المؤلفون: Nies, Vera J. M., Struik, Dicky, Liu, Sihao, Liu, Weilin, Kruit, Janine K., Downes, Michael, van Zutphen, Tim, Verkade, Henkjan J., Evans, Ronald M., Jonker, Johan W.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2022 Oct 01. 119(40), 1-7.

URL الوصول: https://www.jstor.org/stable/27208450

المؤلفون: van der Schoor, Lori WE, Verkade, Henkjan J, Bertolini, Anna, de Wit, Sanne, Mennillo, Elvira, Rettenmeier, Eva, Weber, André A, Havinga, Rick, Valášková, Petra, Jašprová, Jana, Struik, Dicky, Bloks, Vincent W, Chen, Shujuan, Schreuder, Andrea B, Vítek, Libor, Tukey, Robert H, Jonker, Johan W

المصدر: Scientific reports. 11(1)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5cv0z345

المؤلفون: Aaldijk, Alexandra S., Verzijl, Cristy R.C., Jonker, Johan W., Struik, Dicky

المصدر: Aaldijk , A S , Verzijl , C R C , Jonker , J W & Struik , D 2023 , ' Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho ' , Frontiers in endocrinology , vol. 14 , 1150222 . https://doi.org/10.3389/fendo.2023.1150222

مصطلحات موضوعية: Humans, Diabetes Mellitus, Type 2/drug therapy, Fibroblast Growth Factors/genetics, Non-alcoholic Fatty Liver Disease, Signal Transduction, Membrane Proteins/genetics

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/f2edef0b-9d5c-4696-aded-14b2ba727ae5
https://research.rug.nl/en/publications/f2edef0b-9d5c-4696-aded-14b2ba727ae5
https://doi.org/10.3389/fendo.2023.1150222
https://pure.rug.nl/ws/files/667580086/fendo_14_1150222.pdf

المؤلفون: Verzijl, Cristy R C, van de Peppel, Ivo P, Eilers, Roos E, Bloks, Vincent W, Wolters, Justina C, Koehorst, Martijn, Kloosterhuis, Niels J, Havinga, Rick, Jalving, Mathilde, Struik, Dicky, Jonker, Johan W

المصدر: Verzijl , C R C , van de Peppel , I P , Eilers , R E , Bloks , V W , Wolters , J C , Koehorst , M , Kloosterhuis , N J , Havinga , R , Jalving , M , Struik , D & Jonker , J W 2023 , ' Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression ' , Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie , vol. 159 , 114270 . https://doi.org/10.1016/j.biopha.2023.114270

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/da97b802-ab06-4ef4-b713-b0365658ee90
https://research.rug.nl/en/publications/da97b802-ab06-4ef4-b713-b0365658ee90
https://doi.org/10.1016/j.biopha.2023.114270
https://pure.rug.nl/ws/files/563366740/1_s2.0_S0753332223000586_main.pdf

المؤلفون: Verzijl, Cristy R.C., Oldoni, Federico, Loaiza, Natalia, Wolters, Justina, Rimbert, Antoine, Tian, E., Yang, Weiming, Struik, Dicky, Smit, Marieke, Kloosterhuis, Niels, Fernandez, Amy, Samara, Nadine, ten Hagen, Kelly, Dalal, Kruti, Chernish, Aliona, Mccluggage, Peggy, Tabak, Lawrence, Jonker, Johan, Kuivenhoven, Jan Albert

المساهمون: ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), ANR-21-CE14-0051,GENESIS,GPR146: une nouvelle cible contre les maladies cardiométaboliques(2021)

المصدر: ISSN: 2212-8778 ; Molecular metabolism ; https://nantes-universite.hal.science/hal-04060053 ; Molecular metabolism, 2022, 60 (1), pp.101472. ⟨10.1016/j.molmet.2022.101472⟩.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

الاتاحة: https://nantes-universite.hal.science/hal-04060053
https://nantes-universite.hal.science/hal-04060053v1/document
https://nantes-universite.hal.science/hal-04060053v1/file/A_novel_role_for_GalNAc_T2_dependent_glycosylation_in_energy_homeostasis.pdf
https://doi.org/10.1016/j.molmet.2022.101472

المؤلفون: Nies, Vera J M, Struik, Dicky, Liu, Sihao, Liu, Weilin, Kruit, Janine K, Downes, Michael, van Zutphen, Tim, Verkade, Henkjan J, Evans, Ronald M, Jonker, Johan W

المصدر: Nies , V J M , Struik , D , Liu , S , Liu , W , Kruit , J K , Downes , M , van Zutphen , T , Verkade , H J , Evans , R M & Jonker , J W 2022 , ' Autocrine FGF1 signaling promotes glucose uptake in adipocytes ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 119 , no. 40 , e2122382119 . https://doi.org/10.1073/pnas.2122382119

مصطلحات موضوعية: 3T3-L1 Cells, Adipocytes/metabolism, Adipose Tissue, White/metabolism, Animals, Fibroblast Growth Factor 1/genetics, Glucose/metabolism, Glucose Transporter Type 1/genetics, Glucose Transporter Type 4/genetics, Insulin/metabolism, Mice, Proto-Oncogene Proteins c-akt/metabolism, Receptors, Fibroblast Growth Factor/metabolism

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/aa24c527-cf01-4a64-9403-b6824a936909
https://research.rug.nl/en/publications/aa24c527-cf01-4a64-9403-b6824a936909
https://doi.org/10.1073/pnas.2122382119
https://pure.rug.nl/ws/files/246669219/pnas.2122382119.pdf

المؤلفون: Blankestijn, Maaike, Bloks, Vincent W., Struik, Dicky, Huijkman, Nicolette, Kloosterhuis, Niels, Wolters, Justina C., Wanders, Ronald J. A., Vaz, Frederic M., Islinger, Markus, Kuipers, Folkert, van de Sluis, Bart, Groen, Albert K., Verkade, Henkjan J., Jonker, Johan W.

المصدر: Blankestijn , M , Bloks , V W , Struik , D , Huijkman , N , Kloosterhuis , N , Wolters , J C , Wanders , R J A , Vaz , F M , Islinger , M , Kuipers , F , van de Sluis , B , Groen , A K , Verkade , H J & Jonker , J W 2022 , ' Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism ' , Scientific Reports , vol. 12 , no. 1 , 2512 . https://doi.org/10.1038/s41598-022-06479-y

مصطلحات موضوعية: ACTIVATED RECEPTOR-ALPHA, METHYLACYL-COA RACEMASE, BILE-ACID SYNTHESIS, CHAIN FATTY-ACID, PPAR-ALPHA, PHYTANIC ACID, PRISTANIC ACID, MOUSE MODELS, PHYTOL, GENE

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/e7eef6b5-4c05-4dcf-b2fd-758f30a5746e
https://research.rug.nl/en/publications/e7eef6b5-4c05-4dcf-b2fd-758f30a5746e
https://doi.org/10.1038/s41598-022-06479-y
https://pure.rug.nl/ws/files/204287274/s41598_022_06479_y.pdf

المؤلفون: Struik, Dicky

المصدر: Struik , D 2020 , ' Metabolic and mitogenic functions of fibroblast growth factor 1 ' , Doctor of Philosophy , University of Groningen , [Groningen] . https://doi.org/10.33612/diss.133879075

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/d73b1156-4163-40ca-9dd4-8a9a7b1d1cac; urn:ISBN:978-94-034-2879-6

الاتاحة: https://hdl.handle.net/11370/d73b1156-4163-40ca-9dd4-8a9a7b1d1cac
https://research.rug.nl/en/publications/d73b1156-4163-40ca-9dd4-8a9a7b1d1cac
https://doi.org/10.33612/diss.133879075
https://pure.rug.nl/ws/files/133879077/Title_and_contents.pdf
https://pure.rug.nl/ws/files/133879079/Chapter_1.pdf
https://pure.rug.nl/ws/files/133879081/Chapter_2.pdf
https://pure.rug.nl/ws/files/133879083/Chapter_3.pdf
https://pure.rug.nl/ws/files/133879085/Chapter_4.pdf
https://pure.rug.nl/ws/files/133879091/Chapter_7.pdf
https://pure.rug.nl/ws/files/133879101/Appendices.pdf

المؤلفون: van der Schoor, Lori W. E., Verkade, Henkjan J., Bertolini, Anna, de Wit, Sanne, Mennillo, Elvira, Rettenmeier, Eva, Weber, Andre A., Havinga, Rick, Valaskova, Petra, Jasprova, Jana, Struik, Dicky, Bloks, Vincent W., Chen, Shujuan, Schreuder, Andrea B., Vitek, Libor, Tukey, Robert H., Jonker, Johan W.

المصدر: van der Schoor , L W E , Verkade , H J , Bertolini , A , de Wit , S , Mennillo , E , Rettenmeier , E , Weber , A A , Havinga , R , Valaskova , P , Jasprova , J , Struik , D , Bloks , V W , Chen , S , Schreuder , A B , Vitek , L , Tukey , R H & Jonker , J W 2021 , ' Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia ' , Scientific Reports , vol. 11 ....

مصطلحات موضوعية: UDP-GLUCURONOSYLTRANSFERASE ACTIVITY, PREGNANE-X-RECEPTOR, INTESTINAL MICROFLORA, OBETICHOLIC ACID, MOUSE MODEL, BILIRUBIN, PHOTOTHERAPY, EXPRESSION, MANAGEMENT, BIRTH

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/9bf99e8f-1982-4c37-93e5-fd86ee8f1e22
https://research.rug.nl/en/publications/9bf99e8f-1982-4c37-93e5-fd86ee8f1e22
https://doi.org/10.1038/s41598-021-90687-5
https://pure.rug.nl/ws/files/174217732/Potential_of_therapeutic_bile_acids_in_the_treatment_of_neonatal_Hyperbilirubinemia.pdf

المؤلفون: Verzijl, Cristy R C, Van De Peppel, Ivo P, Struik, Dicky, Jonker, Johan W

المصدر: Verzijl , C R C , Van De Peppel , I P , Struik , D & Jonker , J W 2020 , ' Pegbelfermin (BMS-986036) : an investigational PEGylated fibroblast growth factor 21 analogue for the treatment of nonalcoholic steatohepatitis ' , Expert opinion on investigational drugs , vol. 29 , no. 2 , pp. 1-9 . https://doi.org/10.1080/13543784.2020.1708898

مصطلحات موضوعية: Pegbelfermin, FGF21, NAFLD, NASH, FATTY LIVER-DISEASE, BODY-WEIGHT, CONFERS SUSCEPTIBILITY, BARIATRIC SURGERY, REDUCES FEATURES, BETA-KLOTHO, MOUSE MODEL, PATHOGENESIS, ASSOCIATION

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/a8747d25-31f5-42ba-a5d5-37e9fdbc6066
https://research.rug.nl/en/publications/a8747d25-31f5-42ba-a5d5-37e9fdbc6066
https://doi.org/10.1080/13543784.2020.1708898
https://pure.rug.nl/ws/files/111582414/Pegbelfermin_BMS_986036_an_investigational_PEGylated_fibroblast_growth_factor_21_analogue_for_the_treatment_of_nonalcoholic_steatohepatitis.pdf

المؤلفون: Liu, Weilin, Struik, Dicky, Nies, Vera J. M., Jurdzinski, Angelika, Harkema, Liesbeth, de Bruin, Alain, Verkade, Henkjan J., Downes, Michael, Evans, Ronald M., van Zutphen, Tim, Jonker, Johan W.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2016 Feb . 113(8), 2288-2293.

URL الوصول: https://www.jstor.org/stable/26467845

المؤلفون: Bogie, Jeroen, Hoeks, Cindy, Schepers, Melissa, Tiane, Assia, Cuypers, Ann, Leijten, Frank, Chintapakorn, Yupyn, Suttiyut, Thiti, Pornpakakul, Surachai, Struik, Dicky, Kerksiek, Anja, Liu, Hong-Bing, Hellings, Niels, Martinez-Martinez, Pilar, Jonker, Johan W., Dewachter, Ilse, Sijbrands, Eric, Walter, Jochen, Hendriks, Jerome, Groen, Albert, Staels, Bart, Luetjohann, Dieter, Vanmierlo, Tim, Mulder, Monique

المصدر: Bogie , J , Hoeks , C , Schepers , M , Tiane , A , Cuypers , A , Leijten , F , Chintapakorn , Y , Suttiyut , T , Pornpakakul , S , Struik , D , Kerksiek , A , Liu , H-B , Hellings , N , Martinez-Martinez , P , Jonker , J W , Dewachter , I , Sijbrands , E , Walter , J , Hendriks , J , Groen , A , Staels , B , Luetjohann , D , Vanmierlo , T & Mulder , M 2019 , ' ....

مصطلحات موضوعية: LIVER-X RECEPTORS, LXR AGONIST TO901317, HUMAN SERUM-ALBUMIN, PLANT STEROLS, CHOLESTEROL HOMEOSTASIS, BETA-SITOSTEROL, BRAIN, MICE, METABOLISM, ACTIVATION

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/f2775413-a1dd-477d-aed4-31528e507197
https://doi.org/10.1038/s41598-019-41399-4

المؤلفون: Struik, Dicky, Dommerholt, Marleen B, Jonker, Johan W

المصدر: Struik , D , Dommerholt , M B & Jonker , J W 2019 , ' Fibroblast growth factors in control of lipid metabolism : from biological function to clinical application ' , Current Opinion in Lipidology , vol. 30 , no. 3 , pp. 235-243 . https://doi.org/10.1097/MOL.0000000000000599

مصطلحات موضوعية: bile acid metabolism, FGF1, FGF19, FGF21, fibroblast growth factors, lipid metabolism, Y GASTRIC BYPASS, INCREASES ENERGY-EXPENDITURE, BILE-ACIDS, INSULIN SENSITIVITY, PPAR-ALPHA, DECREASED CONSUMPTION, GLUCOSE-METABOLISM, HEPATIC STEATOSIS, CIRCULATING FGF21, ADIPOSE-TISSUE

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/0023ff08-5d76-4028-9e04-1e9f05e8812b
https://research.rug.nl/en/publications/0023ff08-5d76-4028-9e04-1e9f05e8812b
https://doi.org/10.1097/MOL.0000000000000599
https://pure.rug.nl/ws/files/79455704/Fibroblast_growth_factors_in_control_of_lipid_metabolism_from_biological_function_to_clinical_application.pdf

المؤلفون: van der Meer, Thomas P., Artacho-Cordon, Francisco, Swaab, Dick F., Struik, Dicky, Makris, Konstantinos C., Wolffenbuttel, Bruce H. R., Frederiksen, Hanne, van Vliet-Ostaptchouk, Jana V.

المساهمون: van der Meer, Thomas P. Univ Groningen, Univ Med Ctr Groningen, Dept Endocrinol, NL-9713 GZ Groningen, Netherlands, Wolffenbuttel, Bruce H. R. Univ Groningen, Univ Med Ctr Groningen, Dept Endocrinol, NL-9713 GZ Groningen, Netherlands, van Vliet-Ostaptchouk, Jana V. Univ Groningen, Univ Med Ctr Groningen, Dept Endocrinol, NL-9713 GZ Groningen, Netherlands, Artacho-Cordon, Francisco Univ Granada, Radiol & Phys Med Dept, Ibs Granada, Granada 18016, Spain, Swaab, Dick F. Netherlands Inst Neurosci, NL-1105 BA Amsterdam, Netherlands, Struik, Dicky Univ Groningen, Univ Med Ctr Groningen, Dept Pediat, Sect Mol Metab & Nutr, NL-9713 GZ Groningen, Netherlands, Makris, Konstantinos C. Cyprus Univ Technol, Cyprus Int Inst Environm & Publ Hlth, CY-3041 Limassol, Cyprus, Frederiksen, Hanne Copenhagen Univ Hosp, Rigshosp, Dept Growth & Reprod, Blegdamsvej 9, DK-2100 Copenhagen, Denmark, Dutch Diabetes Research Foundation, National Consortium for Healthy Ageing (NCHA) (NCHA NGI), BioSHaRE-EU (Biobank Standardization and Harmonization for Research Excellence in the European Union), International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Danish Center on Endocrine Disrupters

مصطلحات موضوعية: bisphenol-A, methylparaben, phenols, parabens, brain, hypothalamus, obesity, Bisphenol-a concentration, Human adipose-tissue, Environmental chemicals, Human exposure, Association, Adiponectin, Statement, Triclosan

Relation: http://hdl.handle.net/10668/19264; https://www.mdpi.com/1660-4601/14/9/1059/pdf?version=1505381259; 411574400111

الاتاحة: http://hdl.handle.net/10668/19264
https://doi.org/10.3390/ijerph14091059
https://www.mdpi.com/1660-4601/14/9/1059/pdf?version=1505381259

المؤلفون: Struik, Dicky, Sanna, Fabrizio, Fattore, Liana

المصدر: Frontiers in Behavioral Neuroscience ; volume 12 ; ISSN 1662-5153

الاتاحة: http://dx.doi.org/10.3389/fnbeh.2018.00249
https://www.frontiersin.org/article/10.3389/fnbeh.2018.00249/full

المؤلفون: Nies, Vera J. M., Sancar, Gencer, Liu, Weilin, van Zutphen, Tim, Struik, Dicky, Yu, Ruth T., Atkins, Annette R., Evans, Ronald M., Jonker, Johan W., Downes, Michael Robert

المصدر: Nies , V J M , Sancar , G , Liu , W , van Zutphen , T , Struik , D , Yu , R T , Atkins , A R , Evans , R M , Jonker , J W & Downes , M R 2016 , ' Fibroblast Growth Factor Signaling in Metabolic Regulation ' , Frontiers in endocrinology , vol. 6 , 193 . https://doi.org/10.3389/fendo.2015.00193

مصطلحات موضوعية: fibroblast growth factors, metabolic syndrome, FGF signaling, therapeutic potential, FGF1, FGF19, FGF21, INCREASES ENERGY-EXPENDITURE, IMPROVES INSULIN SENSITIVITY, ACTIVATED RECEPTOR-GAMMA, BETA-KLOTHO EXPRESSION, HUMAN SKELETAL-MUSCLE, BROWN ADIPOSE-TISSUE, BILE-ACID SYNTHESIS, FGF21 IN-VIVO, FOOD-INTAKE, WEIGHT-LOSS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/7353e4f6-c633-48a4-bd3d-bc5791fea055
https://research.rug.nl/en/publications/7353e4f6-c633-48a4-bd3d-bc5791fea055
https://doi.org/10.3389/fendo.2015.00193
https://pure.rug.nl/ws/files/39771280/Fibroblast_Growth_Factor_Signaling_in_Metabolic_Regulation.pdf

المؤلفون: Aaldijk, Alexandra (AUTHOR), Struik, Dicky (AUTHOR), Verzijl, Cristy (AUTHOR), Havinga, Rick (AUTHOR), Hovingh, Milaine (AUTHOR), Huijkman, Nicolette (AUTHOR), Smit, Marieke (AUTHOR), van de Sluis, Bart (AUTHOR), Jonker, Johan (AUTHOR)

المصدر: Journal of Hepatology. 2024 Supplement 1, Vol. 80, pS573-S574. 2p.

المؤلفون: Struik, Dicky, Fadda, Paola, Zara, Tamara, Zamberletti, Erica, Rubino, Tiziana, Parolaro, Daniela, Fratta, Walter, Fattore, Liana

المصدر: Struik , D , Fadda , P , Zara , T , Zamberletti , E , Rubino , T , Parolaro , D , Fratta , W & Fattore , L 2017 , ' The anabolic steroid nandrolone alters cannabinoid self-administration and brain CB1 receptor density and function ' , Pharmacological research , vol. 115 , pp. 209-217 . https://doi.org/10.1016/j.phrs.2016.11.031

مصطلحات موضوعية: Cannabinoid CB1 receptors, Anabolic steroid, Nandrolone, Co-abuse, Reward, Drug addiction, MALE-RAT BRAIN, ANDROGENIC STEROIDS, MICE, DEPENDENCE, DECANOATE, REINSTATEMENT, BEHAVIOR, HORMONES, NUCLEUS, SEEKING

Relation: https://research.rug.nl/en/publications/5b8e2777-a94d-4c4e-b03a-bcaf8e966abd

الاتاحة: https://hdl.handle.net/11370/5b8e2777-a94d-4c4e-b03a-bcaf8e966abd
https://research.rug.nl/en/publications/5b8e2777-a94d-4c4e-b03a-bcaf8e966abd
https://doi.org/10.1016/j.phrs.2016.11.031

المؤلفون: Meer, Thomas P van der, Artacho-Cordón, Francisco, Swaab, Dick F, Struik, Dicky, Makris, Konstantinos C, Wolffenbuttel, Bruce H R, Frederiksen, Hanne, Vliet-Ostaptchouk, Jana V van

المصدر: International Journal of Environmental Research and Public Health vol.14 (2017) nr.9 [ISSN 1661-7827]

مصطلحات الفهرس: Journal Article, Artikel, Article

URL: https://pure.knaw.nl/portal/en/publications/4ef11aa3-631a-4856-83a2-6c23967b702e
https://pure.knaw.nl/ws/files/5410366/VanderMeer2017IntJEnvironResPublHealth.pdf
https://pure.knaw.nl/ws/files/5410366/VanderMeer2017IntJEnvironResPublHealth.pdf

المؤلفون: Regenerative Medicine, Stem Cells & Cancer, Dutch Molecular Pathology Centre, LS Pathobiologie, dPB RMSC, Liu, Weilin, Struik, Dicky, Nies, Vera J M, Jurdzinski, Angelika, Harkema, Liesbeth, de Bruin, Alain, Verkade, Henkjan J, Downes, Michael, Evans, Ronald M, van Zutphen, Tim, Jonker, Johan W

URL: https://doi.org/10.1073/pnas.1525093113
http://hdl.handle.net/1874/345915
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