المؤلفون: Kai-Cheng Hsu, Yun-Yi Huang, Jung-Chun Chu, Yu-Wen Huang, Jing-Lan Hu, Tony Eight Lin, Shih-Chung Yen, Jing-Ru Weng, Wei-Jan Huang

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)

مصطلحات موضوعية: Class IIa histone deacetylases (HDACs), structure-activity relationship (SAR), molecular modelling, cancer cells, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/2d0d3d594369440e9a61c2c583b064c2

المؤلفون: Aeyaz Ahmad Bhat, Nitin Tandon, Iqubal Singh

المصدر: Heliyon, Vol 10, Iss 20, Pp e39444- (2024)

مصطلحات موضوعية: α-amylase, α-glucosidase, Antidiabetic activity, Diabetes mellitus, Pyrrolidine, Structure-activity relationship (SAR), Science (General), Q1-390, Social sciences (General), H1-99

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024154758; https://doaj.org/toc/2405-8440

URL الوصول: https://doaj.org/article/c592271ae74c42a7b6be6ca713bb8726

المؤلفون: Harrison T. Shanley, Aya C. Taki, Nghi Nguyen, Tao Wang, Joseph J. Byrne, Ching-Seng Ang, Michael G. Leeming, Nicholas Williamson, Bill C.H. Chang, Abdul Jabbar, Brad E. Sleebs, Robin B. Gasser

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 25, Iss , Pp 100534- (2024)

مصطلحات موضوعية: Anthelmintic discovery, Haemonchus contortus, Caenorhabditis elegans, Structure-activity relationship (SAR), Target identification, Thermal proteome profiling, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320724000150; https://doaj.org/toc/2211-3207

URL الوصول: https://doaj.org/article/e3738831bebf4b19be4951ffbbc3215f

المؤلفون: Norris, James K. S.

مصطلحات موضوعية: Lysine Specific Demethylase 1A, LSD1, Proteolysis Targeting Chimeras (PROTACs), epigenetics, structure-activity-relationship (SAR), thesis

URL الوصول: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.850064

المؤلفون: Verónica I. Dumit, Yuk‐Chien Liu, Aileen Bahl, Pekka Kohonen, Roland C. Grafström, Penny Nymark, Christine Müller‐Graf, Andrea Haase, Mario Pink

المصدر: Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)

مصطلحات موضوعية: bioinformatics in nanosafety, carbon nanomaterials, fiber toxicity assessment, integrative omics meta‐analysis, nanofiber rigidity prediction, structure‐activity‐relationship (SAR), Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2198-3844

URL الوصول: https://doaj.org/article/6b63502ec35944bbb92b3cb3094902c0

المؤلفون: Biswajit Kundu, Szabolcs Dvorácskó, Abhishek Basu, Lenny Pommerolle, Kyu Ah Kim, Casey M. Wood, Eve Gibbs, Madeline Behee, Nadya I. Tarasova, Resat Cinar, Malliga R. Iyer

المصدر: Molecules, Vol 29, Iss 13, p 3036 (2024)

مصطلحات موضوعية: soluble epoxide hydrolase (sEH), epoxyeicosatrienoic acids (EETs), structure-activity relationship (SAR), in vitro ADME, molecular docking, acute lung injury (ALI), Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/13/3036; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/082c48c1d63a4249a7e91acb02de8c5e

المؤلفون: Ghazala Muteeb, Md Tabish Rehman, Bibhusita Pani, Rizwan Hasan Khan

المصدر: Frontiers in Molecular Biosciences, Vol 10 (2024)

مصطلحات موضوعية: immunoinformatics, antimicrobial resistance, in-silico, African catfish antimicrobial peptides (ACAPs), structure-activity relationship (SAR), Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1342702/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/829f5eb507b148e4a4e882535510341c

المؤلفون: Jehan Y. Al-Humaidi, Lamia A. Albedair, Basant Farag, Magdi E.A. Zaki, Yousef E. Mukhrish, Sobhi M. Gomha

المصدر: Results in Chemistry, Vol 7, Iss , Pp 101475- (2024)

مصطلحات موضوعية: Hydrazonoyl halides, 1,3,4-Thiadiazoles, 1,3-Thiazoles, Cytotoxicity evaluation, Structure activity relationship (SAR), Molecular docking studies, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715624001711; https://doaj.org/toc/2211-7156

URL الوصول: https://doaj.org/article/4f9abcbcdd9d4290aa7effec5214cbdb

المؤلفون: Sheng Wang, Jian-Guo Yang, Kuanrong Rong, Huan-Huan Li, Chengyao Wu, Wenjian Tang

المصدر: International Journal of Molecular Sciences ; Volume 25 ; Issue 22 ; Pages: 11888

مصطلحات موضوعية: structure–activity relationship (SAR), structure–tissue exposure/selectivity relationship (STR), drug development and optimization, cannabidiol, carbamate, butyrocholinesterase

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Informatics; https://dx.doi.org/10.3390/ijms252211888

الاتاحة: https://doi.org/10.3390/ijms252211888

المؤلفون: Jin-Pyo An, Yu Wang, Steven D. Munger, Xixuan Tang

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Neuroscience, Pharmacology, Science Policy, Mental Health, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Taste-active compounds, non-caloric sweeteners, natural product, structural diversity, structure-activity relationship (SAR)

Relation: https://figshare.com/articles/journal_contribution/A_review_on_natural_sweeteners_sweet_taste_modulators_and_bitter_masking_compounds_structure-activity_strategies_for_the_discovery_of_novel_taste_molecules/25427519

الاتاحة: https://doi.org/10.6084/m9.figshare.25427519.v1

المؤلفون: Aqsa Salamat, Naveen Kosar, Ayesha Mohyuddin, Muhammad Imran, Muhammad Nauman Zahid, Tariq Mahmood

المصدر: Molecules, Vol 29, Iss 5, p 1144 (2024)

مصطلحات موضوعية: COVID-19, density functional theory (DFT), molecular docking (MD), molecular dynamics simulation, structure–activity relationship (SAR), pharmacokinetics, Organic chemistry, QD241-441

Relation: https://www.mdpi.com/1420-3049/29/5/1144; https://doaj.org/toc/1420-3049; https://doaj.org/article/ff3475c0e7184b829df9f41386d263b9

الاتاحة: https://doi.org/10.3390/molecules29051144
https://doaj.org/article/ff3475c0e7184b829df9f41386d263b9

المؤلفون: Sabyasachi Banerjee, Sougata Mukherjee, Priyobrata Nath, Agnish Mukherjee, Souvik Mukherjee, S.K. Ashok Kumar, Sourav De, Subhasis Banerjee

المصدر: Results in Chemistry, Vol 6, Iss , Pp 101013- (2023)

مصطلحات موضوعية: Benzimidazole, Fused heterocyclic, Structure–activity relationship (SAR), Medicinal chemistry, Pharmacological activity, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715623002527; https://doaj.org/toc/2211-7156

URL الوصول: https://doaj.org/article/2416f7b1ba5f47f9a49f14805b17081d

المؤلفون: Jung-Chun Chu, Hui-Ju Tseng, Sung-Bau Lee, Kai-Cheng Hsu, Ling-Wei Hsin, Ru-Hao Liang, Tony Eight Lin, Nain-Chu Gao, Liang-Chieh Chen, Wan-Hsun Lu, Andrew H.-J Wang, Wei-Jan Huang

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)

مصطلحات موضوعية: Histone deacetylase (HDAC), phenoxazine, structure-activity relationship (SAR), neuron cells, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/7b58580986544041963eeb2da4256825

المؤلفون: Wilt, Stephanie, Kodani, Sean, Le, Thanh NH, Nguyen, Lato, Vo, Nghi, Ly, Tanya, Rodriguez, Mark, Hudson, Paula K, Morisseau, Christophe, Hammock, Bruce D, Pecic, Stevan

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Neurodegenerative, Chronic Pain, Pain Research, Neurosciences, Peripheral Neuropathy, 5.1 Pharmaceuticals, Humans, Models, Molecular, Molecular Docking Simulation, Pain, Structure-Activity Relationship, Structure-Activity Relationship (SAR) study, Enzyme inhibition, Designed multiple ligands, Molecular modeling, Docking experiments, ADMET predictions, Organic Chemistry, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2pb4k5v5
https://escholarship.org/content/qt2pb4k5v5/qt2pb4k5v5.pdf

المؤلفون: Roman Memedovski, Matías Preza, Joachim Müller, Tobias Kämpfer, Reto Rufener, Marcus Vinicius Nora de Souza, Emerson Teixeira da Silva, Gabriel Fernandes de Andrade, Sophie Braga, Anne-Christine Uldry, Natasha Buchs, Manfred Heller, Britta Lundström-Stadelmann

المصدر: International Journal for Parasitology: Drugs and Drug Resistance, Vol 21, Iss , Pp 114-124 (2023)

مصطلحات موضوعية: Echinococcus multilocularis, Alveolar echinococcosis, Mefloquine, Structure-activity relationship (SAR), Mode of action, nLC-MS/MS, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320723000106; https://doaj.org/toc/2211-3207

URL الوصول: https://doaj.org/article/89a49aeeca2f46a99fa3bbefacf831fb

المؤلفون: Lai, Qinhuai, Wang, Zhijia, Wu, Chengyong, Zhang, Ruofei, Li, Leyan, Tao, Yiran, Mo, Dan, Zhang, Jifa, Gou, Lantu, Wang, Yuxi

المصدر: Eur J Med Chem ; ISSN:1768-3254 ; Volume:283

مصطلحات موضوعية: Antitumor, Co-crystal structure, Colchicine binding site inhibitors (CBSIs), Quinazoline-4-tetrahydroquinoline, Structure-activity relationship (SAR), Tubulin

Relation: https://doi.org/10.1016/j.ejmech.2024.117139; https://pubmed.ncbi.nlm.nih.gov/39662284

الاتاحة: https://doi.org/10.1016/j.ejmech.2024.117139
https://pubmed.ncbi.nlm.nih.gov/39662284

المؤلفون: Dóra Balázs, Tamás Marik, András Szekeres, Csaba Vágvölgyi, László Kredics, Chetna Tyagi

المصدر: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1860-1873 (2023)

مصطلحات موضوعية: Trichoderma, Peptaibols, Molecular dynamics simulations, Peptide folding, Structure-activity relationship (SAR), Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037023000922; https://doaj.org/toc/2001-0370

URL الوصول: https://doaj.org/article/124c2d5430dc46d7a052d7d44bdc8c9e

المؤلفون: Ravi Tripathi, Abiodun Anifowose, Wen Lu, Xiaoxiao Yang, Binghe Wang

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2370-2381 (2022)

مصطلحات موضوعية: p53, MDM2, anthraquinone, cancer, structure–activity relationship (SAR), Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/1b1c5832c6254715b94a2b961073e185

المؤلفون: Ivan Gando, Manuel Becerra Flores, I.-Shan Chen, Hua-Qian Yang, Tomoe Y. Nakamura, Timothy J. Cardozo, William A. Coetzee

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: KATP channels, kir6.2, potassium channel opener, structure-activity relationship (SAR), cardioprotection, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1197257/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/3e472d27d00c4839be30fd2fd463659c

المؤلفون: Wei Gao, Hongxiang Hu, Lipeng Dai, Miao He, Hebao Yuan, Huixia Zhang, Jinhui Liao, Bo Wen, Yan Li, Maria Palmisano, Mohamed Dit Mady Traore, Simon Zhou, Duxin Sun

المصدر: Acta Pharmaceutica Sinica B, Vol 12, Iss 5, Pp 2462-2478 (2022)

مصطلحات موضوعية: Structure‒activity-relationship (SAR), Structure-tissue exposure/selectivity relationship (STR), Drug optimization, Clinical efficacy/toxicity, Drug development, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383522000715; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/8f3478b4480b4cadbce522dd147c6570