المؤلفون: Catarina Garcia, Vera M. S. Isca, Filipe Pereira, Carlos M. Monteiro, Epole Ntungwe, Francisco Sousa, Jelena Dinic, Suvi Holmstedt, Amílcar Roberto, Ana Díaz-Lanza, Catarina P. Reis, Milica Pesic, Nuno R. Candeias, Ricardo J. Ferreira, Noélia Duarte, Carlos A. M. Afonso, Patrícia Rijo

المصدر: Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: Plectranthus, Diterpenes, Royleanones, stability, Artemia salina, P-pg activity, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2020.557789/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/e0c57d17a6814473b2b968463276ad86

المؤلفون: Suvi Holmstedt (8582640), Alexander Efimov (1683016), Nuno R. Candeias (2086225)

مصطلحات موضوعية: Biochemistry, Medicine, Molecular Biology, Sociology, Developmental Biology, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, reaction conditions, Divergent Synthesis, Silyl Group Migrations, silicon substituents, African ant Crematogaster nigriceps, vitamin D receptor modulator VS -105, synthesis, quinic acid-derived cyclitol

Relation: https://figshare.com/articles/journal_contribution/_i_O_O_i_-Silyl_Group_Migrations_in_Quinic_Acid_Derivatives_An_Opportunity_for_Divergent_Synthesis/14384331

الاتاحة: https://doi.org/10.1021/acs.orglett.1c00755.s001

المؤلفون: Nuno R. Candeias, Suvi Holmstedt, Alexander Efimov

المساهمون: Tampere University, Materials Science and Environmental Engineering

المصدر: Organic Letters. 23:3083-3087

مصطلحات موضوعية: Silylation, 010405 organic chemistry, Chemistry, Stereochemistry, Cyclitol, Metabolite, 116 Chemical sciences, Organic Chemistry, Total synthesis, Quinic acid, 010402 general chemistry, 01 natural sciences, Biochemistry, ANT, 0104 chemical sciences, chemistry.chemical_compound, Group (periodic table), Physical and Theoretical Chemistry, Divergent synthesis

وصف الملف: fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c125417702dbc76e30ebb6df73eccb
https://doi.org/10.1021/acs.orglett.1c00755

المؤلفون: Vera M. S. Isca, Carlos M. Monteiro, Jelena Dinić, Carlos A. M. Afonso, Suvi Holmstedt, Patrícia Rijo, Catarina Garcia, Nuno R. Candeias, Vânia André, Ricardo J. Ferreira, Daniel J. V. A. dos Santos, Milica Pešić

المصدر: ACS Medicinal Chemistry Letters

مصطلحات موضوعية: Cancer chemotherapy, Plectranthus, macromolecular substances, Multidrug resistance, Molecular dynamics, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Royleanone derivatives, Drug Discovery, P-gp inhibition, Abietane, Royleanone, P-glycoprotein Inhibitor, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, biology.organism_classification, 3. Good health, 0104 chemical sciences, Multiple drug resistance, 010404 medicinal & biomolecular chemistry, Molecular docking

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefac606a2b82c4587a5db57e5c8c791
https://doi.org/10.1021/acsmedchemlett.9b00642

المؤلفون: Nga Nguyen, Suvi Holmstedt, Ana S. Macedo, Pedro Fonte, Patrícia Rijo, Akshaya Murugesan, Meenakshisundaram Kandhavelu, Kenna C Brown, Nuno R. Candeias, Olli Yli-Harja, Alisa Koivuporras

المصدر: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: Cytotoxicity, In vitro cytotoxicity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Nanoparticle, Polyol, Quinic acid, Drug Discovery, medicine, Pharmacology & Pharmacy, 030304 developmental biology, Pharmacology, chemistry.chemical_classification, 0303 health sciences, Chemistry, PLGA, medicine.disease, Biochemistry, 030220 oncology & carcinogenesis, Molecular Medicine, Chemotherapeutic drugs, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4955e0973718717d54bd396afdeff2e

المؤلفون: Akshaya, Murugesan, Suvi, Holmstedt, Kenna C, Brown, Alisa, Koivuporras, Ana S, Macedo, Nga, Nguyen, Pedro, Fonte, Patrícia, Rijo, Olli, Yli-Harja, Nuno R, Candeias, Meenakshisundaram, Kandhavelu

المصدر: Future medicinal chemistry. 12(21)

مصطلحات موضوعية: Structure-Activity Relationship, Dose-Response Relationship, Drug, Drug Design, Quinic Acid, Tumor Cells, Cultured, Humans, Antineoplastic Agents, Apoptosis, Drug Screening Assays, Antitumor, Glioblastoma, Cell Proliferation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::177ec8d76d285e5193e5c2a0982cbe2e
https://pubmed.ncbi.nlm.nih.gov/33124467

المؤلفون: Catarina, Garcia, Vera M S, Isca, Filipe, Pereira, Carlos M, Monteiro, Epole, Ntungwe, Francisco, Sousa, Jelena, Dinic, Suvi, Holmstedt, Amílcar, Roberto, Ana, Díaz-Lanza, Catarina P, Reis, Milica, Pesic, Nuno R, Candeias, Ricardo J, Ferreira, Noélia, Duarte, Carlos A M, Afonso, Patrícia, Rijo

المصدر: Frontiers in Pharmacology

مصطلحات موضوعية: Pharmacology, Royleanones, Plectranthus, Diterpenes, stability, P-pg activity, Original Research, Artemia salina

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::acc7bba9113792223491b690e0872bb6
https://pubmed.ncbi.nlm.nih.gov/33364937

المؤلفون: Alisa Koivuporras, Arto Valkonen, Suvi Holmstedt, Lijo George, Nuno R. Candeias

مصطلحات موضوعية: Hydrosilylation, 010402 general chemistry, 01 natural sciences, Biochemistry, Silyl ether, chemistry.chemical_compound, redox reactions, Physical and Theoretical Chemistry, hapetus-pelkistysreaktio, orgaaniset yhdisteet, eetterit, kemiallinen synteesi, 010405 organic chemistry, reaction products, Organic Chemistry, hydrosilylation, Quinic acid, Combinatorial chemistry, 0104 chemical sciences, bond cleavage, ethers, chemistry, Stereoselectivity, Selectivity, Divergent synthesis, Derivative (chemistry), Vicinal

وصف الملف: application/pdf; fulltext

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c754f3b01bad8615664b996c9180bc8
http://urn.fi/URN:NBN:fi:jyu-202102011373

المؤلفون: Catarina Garcia, Vera M. S. Isca, Filipe Pereira, Carlos M. Monteiro, Epole Ntungwe, Francisco Sousa, Jelena Dinic, Suvi Holmstedt, Amílcar Roberto, Ana Díaz-Lanza, Catarina P. Reis, Milica Pesic, Nuno R. Candeias, Ricardo J. Ferreira, Noélia Duarte, Carlos A. M. Afonso, Patrícia Rijo

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, Plectranthus, Diterpenes, Royleanones, stability, Artemia salina, P-pg activity

Relation: https://figshare.com/articles/dataset/datasheet1_Royleanone_Derivatives_From_Plectranthus_spp_as_a_Novel_Class_of_P-Glycoprotein_Inhibitors_pdf/13246310

الاتاحة: https://doi.org/10.3389/fphar.2020.557789.s001
https://figshare.com/articles/dataset/datasheet1_Royleanone_Derivatives_From_Plectranthus_spp_as_a_Novel_Class_of_P-Glycoprotein_Inhibitors_pdf/13246310