, Hippo pathway, Transcription factors, Flufenamic acid, Covalent inhibitors, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

الاتاحة: https://hal.science/hal-04707327
https://hal.science/hal-04707327v1/document
https://hal.science/hal-04707327v1/file/ml3c00386_si_001.pdf
https://doi.org/10.1021/acsmedchemlett.3c00386

المؤلفون: Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud

المساهمون: National Institute of General Medical Sciences, Government of Ontario

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 7, page 5041-5060 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.2c02132
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c02132

المؤلفون: Hanley, Ronan P., Nie, David Y., Tabor, John R., Li, Fengling, Sobh, Amin, Xu, Chenxi, Barker, Natalie K., Dilworth, David, Hajian, Taraneh, Gibson, Elisa, Szewczyk, Magdalena M., Brown, Peter J., Barsyte-Lovejoy, Dalia, Herring, Laura E., Wang, Gang Greg, Licht, Jonathan D., Vedadi, Masoud, Arrowsmith, Cheryl H., James, Lindsey I.

المساهمون: National Science Foundation, Government of Canada, U.S. Department of Health and Human Services, American Cancer Society, Leukemia and Lymphoma Society, Princess Margaret Cancer Foundation, Structural Genomics Consortium

المصدر: Journal of the American Chemical Society ; volume 145, issue 14, page 8176-8188 ; ISSN 0002-7863 1520-5126

الاتاحة: https://doi.org/10.1021/jacs.3c01421
https://pubs.acs.org/doi/pdf/10.1021/jacs.3c01421

المؤلفون: Harding, Rachel J., Franzoni, Ivan, Mann, Mandeep K., Szewczyk, Magdalena M., Mirabi, Bijan, Ferreira de Freitas, Renato, Owens, Dominic D. G., Ackloo, Suzanne, Scheremetjew, Alexej, Juarez-Ornelas, Kevin A., Sanichar, Randy, Baker, Rachel J., Dank, Christian, Brown, Peter J., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Schapira, Matthieu, Lautens, Mark, Arrowsmith, Cheryl H.

المساهمون: Bayer, Merck KGaA, Genentech, Takeda Pharmaceutical Company, Austrian Science Fund, Pfizer, Bristol-Myers Squibb, Genome Canada, Natural Sciences and Engineering Research Council of Canada, Boehringer Ingelheim, Janssen Pharmaceuticals, Structural Genomics Consortium, EUbOPEN

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 15, page 10273-10288 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.3c00314
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00314

المؤلفون: Wu, Qin, Nie, David Y., Ba-alawi, Wail, Ji, YiShuai, Zhang, ZiWen, Cruickshank, Jennifer, Haight, Jillian, Ciamponi, Felipe E., Chen, Jocelyn, Duan, Shili, Shen, Yudao, Liu, Jing, Marhon, Sajid A., Mehdipour, Parinaz, Szewczyk, Magdalena M., Dogan-Artun, Nergiz, Chen, WenJun, Zhang, Lan Xin, Deblois, Genevieve, Prinos, Panagiotis, Massirer, Katlin B., Barsyte-Lovejoy, Dalia, Jin, Jian, De Carvalho, Daniel D., Haibe-Kains, Benjamin, Wang, XiaoJia, Cescon, David W., Lupien, Mathieu, Arrowsmith, Cheryl H.

المصدر: Nature Chemical Biology ; volume 18, issue 8, page 821-830 ; ISSN 1552-4450 1552-4469

الاتاحة: http://dx.doi.org/10.1038/s41589-022-01024-4
https://www.nature.com/articles/s41589-022-01024-4.pdf
https://www.nature.com/articles/s41589-022-01024-4

المؤلفون: Szewczyk, Magdalena M., Luciani, Genna M., Vu, Victoria, Murison, Alex, Dilworth, David, Barghout, Samir H., Lupien, Mathieu, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia

المساهمون: Pfizer, Natural Sciences and Engineering Research Council of Canada, Merck KGaA, Genentech, Ontario Genomics Institute, Wellcome Trust, Boehringer Ingelheim, European Commission, European Federation of Pharmaceutical Industries and Associations, Genome Canada, Innovative Medicines Initiative, Takeda Canada, Canadian Institutes of Health Research, Leukemia and Lymphoma Society of Canada, Janssen Pharmaceuticals

المصدر: Redox Biology ; volume 51, page 102282 ; ISSN 2213-2317

الاتاحة: http://dx.doi.org/10.1016/j.redox.2022.102282
https://api.elsevier.com/content/article/PII:S2213231722000544?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2213231722000544?httpAccept=text/plain

المؤلفون: Owens, Dominic D. G., Maitland, Matthew E. R., Khalili Yazdi, Aliakbar, Song, Xiaosheng, Reber, Viviane, Schwalm, Martin P., Machado, Raquel A. C., Bauer, Nicolas, Wang, Xu, Szewczyk, Magdalena M., Dong, Cheng, Dong, Aiping, Loppnau, Peter, Calabrese, Matthew F., Dowling, Matthew S., Lee, Jisun, Montgomery, Justin I., O’Connell, Thomas N., Subramanyam, Chakrapani, Wang, Feng, Adamson, Ella C., Schapira, Matthieu, Gstaiger, Matthias, Knapp, Stefan, Vedadi, Masoud, Min, Jinrong, Lajoie, Gilles A., Barsyte-Lovejoy, Dalia, Owen, Dafydd R., Schild-Poulter, Caroline, Arrowsmith, Cheryl H.

المساهمون: Gouvernement du Canada | Canadian Institutes of Health Research, Mitacs Elevate Postdoctoral Fellowship, Deutsche Forschungsgemeinschaft, EU/EFPIA/OICR/McGill/KTH/Diamond Innovative Medicines Initiative 2 Joint Undertaking, Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada, Cancer Research Society

المصدر: Nature Chemical Biology ; ISSN 1552-4450 1552-4469

الاتاحة: http://dx.doi.org/10.1038/s41589-024-01618-0
https://www.nature.com/articles/s41589-024-01618-0.pdf
https://www.nature.com/articles/s41589-024-01618-0

المؤلفون: Alqazzaz, Mona A., Luciani, Genna M., Vu, Victoria, Machado, Raquel A.C., Szewczyk, Magdalena M., Adamson, Ella C., Cheon, Sehyun, Li, Fengling, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia

المساهمون: Leukemia and Lymphoma Society of Canada

المصدر: Experimental Hematology ; volume 130, page 104135 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2023.11.009
https://api.elsevier.com/content/article/PII:S0301472X23017733?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X23017733?httpAccept=text/plain

المؤلفون: Igdoura, Suleiman A., Szewczyk, Magdalena M.

المصدر: Molecular Genetics and Metabolism ; volume 141, issue 2, page 107892 ; ISSN 1096-7192

الاتاحة: http://dx.doi.org/10.1016/j.ymgme.2023.107892
https://api.elsevier.com/content/article/PII:S109671922300522X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S109671922300522X?httpAccept=text/plain

المؤلفون: Harding, Rachel J, Deme, Justin C, Hevler, Johannes F, Tamara, Sem, Lemak, Alexander, Cantle, Jeffrey P, Szewczyk, Magdalena M, Begeja, Nola, Goss, Siobhan, Zuo, Xiaobing, Loppnau, Peter, Seitova, Alma, Hutchinson, Ashley, Fan, Lixin, Truant, Ray, Schapira, Matthieu, Carroll, Jeffrey B, Heck, Albert J R, Lea, Susan M, Arrowsmith, Cheryl H

المساهمون: Afd Biomol.Mass Spect. and Proteomics, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics

مصطلحات موضوعية: Cryoelectron Microscopy, Exons, Humans, Huntingtin Protein/genetics, Huntington Disease/genetics, Nuclear Proteins/genetics, Peptides/metabolism

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/415885

الاتاحة: https://dspace.library.uu.nl/handle/1874/415885

المؤلفون: Harding, Rachel J., Deme, Justin C., Hevler, Johannes F., Tamara, Sem, Lemak, Alexander, Cantle, Jeffrey P., Szewczyk, Magdalena M., Begeja, Nola, Goss, Siobhan, Zuo, Xiaobing, Loppnau, Peter, Seitova, Alma, Hutchinson, Ashley, Fan, Lixin, Truant, Ray, Schapira, Matthieu, Carroll, Jeffrey B., Heck, Albert J. R., Lea, Susan M., Arrowsmith, Cheryl H.

المساهمون: Huntington’s Disease Society of America, Huntington Society of Canada, CHDI Foundation

المصدر: Communications Biology ; volume 4, issue 1 ; ISSN 2399-3642

الاتاحة: http://dx.doi.org/10.1038/s42003-021-02895-4
https://www.nature.com/articles/s42003-021-02895-4.pdf
https://www.nature.com/articles/s42003-021-02895-4

المؤلفون: Szewczyk, Magdalena M., Owens, Dominic D. G., Barsyte-Lovejoy, Dalia

المصدر: Methods in Molecular Biology ; Chemogenomics ; page 137-148 ; ISSN 1064-3745 1940-6029 ; ISBN 9781071633960 9781071633977

الاتاحة: http://dx.doi.org/10.1007/978-1-0716-3397-7_10
https://link.springer.com/content/pdf/10.1007/978-1-0716-3397-7_10

المؤلفون: Szewczyk, Magdalena M., Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L., Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, dela Seña, Carlo C., Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Nara, Hiroshi, Baršytė-Lovejoy, Dalia

المصدر: Nature communications, London : Nature Research, 2020, vol. 11, iss. 1, p. 263-272 ; eISSN 2041-1723

وصف الملف: application/pdf

Relation: http://gtc.oai.elaba.lt/documents/68165796.pdf; http://gtc.lvb.lt/GTC:ELABAPDB68165796&prefLang=en_US

الاتاحة: http://gtc.oai.elaba.lt/documents/68165796.pdf
http://gtc.lvb.lt/GTC:ELABAPDB68165796&prefLang=en_US

المؤلفون: Szewczyk, Magdalena M., Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L., Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, dela Seña, Carlo C., Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Nara, Hiroshi, Barsyte-Lovejoy, Dalia

المصدر: Nature Communications ; volume 11, issue 1 ; ISSN 2041-1723

الاتاحة: https://doi.org/10.1038/s41467-020-16613-x
https://www.nature.com/articles/s41467-020-16613-x.pdf
https://www.nature.com/articles/s41467-020-16613-x

المؤلفون: Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Baršytė-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud

المصدر: Nature communications, London : Nature Research, 2019, vol. 10, iss. 1, p. 15933-15939 ; eISSN 2041-1723

مصطلحات موضوعية: PR Domain, Histone, Gene

وصف الملف: application/pdf

Relation: http://gtc.oai.elaba.lt/documents/54740056.pdf; http://gtc.lvb.lt/GTC:ELABAPDB54740056&prefLang=en_US

الاتاحة: http://gtc.oai.elaba.lt/documents/54740056.pdf
http://gtc.lvb.lt/GTC:ELABAPDB54740056&prefLang=en_US

المؤلفون: Fong, Jia Yi, Pignata, Luca, Goy, Pierre-Alexis, Kawabata, Kimihito Cojin, Lee, Stanley Chun-Wei, Koh, Cheryl M., Musiani, Daniele, Massignani, Enrico, Kotini, Andriana G., Penson, Alex, Wun, Cheng Mun, Shen, Yudao, Schwarz, Megan, Low, Diana HP., Rialdi, Alexander, Ki, Michelle, Wollmann, Heike, Mzoughi, Slim, Gay, Florence, Thompson, Christine, Hart, Timothy, Barbash, Olena, Luciani, Genna M., Szewczyk, Magdalena M., Wouters, Bas J., Delwel, Ruud, Papapetrou, Eirini P., Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Minden, Mark D., Jin, Jian, Melnick, Ari, Bonaldi, Tiziana, Abdel-Wahab, Omar, Guccione, Ernesto

المساهمون: NMRC, NRF, Cancer Science Institute of Singapore, NUS, Singapore Ministry of Education, Leukemia and Lymphoma Society, NIH, US Department of Defense Bone Marrow Failure Research Program, Edward P. Evans Foundation, Henry & Marilyn Taub Foundation, Pershing Square Sohn Foundation, Starr Foundation, Italian Ministry of Health, Epigen Flagship project, Italian Association for Cancer Research, H3 Biomedicine, Eli-Lilly and Prelude Therapeutics, Pfizer, Notable Labs, SGC, Leukemia Lymphoma Society of Canada, AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada, Innovative Medicines Initiative, Janssen, Merck, Novartis Pharma, Ontario Ministry of Economic Development and Innovation, São Paulo Research Foundation, Takeda, Wellcome Trust

المصدر: Cancer Cell ; volume 36, issue 2, page 194-209.e9 ; ISSN 1535-6108

الاتاحة: http://dx.doi.org/10.1016/j.ccell.2019.07.003
https://api.elsevier.com/content/article/PII:S1535610819303307?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1535610819303307?httpAccept=text/plain

المؤلفون: Luciani, Genna M., Xie, Lihua, Dilworth, David, Tierens, Anne, Moskovitz, Yoni, Murison, Alex, Szewczyk, Magdalena M., Mitchell, Amanda, Lupien, Mathieu, Shlush, Liran, Dick, John E., Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Minden, Mark D.

المساهمون: Leukemia Lymphoma Society of Canada

المصدر: Experimental Hematology ; volume 69, page 27-36 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2018.10.006
https://api.elsevier.com/content/article/PII:S0301472X18308683?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X18308683?httpAccept=text/plain

المؤلفون: White, Elizabeth J., Gyulay, Gabriel, Lhoták, Šárka, Szewczyk, Magdalena M., Chong, Taryne, Fuller, Mark T., Dadoo, Omid, Fox-Robichaud, Alison E., Austin, Richard C., Trigatti, Bernardo L., Igdoura, Suleiman A.

المساهمون: Heart and Stroke Foundation of Canada (HSF)

المصدر: Journal of Biological Chemistry ; volume 293, issue 38, page 14689-14706 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.ra118.004589
https://api.elsevier.com/content/article/PII:S0021925820308681?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820308681?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.RA118.004589