المؤلفون: Thomsen, Majken, Jacobsen, Jan, Lillethorup, Thea Pinholt, Schacht, Anna C., Simonsen, Mette Irene Theilgaard, Romero-Ramos, Marina, Brooks, David J, Landau, Anne

المصدر: Thomsen , M , Jacobsen , J , Lillethorup , T P , Schacht , A C , Simonsen , M I T , Romero-Ramos , M , Brooks , D J & Landau , A 2021 , ' In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET ' , Journal of Cerebral Blood Flow and Metabolism , vol. 41 , no. 4 , pp. 819-830 . https://doi.org/10.1177/0271678X20931140

مصطلحات موضوعية: SV2A protein, [11C]UCB-J PET, neurodegeneration, rat, synapse

الاتاحة: https://pure.au.dk/portal/en/publications/f2447c14-1a4d-4049-9133-c6c6f735bdf6
https://doi.org/10.1177/0271678X20931140
http://www.scopus.com/inward/record.url?scp=85086463114&partnerID=8YFLogxK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7983510/pdf/10.1177_0271678X20931140.pdf

المؤلفون: Guillaume Becker, Sylvestre Dammicco, Mohamed Ali Bahri, Eric Salmon

المصدر: Molecules; Volume 25; Issue 10; Pages: 2303

مصطلحات موضوعية: SV2A protein, PET radiotracers, synaptic loss, radiochemistry, preclinical development, clinical outcomes

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/molecules25102303

الاتاحة: https://doi.org/10.3390/molecules25102303

المؤلفون: Chen, Zhao, Liao, Guang, Wang, Chunrong, Peng, Huirong, Shi, Yuting, Tang, Yongxiang, Li, Jian, Li, Yulai, Long, Tingting, Hou, Xuan, He, Lang, Qiu, Rong, Wan, Na, Chen, Dengming, Wang, Junling, Guo, Jifeng, Shen, Lu, Huang, Yiyun, Ashizawa, Tetsuo, Klockgether, Thomas, Tang, Beisha, Zhou, Ming, Hu, Shuo, He, Zhiyou, Jiang, Hong, Chen, Daji, Tang, Zhichao, Long, Zhe, Zou, Guangdong, Peng, Linliu, Wan, Linlin

المصدر: Movement disorders 38(6), 978-989 (2023). doi:10.1002/mds.29395

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Humans, Machado-Joseph Disease: diagnostic imaging, Pyrrolidines, Positron-Emission Tomography: methods, Ataxia, Membrane Glycoproteins: genetics, Nerve Tissue Proteins, SynVesT-1, PET, SCA3, SV2A, clinical biomarker, synaptic loss, SV2A protein, human, Membrane Glycoproteins

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:37023261; info:eu-repo/semantics/altIdentifier/issn/1531-8257; info:eu-repo/semantics/altIdentifier/issn/0885-3185; https://pub.dzne.de/record/257588; https://pub.dzne.de/search?p=id:%22DZNE-2023-00464%22

الاتاحة: https://pub.dzne.de/record/257588
https://pub.dzne.de/search?p=id:%22DZNE-2023-00464%22

المؤلفون: David J. Brooks, Anne M. Landau, Majken B. Thomsen, Anna C. Schacht, Thea P. Lillethorup, Jan Jacobsen, Mette Kildevæld Simonsen, Marina Romero-Ramos

المصدر: Thomsen, M, Jacobsen, J, Lillethorup, T P, Schacht, A C, Simonsen, M I T, Romero-Ramos, M, Brooks, D J & Landau, A 2021, ' In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET ', Journal of Cerebral Blood Flow and Metabolism, vol. 41, no. 4, pp. 819-830 . https://doi.org/10.1177/0271678X20931140
J Cereb Blood Flow Metab

مصطلحات موضوعية: Levetiracetam, Nerve Tissue Proteins, Pharmacology, Synaptic vesicle, Neuroprotection, Rats, Sprague-Dawley, Synapse, Lesion, Hydroxydopamines, 03 medical and health sciences, chemistry.chemical_compound, fluids and secretions, 0302 clinical medicine, synapse, In vivo, medicine, Animals, rat, Parkinson Disease, Secondary, 030304 developmental biology, SV2A, 0303 health sciences, Membrane Glycoproteins, Chemistry, Neurodegeneration, neurodegeneration, Original Articles, Quinolinic Acid, medicine.disease, Corpus Striatum, Rats, SV2A protein, Kinetics, Huntington Disease, Neuroprotective Agents, [11C]UCB-J PET, Neurology, Positron-Emission Tomography, Synapses, embryonic structures, Autoradiography, Anticonvulsants, Female, Neurology (clinical), Radiopharmaceuticals, medicine.symptom, Cardiology and Cardiovascular Medicine, 030217 neurology & neurosurgery, Quinolinic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d936e22954b72b8ef486a681c907b897
https://doi.org/10.1177/0271678x20931140

المؤلفون: Chittari Alekhya, Sravya Teddu, Dr. B.V. S. Lakshmi

المصدر: indo american joiurnal of pharmaceutical sciences, 03(09), 1068-1073, (2016-10-08)

مصطلحات موضوعية: SV2A protein than levetiracetam. Its effectiveness in reducing the frequency of seizures was demonstrated in 3 placebo-controlled trials in 1550 patients who were also taking other antiepileptic drugs (AEDs) concomitantly. In January 2016, the European Commission granted the marketing authorization for BRIVIACT

Relation: https://doi.org/; https://doi.org/10.5281/zenodo.159663; oai:zenodo.org:159663

الاتاحة: https://doi.org/10.5281/zenodo.159663

المؤلفون: Franklin I. Aigbirhio, Lei Li, Joseph J. Russell, Aniruddha Doke, Istvan Boros, Selena Milicevic Sephton, Tünde Miklovicz

المصدر: Journal of Labelled Compounds & Radiopharmaceuticals

مصطلحات موضوعية: Pyridines, chemistry.chemical_element, Chemistry Techniques, Synthetic, 01 natural sciences, Biochemistry, Synaptic vesicle, Suzuki cross‐coupling, 030218 nuclear medicine & medical imaging, Analytical Chemistry, Synthra RNPlus, Automation, 03 medical and health sciences, 0302 clinical medicine, carbon‐11 radiosynthesis, Drug Discovery, medicine, Animals, Radiology, Nuclear Medicine and imaging, Spectroscopy, SV2A, Radiochemistry, medicine.diagnostic_test, 010405 organic chemistry, Organic Chemistry, Synthon, Brain, Automated radiosynthesis, Protocols and Methods, [11C]UCB‐J, Macaca mulatta, synaptic density, Pyrrolidinones, SV2A protein, 0104 chemical sciences, chemistry, Positron emission tomography, Positron-Emission Tomography, Yield (chemistry), Synapses, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29967573be34017a7b046adcd8ff9b18
https://doi.org/10.1002/jlcr.3828

المؤلفون: Lee J., Daniels V., Sands Z.A., Lebon F., Shi J., Biggin P.C., Verma C.

المساهمون: BIOLOGY (NU)

المصدر: Unpaywall 20191101

مصطلحات موضوعية: carrier proteins and binding proteins, etiracetam, radioligand, SV2A protein, ucb 30889, unclassified drug, anticonvulsive agent, membrane protein, nerve protein, piracetam, protein binding, human, amino acid sequence, Article, binding site, controlled study, drug protein binding, drug structure, human cell, hydrophobicity, ligand binding, molecular dynamics, nonhuman, protein conformation, radioassay, sequence alignment, sequence analysis, site directed mutagenesis, structural homology, analogs and derivatives

Relation: Lee J., Daniels V., Sands Z.A., Lebon F., Shi J., Biggin P.C., Verma C. (2015). Exploring the interaction of SV2A with racetams using homology modelling, molecular dynamics and site-directed mutagenesis. PLoS ONE 10 (2) : e0116589. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0116589; https://scholarbank.nus.edu.sg/handle/10635/161744

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/161744

المؤلفون: Laurent Provins, Veronique Daniëls, Martyn Wood, Rafal M. Kaminski, Christian Wolff, Michel Gillard

المصدر: Journal of Pharmacology and Experimental Therapeutics. 372:1-10

مصطلحات موضوعية: Male, 0301 basic medicine, BRIVARACETAM, SV2A PROTEIN, Plasma protein binding, Brivaracetam, Rats, Sprague-Dawley, Mice, 0302 clinical medicine, BENZODIAZEPINES, Postsynaptic potential, Chlorocebus aethiops, Pharmacology & Pharmacy, Receptor, EPILEPSY, SV2A, Membrane Glycoproteins, LEVETIRACETAM, GABAA receptor, Chemistry, Imidazoles, HUMAN BRAIN, Pyrrolidinones, Receptor–ligand kinetics, BINDING-SITE, Biochemistry, COS Cells, Molecular Medicine, Anticonvulsants, Life Sciences & Biomedicine, Protein Binding, medicine.drug, EXPRESSION, Nerve Tissue Proteins, RAT-BRAIN, Synaptic vesicle, 03 medical and health sciences, Thiadiazoles, medicine, Animals, Humans, GABA Agonists, Pharmacology, Science & Technology, Receptors, GABA-A, Rats, Mice, Inbred C57BL, Kinetics, HEK293 Cells, 030104 developmental biology, LIGAND, 030217 neurology & neurosurgery

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbbdfc003be5b234997dc371aabea15
https://doi.org/10.1124/jpet.119.261149

المؤلفون: Becker, Guillaume, Dammicco, Sylvestre, Bahri, Mohamed Ali, SALMON, Eric

المصدر: Molecules, 25, 2303 (2020-05-14)

مصطلحات موضوعية: SV2A protein, PET radiotracers, synaptic los, radiochemistry, preclinical development, clinical outcomes, Human health sciences, Neurology, Sciences de la santé humaine, Neurologie

Relation: urn:issn:1420-3049

URL الوصول: https://orbi.uliege.be/handle/2268/256507

المؤلفون: Saak V. Ovsepian, K. Roger Aoki, Gary W. Lawrence, J. Oliver Dolly, Jiafu Wang

المصدر: Neuropharmacology 70, 287-295 (2013). doi:10.1016/j.neuropharm.2013.02.012

مصطلحات موضوعية: Botulinum Toxins, medicine.medical_treatment, Pharmacology, medicine.disease_cause, Synaptic Transmission, chemistry.chemical_compound, Botulinum Toxins, Type A, Cells, Cultured, drug effects [Synaptic Transmission], Membrane Glycoproteins, metabolism [Cholinergic Fibers], pharmacokinetics [Botulinum Toxins, Type A], Snap, Synaptic Potentials, Cholinergic Fibers, physiology [Cholinergic Fibers], Snap25 protein, rat, Acetylcholine, medicine.drug, Synaptosomal-Associated Protein 25, Nerve Tissue Proteins, Neurotransmission, Biology, Cleavage (embryo), pharmacokinetics [Botulinum Toxins], Cellular and Molecular Neuroscience, metabolism [Synaptosomal-Associated Protein 25], pharmacology [Botulinum Toxins], drug effects [Synaptic Potentials], medicine, Animals, ddc:610, DAPI, metabolism [Nerve Tissue Proteins], Protease, botulinum toxin type E, Dose-Response Relationship, Drug, Toxin, drug effects [Proteolysis], drug effects [Cholinergic Fibers], Molecular biology, Rats, Blockade, nervous system, chemistry, Proteolysis, Sv2a protein, rat, pharmacology [Botulinum Toxins, Type A], metabolism [Membrane Glycoproteins]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317a38f6ad08566639e25f14f4de7d13
https://doi.org/10.1016/j.neuropharm.2013.02.012

المؤلفون: Lawrence, Gary W, Ovsepian, Saak V, Wang, Jiafu, Aoki, K Roger, Dolly, J Oliver

المصدر: Neuropharmacology 70, 287-295 (2013). doi:10.1016/j.neuropharm.2013.02.012

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Animals, Botulinum Toxins: pharmacokinetics, Botulinum Toxins: pharmacology, Botulinum Toxins, Type A: pharmacokinetics, Type A: pharmacology, Cells, Cultured, Cholinergic Fibers: drug effects, Cholinergic Fibers: metabolism, Cholinergic Fibers: physiology, Dose-Response Relationship, Drug, Membrane Glycoproteins: metabolism, Nerve Tissue Proteins: metabolism, Proteolysis: drug effects, Rats, Synaptic Potentials: drug effects, Synaptic Transmission: drug effects, Synaptosomal-Associated Protein 25: metabolism, Membrane Glycoproteins, Nerve Tissue Proteins, Snap25 protein, rat, Sv2a protein, Synaptosomal-Associated Protein 25, Type A, botulinum toxin type E

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:23485402; info:eu-repo/semantics/altIdentifier/issn/1873-7064; info:eu-repo/semantics/altIdentifier/issn/0028-3908; https://pub.dzne.de/record/141273; https://pub.dzne.de/search?p=id:%22DZNE-2020-07595%22

الاتاحة: https://pub.dzne.de/record/141273
https://pub.dzne.de/search?p=id:%22DZNE-2020-07595%22

المؤلفون: Mattheisen, Manuel, Mühleisen, Thomas W, Witt, Stephanie H, Giegling, Ina, Sauer, Heinrich, Schulze, Thomas G, Rujescu, Dan, Nöthen, Markus M, Rietschel, Marcella, Cichon, Sven, Strohmaier, Jana, Treutlein, Jens, Nenadic, Igor, Alblas, Margrieta, Meier, Sandra, Degenhardt, Franziska, Herms, Stefan, Hoffmann, Per

المصدر: Schizophrenia research 141(2-3), 262-265 (2012). doi:10.1016/j.schres.2012.08.027

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Membrane Glycoproteins, Nerve Tissue Proteins, SV2A protein, human

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:23017826; info:eu-repo/semantics/altIdentifier/issn/0920-9964; info:eu-repo/semantics/altIdentifier/issn/1573-2509; https://pub.dzne.de/record/141673; https://pub.dzne.de/search?p=id:%22DZNE-2020-00004%22

الاتاحة: https://pub.dzne.de/record/141673
https://pub.dzne.de/search?p=id:%22DZNE-2020-00004%22

المؤلفون: Heinrich Sauer, Franziska Degenhardt, Stephanie H. Witt, Ina Giegling, Manuel Mattheisen, Thomas W. Mühleisen, Jens Treutlein, Sandra Meier, Sven Cichon, Stefan Herms, Jana Strohmaier, Marcella Rietschel, Markus M. Nöthen, Per Hoffmann, Dan Rujescu, Thomas G. Schulze, Margrieta A. Alblas, Igor Nenadic

المصدر: Schizophrenia research 141(2-3), 262-265 (2012). doi:10.1016/j.schres.2012.08.027

مصطلحات موضوعية: Adult, Male, Candidate gene, Genotype, Schizophrenia (object-oriented programming), Single-nucleotide polymorphism, Nerve Tissue Proteins, Biology, Polymorphism, Single Nucleotide, Linkage Disequilibrium, 03 medical and health sciences, 0302 clinical medicine, Gene Frequency, Germany, Genetic variation, Humans, SNP, Genetic Predisposition to Disease, ddc:610, International HapMap Project, Genetic Association Studies, Biological Psychiatry, 030304 developmental biology, SV2A, Genetics, 0303 health sciences, Membrane Glycoproteins, Haplotype, Middle Aged, SV2A protein, human, Psychiatry and Mental health, Schizophrenia, Female, 030217 neurology & neurosurgery, Follow-Up Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e6354170e47ce053e7a4e070e365f2
https://pub.dzne.de/record/141673

المؤلفون: Hildenbrand, Simone

المساهمون: Müller, Christa E., Bendas, Gerd

مصطلحات موضوعية: levetiracetam, brivaracetam, SV2A protein, radioligand binding studies, epilepsy, AMPA receptor, ddc:500, stat, envir

Relation: https://hdl.handle.net/20.500.11811/5419

الاتاحة: https://hdl.handle.net/20.500.11811/5419