المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Brigatinib_and_dasatinib_synergized_to_reduce_i_NF2_i_-deficient_Schwann_cell_viability_/14990631

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s003

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Single_and_combination_drug_treatment_of_meningioma-related_cell_lines_/14990628

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s002

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Cell_survival_responses_to_all_MIPE_4_0_library_agents_as_judged_by_relative_AUCs_binned_per_mechanistic_classes_with_mechanistic_superclasses_listed_in_order_from_top_to_bottom_Transcriptional_regulation_physiological_homeostasis_other_met/14990625

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s001

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Relative_tumor_sizes_in_meningioma-bearing_mice_prior_to_or_after_treatment_with_MK-2206_and_brigatinib_either_alone_or_in_combination_for_12_weeks_/14990667

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s012

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/ALK_was_not_detected_in_normal_meningeal_and_meningioma_cells_with_or_without_i_NF2_i_expression_/14990649

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s007

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Gene_expression_changes_caused_by_drug_treatments_/14990640

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s005

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Dasatinib_and_simvastatin_synergized_to_reduce_the_viability_of_Schwann_and_schwannoma_cells_/14990637

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s004

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/MIB_MS_kinome_profiling_reveals_dasatinib_and_brigatinib_target_specificity_/14990646

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s006

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Inhibition_of_multiple_RTKs_and_non-RTKs_in_Ben-Men-1_cells_treated_with_1x_IC_sub_50_sub_of_brigatinib_under_various_growth_conditions_/14990652

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s008

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Ben-Men-1_cells_expressed_low_levels_of_p-EGFR_which_was_abolished_by_brigatinib_treatment_/14990655

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s009

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Brigatinib_inhibited_p-FAK_p-AKT_and_p-S6_target_pathways_in_i_Postn-Cre_Nf2_i_sup_i_flox_flox_i_sup_mice_/14990670

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s013

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Mouse_PK_parameters_following_a_single_oral_dose_of_brigatinib_or_MK-2206_at_the_MTD_/14990664

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s011

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/Supporting_information_methods_/14991503

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s021

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/14991509

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s022

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/dataset/Fold-change_and_significance_of_differential_expression_in_treated_and_untreated_cells_/14990673

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s014

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/dataset/Pathways_enriched_for_differentially_expressed_genes_/14990676

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s015

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/dataset/Kinome_data_plotted_in_Fig_3A_3D_/14991479

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s016

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/dataset/Kinome_data_plotted_in_Fig_3E_/14991485

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s017

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/dataset/Kinome_data_plotted_in_Figs_3F_and_S6A_/14991488

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s018

المؤلفون: Long-Sheng Chang (41691), Janet L. Oblinger (11141313), Abbi E. Smith (11141316), Marc Ferrer (191300), Steven P. Angus (5536277), Eric Hawley (8813501), Alejandra M. Petrilli (5390945), Roberta L. Beauchamp (11141319), Lars Björn Riecken (11141322), Serkan Erdin (39633), Ming Poi (7882559), Jie Huang (104235), Waylan K. Bessler (11141325), Xiaohu Zhang (391063), Rajarshi Guha (182356), Craig Thomas (288536), Sarah S. Burns (5390951), Thomas S. K. Gilbert (4029056), Li Jiang (120930), Xiaohong Li (71964), Qingbo Lu (9603569), Jin Yuan (120922), Yongzheng He (120908), Shelley A. H. Dixon (11141328), Andrea Masters (11141331), David R. Jones (242367), Charles W. Yates (5390939), Stephen J. Haggarty (201464), Salvatore La Rosa (6710648), D. Bradley Welling (5390942), Anat O. Stemmer-Rachamimov (2327947), Scott R. Plotkin (10067078), James F. Gusella (8139939), Justin Guinney (215130), Helen Morrison (781686), Vijaya Ramesh (804307), Cristina Fernandez-Valle (5390930), Gary L. Johnson (363110), Jaishri O. Blakeley (5390933), D. Wade Clapp (11141334)

مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, ALK Neurofibromatosis Type 2, FDA, NF 2 schwannomas, NF 2, adhesion kinase 1, NF 2 tumor suppressor gene, tyrosine kinases, NF 2-deficient meningioma, ALUNBRIG, FAK, Brigatinib causes tumor shrinkage

Relation: https://figshare.com/articles/dataset/Kinome_data_plotted_in_Figs_3H_and_S6B_/14991500

الاتاحة: https://doi.org/10.1371/journal.pone.0252048.s020