المؤلفون: Rainer Hubmann, Susanne Schnabl, Mohammad Araghi, Christian Schmidl, André F. Rendeiro, Martin Hilgarth, Dita Demirtas, Farghaly Ali, Philipp B. Staber, Peter Valent, Christoph Zielinski, Ulrich Jäger, Medhat Shehata

المصدر: Cells, Vol 9, Iss 6, p 1484 (2020)

مصطلحات موضوعية: chronic lymphocytic leukemia (CLL), NOTCH2, NOTCH3, FCER2 (CD23), NR4A1, gliotoxin, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/6/1484; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/9fa36cc823a740d693e92d4114a3a329

المؤلفون: Rainer Hubmann, Wolfgang Sieghart, Susanne Schnabl, Mohammad Araghi, Martin Hilgarth, Marlies Reiter, Dita Demirtas, Peter Valent, Christoph Zielinski, Ulrich Jäger, Medhat Shehata

المصدر: Frontiers in Pharmacology, Vol 8 (2017)

مصطلحات موضوعية: NOTCH2, gliotoxin, γ-secretase inhibitors, melanoma, hepatocellular carcinoma, pancreas carcinoma, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fphar.2017.00319/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/5cb20fc27d864c0c9002935297f751e2

المؤلفون: Philipp B. Staber, Charles Joly-Beauparlant, Medhat Shehata, Joanie Vaillancourt, Éric Lévesque, Eric P. Allain, Dita Demirtas, Michèle Rouleau, Ulrich Jäger, Chantal Guillemette, Katrina Vanura, Sophie Tremblay, Vincent Bat, Rainer Hubmann, Patrick Caron, Arnaud Droit, Véronique Turcotte, Lyne Villeneuve, Trang Le, Susanne Schnabl, Adrien Labriet

المصدر: British Journal of Cancer

مصطلحات موضوعية: Drug, Cancer Research, Glucuronosyltransferase, media_common.quotation_subject, Cell, Predictive markers, Article, Transcriptome, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, 030304 developmental biology, media_common, Haematological cancer, 0303 health sciences, biology, business.industry, medicine.disease, 3. Good health, Fludarabine, Leukemia, medicine.anatomical_structure, Oncology, chemistry, 030220 oncology & carcinogenesis, Ibrutinib, biology.protein, Cancer research, business, Idelalisib, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b582252723066bbd9a3c1107fbd262
https://doi.org/10.1038/s41416-020-0887-6

المؤلفون: Peter Valent, Philipp B. Staber, Medhat Shehata, Dita Demirtas, Farghaly Ali, Martin Hilgarth, Rainer Hubmann, Ulrich Jäger, André F. Rendeiro, Mohammad Araghi, Susanne Schnabl, Christian Schmidl, Christoph C. Zielinski

المصدر: Cells
Volume 9
Issue 6
Cells, Vol 9, Iss 1484, p 1484 (2020)

مصطلحات موضوعية: 0301 basic medicine, Male, RO4929097, Chronic lymphocytic leukemia, FCER2 (CD23), Cell, binary cell fate decision, NR4A1, Apoptosis, chemistry.chemical_compound, 0302 clinical medicine, NOTCH2, NOTCH3, hemic and lymphatic diseases, Nuclear Receptor Subfamily 4, Group A, Member 1, Tumor Cells, Cultured, Receptor, Notch2, Regulatory Elements, Transcriptional, CD5+ B-cell homeostasis, lcsh:QH301-705.5, Receptor, Notch3, Aged, 80 and over, Gliotoxin, Chemistry, General Medicine, ATAC-seq, Middle Aged, Chromatin, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Signal Transduction, Adult, endocrine system, gliotoxin, Cell Survival, Notch signaling pathway, Down-Regulation, Antineoplastic Agents, Article, 03 medical and health sciences, γ-secretase inhibitors, Downregulation and upregulation, chronic lymphocytic leukemia (CLL), medicine, Humans, Lectins, C-Type, Viability assay, RNA, Messenger, Aged, Dose-Response Relationship, Drug, Receptors, IgE, positive/negative selection, Benzazepines, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, 030104 developmental biology, lcsh:Biology (General), Cancer research, Amyloid Precursor Protein Secretases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9bd0dcbb71596a8d6e2867de4d8fb4
http://europepmc.org/articles/PMC7348714

المؤلفون: Jaromír Vašíček, Peter Chrenek, Susanne Schnabl, Martin Hilgarth, Ulrich Jäger, Medhat Shehata, Rainer Hubmann, Miroslav Bauer

المصدر: Biotechnology Progress. 34:1278-1289

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Antigens, CD34, Monoclonal antibody, Antibodies, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, AC133 Antigen, biology, medicine.diagnostic_test, Chemistry, Hematopoietic stem cell, Cell sorting, Flow Cytometry, Hematopoietic Stem Cells, Molecular biology, 030104 developmental biology, medicine.anatomical_structure, Polyclonal antibodies, 030220 oncology & carcinogenesis, biology.protein, Rabbits, Antibody, Stem cell, Clone (B-cell biology), Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5facd579461d0e02a6bdba743828c154
https://doi.org/10.1002/btpr.2659

المؤلفون: Michaela Gruber, Martin Hilgarth, Stefan Kubicek, Edit Porpaczy, Christian Schmidl, Rainer Hubmann, Nikolaus Krall, Anna Ringler, Philipp B. Staber, Christina Taubert, Mohammad Araghi, Dita Demirtas, Gregory I. Vladimer, Oscar Lopez de la Fuente, Medhat Shehata, Giulio Superti-Furga, Berend Snijder, Gregor Hoermann, Tea Pemovska, Cathrin Skrabs, Thomas Krausgruber, Kathrin Runggatscher, Ulrich Jäger, Susanne Schnabl, André F. Rendeiro, Christoph Bock

المصدر: Nature Chemical Biology, 15 (3)
Nature Chemical Biology

مصطلحات موضوعية: Epigenomics, Drug, Chronic lymphocytic leukemia, media_common.quotation_subject, Cell Cycle Proteins, Protein Serine-Threonine Kinases, PLK1, Article, Epigenesis, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Piperidines, Proto-Oncogene Proteins, Agammaglobulinaemia Tyrosine Kinase, medicine, Humans, Bruton's tyrosine kinase, Epigenetics, Protein Kinase Inhibitors, Molecular Biology, 030304 developmental biology, media_common, 0303 health sciences, biology, business.industry, Adenine, TOR Serine-Threonine Kinases, 030302 biochemistry & molecular biology, Cell Biology, Epigenome, Protein-Tyrosine Kinases, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Chromatin, 3. Good health, Drug Combinations, Leukemia, Pyrimidines, chemistry, Drug Resistance, Neoplasm, Ibrutinib, Cancer research, biology.protein, Pyrazoles, Single-Cell Analysis, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8ec57ac57f9b814e4af6f250e81781
https://hdl.handle.net/20.500.11850/328366

المؤلفون: Susanne Schnabl, Miroslav Bauer, Martin Hilgarth, Maria Tomkova, Andrej Baláži, Medhat Shehata, Lucia Olexikova, Alexander V. Makarevich, Barbora Kulíková, Jaromír Vašíček, Rainer Hubmann, Peter Chrenek, Jozef Čurlej, Michal Kovac

المصدر: New biotechnology. 54

مصطلحات موضوعية: 0106 biological sciences, Bioengineering, Vimentin, Bone Marrow Cells, 01 natural sciences, Cryopreservation, 03 medical and health sciences, SOX2, Antigens, CD, 010608 biotechnology, medicine, Animals, CD90, RNA, Messenger, Molecular Biology, 030304 developmental biology, Biological Specimen Banks, 0303 health sciences, biology, Reverse Transcriptase Polymerase Chain Reaction, CD44, Mesenchymal stem cell, Mesenchymal Stem Cells, General Medicine, Cell biology, medicine.anatomical_structure, Phenotype, biology.protein, CD146, Bone marrow, Rabbits, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07542ad4bacd937bf7564e308364922
https://pubmed.ncbi.nlm.nih.gov/31400479

المؤلفون: Gregory I. Vladimer, Christoph Schmidl, Andre Renderio, Susanne Schnabl, Medhat Shehata, Giulio Superti-Furga, Ulrich Jäger, Christoph Bock

المصدر: Cancer Research. 79:319-319

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ccdf5571164a01d81fbd5abb7805cb3
https://doi.org/10.1158/1538-7445.am2019-319

المؤلفون: Ulrich Jäger, Katrina Vanura, Susanne Schnabl, Georg Hopfinger, E. Porpaczy, Martin Bilban, Stephan Stilgenbauer, Michael Hallek, Rainer Hubmann, Karin Eigenberger, Dita Demirtas, Martin Hilgarth, Josef D. Schwarzmeier, Medhat Shehata, Ilse Schwarzinger, Alexander Gaiger, Christa Fonatsch, Alexander W. Hauswirth, Daniel Heintel

المصدر: Leukemia. 24:2122-2127

مصطلحات موضوعية: Male, Cancer Research, business.industry, Gene Expression Profiling, Integrin alpha4, Chronic lymphocytic leukemia, Hematology, Middle Aged, Antigens, CD20, medicine.disease, Bioinformatics, Leukemia, Lymphocytic, Chronic, B-Cell, Gene expression profiling, Phosphatidylinositol 3-Kinases, Hyaluronan Receptors, Oncology, Cancer research, Humans, Medicine, Female, Identification (biology), business, Biomarkers, Aged, Oligonucleotide Array Sequence Analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b291531d8dd22ce42a98c14981aaa9
https://doi.org/10.1038/leu.2010.220

المؤلفون: Christoph C. Zielinski, Josef D. Schwarzmeier, Andrea Hoelbl, Ulrich Jaeger, Elena Ponath, Susanne Schnabl, Medhat Shehata, Alexander Gaiger, Sigrun Badrnya, Claudia Lehner, Rainer Hubmann, Markus Duechler, Dita Demirtas, Martin Hilgarth

المصدر: Blood. 116:2513-2521

مصطلحات موضوعية: Stromal cell, Chronic lymphocytic leukemia, Immunology, Apoptosis, Bone Marrow Cells, Biochemistry, medicine, Humans, PTEN, Tensin, Casein Kinase II, Protein kinase B, Cells, Cultured, PI3K/AKT/mTOR pathway, Tumor microenvironment, biology, PTEN Phosphohydrolase, Cell Biology, Hematology, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, biology.protein, Cancer research, Phosphatidylinositol 3-Kinase, Stromal Cells, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8f79118ce7cbe2adaf06597679060a
https://doi.org/10.1182/blood-2009-10-248054

المؤلفون: Medhat Shehata, Zeev Estrov, William Plunkett, Rong Chen, Susanne Schnabl, Antonina V. Kurtova, Maite P. Quiroga, Kumudha Balakrishnan, William G. Wierda, Mariela Sivina, Neil E. Kay, Varsha Gandhi, Wei Ding, Michael J. Keating, Jan A. Burger, Ulrich Jäger

المصدر: Blood. 114:4441-4450

مصطلحات موضوعية: Programmed cell death, Stromal cell, Chronic lymphocytic leukemia, Blotting, Western, Immunology, Antineoplastic Agents, Apoptosis, Bone Marrow Cells, Cell Communication, Biology, Biochemistry, Mice, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, Cell Adhesion, medicine, Animals, Humans, Cell adhesion, neoplasms, Cells, Cultured, Lymphoid Neoplasia, Mesenchymal stem cell, Cell Biology, Hematology, Flow Cytometry, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Coculture Techniques, Leukemia, medicine.anatomical_structure, Drug Resistance, Neoplasm, Cell culture, Cancer research, Bone marrow, Stromal Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf806017d8c813fa343a6f464ca6682e
https://doi.org/10.1182/blood-2009-07-233718

المؤلفون: Ulrich Jaeger, Susanne Schnabl, Thomas Krausgruber, Philipp B. Staber, Gregory I. Vladimer, Christian Schmidl, Edit Porpaczy, Medhat Shehata, Dita Demirtas, Berend Snijder, Michaela Gruber, Tea Pemovska, Stefan Kubicek, Andre Renderio, Giulio Superti-Furga, Oscar Lopez de la Fuente, Rainer Hubmann, Gregor Hoermann, Martin Hilgrath, Christoph Bock, Anna Ringler, Cathrin Skrabs, Mohammad Araghi, Nikolaus Krall

المصدر: Blood. 130:800-800

مصطلحات موضوعية: Oncology, medicine.medical_specialty, biology, business.industry, Bortezomib, Venetoclax, Chronic lymphocytic leukemia, Immunology, Volasertib, Cell Biology, Hematology, medicine.disease, Biochemistry, Carfilzomib, chemistry.chemical_compound, chemistry, Ibrutinib, Internal medicine, Proteasome inhibitor, medicine, biology.protein, Bruton's tyrosine kinase, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64c610d77ba1721632dfc75928c42c8a
https://doi.org/10.1182/blood.v130.suppl_1.800.800

المؤلفون: Susanne Schnabl, Martin Hilgarth, Elena Ponath, Marlies Reiter, Wolfgang Sieghart, Medhat Shehata, Peter Valent, Ulrich Jäger, Dita Demirtas, Rainer Hubmann, Christoph C. Zielinski

المصدر: British journal of haematology. 160(5)

مصطلحات موضوعية: Male, Transcriptional Activation, endocrine system, Proteasome Endopeptidase Complex, Stromal cell, endocrine system diseases, DNA Mutational Analysis, Apoptosis, Biology, Transactivation, chemistry.chemical_compound, Inhibitory Concentration 50, Gliotoxin, immune system diseases, hemic and lymphatic diseases, Cell Line, Tumor, Nuclear Receptor Subfamily 4, Group A, Member 1, Tumor Cells, Cultured, Humans, Viability assay, Receptor, Notch2, Receptor, Notch3, Aged, Regulation of gene expression, Aged, 80 and over, Receptors, Notch, Kinase, Gene Expression Regulation, Leukemic, CD23, NF-kappa B, Hematology, Middle Aged, Leukemia, Lymphocytic, Chronic, B-Cell, Coculture Techniques, Neoplasm Proteins, chemistry, Cell culture, Depression, Chemical, Immunology, Cancer research, Female, Stromal Cells, Immunoglobulin Heavy Chains, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189328843c00e78a43f84b6a3c33bf75
https://pubmed.ncbi.nlm.nih.gov/23278106

المؤلفون: Ulrich Jäger, Andrea Hölbl, Martin Hilgarth, Susanne Schnabl, Josef D. Schwarzmeier, Katrina Vanura, Thomas Look, Dieter Mitteregger, Dita Demirtas, Medhat Shehata, Peter Valent, Rainer Hubmann, Markus Düchler, Trang Le

المصدر: British journal of haematology. 148(6)

مصطلحات موضوعية: endocrine system, endocrine system diseases, Chronic lymphocytic leukemia, Biology, chemistry.chemical_compound, Interferon-gamma, immune system diseases, Antigens, Neoplasm, hemic and lymphatic diseases, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Humans, Receptor, Notch2, Protein kinase C, Activator (genetics), Receptors, IgE, CD23, Hematology, medicine.disease, Prognosis, Leukemia, Lymphocytic, Chronic, B-Cell, Neoplasm Proteins, Leukemia, Protein Kinase C-delta, chemistry, Cancer research, Phorbol, Tetradecanoylphorbol Acetate, RNA Interference, Signal transduction, Rottlerin, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a3cb19a8a5ee7af7fd457053e6a092
https://pubmed.ncbi.nlm.nih.gov/19995395

المؤلفون: Martin Hilgarth, Medhat Shehata, Susanne Schnabl, Katrina Vanura, Dita Demirtas, Ulrich Jäger, Rainer Hubmann, Josef D. Schwarzmeier, Trang Le

المصدر: Cytokine. 43:286-287

مصطلحات موضوعية: CD20, biology, Chemistry, Chronic lymphocytic leukemia, Immunology, CD23, Hematology, medicine.disease, Biochemistry, Molecular biology, medicine, biology.protein, Immunology and Allergy, Molecular Biology, Protein Kinase C-delta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d245e59ad56ecdc4f371d8925b31ba33
https://doi.org/10.1016/j.cyto.2008.07.261

المؤلفون: Susanne Schnabl, Marlies Reiter, Rainer Hubmann, Dita Demirtas, Martin Hilgarth, Ulrich Jäger, Elena Ponath, Medhat Shehata

المصدر: Blood. 120:3919-3919

مصطلحات موضوعية: Stromal cell, Gliotoxin, Immunology, CD23, Notch signaling pathway, Cell Biology, Hematology, Biology, Biochemistry, Cell biology, Transactivation, chemistry.chemical_compound, chemistry, Downregulation and upregulation, Apoptosis, hemic and lymphatic diseases, MCL1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ea7c6e1a41df408366c7fea8257558f
https://doi.org/10.1182/blood.v120.21.3919.3919

المؤلفون: Medhat Shehata, Ulrich Jäger, Susanne Schnabl, Dita Demirtas, Martin Hilgarth, Eva Fuchs, Marlies Reiter, Elena Ponath, Rainer Hubmann

المصدر: Blood. 120:3916-3916

مصطلحات موضوعية: Stromal cell, Immunology, food and beverages, Cell Biology, Hematology, Biology, Biochemistry, Molecular biology, chemistry.chemical_compound, Cell killing, chemistry, Apoptosis, Propidium iodide, Viability assay, Annexin A5, Protein kinase B, PI3K/AKT/mTOR pathway

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1808804a1b006c2185ff818127d3ca33
https://doi.org/10.1182/blood.v120.21.3916.3916

المؤلفون: Dita Demirtas, Martin Hilgarth, Medhat Shehata, Susanne Schnabl, Rainer Hubmann, Marlies Reiter, Ulrich Jäger, Elena Ponath, Christoph C. Zielinski

المصدر: Blood. 118:4609-4609

مصطلحات موضوعية: Stromal cell, Gliotoxin, Chemistry, Chronic lymphocytic leukemia, Immunology, Notch signaling pathway, CD23, Cell Biology, Hematology, medicine.disease, Biochemistry, chemistry.chemical_compound, PRKCD, Apoptosis, Cell culture, hemic and lymphatic diseases, Cancer research, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2720456ff9eb77d1e727d05beb5621bc
https://doi.org/10.1182/blood.v118.21.4609.4609

المؤلفون: Sabine Strommer, Volker Wachek, Martin Hilgarth, Elina Ponath, Ulrich Jaeger, Ekaterina Brynzak, Katrina Vanura, Susanne Schnabl, Alexander W. Hauswirth, Christoph C. Zielinski, Medhat Shehata, Rainer Hubmann, Alexander Gaiger, Berthold Streubel, Dita Demirtas, Peter Valent, Josef D. Schwarzmeier

المصدر: Blood. 116:2433-2433

مصطلحات موضوعية: Stromal cell, Chronic lymphocytic leukemia, Immunology, CD34, Hematopoietic stem cell, Cell Biology, Hematology, Biology, Stem cell marker, medicine.disease, Biochemistry, Molecular biology, Leukemia, medicine.anatomical_structure, immune system diseases, hemic and lymphatic diseases, medicine, Bone marrow, Stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8056b485a1711f0d276fcc7458819c9f
https://doi.org/10.1182/blood.v116.21.2433.2433

المؤلفون: Steve Hughes, Susanne Schnabl, Dita Demirtas, Karin Fleiss, Martin Hilgarth, Christoph C. Zielinski, Medhat Shehata, Martin Bilban, Stefanie Tauber, Alexander Gaiger, Ulrich Jaeger, Josef D. Schwarzmeier, Elena Ponath, Sigrun Badrnya, Ann Maclaren, Rainer Hubmann

المصدر: Web of Science

مصطلحات موضوعية: Stromal cell, biology, Lumiliximab, Chronic lymphocytic leukemia, Immunology, CD23, Cell Biology, Hematology, medicine.disease, Biochemistry, CD19, Apoptosis, hemic and lymphatic diseases, medicine, Cancer research, biology.protein, Viability assay, CD5, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d3d75694344bef67935244b0a6621f
https://doi.org/10.1182/blood.v114.22.2371.2371