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1
المؤلفون: Belinda J. Michell, Christine A. Seers, Susanne C. Feil, Keith J. Cross, Michael W. Parker, Michael A. Gorman, Eric C. Reynolds, N. Laila Huq
المصدر: Protein Science. 24:162-166
مصطلحات موضوعية: Protease, biology, Chemistry, medicine.medical_treatment, Virulence, biology.organism_classification, Biochemistry, Cysteine protease, Virulence factor, Microbiology, Bacterial adhesin, Gingipain, stomatognathic diseases, medicine, Molecular Biology, Porphyromonas gingivalis, Pathogen
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2
المصدر: Journal of Molecular Biology. 426:785-792
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Streptococcus pyogenes, Amino Acid Motifs, Bacterial Toxins, Biology, Crystallography, X-Ray, Cholesterol-dependent cytolysin, medicine.disease_cause, Hemolysin Proteins, Article, Cell membrane, Protein structure, Bacterial Proteins, Structural Biology, medicine, Molecular Biology, Pore-forming toxin, Cell Membrane, Cholesterol, Membrane, medicine.anatomical_structure, Biochemistry, Streptolysins, Biophysics, Streptolysin, Protein Multimerization
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3
المؤلفون: Craig J. Morton, Susanne C. Feil, Sara L. Lawrence, Rodney K. Tweten, Adam J. Ratner, Terrence D. Mulhern, Michael W. Parker, Michael J. Kuiper, Michael A. Gorman
المصدر: Structure (London, England : 1993). 24(9)
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, alpha-Helical, Cell, Amino Acid Motifs, Bacterial Toxins, Beta sheet, Gene Expression, chemical and pharmacologic phenomena, CD59 Antigens, Plasma protein binding, Biology, Molecular Dynamics Simulation, Crystallography, X-Ray, Article, 03 medical and health sciences, Protein structure, Bacterial Proteins, Bacteriocins, X-Ray Diffraction, Structural Biology, Scattering, Small Angle, medicine, Escherichia coli, Humans, Protein Interaction Domains and Motifs, Binding site, Cloning, Molecular, Receptor, Molecular Biology, Pore-forming toxin, Binding Sites, Recombinant Proteins, 3. Good health, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Cholesterol, Biochemistry, Mutation, Protein Conformation, beta-Strand, Protein Multimerization, Bacterial outer membrane, Protein Binding
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4
المؤلفون: T. John Martin, David T. Manallack, Nancy C. Hancock, Patricia W. M. Ho, Ian G. Jennings, Jessica K. Holien, Hooi-Ling Ng, Craig J. Morton, Susanne C. Feil, Jacob L. Nankervis, Philip E. Thompson, Mark Frazzetto, Michael W. Parker, Zhaohua Zheng
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:7089-7093
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Thiophenes, Crystal structure, Plasma protein binding, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, Catalytic Domain, Drug Discovery, Hydrolase, Thiophene, Binding site, Molecular Biology, chemistry.chemical_classification, Binding Sites, Parathyroid hormone receptor, Organic Chemistry, Cyclic Nucleotide Phosphodiesterases, Type 4, Enzyme, chemistry, Molecular Medicine, Phosphodiesterase 4 Inhibitors, Gewald reaction, Protein Binding
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5
المؤلفون: Susanne C. Feil, Guido Hansen, Glenn A. Powers, Michael W. Parker, Mary Catherine Pearce, Stephen P. Bottomley
المصدر: Journal of Molecular Biology. 403:459-467
مصطلحات موضوعية: Models, Molecular, Protein Folding, Conformational change, biology, Protein Conformation, Chemistry, Protein Data Bank (RCSB PDB), Energy landscape, Serpin, Crystallography, X-Ray, Alpha 1-antichymotrypsin, Kinetics, Crystallography, Protein structure, Structural Biology, Biophysics, biology.protein, Native state, Humans, Thermodynamics, Protein folding, Molecular Biology, Serpins
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6
المؤلفون: Michael Bieri, Malcolm J. McConville, James Pyke, Yee-Foong Mok, Susanne C. Feil, Craig J. Morton, Wai Yee Low, Paul R. Gooley, Charles Robin, Hooi Ling Ng, Michael W. Parker, Michael A. Gorman, Philip J. Batterham
المصدر: Journal of Molecular Biology. 399:358-366
مصطلحات موضوعية: Insecticides, Magnetic Resonance Spectroscopy, animal structures, Protein Conformation, Stereochemistry, Crystallography, X-Ray, DDT, chemistry.chemical_compound, Protein structure, Structural Biology, parasitic diseases, Melanogaster, Animals, Binding site, Molecular Biology, Glutathione Transferase, Binding Sites, biology, Active site, Glutathione, biology.organism_classification, Drosophila melanogaster, Glutathione S-transferase, chemistry, Biochemistry, Inactivation, Metabolic, biology.protein, Heteronuclear single quantum coherence spectroscopy
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7
المؤلفون: Sara L. Lawrence, Michael W. Parker, Rodney K. Tweten, Terrence D. Mulhern, Susanne C. Feil, Craig J. Morton, Kristin R. Wade, Allison J. Farrand, Michael A. Gorman
المصدر: Scientific Reports
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Carbohydrates, Plasma protein binding, Biology, Cholesterol-dependent cytolysin, medicine.disease_cause, Crystallography, X-Ray, Virulence factor, Article, Microbiology, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Protein structure, Bacterial Proteins, Streptococcus pneumoniae, medicine, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Pneumolysin, Binding Sites, Small molecule, 3. Good health, Molecular Docking Simulation, Solutions, Membrane, Mutation, Streptolysins, Protein Multimerization, Mannose, 030217 neurology & neurosurgery, Protein Binding
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8
المؤلفون: David Stapleton, Bruce E. Kemp, Susanne C. Feil, Bryce J. W. van Denderen, Galina Polekhina, Abhilasha Gupta, Michael W. Parker
المصدر: Structure. 13:1453-1462
مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, Oligosaccharides, AMP-Activated Protein Kinases, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Spectrum Analysis, Raman, Binding, Competitive, chemistry.chemical_compound, Leucine, Multienzyme Complexes, Structural Biology, Catalytic Domain, Carbohydrate Conformation, Glycogen branching enzyme, Animals, Amino Acid Sequence, Phosphorylase kinase, Glycogen synthase, Glucans, Molecular Biology, Glycogen binding, Binding Sites, Sequence Homology, Amino Acid, biology, Glycogen, beta-Cyclodextrins, Tryptophan, Water, AMPK, Protein Structure, Tertiary, Rats, Protein Subunits, Glucose, Liver, chemistry, Biochemistry, Mutation, Mutagenesis, Site-Directed, biology.protein, Protein Binding, Binding domain, Starch binding
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9
المؤلفون: Michael W. Parker, Susanne C. Feil
المصدر: Progress in Biophysics and Molecular Biology. 88:91-142
مصطلحات موضوعية: Models, Molecular, Protein Folding, Pore-forming toxin, Membrane insertion, Stereochemistry, Chemistry, Cell Membrane, Biophysics, Membrane Proteins, Porins, Crystallography, X-Ray, Pore forming protein, Order (biology), Membrane, Protein folding, Molecular Biology, Function (biology), Toxins, Biological
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10
المؤلفون: David Stapleton, Abhilasha Gupta, Paul O'Donnell, Michael W. Parker, Susanne C. Feil, Galina Polekhina
المصدر: Acta Crystallographica Section F Structural Biology and Crystallization Communications. 61:39-42
مصطلحات موضوعية: Protein subunit, Biophysics, AMP-Activated Protein Kinases, Protein Serine-Threonine Kinases, Biochemistry, chemistry.chemical_compound, X-Ray Diffraction, AMP-activated protein kinase, Multienzyme Complexes, Structural Biology, Genetics, Animals, Cloning, Molecular, Binding site, Selenomethionine, Protein kinase A, DNA Primers, Glycogen binding, Binding Sites, biology, Glycogen, Kinase, AMPK, Condensed Matter Physics, Peptide Fragments, Recombinant Proteins, Rats, Protein Subunits, chemistry, Crystallization Communications, biology.protein, Crystallization, Protein Kinases
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11
المؤلفون: Michael A, Gorman, Christine A, Seers, Belinda J, Michell, Susanne C, Feil, N Laila, Huq, Keith J, Cross, Eric C, Reynolds, Michael W, Parker
المصدر: Protein science : a publication of the Protein Society. 24(1)
مصطلحات موضوعية: Models, Molecular, stomatognathic diseases, Cysteine Endopeptidases, Protein Conformation, Bacteroidaceae Infections, Gingipain Cysteine Endopeptidases, Humans, Oral Health, Adhesins, Bacterial, Crystallography, X-Ray, Protein Structure Reports, Porphyromonas gingivalis
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12
المؤلفون: Konrad Beyreuther, Roberto Cappai, William J. McKinstry, Susanne C. Feil, Lars Hesse, Anna Henry, Colin L. Masters, Denise Galatis, Jamie Rossjohn, Michael W. Parker, Gerd Multhaup
المصدر: Nature Structural Biology. 6:327-331
مصطلحات موضوعية: biology, Neurite, Chemistry, P3 peptide, medicine.disease, Biochemistry, Cell biology, Biochemistry of Alzheimer's disease, Protein structure, Structural Biology, mental disorders, Genetics, biology.protein, Amyloid precursor protein, medicine, Growth factor-like domain, Alzheimer's disease, Amyloid precursor protein secretase
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13
المؤلفون: Jamie Rossjohn, Susanne C. Feil, Michele Masulli, Michael W. Parker, Nerino Allocati, Galina Polekhina, Carmine Di Ilio
المصدر: Structure. 6(6):721-734
مصطلحات موضوعية: Protein Folding, Cellular detoxification, Molecular Sequence Data, Crystallography, X-Ray, Conserved sequence, Evolution, Molecular, Thioredoxins, Bacterial Proteins, Structural Biology, evolution, Transferase, Amino Acid Sequence, Disulfides, Peptide sequence, cysteine chemistry, Proteus mirabilis, Molecular Biology, Conserved Sequence, X-ray crystallography, Glutathione Transferase, chemistry.chemical_classification, Binding Sites, biology, Sequence Homology, Amino Acid, Drug Resistance, Microbial, thioredoxin, Glutathione, Enzyme, chemistry, Biochemistry, biology.protein, Bacterial glutathione transferase, Thioredoxin, Cysteine
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14
المؤلفون: G van der Goot, Demetrius Tsernoglou, Michael W. Parker, J T Buckley, William J. McKinstry, Jamie Rossjohn, Susanne C. Feil
المصدر: Journal of Structural Biology. 121:92-100
مصطلحات موضوعية: Models, Molecular, Pore Forming Cytotoxic Proteins, Cell Membrane Permeability, Polymers, Protein Conformation, Bacterial Toxins, Molecular Sequence Data, Aerolysin, Beta sheet, Sequence alignment, Plasma protein binding, Biology, Crystallography, X-Ray, Ion Channels, Protein Structure, Secondary, Hemolysin Proteins, Structure-Activity Relationship, Protein structure, Structural Biology, Amino Acid Sequence, Protein Precursors, Peptide sequence, Plant Proteins, Sequence Homology, Amino Acid, Cytotoxins, Transmembrane protein, Biochemistry, Dimerization, Sequence Alignment, Function (biology), Protein Binding
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15
المؤلفون: Susanne C. Feil, S M Raja, Jamie Rossjohn, J T Buckley, Michael W. Parker, F. G. van der Goot, K L Nelson
المصدر: Biochemistry, Vol. 37, No 2 (1998) pp. 741-746
مصطلحات موضوعية: Models, Molecular, Pore Forming Cytotoxic Proteins, Cysteine/genetics, Protein Conformation, Stereochemistry, Movement, Dimer, Bacterial Toxins, Mutant, Aerolysin, Plasma protein binding, Biology, Crystallography, X-Ray, Biochemistry, Oligomer, Fluorescence, Anilino Naphthalenesulfonates, Ion Channels, chemistry.chemical_compound, Protein structure, Models, Ion Channels/*chemistry/genetics/metabolism, Site-Directed, Cysteine, Tryptophan/chemistry, Fluorescent Dyes, chemistry.chemical_classification, Crystallography, Spectrometry, Tryptophan, Wild type, Molecular, Amino acid, Spectrometry, Fluorescence, chemistry, Mutagenesis, ddc:540, X-Ray, Mutagenesis, Site-Directed, Biological Assay, Aeromonas, Aeromonas/metabolism, Bacterial Toxins/*chemistry/genetics/metabolism, Protein Binding
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16
المؤلفون: Susanne C. Feil, Michael W. Parker, Terry W. Spithill, Matthew C.J. Wilce, Jennifer L. Sexton, Jamie Rossjohn
المصدر: Journal of Molecular Biology. 273:857-872
مصطلحات موضوعية: biology, Fasciola, Stereochemistry, Schistosoma japonicum, biology.organism_classification, Epitope, Glutathione S-transferase, Biochemistry, Structural Biology, biology.protein, Fasciola hepatica, Transferase, Molecular replacement, Binding site, Molecular Biology
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17
المؤلفون: Colin M. House, Richard G.H. Cotton, Tony Tiganis, Bruce E. Kemp, Michael W. Parker, Ian G. Jennings, Susanne C. Feil, Belinda J. Michell, Bostjan Kobe
المصدر: Protein Science. 6:1352-1357
مصطلحات موضوعية: chemistry.chemical_classification, Phenylalanine hydroxylase, biology, Tyrosine hydroxylase, Phenylketonurias, Stereochemistry, Biochemistry, Enzyme activator, Enzyme, Protein structure, chemistry, biology.protein, Protein phosphorylation, Protein quaternary structure, Molecular Biology
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18
المؤلفون: Susanne C. Feil, Michael W. Parker, William J. McKinstry, Jamie Rossjohn, Rodney K. Tweten
المصدر: Cell. 89:685-692
مصطلحات موضوعية: Models, Molecular, Protein Folding, MACPF, Biochemistry, Genetics and Molecular Biology(all), Cytotoxins, Cell Membrane, Cholesterol binding, Membranes, Artificial, Biology, Cholesterol-dependent cytolysin, General Biochemistry, Genetics and Molecular Biology, Cell biology, Cell membrane, Cholesterol, medicine.anatomical_structure, Membrane, medicine, Membrane channel, Protein folding, Sulfhydryl Compounds, Cytolysin, Protein Binding
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19
المؤلفون: Klaudiusz R. Weiss, Guy M. Benian, Bruce E. Kemp, Michael W. Parker, Bostjan Kobe, Susanne C. Feil, Jörg Heierhorst
المصدر: The EMBO Journal. 15:6810-6821
مصطلحات موضوعية: General Immunology and Microbiology, biology, Calmodulin, Kinase, General Neuroscience, Immunoglobulin domain, General Biochemistry, Genetics and Molecular Biology, Protein structure, Protein kinase domain, Biochemistry, Myosin binding, biology.protein, Biophysics, Titin, Protein kinase A, Molecular Biology
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20
المؤلفون: Bostjan Kobe, Guy M. Benian, Michael W. Parker, Klaudiusz R. Weiss, Bruce E. Kemp, Susanne C. Feil, Jörg Heierhorst
المصدر: Nature. 380:636-639
مصطلحات موضوعية: Models, Molecular, Calmodulin, Protein Conformation, Molecular Sequence Data, Muscle Proteins, Biology, Crystallography, X-Ray, Ca2+/calmodulin-dependent protein kinase, Aplysia, Animals, Humans, Connectin, Protein phosphorylation, ASK1, Amino Acid Sequence, c-Raf, Caenorhabditis elegans Proteins, Protein kinase A, Protein Kinase Inhibitors, Binding Sites, Multidisciplinary, Kinase, Binding protein, S100 Proteins, Enzyme Activation, Biochemistry, biology.protein, Calcium, Calmodulin-Binding Proteins, Protein Kinases