المؤلفون: Elhemely, Mai A., Belgath, Asma A., El-Sayed, Sherihan, Burusco, Kepa K., Kadirvel, Manikandan, Tirella, Annalisa, Finegan, Katherine, Bryce, Richard A., Stratford, Ian J., Freeman, Sally

المساهمون: Elhemely, Mai A., Belgath, Asma A., El-Sayed, Sherihan, Burusco, Kepa K., Kadirvel, Manikandan, Tirella, Annalisa, Finegan, Katherine, Bryce, Richard A., Stratford, Ian J., Freeman, Sally

Relation: info:eu-repo/semantics/altIdentifier/pmid/35290041; info:eu-repo/semantics/altIdentifier/wos/WOS:000790749000022; volume:65; issue:6; firstpage:4783; lastpage:4797; numberofpages:15; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11572/346904

الاتاحة: https://hdl.handle.net/11572/346904
https://doi.org/10.1021/acs.jmedchem.1c01936

المؤلفون: Belgath, Asma A., Emam, Aya M., Taujanskas, Joshua, Bryce, Richard A., Freeman, Sally, Stratford, Ian J.

المصدر: International Journal of Molecular Sciences; Nov2024, Vol. 25 Issue 22, p12025, 23p

مصطلحات موضوعية: BENZOTHIAZOLE, DOUBLE bonds, QUINONE, RING formation (Chemistry), CANCER treatment

المؤلفون: Spadea, Alice, Tirella, Annalisa, Rios de la Rosa, Julio Manuel, Lallana, Enrique, Mehibel, Manal, Telfer, Brian, Tirelli, Nicola, Lawrence, Margaret Jayne, Williams, Kaye J., Stratford, Ian J., Ashford, Marianne

المصدر: Pharmaceutics; Oct2024, Vol. 16 Issue 10, p1286, 18p

مصطلحات موضوعية: GENE expression, SMALL interfering RNA, PANCREATIC cancer, HYALURONIC acid, GENE therapy, GENE silencing

المؤلفون: Atiomo, William, Shafiee, Mohamad Nasir, Chapman, Caroline, Metzler, Veronika M., Abouzeid, Jad, Latif, Ayşe, Chadwick, Amy, Kitson, Sarah, Sivalingam, Vanitha N., Stratford, Ian J., Rutland, Catrin S., Persson, Jenny L., Ødum, Niels, Fuentes-Utrilla, Pablo, Jeyapalan, Jennie N., Heery, David M, Crosbie, Emma J., Mongan, Nigel P.

المصدر: Clinical Endocrinology BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 87(5):557-565

مصطلحات موضوعية: endometrial cancer, endometrium, NQO1, polycystic ovary syndrome, Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology

URL الوصول: https://lup.lub.lu.se/record/5dc47e69-c983-457c-a82f-cf1eb38c432b
http://dx.doi.org/10.1111/cen.13436

المؤلفون: Stratford, Ian James

المصدر: Al-Balqa Journal for Research and Studies البلقاء للبحوث والدراسات

مصطلحات موضوعية: Cancer Research, School of Pharmacy, Chemistry

وصف الملف: application/pdf

Relation: https://digitalcommons.aaru.edu.jo/albalqa/vol14/iss1/7; https://digitalcommons.aaru.edu.jo/context/albalqa/article/1155/viewcontent/0140010345.pdf

الاتاحة: https://digitalcommons.aaru.edu.jo/albalqa/vol14/iss1/7
https://digitalcommons.aaru.edu.jo/context/albalqa/article/1155/viewcontent/0140010345.pdf

المؤلفون: Hussein, Buthaina, Ikhmais, Balqis, Kadirvel, Manikandan, Magwaza, Rachael N., Halbert, Gavin, Bryce, Richard A., Stratford, Ian J., Freeman, Sally

مصطلحات موضوعية: Therapeutics. Pharmacology

وصف الملف: text

Relation: https://strathprints.strath.ac.uk/88494/1/Hussein-etal-EJMC-2019-Discovery-of-potent-4-aminoquinoline-hydrazone-inhibitors.pdf; Hussein, Buthaina and Ikhmais, Balqis and Kadirvel, Manikandan and Magwaza, Rachael N. and Halbert, Gavin and Bryce, Richard A. and Stratford, Ian J. and Freeman, Sally (2019 ) Discovery of potent 4-aminoquinoline hydrazone inhibitors of NRH:quinoneoxidoreductase-2 (NQO2). European Journal of Medicinal Chemistry , 182. 111649. ISSN 0223-5234

الاتاحة: https://strathprints.strath.ac.uk/88494/
https://doi.org/10.1016/j.ejmech.2019.111649

المؤلفون: Megarity, Clare F., Abdel-Aal Bettley, Hoda, Caraher, M. Clare, Scott, Katherine A., Whitehead, Roger C., Jowitt, Thomas A., Gutierrez, Aldo, Bryce, Richard A., Nolan, Karen A., Stratford, Ian J., Timson, David J.

المصدر: Megarity , C F , Abdel-Aal Bettley , H , Caraher , M C , Scott , K A , Whitehead , R C , Jowitt , T A , Gutierrez , A , Bryce , R A , Nolan , K A , Stratford , I J & Timson , D J 2019 , ' Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1) ' , CHEMBIOCHEM , vol. 20 , no. 22 , pp. 2841-2849 . https://doi.org/10.1002/cbic.201900313

مصطلحات موضوعية: cancer-associated proteins, elastic network models, enzyme cooperativity, protein flexibility, quinone oxidoreductases

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

الاتاحة: https://research.manchester.ac.uk/en/publications/b19365fc-677f-4182-bbe6-16aac8fb102b
https://doi.org/10.1002/cbic.201900313
https://pure.manchester.ac.uk/ws/files/112798496/ChemBioChem_SUBMIT_R1.docx
http://www.scopus.com/inward/record.url?scp=85068889898&partnerID=8YFLogxK
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201900313

المؤلفون: Rios de la Rosa, Julio M., Pingrajai, Ponpawee, Pelliccia, Maria, Spadea, Alice, Lallana, Enrique, Gennari, Arianna, Stratford, Ian J., Rocchia, Walter, Tirella, Annalisa, Tirelli, Nicola

المساهمون: Engineering and Physical Sciences Research Council, University of Manchester, Biotechnology and Biological Sciences Research Council, Innovate UK, FP7 Health

المصدر: Advanced Healthcare Materials ; volume 8, issue 24 ; ISSN 2192-2640 2192-2659

الاتاحة: http://dx.doi.org/10.1002/adhm.201901182
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fadhm.201901182
https://onlinelibrary.wiley.com/doi/pdf/10.1002/adhm.201901182
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/adhm.201901182

المؤلفون: Sivalingam, Vanitha N., Latif, Ayşe, Kitson, Sarah, McVey, Rhona, Finegan, Katherine G., Marshall, Kay, Lisanti, Michael P., Sotgia, Federica, Stratford, Ian J., Crosbie, Emma J.

المساهمون: DH | National Institute for Health Research

المصدر: British Journal of Cancer ; volume 122, issue 1, page 62-71 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/s41416-019-0627-y
http://www.nature.com/articles/s41416-019-0627-y.pdf
http://www.nature.com/articles/s41416-019-0627-y

المؤلفون: Mehibel, Manal, Ortiz-martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.

المصدر: Mehibel , M , Ortiz-martinez , F , Voelxen , N , Boyers , A , Chadwick , A , Telfer , B A , Mueller-klieser , W , West , C M , Critchlow , S E , Williams , K J & Stratford , I J 2018 , ' Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters ' , Scientific Reports , vol. 8 , no. 1 , 16804 . https://doi.org/10.1038/s41598-018-35103-1

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/3ce33dc7-bdcb-4096-96eb-6a3f59388d59
https://doi.org/10.1038/s41598-018-35103-1
http://www.nature.com/articles/s41598-018-35103-1

المؤلفون: Sharma, Ricky A., Plummer, Ruth, Stock, Julie K., Greenhalgh, Tessa A., Ataman, Ozlem, Kelly, Stephen, Clay, Robert, Adams, Richard A., Baird, Richard D., Billingham, Lucinda, Brown, Sarah R., Buckland, Sean, Bulbeck, Helen, Chalmers, Anthony J., Clack, Glen, Cranston, Aaron N., Damstrup, Lars, Ferraldeschi, Roberta, Forster, Martin D., Golec, Julian, Hagan, Russell M., Hall, Emma, Hanauske, Axel-R., Harrington, Kevin J., Haswell, Tom, Hawkins, Maria A., Illidge, Tim, Jones, Hazel, Kennedy, Andrew S., McDonald, Fiona, Melcher, Thorsten, O'Connor, James P. B., Pollard, John R., Saunders, Mark P., Sebag-Montefiore, David, Smitt, Melanie, Staffurth, John, Stratford, Ian J., Wedge, Stephen R.

وصف الملف: text

Relation: http://eprints.gla.ac.uk/168118/1/168118.pdf; Sharma, R. A. et al. (2018) Clinical development of new drug–radiotherapy combinations. Nature Reviews Clinical Oncology , 13(10), pp. 627-642. (doi:10.1038/nrclinonc.2016.79 ) (PMID:27245279)

الاتاحة: http://eprints.gla.ac.uk/168118/
http://eprints.gla.ac.uk/168118/1/168118.pdf

المؤلفون: Latif, Ayşe, Chadwick, Amy L, Kitson, Sarah J, Gregson, Hannah J, Sivalingam, Vanitha N, Bolton, James, McVey, Rhona J, Roberts, Stephen A, Marshall, Kay M, Williams, Kaye J, Stratford, Ian J, Crosbie, Emma J

المصدر: Latif , A , Chadwick , A L , Kitson , S J , Gregson , H J , Sivalingam , V N , Bolton , J , McVey , R J , Roberts , S A , Marshall , K M , Williams , K J , Stratford , I J & Crosbie , E J 2017 , ' Monocarboxylate Transporter 1 (MCT1) is an independent prognostic biomarker in endometrial cancer ' , BMC Clinical Pathology , vol. 17 , pp. 27 . https://doi.org/10.1186/s12907-017-0067-7

Relation: https://research.manchester.ac.uk/en/publications/8b156b5c-b6d5-445b-a89e-ad509b713847

الاتاحة: https://research.manchester.ac.uk/en/publications/8b156b5c-b6d5-445b-a89e-ad509b713847
https://doi.org/10.1186/s12907-017-0067-7

المؤلفون: Greenwood, Daniel, Stratford, Ian

المصدر: Greenwood , D & Stratford , I 2017 , ' A review of dose escalation methods in first-in-human small molecule oncology clinical trials ' , Trials , vol. 18 , pp. 233-234 . https://doi.org/10.1186/s13063-017-1902-y

الاتاحة: https://research.manchester.ac.uk/en/publications/1ba4407b-22b2-4172-abba-b900f6b5ebf7
https://doi.org/10.1186/s13063-017-1902-y

المؤلفون: Allison, Simon J, Sadiq, Maria, Baronou, Efstathia, Cooper, Patricia, Dunnill, Christopher, Georgopoulos, Nikolaos T, Latif, Ayse, Shepherd, Samantha, Shnyder, Steven D., Stratford, Ian, Wheelhouse, Richard, Willans, Charlotte, Phillips, Roger

المصدر: Allison , S J , Sadiq , M , Baronou , E , Cooper , P , Dunnill , C , Georgopoulos , N T , Latif , A , Shepherd , S , Shnyder , S D , Stratford , I , Wheelhouse , R , Willans , C & Phillips , R 2017 , ' Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands. ' , Cancer Letters , vol. 403 , pp. 98–107 . https://doi.org/10.1016/j.canlet.2017.04.041

مصطلحات موضوعية: Silver-N-heterocycle carbene, Thioredoxin reductase inhibitor, Topoisomerase inhibitor, PARP1 inhibitor, Glycolytic inhibitor

وصف الملف: application/pdf

الاتاحة: https://research.manchester.ac.uk/en/publications/788e338c-bc9f-4a14-b25f-a6ec2264fdcf
https://doi.org/10.1016/j.canlet.2017.04.041
https://pure.manchester.ac.uk/ws/files/57033841/Preclinical_anti_cancer_activity_and_multiple_mechanisms_of_action_of_a_cationic_silver_complex_bearing_N_heterocyclic_carbene_ligands.pdf

المؤلفون: Searle, Emma J, Telfer, Brian A, Mukherjee, Debayan, Forster, Duncan M, Davies, Barry R, Williams, Kaye J, Stratford, Ian J, Illidge, Tim M

المساهمون: AstraZeneca, Cancer Research UK

المصدر: EMBO Molecular Medicine ; volume 9, issue 12, page 1646-1659 ; ISSN 1757-4676 1757-4684

الاتاحة: http://dx.doi.org/10.15252/emmm.201707767
https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201707767
https://onlinelibrary.wiley.com/doi/full-xml/10.15252/emmm.201707767
https://www.embopress.org/doi/pdf/10.15252/emmm.201707767

المؤلفون: Christou, Stephania, Edwards, Alyn C., Kaskun, Songul, Pritchard, Robin G., Quayle, Peter, Song, Yiwei, Stratford, Ian J., Williams, Katharine F., Whitehead, Roger C.

المصدر: Tetrahedron ; volume 73, issue 9, page 1295 ; ISSN 0040-4020

الاتاحة: https://doi.org/10.1016/j.tet.2017.01.040
https://api.elsevier.com/content/article/PII:S0040402017300637?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0040402017300637?httpAccept=text/plain

المؤلفون: Singh, Simendra, Cowen, Rachel L., Chinje, Edwin C., Stratford, Ian J.

المصدر: Radiation Research, 2009 May 01. 171(5), 572-580.

URL الوصول: https://www.jstor.org/stable/40212798

المؤلفون: Stratford, Ian, Sharma, Ricky, Plummer, Ruth, K Stock, Julie, A Greenhalgh, Tessa, Atamar, Ozlem, Kelly, Stephen, Clay, Robert, Adams, Richard, D Baird, Richard, Billingham, Lucinda, R Brown, Sarah, Buckland, Sean, Bulbeck, Helen, J Chalmers, Anthony, Clack, Glen, N Cranston, Aaron, Damstrup, Lars, Ferraldeschi, Roberta, D Forster, Martin, Golec, Julian, M Hagan, Russell, Hall, Emma, Hanauske, Axel-R, Harrington, Kevin J, Haswell, Tom, A Hawkins, Maria, Illidge, Timothy, Jones, Hazel, S Kennedy, Andrew, McDonald, Fiona, Melcher, Thorsten, O'Connor, James, R Pollard, John, Saunders, Mark P, Sebag-Montefiore, David, Smitt, Melanie, Staffurth, John N, Wedge, Stephen R

المصدر: Stratford , I , Sharma , R , Plummer , R , K Stock , J , A Greenhalgh , T , Atamar , O , Kelly , S , Clay , R , Adams , R , D Baird , R , Billingham , L , R Brown , S , Buckland , S , Bulbeck , H , J Chalmers , A , Clack , G , N Cranston , A , Damstrup , L , Ferraldeschi , R , D Forster , M , Golec , J , M Hagan , R , Hall , E ....

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

Relation: https://research.manchester.ac.uk/en/publications/4e78c684-467a-4f54-826f-d82a17883509

الاتاحة: https://research.manchester.ac.uk/en/publications/4e78c684-467a-4f54-826f-d82a17883509
https://doi.org/10.1038/nrclinonc.2016.79

المؤلفون: Searle, Emma, Telfer, Brian, Forster, Duncan, Davies, Barry R, Stratford, Ian, Illidge, Timothy, Williams, Kaye

المصدر: Searle , E , Telfer , B , Forster , D , Davies , B R , Stratford , I , Illidge , T & Williams , K 2016 , ' Treatment with the novel Akt inhibitor AZD5363 following radiotherapy improves tumour control in mouse models of head and neck cancer ' , European Journal of Cancer , vol. 61 , no. Supplement 1 , pp. S162 . https://doi.org/10.1016/S0959-8049(16)61573-3

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/5691d746-17ec-4afe-b06d-b10e5823368e
https://doi.org/10.1016/S0959-8049(16)61573-3

المؤلفون: Searle, Emma, Telfer, Brian, Forster, Duncan, Davies, Barry R., Stratford, Ian, Illidge, Timothy, Williams, Kaye

المصدر: Searle , E , Telfer , B , Forster , D , Davies , B R , Stratford , I , Illidge , T & Williams , K 2016 , ' The novel Akt inhibitor AZD5363 following radiotherapy improves tumor control in mouse models of head and neck cancer ' , Cancer Research , vol. 76 , no. 14 , pp. 3042 . https://doi.org/10.1158/1538-7445.AM2016-3042

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/9c9f3d48-db47-4751-9487-e0aeaa279bb9
https://doi.org/10.1158/1538-7445.AM2016-3042