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1Academic JournalRegulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.
المؤلفون: Alessio Iannetti, Adeline C Ledoux, Susan J Tudhope, Hélène Sellier, Bo Zhao, Sophia Mowla, Adam Moore, Holger Hummerich, Benjamin E Gewurz, Simon J Cockell, Parmjit S Jat, Elaine Willmore, Neil D Perkins
المصدر: PLoS Genetics, Vol 10, Iss 9, p e1004642 (2014)
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Evan A Mulligan, Susan J Tudhope, Jill E Hunter, Arabella E G Clift, Sarah L Elliott, Geoffrey P Summerfield, Jonathan Wallis, Christopher Pepper, Barabara Durkacz, Stephany Veuger, Elaine Willmore
مصطلحات موضوعية: Biomedical and clinical sciences, Cardiovascular medicine and haematology, Oncology and carcinogenesis, CLL, NF-κB, RelB, 32 Biomedical and Clinical Sciences, 3201 Cardiovascular Medicine and Haematology, 3211 Oncology and Carcinogenesis, Cancer, Rare Diseases, Hematology, Clinical Research, Lymphoma, 5.1 Pharmaceuticals, 2 Aetiology, 5 Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, 1112 Oncology and Carcinogenesis
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3Academic Journal
المؤلفون: Evan A. Mulligan, Susan J. Tudhope, Jill E. Hunter, Arabella E. G. Clift, Sarah L. Elliott, Geoffrey P. Summerfield, Jonathan Wallis, Chris J. Pepper, Barabara Durkacz, Stephany Veuger, Elaine Willmore
المصدر: Cancers, Vol 15, Iss 4736, p 4736 (2023)
مصطلحات موضوعية: NF-κB, CLL, RelB, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Relation: https://www.mdpi.com/2072-6694/15/19/4736; https://doaj.org/toc/2072-6694; https://doaj.org/article/4590e41b6dda45eb8f214169c89e2e40
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4
المؤلفون: Lan Z. Wang, Miller Duncan Charles, Bernard T. Golding, Ian Hickson, Martin E.M. Noble, Celine Cano, Suzannah J. Harnor, Michael J. Waring, Harry J Shrives, Shaimaa Khalifa, Jane Totobenazara, Stephen J. Hobson, Elaine Willmore, Hannah L Stewart, Mathew P. Martin, Susan J. Tudhope, Huw D. Thomas, Islam Al-Khawaldeh, Claire E. Jennings, João V de Souza, Max J. Temple, Jane A. Endicott, Cinzia Bordoni, Honorine Lebraud, Agnieszka K. Bronowska, Ian R. Hardcastle, Amy B. Heptinstall, Stephen R. Wedge, Christine Basmadjian, Gregory G Aldred, Julie A. Tucker, Mohammed J Al Yasiri
المصدر: Journal of Medicinal Chemistry. 64:10001-10018
مصطلحات موضوعية: chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Chemistry, Kinase, Active site, Protein Serine-Threonine Kinases, Structure-Activity Relationship, Residue (chemistry), Pyrimidines, Enzyme, Biochemistry, Covalent bond, Alkynes, Drug Discovery, Cancer cell, biology.protein, Humans, Molecular Medicine, Kinome, Cysteine, Protein Kinase Inhibitors
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5
المؤلفون: Fadhel M. Lafta, Laura Woodhouse, Gordon Strathdee, Helen Marr, Scott Marshall, Elaine Willmore, Timothy M. Barrow, Susan J. Tudhope, Kateryna Bilotkach, Nick Bown, Jonathan P. Wallis, Sirintra Nakjang, Gesa Junge
المصدر: British Journal of Cancer
مصطلحات موضوعية: Oncology, Epigenomics, Male, Cancer Research, medicine.medical_specialty, Chronic lymphocytic leukaemia, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Genetics research, Cancer genomics, Medicine, Humans, Epigenetics, Homeodomain Proteins, sub_healthsciences, DNA methylation, business.industry, Epigenome, Leukemia, Lymphocytic, Chronic, B-Cell, Fludarabine, Differentially methylated regions, chemistry, MAFB, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Ibrutinib, Female, Neoplasm Recurrence, Local, Idelalisib, business, sub_biomedicalsciences, medicine.drug, Transcription Factors
وصف الملف: application/pdf
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المؤلفون: Ziad H. Al-Oanzi, Sophia Fountana, Ahmed Alshawi, Loranne Agius, John L. Petrie, Susan J. Tudhope, G.L. Patman, Catherine Arden, Tabassum Moonira, Helen L. Reeves
المصدر: Diabetes, Obesity and Metabolism. 19:1078-1087
مصطلحات موضوعية: 0301 basic medicine, Regulation of gene expression, medicine.medical_specialty, G6PC, Glucokinase, Endocrinology, Diabetes and Metabolism, Fructose, Biology, Metformin, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, chemistry, Internal medicine, Hepatocyte, Internal Medicine, medicine, Psychological repression, Pyruvate kinase, medicine.drug
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المؤلفون: Huw D. Thomas, Celine Cano, Anderson J. Ryan, M. Raymond V. Finlay, Yanyan Jiang, Yan Zhao, Helen L. Reeves, Nicole Phillips, Luiza Madia Lourenco, Catherine E. Willoughby, Gesa Junge, David R. Newell, Joanne M. Munck, Anita Wittner, Lisa Prendergast, Roger J. Griffin, Stephen R. Wedge, Tommy Rennison, Suzanne Kyle, Turner Paul, Elaine Willmore, Susan J. Tudhope, James Pickles
المصدر: The Journal of Clinical Investigation
مصطلحات موضوعية: 0301 basic medicine, Carcinoma, Hepatocellular, DNA damage, medicine.drug_class, DNA repair, medicine.medical_treatment, DNA-Activated Protein Kinase, Therapeutics, 03 medical and health sciences, Mice, 0302 clinical medicine, Therapeutic index, Liver Neoplasms, Experimental, medicine, Animals, Humans, Doxorubicin, Protein Kinase Inhibitors, Chemotherapy, business.industry, General Medicine, medicine.disease, Xenograft Model Antitumor Assays, 3. Good health, Neoplasm Proteins, Radiation therapy, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Toxicity, Cancer research, MCF-7 Cells, business, Liver cancer, Topoisomerase inhibitor, medicine.drug, Research Article
وصف الملف: application/pdf
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8
المؤلفون: Benoit Carbain, E. Anscombe, Jane A. Endicott, Christopher R. Coxon, Mathew P. Martin, Stephen R. Wedge, Christopher Wong, Svitlana Korolchuk, Mangaleswaran Sivaprakasam, Bernard T. Golding, Lisa K. Harlow, Celine Cano, Suzannah J. Harnor, Christopher J. Matheson, Lan Z. Wang, David M. Turner, Martin E.M. Noble, David R. Newell, Ian R. Hardcastle, Roger J. Griffin, Susan J. Tudhope
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: 0301 basic medicine, RM, Stereochemistry, Crystallography, X-Ray, 01 natural sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Non-competitive inhibition, Cyclin-dependent kinase, Drug Discovery, Ribose, Structure–activity relationship, QD, Binding site, Protein Kinase Inhibitors, Cyclin-dependent kinase 1, biology, top_sciences, 010405 organic chemistry, Spectrum Analysis, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Active site, 0104 chemical sciences, 3. Good health, 030104 developmental biology, chemistry, Purines, biology.protein, Molecular Medicine, biological phenomena, cell phenomena, and immunity
وصف الملف: application/pdf
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المؤلفون: Ziad H, Al-Oanzi, Sophia, Fountana, Tabassum, Moonira, Susan J, Tudhope, John L, Petrie, Ahmed, Alshawi, Gillian, Patman, Catherine, Arden, Helen L, Reeves, Loranne, Agius
المصدر: Diabetes, obesitymetabolism. 19(8)
مصطلحات موضوعية: Male, Mice, Inbred C3H, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Pyruvate Kinase, Active Transport, Cell Nucleus, Enzyme Activators, Glucose-6-Phosphate, Fructose, Overweight, Gene Expression Regulation, Enzymologic, Metformin, Thiazoles, Diet, Western, Glucokinase, Fructosediphosphates, Glucose-6-Phosphatase, Hepatocytes, Animals, Hypoglycemic Agents, Rats, Wistar, Promoter Regions, Genetic, Cells, Cultured
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10
المؤلفون: Kylie B. R. Belchamber, Cláudia Henrique da Costa, Peter J. Barnes, Richard Russell, Suzanne L. Traves, Peter Fenwick, Susan J. Tudhope, Louise E. Donnelly
المصدر: The European respiratory journal. 47(4)
مصطلحات موضوعية: 0301 basic medicine, Pulmonary and Respiratory Medicine, Adult, Male, Chemokine, Receptors, CXCR3, Receptors, CCR5, Receptor expression, Respiratory System, CD8-Positive T-Lymphocytes, CXCR3, Ligands, Peripheral blood mononuclear cell, CCL5, Monocytes, 03 medical and health sciences, Chemokine receptor, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Cell Movement, Medicine, Humans, Lung, Aged, Inflammation, biology, business.industry, Monocyte, Chemotaxis, Macrophages, 11 Medical And Health Sciences, Middle Aged, Flow Cytometry, respiratory tract diseases, 030104 developmental biology, medicine.anatomical_structure, 030228 respiratory system, Immunology, biology.protein, Leukocytes, Mononuclear, Female, Chemokines, business
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11
المؤلفون: Howard C. Towle, Robert J. Beynon, Catherine Arden, John L. Petrie, Susan J. Tudhope, Amy J. Claydon, Loranne Agius, Ziad H. Al-Oanzi
المصدر: Diabetes
مصطلحات موضوعية: Male, G6PC, medicine.medical_specialty, Chromatin Immunoprecipitation, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Biology, Real-Time Polymerase Chain Reaction, 03 medical and health sciences, Mice, 0302 clinical medicine, Internal medicine, Gene expression, Glucokinase, Internal Medicine, medicine, Animals, Homeostasis, Rats, Wistar, Cells, Cultured, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, Mice, Inbred BALB C, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Intracellular Signaling Peptides and Proteins, Rats, Endocrinology, Metabolism, Glucose, Liver, biology.protein, Glucose-6-Phosphatase, Hepatocytes, Blood sugar regulation, Carrier Proteins, Intracellular, Glucose 6-phosphatase
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12
المؤلفون: Ursula Straschil, Carol Pridgeon, Louise E. Donnelly, Laurence Bugeon, Peter J. Barnes, Margaret J. Dallman, Susan J. Tudhope, Jonathan R. Lamb, Peter Fenwick
المصدر: Clinical Science. 120:515-524
مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, medicine.medical_treatment, chemical and pharmacologic phenomena, Inflammation, Biology, T-Lymphocytes, Regulatory, Interferon-gamma, Pulmonary Disease, Chronic Obstructive, medicine, Humans, IL-2 receptor, Child, Aged, Aged, 80 and over, Lung, Interleukin-17, Interleukin-2 Receptor alpha Subunit, Interleukin, FOXP3, hemic and immune systems, Pneumonia, General Medicine, Middle Aged, medicine.anatomical_structure, Cytokine, Chronic Disease, Immunology, Interleukin 12, Female, Interleukin 17, medicine.symptom
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13
المؤلفون: John D. Isaacs, Alexei von Delwig, Arthur G. Pratt, Gillian J. Wilson, Jane Falconer, Susan J. Tudhope, Wan-Fai Ng, Tom Woolridge
المصدر: Annals of the Rheumatic Diseases. 69:1873-1879
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Inflammatory arthritis, Immunology, Arthritis, Galactosylceramides, General Biochemistry, Genetics and Molecular Biology, Natural killer cell, Arthritis, Rheumatoid, Diagnosis, Differential, Young Adult, Immune system, Rheumatology, Internal medicine, Osteoarthritis, medicine, Humans, Immunology and Allergy, Lymphocyte Count, Cells, Cultured, Aged, Cell Proliferation, Aged, 80 and over, business.industry, Middle Aged, medicine.disease, Natural killer T cell, Arthralgia, Connective tissue disease, C-Reactive Protein, Methotrexate, medicine.anatomical_structure, Antirheumatic Agents, Rheumatoid arthritis, Natural Killer T-Cells, Female, business, Immunosuppressive Agents
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المؤلفون: Louise E. Donnelly, P. J. Barnes, Peter Fenwick, Susan J. Tudhope
المصدر: European Respiratory Journal. 36:178-186
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Budesonide, medicine.medical_specialty, medicine.medical_treatment, Formoterol Fumarate, Internal medicine, Macrophages, Alveolar, medicine, Humans, Albuterol, Interleukin 8, Glucocorticoids, Salmeterol Xinafoate, business.industry, Monocyte, Adrenergic beta-Agonists, respiratory system, Bronchodilator Agents, respiratory tract diseases, Endocrinology, Cytokine, medicine.anatomical_structure, Ethanolamines, Cytokines, Tumor necrosis factor alpha, Formoterol, Salmeterol, business, hormones, hormone substitutes, and hormone antagonists, medicine.drug
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المؤلفون: Darren Edwards, Neil D. Perkins, James M. Allan, Elaine Willmore, Susan J. Tudhope, Giacomo Berretta, Colin J. Suckling, Andrew Paul, Helen Marr, Aaron Gardner, Louise C. Young, Robin Plevin, Jill E. Hunter, Marie Boyd, Andrew Herridge, Jonathan P. Wallis, David Breen, Simon P. Mackay
المصدر: Blood. 128:3959-3959
مصطلحات موضوعية: Tumor microenvironment, CD40, biology, Kinase, Cell growth, RELB, Immunology, Cell Biology, Hematology, Biochemistry, Compound s, Cell culture, biology.protein, Cancer research, Signal transduction
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16
المؤلفون: Gesa Junge, Charlotte Behardien, Timothy M. Barrow, Laura Woodhouse, Jonathan P. Wallis, Elaine Willmore, Helen Marr, Scott Marshall, Susan J. Tudhope, Gordon Strathdee, Nick Bown
المصدر: Blood. 128:3924-3924
مصطلحات موضوعية: Oncology, Chemotherapy, medicine.medical_specialty, business.industry, medicine.medical_treatment, Immunology, Cancer, Cell Biology, Hematology, medicine.disease, Biochemistry, Fludarabine, Leukemia, Haematopoiesis, medicine.anatomical_structure, Acute lymphocytic leukemia, Internal medicine, DNA methylation, medicine, Bone marrow, business, sub_biomedicalsciences, medicine.drug
وصف الملف: application/pdf
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17
المؤلفون: Muhammad M. Yaqoob, Loranne Agius, Catherine Arden, Julius Kieswich, Jelena Mann, Ziad H. Al-Oanzi, John L. Petrie, Susan J. Tudhope, Howard C. Towle
المصدر: Molecular and cellular biology. 33(4)
مصطلحات موضوعية: Male, Biology, Cell Line, chemistry.chemical_compound, Fructosediphosphates, Animals, Phosphofructokinase 2, Glycolysis, Rats, Wistar, MLX, Glycogen synthase, Carbohydrate-responsive element-binding protein, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Cells, Cultured, Glycogen, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Intracellular Signaling Peptides and Proteins, Cell Biology, Articles, Rats, Protein Transport, Glucose, Glycogen Synthase, Fructose 2,6-bisphosphate, chemistry, Biochemistry, Gene Expression Regulation, biology.protein, Hepatocytes, Trans-Activators, Carrier Proteins
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18
المؤلفون: Ziad H. Al-Oanzi, Alex J. Lange, Howard C. Towle, Loranne Agius, Susan J. Tudhope, Catherine Arden, Kirsty S. Cullen, John L. Petrie
المصدر: The Biochemical journal. 443(1)
مصطلحات موضوعية: Male, Phosphofructokinase-2, Allosteric regulation, Fructose 1,6-bisphosphatase, Active Transport, Cell Nucleus, Carbohydrate metabolism, Deoxyglucose, Biochemistry, chemistry.chemical_compound, Fructosediphosphates, Animals, Phosphofructokinase 2, Glycolysis, Phosphorylation, Rats, Wistar, Promoter Regions, Genetic, Molecular Biology, Cells, Cultured, Xylitol, biology, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Fructose, Hexosamines, Cell Biology, Rats, Glucose, Fructose 2,6-bisphosphate, chemistry, Gene Expression Regulation, Dihydroxyacetone, biology.protein, Glucose-6-Phosphatase, Hepatocytes, Glucose 6-phosphatase, Protein Binding
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المؤلفون: Susan J. Tudhope, John L. Petrie, Fiona C Malcomson, Lloyd Potts, Loranne Agius, Chung-Chi Wang, Muhammad M. Yaqoob, Catherine Arden, Julius Kieswich, Laura J. Hampson
المصدر: Diabetes
مصطلحات موضوعية: Male, medicine.medical_specialty, Serotonin, Indoles, Tetrahydronaphthalenes, Pyridines, Endocrinology, Diabetes and Metabolism, Glycogen debranching enzyme, Glycogen phosphorylase, Internal medicine, Internal Medicine, medicine, Animals, Glycolysis, Pyrroles, Serotonin Antagonists, Rats, Wistar, Phosphorylase kinase, Glycogen synthase, Cells, Cultured, biology, Cyclin-Dependent Kinase 5, Liver Glycogen, Rats, Serotonin Receptor Agonists, Endocrinology, Metabolism, Liver, Glycogenesis, Receptors, Serotonin, biology.protein, Hepatocytes, Metabolic Networks and Pathways
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المؤلفون: Alexei von Delwig, Desa Lilic, Susan J. Tudhope, Wan-Fai Ng
المصدر: Immunology letters. 135(1-2)
مصطلحات موضوعية: Adult, Male, Adolescent, Immunology, Cell, Stimulation, Biology, Gene mutation, medicine, Immunology and Allergy, Humans, Chronic mucocutaneous candidiasis, Child, Gene, Recurrent candida infections, Candida, Cell growth, Candidiasis, Chronic Mucocutaneous, Middle Aged, medicine.disease, Autoimmune regulator, medicine.anatomical_structure, Child, Preschool, Mutation, Natural Killer T-Cells, Female, Transcription Factors
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