المؤلفون: Joseph T. Repine, Lorraine Kathleen Fay, Favor David, Hyacinth Akunne, Kim Nicholls, Bradley Snyder, Liming Zhang, Kevin A. Serpa, Douglas S. Johnson, Lawrence W. Fitzgerald, Andrew D. White, Chung Choi, Steven Z. Whetzel

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:2621-2625

مصطلحات موضوعية: Male, Bipolar Disorder, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Catalepsy, Biochemistry, Partial agonist, Chemical synthesis, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Naphthyridines, Antipsychotic, Receptor, Piperazine, Molecular Biology, Molecular Structure, Receptors, Dopamine D2, Chemistry, Aryl, Organic Chemistry, Haplorhini, medicine.disease, Rats, Schizophrenia, Molecular Medicine, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a73015fc859258fce499a6bc0925b0a
https://doi.org/10.1016/j.bmcl.2011.01.059

المؤلفون: Steven Z. Whetzel, Thomas A. Pugsley, Yu-Hsin Shih, Hyacinth C. Akunne, Lynn M. Georgic

المصدر: Journal of Neurochemistry. 69:2363-2368

مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, Quinpirole, Intrinsic activity, medicine.drug_class, Dopamine, CHO Cells, Biochemistry, 5-Hydroxytryptophan, Cellular and Molecular Neuroscience, Dopamine receptor D3, Cricetinae, Internal medicine, Oxazines, medicine, Animals, Humans, Benzopyrans, Drug Interactions, Receptors, Dopamine D2, Chemistry, Receptors, Dopamine D3, Antagonist, Brain, Rats, Inbred Strains, Receptor antagonist, Dihydroxyphenylalanine, Rats, Dopamine D2 Receptor Antagonists, Endocrinology, Dopamine Agonists, Benzimidazoles, Receptor antagonist activity, Thymidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762d499cb44ed0ec5b92f90b361a115a
https://doi.org/10.1046/j.1471-4159.1997.69062363.x

المؤلفون: Kim Zoski, Lawrence D. Wise, Steven Z. Whetzel, Lynn M. Georgic, Robert G. MacKenzie, Y H Shih, L. W. Cooke, T. A. Pugsley, Thomas G. Heffner, Leonard T. Meltzer, Michael Duff Davis, David J. Wustrow, Hyacinth Akunne

المصدر: Neuropharmacology. 39:1197-1210

مصطلحات موضوعية: Male, Agonist, Biogenic Amines, medicine.medical_specialty, Tetrahydronaphthalenes, medicine.drug_class, CHO Cells, Thiophenes, Pharmacology, Partial agonist, Piperazines, Cellular and Molecular Neuroscience, Quinpirole, Dopamine, Cricetinae, Internal medicine, medicine, Animals, Humans, Rats, Long-Evans, Receptor, Cells, Cultured, Brain Chemistry, 8-Hydroxy-2-(di-n-propylamino)tetralin, Membranes, Receptors, Dopamine D2, Chemistry, Receptors, Dopamine D3, Benzazepines, Rats, Serotonin Receptor Agonists, Electrophysiology, Neostriatum, Pyrimidines, Endocrinology, Mechanism of action, Spiperone, Receptors, Serotonin, Dopamine Agonists, Autoreceptor, Dopamine Antagonists, Serotonin, medicine.symptom, Receptors, Serotonin, 5-HT1, Antipsychotic Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e3ba7056cf29abaab22525fce8f134
https://doi.org/10.1016/s0028-3908(99)00224-5

المؤلفون: David Juergen Wustrow, Thomas G. Heffner, Michael Duff Davis, Lynn M. Georgic, Suzanne Ross Kesten, Anthony C. Blackburn, Ronald Rubin, Thomas Richard Belliotti, Shelly Ann Glase, Ann E. Corbin, Hyacinth Akunne, T. A. Pugsley, Norman L. Colbry, Steven Z. Whetzel, Kim Zoski, Lawrence D. Wise, D. R. Johnson

المصدر: Journal of Medicinal Chemistry. 41:760-771

مصطلحات موضوعية: Male, Intrinsic activity, Molecular Conformation, CHO Cells, Crystallography, X-Ray, Partial agonist, Piperazines, Receptors, Dopamine, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, Dopamine receptor D3, Cricetinae, Drug Discovery, Animals, Humans, Receptor, Saimiri, 5-HT receptor, Molecular Structure, Receptors, Dopamine D2, Chemistry, Receptors, Dopamine D3, Recombinant Proteins, Rats, Pyrimidines, Biochemistry, Dopamine receptor, Receptors, Serotonin, Molecular Medicine, Serotonin, Endogenous agonist

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a87db13947cb7fb22fb6f9cfb72e85f
https://doi.org/10.1021/jm9707378

المؤلفون: Lawrence D. Wise, A E Corbin, Jon Wright, Hyacinth C. Akunne, Thomas G. Heffner, Lynn M. Georgic, Kim T. Zoski, Steven Z. Whetzel, Thomas A. Pugsley, C.B. Nelson

المصدر: Pharmacology Biochemistry and Behavior. 59:487-493

مصطلحات موضوعية: Male, Clinical Biochemistry, CHO Cells, Motor Activity, Pharmacology, Biology, Toxicology, Biochemistry, Muscarinic agonist, Cholinergic Antagonists, Rats, Sprague-Dawley, Mice, Behavioral Neuroscience, chemistry.chemical_compound, Piperidines, Neurotransmitter receptor, Dopamine receptor D3, Dopamine, Cricetinae, Muscarinic acetylcholine receptor, medicine, Animals, Biogenic Monoamines, Neurotransmitter, Receptor, Biological Psychiatry, Brain Chemistry, Dose-Response Relationship, Drug, Receptors, Dopamine D3, Antagonist, Rats, Dopamine D2 Receptor Antagonists, chemistry, Dopamine Antagonists, Benzimidazoles, Antipsychotic Agents, Signal Transduction, Thymidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122fd00726408bd6c620552d0f4db4f4
https://doi.org/10.1016/s0091-3057(97)00442-5

المؤلفون: Haile Tecle, Y Pei, Thomas G. Heffner, James N. Wiley, Steven Z. Whetzel, F W Ninteman, Hyacinth C. Akunne, A E Corbin, Thomas A. Pugsley

المصدر: Neuropharmacology. 36:51-62

مصطلحات موضوعية: Male, medicine.medical_specialty, N-Methylaspartate, Pyridines, Guinea Pigs, Sigma receptor, Motor Activity, Pharmacology, Rats, Sprague-Dawley, Mice, Cellular and Molecular Neuroscience, Dopamine, Internal medicine, Muscarinic acetylcholine receptor, medicine, Animals, Receptors, sigma, Rats, Wistar, Receptor, Cyclic GMP, Cells, Cultured, Behavior, Animal, Chemistry, Dopaminergic, Brain, Biological activity, Isoxazoles, Ligand (biochemistry), Rats, Endocrinology, Haloperidol, NMDA receptor, Calcium, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ef049a8056f7144948526d90bd42fd
https://doi.org/10.1016/s0028-3908(96)00161-x

المؤلفون: Steven Z. Whetzel, Steven B. Demattos, Wayne L. Cody, T. A. Pugsley, Hyacinth C. Akunne, David J. Wustrow, Thomas G. Heffner, Duff M. Davis, Lawrence D. Wise

المصدر: Biochemical Pharmacology. 49:1147-1154

مصطلحات موضوعية: Agonist, G protein, medicine.drug_class, Molecular Sequence Data, Biology, Biochemistry, Calcium in biology, Cell Line, Mice, chemistry.chemical_compound, medicine, Animals, Humans, Receptors, Neurotensin, Amino Acid Sequence, Receptor, Cyclic GMP, Neurotensin, Brain Chemistry, Pharmacology, Phospholipase C, Cell Membrane, Molecular biology, Animals, Newborn, chemistry, Neuromedin N, Calcium, Oligopeptides, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747295cd6a77df55fe013077b8e6f582
https://doi.org/10.1016/0006-2952(95)98512-8

المؤلفون: Steven Z. Whetzel, Hyacinth C. Akunne, David Juergen Wustrow, Thomas G. Heffner, Lawrence D. Wise, Thomas A. Pugsley, A E Corbin, J.N. Wiley, S. Demattos

المصدر: Peptides. 16:37-44

مصطلحات موضوعية: Male, medicine.medical_specialty, Physiology, Dopamine, Hypothermia, Striatum, Biology, Biochemistry, Calcium in biology, Mice, Radioligand Assay, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Endocrinology, In vivo, Internal medicine, medicine, Animals, Humans, Neurotensin receptor, Receptor, Cyclic GMP, Cells, Cultured, Neurotensin, Brain Chemistry, Psychotropic Drugs, Membranes, Carcinoma, Antagonist, Rats, chemistry, Colonic Neoplasms, Quinolines, Pyrazoles, Calcium, Oligopeptides, Locomotion, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c1d7518c0a32baebea00db225515fb
https://doi.org/10.1016/0196-9781(94)00146-w

المؤلفون: Yu Hsin Shih, David J. Wustrow, Thomas G. Heffner, Hyacinth Akunne, T. A. Pugsley, Don Van Leeuwen, Steven Z. Whetzel, Robert G. MacKenzie, Kim Zoski, Lawrence D. Wise

المصدر: Progress in neuro-psychopharmacologybiological psychiatry. 26(2)

مصطلحات موضوعية: Male, medicine.medical_specialty, Adrenergic receptor, CHO Cells, Pharmacology, Biology, Hippocampus, Piperazines, Mice, Catecholamines, Dopamine, Internal medicine, Cricetinae, medicine, Animals, Humans, Rats, Long-Evans, Receptor, Biological Psychiatry, Mice, Knockout, Dose-Response Relationship, Drug, Receptors, Dopamine D2, Receptors, Dopamine D4, Rats, Dopamine D2 Receptor Antagonists, Endocrinology, Mechanism of action, Dopamine receptor, Catecholamine, Dopamine Antagonists, Benzimidazoles, Serotonin, medicine.symptom, Receptor antagonist activity, medicine.drug, Benzyl Alcohol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9ef402e212e1904f36cb6746841520
https://pubmed.ncbi.nlm.nih.gov/11817497

المؤلفون: Hyacinth Akunne, R.M Brandon, J.J Cordon, Steven Z. Whetzel, T. A. Pugsley, F Roman, Kim Zoski

المصدر: Neuropharmacology. 41(1)

مصطلحات موضوعية: Cyclopropanes, Male, medicine.medical_specialty, Tyrosine 3-Monooxygenase, Sigma receptor, Pharmacology, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, Igmesine, Radioligand Assay, Idazoxan, Desipramine, Internal medicine, Receptors, Adrenergic, beta, medicine, Cyclic AMP, Animals, Receptors, sigma, Biogenic Monoamines, Monoamine Oxidase, Chromatography, High Pressure Liquid, Brain Chemistry, Neurons, Chemistry, Antidepressive Agents, Rats, Monoamine neurotransmitter, Endocrinology, Mechanism of action, Receptors, GABA-B, Cinnamates, Receptors, Serotonin, Antidepressant, NMDA receptor, Serotonin, medicine.symptom, Adrenergic alpha-Agonists, Receptors, Serotonin, 5-HT1, medicine.drug, Synaptosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9a315ea3524072fdd408a2273e597e
https://pubmed.ncbi.nlm.nih.gov/11445194

المؤلفون: Lynn M. Georgic, Wouter A. Brink, Lawrence D. Wise, Thomas G. Heffner, Yu-Hsin Shih, David Juergen Wustrow, Hyacinth C. Akunne, Steven Z. Whetzel, A E Corbin, Kim T. Zoski, Thomas A. Pugsley, Thomas R. Belliotti

المصدر: Journal of medicinal chemistry. 42(25)

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, medicine.drug_class, medicine.medical_treatment, Dopamine, Atypical antipsychotic, CHO Cells, Pharmacology, Hippocampus, Neurochemical, Oral administration, Cricetinae, Drug Discovery, Oxazines, medicine, Animals, Antipsychotic, Mass screening, Benzoxazinones, Chemistry, Receptors, Dopamine D4, Antagonist, Corpus Striatum, Rats, Dopamine D2 Receptor Antagonists, Molecular Medicine, 3,4-Dihydroxyphenylacetic Acid, Dopamine Antagonists, medicine.drug, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f07ba517770a48473c07f1e3ab4ecb2
https://pubmed.ncbi.nlm.nih.gov/10602703

المؤلفون: J. R. Rubin, Lawrence D. Wise, A E Corbin, David Juergen Wustrow, Thomas G. Heffner, Kim T. Zoski, Steven Z. Whetzel, Suzanne R. Kesten, Thomas A. Pugsley, Wouter A. Brink, Thomas R. Belliotti

المصدر: Bioorganicmedicinal chemistry letters. 8(12)

مصطلحات موضوعية: Indoles, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Stereoisomerism, Motor Activity, Biochemistry, Chemical synthesis, Structure-Activity Relationship, X-Ray Diffraction, Dopamine, Drug Discovery, medicine, Moiety, Structure–activity relationship, Animals, Receptor, Molecular Biology, Chemistry, Receptors, Dopamine D2, Organic Chemistry, Receptors, Dopamine D4, Ligand (biochemistry), Rats, Receptors, Serotonin, Molecular Medicine, Enantiomer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e9fbde4ab5519c7afc4398af54ad88
https://pubmed.ncbi.nlm.nih.gov/9873377

المؤلفون: Steven Z. Whetzel, David J. Dooley, Thomas A. Pugsley

المصدر: Psychopharmacology. 137(1)

مصطلحات موضوعية: Male, Cyclohexanecarboxylic Acids, medicine.medical_treatment, Dopamine, Striatum, Pharmacology, Hippocampal formation, Acetates, 5-Hydroxytryptophan, Rats, Sprague-Dawley, chemistry.chemical_compound, Biogenic amine, medicine, Premovement neuronal activity, Animals, Biogenic Monoamines, 4-Aminopyridine, Amines, Neurotransmitter, gamma-Aminobutyric Acid, chemistry.chemical_classification, Brain, Dihydroxyphenylalanine, Rats, Anticonvulsant, chemistry, Anticonvulsants, Serotonin, Amifampridine, Gabapentin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b8ac2d43963017f4f02508f04b9784
https://pubmed.ncbi.nlm.nih.gov/9631959

المؤلفون: Ann E. Corbin, David J. Wustrow, Lawrence D. Wise, William J. Smith, Thomas G. Heffner, M. Duff Davis, T. A. Pugsley, Steven Z. Whetzel, Lynn M. Georgic

المصدر: Journal of medicinal chemistry. 40(2)

مصطلحات موضوعية: Agonist, Male, Indoles, Tertiary amine, medicine.drug_class, Stereochemistry, Pyridines, CHO Cells, Chemical synthesis, Partial agonist, Piperazines, Rats, Sprague-Dawley, Mice, Dopamine, Cyclohexanes, Dopamine receptor D2, Cricetinae, Drug Discovery, medicine, Animals, Humans, Saimiri, Autoreceptors, Indole test, Behavior, Animal, Chemistry, Receptors, Dopamine D2, Rats, Kinetics, Dopamine Agonists, Autoreceptor, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fba5abd973c28c3cbefaf2398ab01f
https://pubmed.ncbi.nlm.nih.gov/9003524

المؤلفون: Theodore L. Hopkins, Steven Z. Whetzel, Yoichi Aso, Karl J. Kramer

المصدر: Insect Biochemistry. 14:463-472

مصطلحات موضوعية: biology, Decarboxylation, Tyrosinase, Cuticle, Tyramine, biology.organism_classification, Biochemistry, Quinone, Hydroxylation, chemistry.chemical_compound, chemistry, Manduca sexta, Insect Science, Tyrosine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e8845f1e9c8c25370f9e3aa622c065a9
https://doi.org/10.1016/0020-1790(84)90103-3