المؤلفون: Susan M. Clardy, Alex Uttard, Bingfan Du, Kalli C. Catcott, Kelly L. Lancaster, Elizabeth Ditty, Jack Sadowsky, Jeffrey Zurita, Naniye Malli, LiuLiang Qin, Stephen P. Bradley, Kenneth Avocetien, Tyler Carter, Dokyong Kim, Mark Nazzaro, Ling Xu, Thomas H. Pillow, Neelie T. Zacharias, Gail D. Lewis, Rebecca K. Rowntree, Radha Iyengar, David H. Lee, Marc Damelin, Dorin Toader, Timothy B. Lowinger

مصطلحات موضوعية: Cancer, Therapeutic Research and Development, Methods and Technology, Biological Agents & Therapies, Antibody-drug conjugates, Pharmacology, Pharmacokinetics and pharmacodynamics, Protein Technologies

Relation: https://figshare.com/articles/journal_contribution/Table_S4_from_Site-Specific_Dolasynthen_Antibody_Drug_Conjugates_Exhibit_Consistent_Pharmacokinetic_Profiles_across_a_Wide_Range_of_Drug-to-Antibody_Ratios/24935455

الاتاحة: https://doi.org/10.1158/1535-7163.24935455.v1
https://figshare.com/articles/journal_contribution/Table_S4_from_Site-Specific_Dolasynthen_Antibody_Drug_Conjugates_Exhibit_Consistent_Pharmacokinetic_Profiles_across_a_Wide_Range_of_Drug-to-Antibody_Ratios/24935455

المؤلفون: Susan M. Clardy, Alex Uttard, Bingfan Du, Kalli C. Catcott, Kelly L. Lancaster, Elizabeth Ditty, Jack Sadowsky, Jeffrey Zurita, Naniye Malli, LiuLiang Qin, Stephen P. Bradley, Kenneth Avocetien, Tyler Carter, Dokyong Kim, Mark Nazzaro, Ling Xu, Thomas H. Pillow, Neelie T. Zacharias, Gail D. Lewis, Rebecca K. Rowntree, Radha Iyengar, David H. Lee, Marc Damelin, Dorin Toader, Timothy B. Lowinger

مصطلحات موضوعية: Cancer, Therapeutic Research and Development, Methods and Technology, Biological Agents & Therapies, Antibody-drug conjugates, Pharmacology, Pharmacokinetics and pharmacodynamics, Protein Technologies

Relation: https://figshare.com/articles/journal_contribution/Figure_S4_from_Site-Specific_Dolasynthen_Antibody_Drug_Conjugates_Exhibit_Consistent_Pharmacokinetic_Profiles_across_a_Wide_Range_of_Drug-to-Antibody_Ratios/24935473

الاتاحة: https://doi.org/10.1158/1535-7163.24935473.v1
https://figshare.com/articles/journal_contribution/Figure_S4_from_Site-Specific_Dolasynthen_Antibody_Drug_Conjugates_Exhibit_Consistent_Pharmacokinetic_Profiles_across_a_Wide_Range_of_Drug-to-Antibody_Ratios/24935473

المؤلفون: Susan M. Clardy, Alex Uttard, Bingfan Du, Kalli C. Catcott, Kelly L. Lancaster, Elizabeth Ditty, Jack Sadowsky, Jeffrey Zurita, Naniye Malli, LiuLiang Qin, Stephen P. Bradley, Kenneth Avocetien, Tyler Carter, Dokyong Kim, Mark Nazzaro, Ling Xu, Thomas H. Pillow, Neelie T. Zacharias, Gail D. Lewis, Rebecca K. Rowntree, Radha Iyengar, David H. Lee, Marc Damelin, Dorin Toader, Timothy B. Lowinger

مصطلحات موضوعية: Cancer, Therapeutic Research and Development, Methods and Technology, Biological Agents & Therapies, Antibody-drug conjugates, Pharmacology, Pharmacokinetics and pharmacodynamics, Protein Technologies

Relation: https://figshare.com/articles/journal_contribution/Supplemental_Data_File_1_from_Site-Specific_Dolasynthen_Antibody_Drug_Conjugates_Exhibit_Consistent_Pharmacokinetic_Profiles_across_a_Wide_Range_of_Drug-to-Antibody_Ratios/24935467

الاتاحة: https://doi.org/10.1158/1535-7163.24935467.v1
https://figshare.com/articles/journal_contribution/Supplemental_Data_File_1_from_Site-Specific_Dolasynthen_Antibody_Drug_Conjugates_Exhibit_Consistent_Pharmacokinetic_Profiles_across_a_Wide_Range_of_Drug-to-Antibody_Ratios/24935467

المؤلفون: Susan M. Clardy (10636361), David H. Lee (4426972), Peter Schuck (27088)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Inorganic Chemistry, Hematology, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, conjugate, Multisignal Sedimentation Velocity ., multisignal sedimentation velocity, polymer-to-protein ratio

Relation: https://figshare.com/articles/journal_contribution/Determining_the_Stoichiometry_of_a_Protein_Polymer_Conjugate_Using_Multisignal_Sedimentation_Velocity_Analytical_Ultracentrifugation/14410328

الاتاحة: https://doi.org/10.1021/acs.bioconjchem.1c00095.s001

المؤلفون: Timothy B. Lowinger, Donald A. Bergstrom, Peter U. Park, Qingxiu Zhang, Ling Xu, Marina Protopopova, Laura L. Poling, Michael J. DeVit, Dennis McGillicuddy, Venu R. Gurijala, Alex J. Johnson, Charlie Bu, Elena Ter-Ovanesyan, Dmitry R. Gumerov, LiuLiang Qin, Alex Uttard, Cheri A. Stevenson, Patrick R. Conlon, Susan M. Clardy, Joshua D. Thomas, Mao Yin, Natalya D. Bodyak, Aleksandr V. Yurkovetskiy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650945d96b4cb4ca36cc61fe8daa399d
https://doi.org/10.1158/1535-7163.22522479

المؤلفون: Timothy B. Lowinger, Donald A. Bergstrom, Peter U. Park, Qingxiu Zhang, Ling Xu, Marina Protopopova, Laura L. Poling, Michael J. DeVit, Dennis McGillicuddy, Venu R. Gurijala, Alex J. Johnson, Charlie Bu, Elena Ter-Ovanesyan, Dmitry R. Gumerov, LiuLiang Qin, Alex Uttard, Cheri A. Stevenson, Patrick R. Conlon, Susan M. Clardy, Joshua D. Thomas, Mao Yin, Natalya D. Bodyak, Aleksandr V. Yurkovetskiy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951b8c25dbbe73e1c85ae90ec75bc178
https://doi.org/10.1158/1535-7163.c.6543396

المؤلفون: Wenxian Fu, Julia Farache, Susan M Clardy, Kimie Hattori, Palwinder Mander, Kevin Lee, Inmaculada Rioja, Ralph Weissleder, Rab K Prinjha, Christophe Benoist, Diane Mathis

المصدر: eLife, Vol 3 (2014)

مصطلحات موضوعية: autoimmune diabetes, bromodomain inhibitor, NF-KB, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/04631; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/2c8f50f554684e36ac5b057e7ed40c84

المؤلفون: Peter Schuck, David H. Lee, Susan M. Clardy

المصدر: Bioconjugate chemistry. 32(5)

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Polymers, Organic Chemistry, Biomedical Engineering, Pharmaceutical Science, A protein, Proteins, Bioengineering, 02 engineering and technology, Polymer, Sedimentation, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Characterization (materials science), Analytical Ultracentrifugation, 0210 nano-technology, Biological system, Ultracentrifugation, Stoichiometry, Biotechnology, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9627ce0c34ebffff7299b881094d3b3
https://pubmed.ncbi.nlm.nih.gov/33848127

المؤلفون: Susan M. Clardy, Eugene W. Kelleher, Raghida A. Bukhalid, LiuLiang Qin, Rebecca Mosher, Timothy B. Lowinger, Dorin Toader, Joshua D. Thomas, Kalli C. Catcott, Pamela Shaw, Chen-Ni Chin, Kenneth Avocetien, Marc Damelin, Brian D. Jones, Kelly Slocum, Jeremy R. Duvall, Travis Monnell, Keith W. Bentley, Naniye Malli Cetinbas, Winnie Lee

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

مصطلحات موضوعية: 0301 basic medicine, Agonist, Innate immune system, biology, medicine.drug_class, business.industry, Monocyte, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, eye diseases, body regions, 03 medical and health sciences, Sting, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Immune system, 030220 oncology & carcinogenesis, Cancer cell, medicine, biology.protein, Cancer research, Antibody, Receptor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81256e4265903f4d896728e7189e96e3
https://doaj.org/article/b5031bee1db5458fb014131f0b1a8d8c

المؤلفون: Venu R. Gurijala, Joshua D. Thomas, Cheri A. Stevenson, Dmitry R. Gumerov, Dennis McGillicuddy, Aleksandr V. Yurkovetskiy, LiuLiang Qin, Laura L. Poling, Alex Johnson, Timothy B. Lowinger, Donald A. Bergstrom, Ling Xu, Peter U. Park, Marina Protopopova, Elena Ter-Ovanesyan, Natalya D. Bodyak, Patrick R. Conlon, Michael J. DeVit, Alex Uttard, Charlie Bu, Qingxiu Zhang, Mao Yin, Susan M. Clardy

المصدر: Molecular cancer therapeutics. 20(5)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antibody-drug conjugate, Immunoconjugates, Polymers, Cell, Mice, SCID, 03 medical and health sciences, Mice, 0302 clinical medicine, Pharmacokinetics, In vivo, Cell Line, Tumor, medicine, Bystander effect, Animals, Humans, Cell Proliferation, Chemistry, In vitro, body regions, 030104 developmental biology, medicine.anatomical_structure, Cell killing, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, Oligopeptides, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edd41dba66c5c6d946fa5f9db888342
https://pubmed.ncbi.nlm.nih.gov/33722857

المؤلفون: Naniye Malli Cetinbas, Pamela Shaw, Dorin Toader, Keith W. Bentley, Eoin Kelleher, Susan M. Clardy, Marc Damelin, Jeremy R. Duvall, Rebecca Mosher, Winnie Lee, Brian D. Jones, Kenneth Avocetien, Travis Monnell, Kelly Slocum, Raghida A. Bukhalid, Joshua D. Thomas, Timothy B. Lowinger, Kalli C. Catcott

المصدر: Cancer Research. 81:1773-1773

مصطلحات موضوعية: Antitumor activity, Cancer Research, Sting, Oncology, Chemistry, Cancer research, Agonism, Tumor cells, eye diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9908c2e672c4e4b79e304926c0b68f5d
https://doi.org/10.1158/1538-7445.am2021-1773

المؤلفون: Kelly Slocum, Rebecca Mosher, Jeffrey Zurita, Kenneth Avocetien, Joshua D. Thomas, Timothy B. Lowinger, Kalli C. Catcott, Susan M. Clardy, Marc Damelin, Jeremy R. Duvall, Marina Protopopova, Naniye Malli Cetinbas, Scott D. Collins, Ling Xu, Keith W. Bentley, Brian D. Jones, Elena Ter-Ovanesyan, Eugene W. Kelleher, Timothy Eitas, Raghida A. Bukhalid, Dorin Toader, Liping Yang, Travis Monnell, Elizabeth Ditty, LiuLiang Qin, Winnie Lee, Pamela Shaw, Phonphimon Wongthida, Stephen Bradley

المصدر: Cancer Research. 81:1738-1738

مصطلحات موضوعية: Agonist, Antitumor activity, Cancer Research, Antibody-drug conjugate, Sting, Immune system, Oncology, medicine.drug_class, business.industry, medicine, Pharmacology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6dd4080a98b5a36ec4e0e10f0f535b90
https://doi.org/10.1158/1538-7445.am2021-1738

المؤلفون: Scott D. Collins, Kelly Slocum, Jason K. Wang, Dorin Toader, Ling Xu, Elizabeth Ditty, Chen-Ni Chin, Anouk Dirksen, Marc Damelin, Steven Vonderfecht, Rebecca Mosher, Dokyong Kim, Jeffrey Zurita, Susan M. Clardy, Kenneth Avocetien, Ronald Eydelloth, Timothy B. Lowinger, LiuLiang Qin, Bingfan Du, Steven Bradley, Shawn P. Fessler, Phonphimon Wongthida, Alex Uttard, Elena Ter-Ovanesyen

المصدر: Cancer Research. 81:907-907

مصطلحات موضوعية: Cancer Research, Antibody-drug conjugate, biology, business.industry, T cell, Cancer, medicine.disease, Tumor antigen, Breast cancer, medicine.anatomical_structure, Oncology, In vivo, Cancer cell, medicine, Cancer research, biology.protein, Antibody, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8d2807e2ea7c8be1c11fb15f3c7dc8f0
https://doi.org/10.1158/1538-7445.am2021-907

المؤلفون: Claudio Vinegoni, Ralph Weissleder, Susan M. Clardy, Edmund J. Keliher, Rainer H. Kohler, Yoshiko Iwamoto

المصدر: TECHNOLOGY. :130-134

مصطلحات موضوعية: 0301 basic medicine, 030209 endocrinology & metabolism, Biology, First generation, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Biochemistry, Two-photon excitation microscopy, In vivo, Pancreatic beta Cells, Biophysics, Beta cell, Preclinical imaging, Multiphoton imaging, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::df5680ca360510936c6970fa1155c5db
https://doi.org/10.1142/s2339547816200028

المؤلفون: Kalli C. Catcott, Kelly Slocum, Marina Protopopova, Liping Yang, Joshua D. Thomas, Mark Nazzaro, Scott D. Collins, Chen-Ni Chin, Dorin Toader, LiuLiang Qin, Rebecca Mosher, Ling Xu, Jeffrey Zurita, Kenneth Avocetien, Tyler Carter, Raghida A. Bukhalid, Elena Ter-Ovanesyan, Keith W. Bentley, Marc Damelin, Jeremy R. Duvall, Naniye Malli Cetinbas, Timothy Eitas, Brian D. Jones, Stephen Bradley, Pamela Shaw, Susan M. Clardy, Timothy B. Lowinger, Eugene W. Kelleher

المصدر: Cancer Research. 80:6706-6706

مصطلحات موضوعية: Agonist, Cancer Research, medicine.drug_class, business.industry, Pharmacology, eye diseases, Proinflammatory cytokine, Sting, Immune system, Oncology, Antigen, In vivo, Interferon, Systemic administration, medicine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb8874b5832868b1dcd0fa515563fcc7
https://doi.org/10.1158/1538-7445.am2020-6706

المؤلفون: Wolfgang Weber, Thomas Reiner, Christian Brand, Yachao Zhang, Susan M. Clardy, Jason S. Lewis, Sean Carlin, Dalya Abdel-Atti, Edmund J. Keliher

المصدر: Bioconjugate Chemistry

مصطلحات موضوعية: Fluorescence-lifetime imaging microscopy, Pharmaceutical Science, Fluorescent Antibody Technique, Multimodal Imaging, 030218 nuclear medicine & medical imaging, Mice, 0302 clinical medicine, Receptors, Glucagon, Cells, Cultured, medicine.diagnostic_test, Chemistry, Optical Imaging, Adenoma, Islet Cell, Fluorescence, Imaging agent, 3. Good health, medicine.anatomical_structure, Positron emission tomography, Cell Tracking, 030220 oncology & carcinogenesis, Female, Pancreas, Preclinical imaging, Biotechnology, Molecular Sequence Data, Biomedical Engineering, Mice, Nude, Bioengineering, Article, Glucagon-Like Peptide-1 Receptor, 03 medical and health sciences, In vivo, medicine, Animals, Humans, Hypoglycemic Agents, Amino Acid Sequence, Pharmacology, business.industry, Venoms, Organic Chemistry, Xenograft Model Antitumor Assays, Copper Radioisotopes, Positron-Emission Tomography, Exenatide, Radiopharmaceuticals, Nuclear medicine, business, Peptides, Ex vivo, Biomedical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aaeaa66877491bf57083b8e075e26b7
http://europepmc.org/articles/PMC4215873

المؤلفون: David H. Lee, Marc Damelin, Shawn P. Fesler, Cheri A. Stevenson, Ling Xu, Kalli C. Cattcott, Scott D. Collins, Alex Uttard, Mariya Kozytska, Barrett J. Nehilla, Patrick R. Conlon, Timothy B. Lowinger, LiuLiang Qin, Winnie Lee, Dorin Toader, Anouk Dirksen, Susan M. Clardy, Chen-Ni Chin, Jian Xu

المصدر: Cancer Research. 79:2687-2687

مصطلحات موضوعية: Cancer Research, Antibody-drug conjugate, Bioconjugation, Chemistry, Stereochemistry, medicine.drug_class, Monoclonal antibody, In vitro, chemistry.chemical_compound, Oncology, Tolerability, In vivo, Amide, medicine, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::870da3afc665ace2484d28c1f441cacd
https://doi.org/10.1158/1538-7445.am2019-2687

المؤلفون: Andres Fernandez del Castillo, Rui Wang, Chen Han Huang, Katherine S. Yang, Soldano Ferrone, Ilaria Pergolini, Robert Yang, Hakho Lee, Carlos Fernandez-del Castillo, Hyungsoon Im, Ralph Weissleder, Seonki Hong, Craig Pille, Susan M. Clardy, Cesar M. Castro

المصدر: Science translational medicine. 9(391)

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, medicine.medical_specialty, Pancreatic ductal adenocarcinoma, Pancreatic malignancy, CA-19-9 Antigen, Biology, Gastroenterology, Extracellular vesicles, 03 medical and health sciences, 0302 clinical medicine, Text mining, Pancreatic cancer, Internal medicine, Carcinoma, medicine, Biomarkers, Tumor, Humans, Prospective Studies, Prospective cohort study, business.industry, General Medicine, medicine.disease, Confidence interval, Pancreatic Neoplasms, 030104 developmental biology, Editorial, 030220 oncology & carcinogenesis, Female, business, Carcinoma, Pancreatic Ductal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62591100f60238fae05fca7df6823da7
https://pubmed.ncbi.nlm.nih.gov/29299462

المؤلفون: Mao Yin, Timothy B. Lowinger, David H. Lee, Alex Yurkovetskiy, Elena Ter-Ovanesyan, Marina Protopopova, Dmitry R. Gumerov, Natalya D. Bodyak, Donald A. Bergstrom, Susan M. Clardy, Alex Johnson, Marc Damelin, Qingxiu Zhang, Ling Xu, Charlie Bu

المصدر: Cancer Research. 78:754-754

مصطلحات موضوعية: Cancer Research, Biodistribution, Chemistry, Cell, In vitro, medicine.anatomical_structure, Oncology, Antigen, In vivo, Bystander effect, medicine, Cancer research, Cytotoxic T cell, Cytotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ee0dd6fddaccfb922909153b7da0b32
https://doi.org/10.1158/1538-7445.am2018-754

المؤلفون: Diane Mathis, James F. Mohan, Christophe Benoist, Edmund J. Keliher, Ralph Weissleder, Claudio Vinegoni, Yoshiko Iwamoto, Susan M. Clardy

المصدر: Scientific Reports

مصطلحات موضوعية: Boron Compounds, medicine.medical_treatment, Cell Separation, Biology, Glucagon, Article, Diabetes Mellitus, Experimental, Flow cytometry, Mice, Inbred NOD, Insulin-Secreting Cells, medicine, Animals, Insulin, Receptor, NOD mice, Multidisciplinary, medicine.diagnostic_test, Venoms, Gene Expression Profiling, Molecular biology, Mice, Inbred C57BL, Gene expression profiling, Immunology, Exenatide, Female, Peptides, Somatostatin, Immunostaining, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9b62f3c8fc916a966ab0ed26b34eec
https://doi.org/10.1038/srep13681