المؤلفون: Alexander T. Young, Kien N. Ly, Callum Wilson, Klaus Lehnert, Russell G. Snell, Suzanne J. Reid, Jessie C. Jacobsen

المصدر: Disease Models & Mechanisms, Vol 11, Iss 11 (2018)

مصطلحات موضوعية: VMAT, Cat-1, Dopamine-serotonin transport disease, Caenorhabditis elegans, Animal model, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/11/11/dmm035709; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/fae458ff799740f39e42bfda3ada7ec0

المؤلفون: Kien Ly, Suzanne J. Reid, Russell G. Snell

المصدر: MethodsX, Vol 2, Iss C, Pp 59-63 (2015)

مصطلحات موضوعية: Rapid single worm RT-qPCR, Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2215016115000059; https://doaj.org/toc/2215-0161

URL الوصول: https://doaj.org/article/ebe05e2899d2407c8d3943e6e3301bf7

المؤلفون: Stefano Patassini, Paul Begley, Jingshu Xu, Stephanie J. Church, Nina Kureishy, Suzanne J. Reid, Henry J. Waldvogel, Richard L. M. Faull, Russell G. Snell, Richard D. Unwin, Garth J. S. Cooper

المصدر: Metabolites, Vol 9, Iss 6, p 113 (2019)

مصطلحات موضوعية: Huntington’s disease, neurodegeneration, vitamin B5, acetyl-coenzyme A, brain energy metabolism, acetylcholine biosynthesis, metabolomics, bioinformatics, data visualisation, data analytics, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-1989/9/6/113; https://doaj.org/toc/2218-1989

URL الوصول: https://doaj.org/article/14ecf4db38ce4f1f8867a6780060e37d

المؤلفون: Suzanne J. Reid, Mark I. Rees, Willeke M.C. van Roon-Mom, A.Lesley Jones, Marcy E. MacDonald, Greg Sutherland, Matthew J. During, Richard L.M. Faull, Michael J. Owen, Mike Dragunow, Russell G. Snell

المصدر: Neurobiology of Disease, Vol 13, Iss 1, Pp 37-45 (2003)

مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996103000147; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/1fcb9f531c064e41b56b2d9afc9efd38

المؤلفون: Andrew Jiang, Klaus Lehnert, Suzanne J. Reid, Renee R. Handley, Jessie C. Jacobsen, Syke R. Rudiger, Clive J. McLaughlan, Paul J. Verma, C. Simon Bawden, Russell G. Snell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1c9e89c452923eaa61b43761ee8c053c
https://doi.org/10.1101/2023.02.19.529150

المؤلفون: Henry J. Waldvogel, Richard L.M. Faull, Samantha J. Murray, Russell G. Snell, Brittney L. Black, Suzanne J. Reid, Skye R. Rudiger, C. Simon Bawden

المصدر: Journal of Chemical Neuroanatomy. 97:43-56

مصطلحات موضوعية: 0301 basic medicine, Sheep, Substantia nigra, Context (language use), Human brain, Biology, Substantia Nigra, 03 medical and health sciences, Cellular and Molecular Neuroscience, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Neurochemical, nervous system, Basal ganglia, medicine, Animals, Gross anatomy, Neurochemistry, Neuroscience, 030217 neurology & neurosurgery, Neuroanatomy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1995a77d41bf1d729436ed4e9fb4c11c
https://doi.org/10.1016/j.jchemneu.2019.01.007

المؤلفون: Richard L.M. Faull, John F. Pearson, James F. Gusella, Rudiger Brauning, Clive J. McLaughlan, Stefano Patassini, Skye R. Rudiger, Benjamin T Day, Paul S. MacLean, Richard D. Unwin, Garth J. S. Cooper, Emily R Mears, Paul J. Verma, Henry J. Waldvogel, Simon C Bawden, Suzanne J. Reid, Marcy E. MacDonald, Matthew J Grant, Renee R. Handley, Russell G. Snell

المصدر: Journal of Huntington's Disease

مصطلحات موضوعية: Proteomics, Research Report, sheep, Systems biology, Disease, Biology, computer.software_genre, Cellular and Molecular Neuroscience, Metabolomics, computational biology, Huntington's disease, medicine, Animals, Humans, genetics, database, Database, Mechanism (biology), Online database, Brain, systems biology, medicine.disease, Omics, metabolomics, animal models, Huntington Disease, Cohort, Neurology (clinical), RNA-seq, computer, Huntington’s disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e08657a0a43b835bb449c5a0dde17f5
https://pubmed.ncbi.nlm.nih.gov/34420978

المؤلفون: Michelle Glass, Ailsa L. McGregor, Suzanne J. Reid, Russell G. Snell, Mike Dragunow, Malvindar K. Singh-Bains, Pritika Narayan, Emma L. Scotter, Nasim F. Mehrabi, Richard L.M. Faull

المصدر: Neurobiology of Disease, Vol 146, Iss, Pp 105092-(2020)

مصطلحات موضوعية: 0301 basic medicine, Huntingtin, Nerve Tissue Proteins, Histone Deacetylases, lcsh:RC321-571, Histone H4, Animals, Genetically Modified, 03 medical and health sciences, 0302 clinical medicine, Huntington's disease, Mutant huntingtin aggregate, medicine, Animals, Humans, Epigenetics, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Sheep, biology, Brain, Epigenome, medicine.disease, Histone Deacetylase Inhibitors, Disease Models, Animal, 030104 developmental biology, Histone, Huntington Disease, Neurology, Histone acetylation, Cancer research, biology.protein, Transgenic HD sheep, Histone deacetylase, Trinucleotide repeat expansion, Acetyl histone H4, Protein Processing, Post-Translational, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cd463e151c45f35f1bccdfe9bc6495
https://pubmed.ncbi.nlm.nih.gov/32979507

المؤلفون: Jessie C. Jacobsen, C. Simon Bawden, Skye R. Rudiger, Clive J. Mclaughlan, Suzanne J. Reid, Henry J. Waldvogel, Marcy E. Macdonald, James F. Gusella, Simon K. Walker, Jennifer M. Kelly, Graham C. Webb, Richard L. M. Faull, Mark I. Rees, Russell G. Snell

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860888/pdf/ddq063.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.665.4500; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860888/pdf/ddq063.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.665.4500
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860888/pdf/ddq063.pdf

المؤلفون: Richard L.M. Faull, Liam Williams, Fiona C.A. Geraerts, Suzanne J. Reid, Jessie C. Jacobsen, Russell G. Snell

المصدر: Journal of Huntington's Disease. 5:297-301

مصطلحات موضوعية: 0301 basic medicine, Huntingtin, 030105 genetics & heredity, Biology, Gyrus Cinguli, Instability, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Gyrus, Huntington's disease, mental disorders, medicine, Huntingtin Protein, Humans, Allele, Analysis of Variance, Motor Cortex, medicine.disease, Huntington Disease, medicine.anatomical_structure, Neurology (clinical), Trinucleotide Repeat Expansion, Trinucleotide repeat expansion, Neuroscience, 030217 neurology & neurosurgery, Motor cortex

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44520ce8bcef71009ed7d3f5f2a9e9a8
https://doi.org/10.3233/jhd-160203

المؤلفون: Richard L.M. Faull, Garth J. S. Cooper, Mike Dragunow, Richard D. Unwin, Stephanie J. Church, Russell G. Snell, Suzanne J. Reid, Stefano Patassini, Maurice A. Curtis, Paul Begley, Henry J. Waldvogel, Eric H. Kim, Jingshu Xu

المصدر: Patassini, S, Begley, P, Xu, J, Church, S, Reid, S J, Kim, E H, Curtis, M A, Dragunow, M, Waldvogel, H J, Snell, R G, Unwin, R, Faull, R L M & Cooper, G 2016, ' Metabolite mapping reveals severe widespread perturbation of multiple metabolic processes in Huntington’s disease human brain ', Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1862, no. 9, pp. 1650-1662 . https://doi.org/10.1016/j.bbadis.2016.06.002

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Metabolite, Brain urea metabolism, Metabolic Brain Disease, Biology, Neurodegenerative disease, Gas Chromatography-Mass Spectrometry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Metabolomics, Huntington's disease, Internal medicine, medicine, Huntingtin Protein, Humans, Tissue Distribution, Molecular Biology, Aged, Genetics, Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, Metabolic brain disease, Neurodegeneration, Brain, Human brain, Polyglutamine tract, Middle Aged, medicine.disease, Inositol pathway, 3. Good health, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Huntington Disease, chemistry, Case-Control Studies, Polyol pathway, Metabolome, Molecular Medicine, Female, 030217 neurology & neurosurgery, Metabolic Networks and Pathways

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d790f5a42a73f87aa18b7a5c77f8f3

المؤلفون: Edith L. Pfister, Tim Kuchel, Lori A. Kennington, Florie Borel, Natalie DiNardo, Ellen Sapp, Faith Conroy, Marian DiFiglia, Xin Han, Gwladys Gernoux, A. Jennifer Morton, Miguel Sena-Esteves, Richard P. Moser, Neil Aronin, Danjing Hu, David Howland, Erica Mondo, Suzanne J. Reid, Guangping Gao, Emily S. Johnson, Christian Mueller, Pengpeng Liu, Cara K. Fraser, Petr Vodicka

المساهمون: Morton, Jennifer [0000-0003-0181-6346], Apollo - University of Cambridge Repository

مصطلحات موضوعية: 0301 basic medicine, congenital, hereditary, and neonatal diseases and abnormalities, Huntingtin, Transgene, Genetic Vectors, Striatum, Genome, Viral, Kidney, Injections, Animals, Genetically Modified, 03 medical and health sciences, Electrolytes, Huntington's disease, RNA interference, mental disorders, Genetics, Huntingtin Protein, medicine, Gene silencing, Animals, Humans, RNA, Messenger, Molecular Biology, Research Articles, Immunoassay, Neurons, Sheep, biology, AAV, Dependovirus, medicine.disease, Cell biology, nervous system diseases, Neostriatum, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Huntington Disease, nervous system, large animal models, Liver, RNAi, biology.protein, Molecular Medicine, Mutant Proteins, Microglia, NeuN

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0559c7eac6c260f5911cac3ddf9011

المؤلفون: Renee R, Handley, Suzanne J, Reid, Rudiger, Brauning, Paul, Maclean, Emily R, Mears, Imche, Fourie, Stefano, Patassini, Garth J S, Cooper, Skye R, Rudiger, Clive J, McLaughlan, Paul J, Verma, James F, Gusella, Marcy E, MacDonald, Henry J, Waldvogel, C Simon, Bawden, Richard L M, Faull, Russell G, Snell

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 114(52)

مصطلحات موضوعية: Adult, Male, Huntingtin Protein, Sheep, Corpus Striatum, Animals, Genetically Modified, Disease Models, Animal, Huntington Disease, PNAS Plus, Animals, Humans, Urea, Female, Trinucleotide Repeat Expansion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ca11c89799110a8c1298c3a591fb000c
https://pubmed.ncbi.nlm.nih.gov/29229845

المؤلفون: Alex Stortchevoi, Serkan Erdin, Colby Chiang, Carrie Hanscom, Jessie C. Jacobsen, Marcy E. MacDonald, Suzanne J. Reid, Carl Ernst, Russell G. Snell, James F. Gusella, Ian Blumenthal, Douglas Barker, Michael E. Talkowski, Renee R. Handley, A. Jennifer Morton

المساهمون: Morton, Jennifer [0000-0003-0181-6346], Apollo - University of Cambridge Repository

المصدر: Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Operations research, Transgene, Mice, Transgenic, Computational biology, Article, 03 medical and health sciences, Exon, Mice, Transcription (biology), Medicine, Animals, Humans, Gene, Sequence Deletion, Gene Rearrangement, Multidisciplinary, business.industry, Gene Expression Profiling, Gene rearrangement, Sequence Analysis, DNA, Phenotype, 3. Good health, Gene expression profiling, Transgenesis, Disease Models, Animal, 030104 developmental biology, Huntington Disease, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce295a3e3cdd0af1ffe28b61d11ded7
http://europepmc.org/articles/PMC5264158

المؤلفون: Russell G. Snell, A. Jennifer Morton, Clive J. McLaughlan, Suzanne J. Reid, Marcy E. MacDonald, Richard L.M. Faull, Stefano Patassini, Henry J. Waldvogel, Jessie C Jacobsen, Renee R. Handley, Andreas Weiss, Alexander P. Osmand, James F. Gusella, C. Simon Bawden, Skye R. Rudiger

المصدر: Journal of Huntington's Disease. 2:279-295

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Transgene, Intranuclear Inclusion Bodies, Nerve Tissue Proteins, Striatum, Biology, Animals, Genetically Modified, Cellular and Molecular Neuroscience, Huntington's disease, Cortex (anatomy), Piriform cortex, Neuropil, medicine, Huntingtin Protein, Animals, Humans, Sheep, Domestic, Cerebral Cortex, medicine.disease, Disease Models, Animal, Huntington Disease, Globus pallidus, medicine.anatomical_structure, nervous system, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa599777fb3a69f64f0d4fb4645e0f60
https://doi.org/10.3233/jhd-130067

المؤلفون: Carrie Hanscom, Cynthia C. Morton, Mark L. Borowsky, Charles Lee, Amelia M. Lindgren, Carl Ernst, Jessie C Jacobsen, Adrian Heilbut, Marcy E. MacDonald, Mark J. Daly, Michael E. Talkowski, C. Simon Bawden, Yiping Shen, Clive J. McLaughlan, Ian Blumenthal, Suzanne J. Reid, Richard L.M. Faull, Ryan E. Mills, Russell G. Snell, Toshiro K. Ohsumi, Colby Chiang, Ira M. Hall, Skye R. Rudiger, Andrew Kirby, James F. Gusella

المصدر: Nature genetics

مصطلحات موضوعية: DNA End-Joining Repair, Transgene, Molecular Sequence Data, Chromosomal translocation, Chromosomal rearrangement, Biology, Translocation, Genetic, Article, Germline, Animals, Genetically Modified, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Neoplasms, Genetics, Homologous chromosome, Animals, Humans, Germ-Line Mutation, Oligonucleotide Array Sequence Analysis, 030304 developmental biology, Gene Rearrangement, 0303 health sciences, Chromothripsis, Breakpoint, Chromosome Breakage, Sequence Analysis, DNA, chemistry, Chromosome Inversion, 030217 neurology & neurosurgery, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97f3e00497651d86b2a394692ab4de0
https://doi.org/10.1038/ng.2202

المؤلفون: Marcy E. MacDonald, Vladimir Obolonkin, Stefano Patassini, Henry J. Waldvogel, Russell G. Snell, Renee R. Handley, Richard L.M. Faull, Suzanne J. Reid, James F. Gusella, Jessie C. Jacobsen, Clive J. McLaughlan, C. Simon Bawden, Skye R. Rudiger

المصدر: Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Cerebellum, medicine.medical_specialty, Pathology, Huntingtin, Transgene, Hippocampus, Biology, Gas Chromatography-Mass Spectrometry, Article, Animals, Genetically Modified, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, Huntington's disease, Internal medicine, medicine, Metabolome, Animals, Humans, Amino Acids, Sheep, Domestic, Multidisciplinary, Fatty Acids, Motor Cortex, medicine.disease, Circadian Rhythm, Disease Models, Animal, Huntington Disease, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Liver, Organ Specificity, Asymptomatic Diseases, Female, Trinucleotide repeat expansion, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b887b8b89ebba8f9973b4b17930457
https://doi.org/10.1038/srep20681

المؤلفون: Richard L.M. Faull, Suzanne J. Reid, Garth J. S. Cooper, Maurice A. Curtis, Mike Dragunow, Stefano Patassini, Henry J. Waldvogel, Russell G. Snell, Paul Begley, Stephanie J. Church, Richard D. Unwin, Jingshu Xu

المصدر: Biochemical and biophysical research communications. 468(1-2)

مصطلحات موضوعية: Male, medicine.medical_specialty, Biophysics, Biology, Biochemistry, Gas Chromatography-Mass Spectrometry, Pathogenesis, Huntington's disease, Internal medicine, medicine, Huntingtin Protein, Humans, Urea, Molecular Biology, Aged, Neurodegeneration, Brain, Cell Biology, Human brain, Polyglutamine tract, Middle Aged, medicine.disease, Endocrinology, medicine.anatomical_structure, Huntington Disease, Urea cycle, Case-Control Studies, Forebrain, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae51aee37920c9d1d6502c6db0c592a
https://pubmed.ncbi.nlm.nih.gov/26522227

المؤلفون: Willeke M. C. van Roon-Mom, Richard L.M. Faull, Mike Dragunow, Russell G. Snell, Mark I. Rees, Michael John Owen, Suzanne J. Reid, Phil C. Wood

المصدر: Molecular Brain Research. 125:120-128

مصطلحات موضوعية: Male, Genotype, tau Proteins, Biology, Cellular and Molecular Neuroscience, Apolipoproteins E, Alzheimer Disease, medicine, Huntingtin Protein, Humans, Spinocerebellar Ataxias, Molecular Biology, Aged, Aged, 80 and over, Neurons, Genetics, Amyloid beta-Peptides, Neurodegeneration, Wild type, Brain, Neurofibrillary Tangles, Neurofibrillary tangle, Middle Aged, Polyglutamine tract, TATA-Box Binding Protein, medicine.disease, Cell biology, Huntington Disease, biology.protein, Spinocerebellar ataxia, Female, Alzheimer's disease, TATA-binding protein, Peptides, Trinucleotide Repeat Expansion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6e472ee75c180b2a2a3507826c5d0d
https://doi.org/10.1016/j.molbrainres.2004.03.018

المؤلفون: Mike Dragunow, Mark I. Rees, Willeke M. C. van Roon-Mom, Richard L.M. Faull, Michael John Owen, Marcy E. MacDonald, Lesley Jones, Greg T. Sutherland, Suzanne J. Reid, Matthew J. During, Russell G. Snell

المصدر: Neurobiology of Disease, Vol 13, Iss 1, Pp 37-45 (2003)

مصطلحات موضوعية: Genetics, Binding protein, Neurodegeneration, RNA, Biology, medicine.disease, lcsh:RC321-571, Neurology, Transcription (biology), medicine, Spinocerebellar ataxia, Cellular model, Allele, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deb51d241b59d514d4ae2390649a2b4
https://doi.org/10.1016/s0969-9961(03)00014-7