المؤلفون: Maurice Steenhuis (10968314), Federico Corona (10968317), Corinne M. ten Hagen-Jongman (10968320), Waldemar Vollmer (175986), Dominique Lambin (9941681), Philippe Selhorst (4799031), Hugo Klaassen (2035108), Matthias Versele (10968323), Patrick Chaltin (1656292), Joen Luirink (243945)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Pharmacology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, OMP biogenesis mutants, compound 2, novel target, BAM-dependent OMP, β- barrel assembly machine, screening approach, refolding assay, Cell Envelope Stress Reporter Assays, 316 953, σ E, antibiotic, β- barrel type OM protein, intracellular heat-shock response, Escherichia coli, compounds 2, Identify BAM Complex Inhibitors, inhibitor, Gram-negative bacteria, Rcs stress, OM integrity, 316 953 compounds, Rcs stress responses, cell envelope σ E, permeability barrier

Relation: https://figshare.com/articles/journal_contribution/Combining_Cell_Envelope_Stress_Reporter_Assays_in_a_Screening_Approach_to_Identify_BAM_Complex_Inhibitors/14780015

الاتاحة: https://doi.org/10.1021/acsinfecdis.0c00728.s001

المؤلفون: Elhendawi, Mona, Lawrence, Melanie, Davies, Jamie, Sjögren, Anna-Karin, Morlock, Michaela, Palakkan, Anwar, Hohenstein, Peter, Seidl, LF, Liu, Weijia, Liu, S

المساهمون: BBSRC - Biotechnology and Biological Sciences Research Council, MRC - Medical Research Council, Kidney Research UK, University of Edinburgh, Wellcome Trust, Elhendawi, Mona

مصطلحات موضوعية: renal organoid, hiPSC, kidney, nephrotoxicity, oxidative stress, transporters, oxidative stress reporter, pluripotent, toxicology, Biological Sciences

وصف الملف: application/zip

Relation: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE195642; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8861638/; Lawrence, M. L., Elhendawi, M., Morlock, M., Liu, W., Liu, S., Palakkan, A., Seidl, L. F., Hohenstein, P., Sjögren, A. K., & Davies, J. A. (2022). Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced toxicity. iScience, 25(3), 103884. https://doi.org/10.1016/j.isci.2022.103884; Elhendawi, Mona; Lawrence, Melanie; Davies, Jamie; Sjögren, Anna-Karin; Morlock, Michaela; Palakkan, Anwar; Hohenstein, Peter; Seidl, LF; Liu, Weijia; Liu, S. (2022). Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced nephrotoxicity, [dataset]. University of Edinburgh. Edinburgh Medical School. https://doi.org/10.7488/ds/3414.; https://hdl.handle.net/10283/4372; https://doi.org/10.7488/ds/3414

الاتاحة: https://hdl.handle.net/10283/4372
https://doi.org/10.7488/ds/3414

المؤلفون: Jacob R, Manjarrez, Roger, Mailler

المصدر: Heliyon

مصطلحات موضوعية: Immobilization, Sodium azide, Stress reporter, Dose-response relationship, Levamisole, Oxidative stress, Anesthetic, Genetics, Promoter, Gene expression, Caenorhabditis elegans, Article, Gene regulation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::2c4f248c67d1a5f3a21740cd44756c4b
https://pubmed.ncbi.nlm.nih.gov/32671240