المؤلفون: Rajasekaran, Tamilselvan, Freestone, Graeme C, Galindo-Murillo, Rodrigo, Lugato, Barbara, Rico, Lorena, Salinas, Juan C, Gaus, Hans, Migawa, Michael T, Swayze, Eric E, Cheatham, Thomas E, Hanessian, Stephen, Seth, Punit P

المصدر: Journal of the American Chemical Society. 144(4)

مصطلحات موضوعية: Hydrocarbons, Kinetics, Molecular Dynamics Simulation, Nucleic Acid Conformation, Nucleic Acid Hybridization, Oligonucleotides, Organophosphonates, RNA, Chemical Sciences, General Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/78q1p72k

المؤلفون: Mummery, Catherine J., Börjesson-Hanson, Anne, Blackburn, Daniel J., Vijverberg, Everard G.B., De Deyn, Peter Paul, Ducharme, Simon, Jonsson, Michael, Schneider, Anja, Rinne, Juha O., Ludolph, Albert C., Bodenschatz, Ralf, Kordasiewicz, Holly, Swayze, Eric E., Fitzsimmons, Bethany, Mignon, Laurence, Moore, Katrina M., Yun, Chris, Baumann, Tiffany, Li, Dan, Norris, Daniel A., Crean, Rebecca, Graham, Danielle L., Huang, Ellen, Ratti, Elena, Bennett, C. Frank, Junge, Candice, Lane, Roger M.

المصدر: Mummery , C J , Börjesson-Hanson , A , Blackburn , D J , Vijverberg , E G B , De Deyn , P P , Ducharme , S , Jonsson , M , Schneider , A , Rinne , J O , Ludolph , A C , Bodenschatz , R , Kordasiewicz , H , Swayze , E E , Fitzsimmons , B , Mignon , L , Moore , K M , Yun , C , Baumann , T , Li , D , Norris , D A , Crean , R , Graham , D L ....

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/f597cd92-209a-4d6b-8aae-30edc7b5d6ef
https://research.rug.nl/en/publications/f597cd92-209a-4d6b-8aae-30edc7b5d6ef
https://doi.org/10.1038/s41591-023-02639-3
https://pure.rug.nl/ws/files/897396543/Author_Correction-_Tau-targeting_antisense_oligonucleotide_MAPTRx_in_mild_Alzheimer_s_disease-_a_phase_1b_randomized_placebo-controlled_trial.pdf
http://www.scopus.com/inward/record.url?scp=85174321210&partnerID=8YFLogxK

المؤلفون: Mummery, Catherine J., Börjesson-Hanson, Anne, Blackburn, Daniel J., Vijverberg, Everard G. B., de Deyn, Peter Paul, Ducharme, Simon, Jonsson, Michael, Schneider, Anja, Rinne, Juha O., Ludolph, Albert C., Bodenschatz, Ralf, Kordasiewicz, Holly, Swayze, Eric E., Fitzsimmons, Bethany, Mignon, Laurence, Moore, Katrina M., Yun, Chris, Baumann, Tiffany, Li, Dan, Norris, Daniel A., Crean, Rebecca, Graham, Danielle L., Huang, Ellen, Ratti, Elena, Bennett, C. Frank, Junge, Candice, Lane, Roger M.

المصدر: Mummery , C J , Börjesson-Hanson , A , Blackburn , D J , Vijverberg , E G B , de Deyn , P P , Ducharme , S , Jonsson , M , Schneider , A , Rinne , J O , Ludolph , A C , Bodenschatz , R , Kordasiewicz , H , Swayze , E E , Fitzsimmons , B , Mignon , L , Moore , K M , Yun , C , Baumann , T , Li , D , Norris , D A , Crean , R , Graham , D L ....

الاتاحة: https://research.vumc.nl/en/publications/c8a3aef5-a786-47fe-b672-ff5cd3b83eaf
https://doi.org/10.1038/s41591-023-02326-3
http://www.scopus.com/inward/record.url?scp=85153371450&partnerID=8YFLogxK

المؤلفون: Mummery, Catherine J, Borjesson-Hanson, Anne, Blackburn, Daniel J, Vijverberg, Everard GB, De Deyn, Peter Paul, Ducharme, Simon, Jonsson, Michael, Schneider, Anja, Rinne, Juha O, Ludolph, Albert C, Bodenschatz, Ralf, Kordasiewicz, Holly, Swayze, Eric E, Fitzsimmons, Bethany, Mignon, Laurence, Moore, Katrina M, Yun, Chris, Baumann, Tiffany, Li, Dan, Norris, Daniel A, Crean, Rebecca, Graham, Danielle L, Huang, Ellen, Ratti, Elena, Bennett, C Frank, Junge, Candice, Lane, Roger M

المصدر: Nature Medicine , 29 pp. 1437-1447. (2023)

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/10181642/1/Tau-targeting%20antisense%20oligonucleotide%20MAPTsubRxsub%20in%20mild%20Alzheimers%20disease%20a%20phase%201b,%20randomized,%20placebo-controlled%20t.pdf; https://discovery.ucl.ac.uk/id/eprint/10181642/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10181642/1/Tau-targeting%20antisense%20oligonucleotide%20MAPTsubRxsub%20in%20mild%20Alzheimers%20disease%20a%20phase%201b,%20randomized,%20placebo-controlled%20t.pdf
https://discovery.ucl.ac.uk/id/eprint/10181642/

المؤلفون: Qiao, Yuanyuan, Wotring, Jesse W., Zhang, Charles J., Jiang, Xia, Xiao, Lanbo, Watt, Andy, Gattis, Danielle, Scandalis, Eli, Freier, Susan, Zheng, Yang, Pretto, Carla D., Ellison, Stephanie J., Swayze, Eric E., Guo, Shuling, Sexton, Jonathan Z., Chinnaiyan, Arul M.

المساهمون: Roy, Arunava, National Institute of Diabetes and Digestive and Kidney Diseases, American Foundation for Pharmaceutical Education

المصدر: PLOS ONE ; volume 18, issue 2, page e0281281 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0281281
https://dx.plos.org/10.1371/journal.pone.0281281

المؤلفون: Vasquez, Guillermo, Migawa, Michael T., Wan, W. Brad, Low, Audrey, Tanowitz, Michael, Swayze, Eric E., Seth, Punit P.

المصدر: Nucleic Acid Therapeutics ; volume 32, issue 1, page 40-50 ; ISSN 2159-3337 2159-3345

الاتاحة: https://doi.org/10.1089/nat.2021.0064
https://www.liebertpub.com/doi/full-xml/10.1089/nat.2021.0064
https://www.liebertpub.com/doi/pdf/10.1089/nat.2021.0064

المؤلفون: Rahdar, Meghdad, McMahon, Moira A, Prakash, Thazha P, Swayze, Eric E, Bennett, C Frank, Cleveland, Don W

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 112(51)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Human Genome, Neurosciences, Base Sequence, Clustered Regularly Interspaced Short Palindromic Repeats, Genes, Synthetic, Genetic Engineering, Genome, Human, HEK293 Cells, Humans, Models, Genetic, Molecular Sequence Data, Nucleic Acid Conformation, RNA, RNA Editing, RNA, Guide, Kinetoplastida, genome editing, CRISPR/Cas9, synthetic crRNA, scrRNA

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/67b6k8q1

المؤلفون: Østergaard, Michael E, Dwight, Timothy, Berdeja, Andres, Swayze, Eric E, Jung, Michael E, Seth, Punit P

المصدر: The Journal of Organic Chemistry. 79(18)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Base Pairing, Carbohydrate Conformation, Carbohydrates, Molecular Conformation, Molecular Structure, Nucleic Acid Conformation, Nucleic Acids, RNA, Ribose, Organic Chemistry, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6sk623mh

المؤلفون: Jung, Michael E, Dwight, Timothy A, Vigant, Frederic, Østergaard, Michael E, Swayze, Eric E, Seth, Punit P

المصدر: Angewandte Chemie International Edition. 53(37)

مصطلحات موضوعية: Organic Chemistry, Chemical Sciences, Models, Molecular, Molecular Conformation, Molecular Structure, Nucleic Acid Conformation, Oligonucleotides, Thymidine, asymmetric synthesis, diastereoselectivity, duplex thermal stability, fluorination, modified nucleosides, Asymmetric synthesis, Diastereoselectivity, Duplex thermal stability, Fluorination, Modified nucleosides, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/40n36845

المؤلفون: Cole, Tracy A., Zhao, Hien, Collier, Timothy J., Sandoval, Ivette, Sortwell, Caryl E., Steece-Collier, Kathy, Daley, Brian F., Booms, Alix, Lipton, Jack, Welch, Mackenzie, Berman, Melissa, Jandreski, Luke, Graham, Danielle, Weihofen, Andreas, Celano, Stephanie, Schulz, Emily, Cole-Strauss, Allyson, Luna, Esteban, Quach, Duc, Mohan, Apoorva, Frank Bennett, C., Swayze, Eric E., Kordasiewicz, Holly B., Luk, Kelvin C., Paumier, Katrina L.

المصدر: Translational Neuroscience

Relation: https://scholar.barrowneuro.org/neurobiology/2040; https://doi.org/10.1172/jci.insight.135633

الاتاحة: https://scholar.barrowneuro.org/neurobiology/2040
https://doi.org/10.1172/jci.insight.135633

المؤلفون: Anderson, Brooke A, Freestone, Graeme C, Low, Audrey, De-Hoyos, Cheryl L, III, William J Drury, Østergaard, Michael E, Migawa, Michael T, Fazio, Michael, Wan, W Brad, Berdeja, Andres, Scandalis, Eli, Burel, Sebastien A, Vickers, Timothy A, Crooke, Stanley T, Swayze, Eric E, Liang, Xuehai, Seth, Punit P

المساهمون: Ionis Pharmaceuticals

المصدر: Nucleic Acids Research ; volume 49, issue 16, page 9026-9041 ; ISSN 0305-1048 1362-4962

الاتاحة: https://doi.org/10.1093/nar/gkab718
http://academic.oup.com/nar/article-pdf/49/16/9026/40358939/gkab718.pdf

المؤلفون: Vasquez, Guillermo, Freestone, Graeme C, Wan, W Brad, Low, Audrey, De Hoyos, Cheryl Li, Yu, Jinghua, Prakash, Thazha P, Ǿstergaard, Michael E, Liang, Xue-hai, Crooke, Stanley T, Swayze, Eric E, Migawa, Michael T, Seth, Punit P

المساهمون: Ionis Pharmaceuticals

المصدر: Nucleic Acids Research ; volume 49, issue 4, page 1828-1839 ; ISSN 0305-1048 1362-4962

الاتاحة: http://dx.doi.org/10.1093/nar/gkab047
http://academic.oup.com/nar/article-pdf/49/4/1828/36398933/gkab047.pdf

المؤلفون: Zhao, Hien Tran, John, Neena, Delic, Vedad, Ikeda-Lee, Karli, Kim, Aneeza, Weihofen, Andreas, Swayze, Eric E., Kordasiewicz, Holly B., West, Andrew B., Volpicelli-Daley, Laura A.

المصدر: Molecular Therapy - Nucleic Acids ; volume 24, page 1051-1053 ; ISSN 2162-2531

الاتاحة: https://doi.org/10.1016/j.omtn.2021.05.013
https://api.elsevier.com/content/article/PII:S2162253121001293?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2162253121001293?httpAccept=text/plain

المؤلفون: Prakash, Thazha P., Yu, Jinghua, Vasquez, Guillermo, Allerson, Charels R., Swayze, Eric E.

المصدر: Synlett; Apr2024, Vol. 35 Issue 6, p698-702, 5p

مصطلحات موضوعية: GUANOSINE, PHOSPHORAMIDITES, NUCLEIC acids, ADENOSINES, SMALL interfering RNA, NORMAL-phase chromatography, TETRAZOLES

المؤلفون: Sullivan, Jenna M., Mazur, Curt, Wolf, Daniel A., Horky, Laura, Currier, Nicolas, Fitzsimmons, Bethany, Hesterman, Jacob, Pauplis, Rachel, Haller, Scott, Powers, Berit, Tayefeh, Leighla, DeBrosse-Serra, Bea, Hoppin, Jack, Kordasiewicz, Holly, Swayze, Eric E., Verma, Ajay

المصدر: Journal of Translational Medicine ; volume 18, issue 1 ; ISSN 1479-5876

الاتاحة: http://dx.doi.org/10.1186/s12967-020-02461-2
https://link.springer.com/content/pdf/10.1186/s12967-020-02461-2.pdf
https://link.springer.com/article/10.1186/s12967-020-02461-2/fulltext.html

المؤلفون: Chappell, Alfred E, Gaus, Hans J, Berdeja, Andres, Gupta, Ruchi, Jo, Minji, Prakash, Thazha P, Oestergaard, Michael, Swayze, Eric E, Seth, Punit P

المساهمون: Ionis Pharmaceuticals, Inc.

المصدر: Nucleic Acids Research ; volume 48, issue 8, page 4382-4395 ; ISSN 0305-1048 1362-4962

الاتاحة: http://dx.doi.org/10.1093/nar/gkaa164
http://academic.oup.com/nar/article-pdf/48/8/4382/33150485/gkaa164.pdf

المؤلفون: Jafar-nejad, Paymaan, Powers, Berit, Soriano, Armand, Zhao, Hien, Norris, Daniel A, Matson, John, DeBrosse-Serra, Beatrice, Watson, Jamie, Narayanan, Padmakumar, Chun, Seung J, Mazur, Curt, Kordasiewicz, Holly, Swayze, Eric E, Rigo, Frank

المصدر: Nucleic Acids Research ; volume 49, issue 2, page 657-673 ; ISSN 0305-1048 1362-4962

الاتاحة: https://doi.org/10.1093/nar/gkaa1235
http://academic.oup.com/nar/article-pdf/49/2/657/36085025/gkaa1235.pdf

المؤلفون: Østergaard, Michael E, De Hoyos, Cheryl L, Wan, W Brad, Shen, Wen, Low, Audrey, Berdeja, Andres, Vasquez, Guillermo, Murray, Susan, Migawa, Michael T, Liang, Xue-hai, Swayze, Eric E, Crooke, Stanley T, Seth, Punit P

المساهمون: Ionis Pharmaceuticals

المصدر: Nucleic Acids Research ; volume 48, issue 4, page 1691-1700 ; ISSN 0305-1048 1362-4962

الاتاحة: http://dx.doi.org/10.1093/nar/gkaa031
http://academic.oup.com/nar/article-pdf/48/4/1691/32615556/gkaa031.pdf

المؤلفون: Watt, Andrew T., Swayze, Grant, Swayze, Eric E., Freier, Susan M.

المصدر: Nucleic Acid Therapeutics ; volume 30, issue 4, page 215-228 ; ISSN 2159-3337 2159-3345

الاتاحة: https://doi.org/10.1089/nat.2020.0847
https://www.liebertpub.com/doi/full-xml/10.1089/nat.2020.0847
https://www.liebertpub.com/doi/pdf/10.1089/nat.2020.0847

المؤلفون: Poplawski, Shane G., Garbett, Krassimira A., McMahan, Rebekah L., Kordasiewicz, Holly B., Zhao, Hien, Kennedy, Andrew J., Goleva, Slavina B., Sanders, Teresa H., Motley, S. Timothy, Swayze, Eric E., Ecker, David J., Sweatt, J. David, Michael, Todd P., Greer, Celeste B.

المساهمون: National Institute of Mental Health, Defense Advanced Research Projects Agency

المصدر: Molecular Therapy - Nucleic Acids ; volume 19, page 1399-1412 ; ISSN 2162-2531

الاتاحة: http://dx.doi.org/10.1016/j.omtn.2020.01.027
https://api.elsevier.com/content/article/PII:S2162253120300627?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2162253120300627?httpAccept=text/plain