المؤلفون: Jonathan A Lee, Paul Shinn, Susan Jaken, Sarah Oliver, Francis S Willard, Steven Heidler, Robert B Peery, Jennifer Oler, Shaoyou Chu, Noel Southall, Thomas S Dexheimer, Jeffrey Smallwood, Ruili Huang, Rajarshi Guha, Ajit Jadhav, Karen Cox, Christopher P Austin, Anton Simeonov, G Sitta Sittampalam, Saba Husain, Natalie Franklin, David J Wild, Jeremy J Yang, Jeffrey J Sutherland, Craig J Thomas

المصدر: PLoS ONE, Vol 10, Iss 7, p e0130796 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4503722?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/1946423edacf41cd981806581d41073c

المؤلفون: Owen A. O'Connor, Susan Jaken, Andrew S. Wasmuth, Wei-Yann Tsai, Christine McIntosh, Xavier O. Jirau Serrano, Richard Rodriguez, Mark Lipstein, Changchun Deng

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1480b3b7892f13ffe4be8f319677773b
https://doi.org/10.1158/1078-0432.22456092.v1

المؤلفون: Owen A. O'Connor, Susan Jaken, Andrew S. Wasmuth, Wei-Yann Tsai, Christine McIntosh, Xavier O. Jirau Serrano, Richard Rodriguez, Mark Lipstein, Changchun Deng

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b39e20bb9f50e025d49af4ff714f0c6
https://doi.org/10.1158/1078-0432.22456101

المؤلفون: Owen A. O'Connor, Susan Jaken, Andrew S. Wasmuth, Wei-Yann Tsai, Christine McIntosh, Xavier O. Jirau Serrano, Richard Rodriguez, Mark Lipstein, Changchun Deng

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d09eb57d9355c4351df523926186c51
https://doi.org/10.1158/1078-0432.c.6523203

المؤلفون: Owen A. O'Connor, Susan Jaken, Andrew S. Wasmuth, Wei-Yann Tsai, Christine McIntosh, Xavier O. Jirau Serrano, Richard Rodriguez, Mark Lipstein, Changchun Deng

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351b72c3ec04c966976429a7d46ba131
https://doi.org/10.1158/1078-0432.22456095.v1

المؤلفون: Lynn Fowler, Jeffrey Everitt, James L Stevens, Susan Jaken

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://cgd.aacrjournals.org/cgi/reprint/9/5/405.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.4545; http://cgd.aacrjournals.org/cgi/reprint/9/5/405.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.4545
http://cgd.aacrjournals.org/cgi/reprint/9/5/405.pdf

المؤلفون: Hua Fung, Timothy R. Quinlan, Yvonne M. W. Janssen, Cancer Res, Contact The Aacr Publications, Cynthia R. Timblin, Joanne P. Marsh, Nicholas H. Heintz, Douglas J. Taatjes, Pamela Vacek, Susan Jaken, Brooke T. Mossman

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://cancerres.aacrjournals.org/content/57/15/3101.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.7935; http://cancerres.aacrjournals.org/content/57/15/3101.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.7935
http://cancerres.aacrjournals.org/content/57/15/3101.full.pdf

المؤلفون: Youyan Zhang, Eliza Vakana, Michele Dowless, Susan Jaken, Louis Stancato, Wayne Blosser, Nicholas Simpson, Lysiane Huber, Sheng-Bin Peng, Susan E. Pratt, Jennifer R. Stephens, Jason Manro, Xiu-Juan Yuan

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Time Factors, Colorectal cancer, Cell, Apoptosis, medicine.disease_cause, Extracellular Signal-Regulated MAP Kinases, Melanoma, Tumor Burden, medicine.anatomical_structure, Phenotype, Oncology, Female, RNA Interference, KRAS, Colorectal Neoplasms, HT29 Cells, Research Paper, Proto-Oncogene Proteins B-raf, congenital, hereditary, and neonatal diseases and abnormalities, colorectal cancer, Antineoplastic Agents, Transfection, Proto-Oncogene Proteins A-raf, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Rats, Nude, medicine, Animals, Humans, Genetic Predisposition to Disease, Kinase activity, Protein kinase B, neoplasms, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, business.industry, Phenylurea Compounds, RAF, medicine.disease, HCT116 Cells, G1 Phase Cell Cycle Checkpoints, digestive system diseases, signaling pathways, Proto-Oncogene Proteins c-raf, 030104 developmental biology, Pyrimidines, Immunology, Mutation, Cancer research, xenograft models, ARAF, business, Proto-Oncogene Proteins c-akt, RAS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9dee6fe3b13bc87210e961795693e6c
http://europepmc.org/articles/PMC5354729

المؤلفون: Ian Liao, Katrina Ramsay, Susan Jaken

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://cgd.aacrjournals.org/cgi/reprint/5/11/1185.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.1302; http://cgd.aacrjournals.org/cgi/reprint/5/11/1185.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.1302
http://cgd.aacrjournals.org/cgi/reprint/5/11/1185.pdf

المؤلفون: Francis S. Willard, Steven A. Heidler, Jonathan A. Lee, G. Sitta Sittampalam, Robert B. Peery, Ajit Jadhav, Saba Husain, Sarah E. Oliver, Jeremy J. Yang, Noel Southall, Shaoyou Chu, Thomas S. Dexheimer, David J. Wild, Paul Shinn, Christopher P. Austin, Craig J. Thomas, Natalie Franklin, Jennifer Oler, Anton Simeonov, Jeffrey K. Smallwood, Susan Jaken, Ruili Huang, Rajarshi Guha, Karen Cox, Jeffrey J. Sutherland

المصدر: PLoS ONE, Vol 10, Iss 7, p e0130796 (2015)
PLoS ONE

مصطلحات موضوعية: Sorafenib, Drug Evaluation, Preclinical, lcsh:Medicine, Computational biology, Pharmacology, Pazopanib, Small Molecule Libraries, Inhibitory Concentration 50, Cell Line, Tumor, High-Throughput Screening Assays, medicine, Humans, lcsh:Science, Drug Approval, Multidisciplinary, Drug discovery, business.industry, lcsh:R, Drug Repositioning, Axitinib, Drug repositioning, Phenotype, lcsh:Q, Translational science, business, PubChem, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bef9afbfef400dbca451e7fa2adced8
http://europepmc.org/articles/PMC4503722?pdf=render

المؤلفون: Karen L. Huss, Mclean Johnathan Alexander, Zhao Gaiying, Robert S. Flack, Andrew J. Dropsey, Xueqian Gong, Michael John Rodriguez, Sajan Joseph, Matthew Whitesell, Lisa Kindler, Jennie L. Walgren, Jason Manro, Ramon V. Tiu, Baohui Zhao, Brian Michael Mathes, Denis J. McCann, Xiu-Juan Yuan, Susan Jaken, Shufen Cai, Bryan D. Anderson, William T. McMillen, Eunice Yuen, Shripad V. Bhagwat, Cortez Guillermo S, Wenjuan Wu

المصدر: Cancer Research. 77:3231-3231

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Kinase, business.industry, Cancer, Pharmacology, medicine.disease, Oncology, In vivo, medicine, Potency, business, Clinical evaluation, IC50, Human cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1824ca165bb8dc39a5634940817bcacd
https://doi.org/10.1158/1538-7445.am2017-3231

المؤلفون: Ramon V. Tiu, Brian Michael Mathes, Xueqian Gong, Bryan D. Anderson, Michael John Rodriguez, William T. McMillen, Shufen Cai, Andrew J. Dropsey, Eunice Yuen, Wenjuan Wu, Lisa Kindler, Robert S. Flack, Sajan Joseph, Susan Jaken, Karen L. Huss, Jennie L. Walgren, Matthew Whitesell, Baohui Zhao, Sheng-Bin Peng, Denis J. McCann, Xiu-Juan Yuan, Shripad V. Bhagwat, Jianping Huang, Jason Manro

المصدر: Cancer Research. 77:4973-4973

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, MAPK/ERK pathway, Cancer Research, business.industry, Cell growth, Kinase, Melanoma, medicine.disease, medicine.disease_cause, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, chemistry, 030220 oncology & carcinogenesis, Pancreatic cancer, Cancer research, Medicine, KRAS, business, Abemaciclib

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e0ccea014ccd0304cc1f9b55feba9468
https://doi.org/10.1158/1538-7445.am2017-4973

المؤلفون: Wei-Yann Tsai, Changchun Deng, Richard Rodriguez, Xavier O. Jirau Serrano, Susan Jaken, Mark Lipstein, Owen A. O'Connor, Andrew S. Wasmuth, Christine McIntosh

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 21(1)

مصطلحات موضوعية: Cancer Research, Lymphoma, Apoptosis, IκB kinase, Thiophenes, Pharmacology, Biology, Romidepsin, chemistry.chemical_compound, Mice, Cell Line, Tumor, medicine, Animals, Humans, Electrophoretic mobility shift assay, NF-kappa B, Drug Synergism, medicine.disease, Flow Cytometry, I-kappa B Kinase, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, Pyrimidines, Oncology, chemistry, Mechanism of action, Histone deacetylase, Growth inhibition, medicine.symptom, medicine.drug, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e73d689c5b4448e232b383ac80bff76
https://pubmed.ncbi.nlm.nih.gov/25355930

المؤلفون: Peter J. Parker, Susan Jaken

المصدر: BioEssays. 22:245-254

مصطلحات موضوعية: PTK2B, Cyclin-dependent kinase complex, Protein kinase C binding, c-Raf, Biology, Protein kinase A, General Biochemistry, Genetics and Molecular Biology, Protein kinase C, SH3 domain, Cell biology, MAP2K7

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0407ddb0ceb4bebcdef231535baa4c08
https://doi.org/10.1002/(sici)1521-1878(200003)22:3<245::aid-bies6>3.0.co;2-x

المؤلفون: Xuequn Xu, Susan Jaken, Betty Mousseau, Theresa Klauck

المصدر: Journal of Biological Chemistry. 271:19781-19788

مصطلحات موضوعية: Male, Diacylglycerol Kinase, Molecular Sequence Data, Cell, Gene Expression, Spodoptera, Biochemistry, Homology (biology), Cricetinae, Complementary DNA, medicine, Animals, Humans, Tissue Distribution, Amino Acid Sequence, RNA, Messenger, Ribonuclease, Cloning, Molecular, Glucocorticoids, Molecular Biology, DNA Primers, Diacylglycerol kinase, Base Sequence, Mesocricetus, Sequence Homology, Amino Acid, biology, Cell Biology, Recombinant Proteins, Cell Compartmentation, Rats, Pleckstrin homology domain, Phosphotransferases (Alcohol Group Acceptor), medicine.anatomical_structure, Second messenger system, biology.protein, Sequence Alignment, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febb2b7b56d76bec7270609314ae18a5
https://doi.org/10.1074/jbc.271.33.19781

المؤلفون: Susan C. Kiley, Yin Li, Steven Duddy, Christine Chapline, Betty Mousseau, Katrina Ramsay, Susan Jaken

المصدر: Journal of Biological Chemistry. 271:6417-6422

مصطلحات موضوعية: Open reading frame, Immunoprecipitation, Kinase, Binding protein, Clone (cell biology), Protein kinase C binding, Cell Biology, AKAP12, Biology, Molecular Biology, Biochemistry, Molecular biology, Protein kinase C

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a40aba3c750e21a6f4da97643d34dd34
https://doi.org/10.1074/jbc.271.11.6417

المؤلفون: Susan Jaken, Richard D. H. Whelan, Susan C. Kiley, Peter J. Parker

المصدر: Biochemical Society Transactions. 23:601-605

مصطلحات موضوعية: MAP kinase kinase kinase, Chemistry, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Proteins, Mitogen-activated protein kinase kinase, Biochemistry, Isozyme, Cell Compartmentation, Cell Line, Rats, Isoenzymes, Phenotype, P70S6 kinase, Animals, Humans, Cyclin-dependent kinase 9, ASK1, Myristoylated Alanine-Rich C Kinase Substrate, Cytoskeleton, Protein Kinase C, Intracellular, Protein kinase C, Subcellular Fractions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40683ce26011529ff3e17ed8cc10876
https://doi.org/10.1042/bst0230601

المؤلفون: Peter J. Parker, I. Bernard Weinstein, Marius Ueffing, Christoph Borner, Susan Jaken

المصدر: Journal of Biological Chemistry. 270:78-86

مصطلحات موضوعية: Gene isoform, medicine.medical_specialty, Cell, Cell Biology, Biology, medicine.disease_cause, Biochemistry, Epidermal growth factor receptor binding, Cell biology, medicine.anatomical_structure, Endocrinology, Internal medicine, Collagenase, medicine, Carcinogenesis, Molecular Biology, Protein kinase C, medicine.drug, Regulator gene, Diacylglycerol kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::524a5cbe76e52cd0db6e6ede0a20ed05
https://doi.org/10.1074/jbc.270.1.78

المؤلفون: Susan C. Kiley, Susan Jaken

المصدر: Trends in Cell Biology. 4:223-227

مصطلحات موضوعية: Biochemistry, Cell Biology, Biology, Protein kinase C

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d39b7255181759895e0272e855541b
https://doi.org/10.1016/0962-8924(94)90146-5

المؤلفون: Katrina Ramsay, Christine Chapline, Theresa Klauck, Susan Jaken

المصدر: Journal of Biological Chemistry. 268:6858-6861

مصطلحات موضوعية: Molecular Sequence Data, Biology, Molecular cloning, Biochemistry, DNA-binding protein, Substrate Specificity, Complementary DNA, Animals, Amino Acid Sequence, Cloning, Molecular, MARCKS, Myristoylated Alanine-Rich C Kinase Substrate, Molecular Biology, Protein Kinase C, Protein kinase C, Sequence Homology, Amino Acid, cDNA library, Binding protein, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Proteins, Cell Biology, Rats, Membrane protein, Electrophoresis, Polyacrylamide Gel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b5e0d88a07a27557a66445b2f3d835
https://doi.org/10.1016/s0021-9258(18)53116-1