المؤلفون: Stepniewski, Tomasz Maciej

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Selent, Jana

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: G protein-coupled receptor, Neurotransmission, Pharmacology, Molecular dynamics, Bioinformatics, Receptores acoplados a proteína G, Neurotransmisión, Farmacología, Dinámicas moleculares, Bioinformática

Time: 616.8

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/668308

المؤلفون: Kossatz de Mello, Elk, 1977-, Diez Alarcia, Rebeca, Gaitonde, Supriya A., Ramon Duaso, Carla, 1987-, Stepniewski, Tomasz Maciej, 1988-, Aranda García, David, Muneta Arrate, Itziar, Tepaz, Elodie, Saen-Oon, Suwipa, Soliva, Robert, Shahraki, Aida, Moreira, David, Brea, José, Loza, María I., Torre Fornell, Rafael de la, Kolb, Peter, Bouvier, Michel, Meana, J. Javier, Robledo, Patricia, 1958-, Selent, Jana

مصطلحات موضوعية: Computational biophysics, G protein-coupled receptors, Schizophrenia, Target validation

وصف الملف: application/pdf

Relation: Nat Commun. 2024 May 29;15(1):4307; info:eu-repo/grantAgreement/EC/H2020/823830; info:eu-repo/grantAgreement/ES/2PE/PID2020-119428RB-I00; info:eu-repo/grantAgreement/ES/2PE/SAF2017-88126-R; http://hdl.handle.net/10230/60760

الاتاحة: http://hdl.handle.net/10230/60760
https://doi.org/10.1038/s41467-024-48196-2

المؤلفون: Lopez‐Balastegui, Marta, Stepniewski, Tomasz Maciej, Kogut‐Günthel, Małgorzata M., Di Pizio, Antonella, Rosenkilde, Mette Marie, Mao, Jiafei, Selent, Jana

المساهمون: Instituto de Salud Carlos III

المصدر: British Journal of Pharmacology ; ISSN 0007-1188 1476-5381

الاتاحة: http://dx.doi.org/10.1111/bph.16495
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bph.16495

المؤلفون: Gasbjerg, Lærke Smidt, Rasmussen, Rasmus Syberg, Dragan, Adrian, Lindquist, Peter, Melchiorsen, Josefine Ulrikke, Stepniewski, Tomasz Maciej, Schiellerup, Sine, Tordrup, Esther Karen, Gadgaard, Sarina, Kizilkaya, Hüsün Sheyma, Willems, Sabine, Zhong, Yi, Wang, Yi, Wright, Shane C., Lauschke, Volker M., Hartmann, Bolette, Holst, Jens Juul, Selent, Jana, Rosenkilde, Mette Marie

المساهمون: Novo Nordisk Fonden, Kirsten og Freddy Johansens Fond, Deutsche Forschungsgemeinschaft, Svenska Sällskapet för Medicinsk Forskning, Vetenskapsrådet, Robert Bosch Stiftung

المصدر: British Journal of Pharmacology ; ISSN 0007-1188 1476-5381

الاتاحة: http://dx.doi.org/10.1111/bph.16478
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bph.16478

المؤلفون: Stepniewski, Tomasz Maciej, Mancini, Arturo, Ågren, Richard, Torrens-Fontanals, Mariona, Semache, Meriem, Bouvier, Michel, Sahlholm, Kristoffer, Breton, Billy, Selent, Jana

المصدر: Chemical Science. 12(33):10990-11003

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187333
https://doi.org/10.1039/d1sc00749a
https://umu.diva-portal.org/smash/get/diva2:1592304/FULLTEXT01.pdf

المؤلفون: Zieniuk, Bartlomiej, Stepniewski, Tomasz Maciej, 1988-, Fabiszewska, Agata

مصطلحات موضوعية: 3-Phenylpropionic acid, C. antarctica lipase B, Cinnamic acid, Enzyme substrate specificity, Esterification, Molecular dynamics, Novozym 435

وصف الملف: application/pdf

Relation: Arch Biochem Biophys. 2023 Dec;750:109807; http://hdl.handle.net/10230/61275; http://dx.doi.org/10.1016/j.abb.2023.109807

الاتاحة: http://hdl.handle.net/10230/61275
https://doi.org/10.1016/j.abb.2023.109807

المؤلفون: Kjaer, Viktoria Madeline Skovgaard, Stepniewski, Tomasz Maciej, 1988-, Medel Lacruz, Brian, Reinmuth, Lisa, Ciba, Marija, Rexen Ulven, Elisabeth, Bonomi, Massimiliano, Selent, Jana, Rosenkilde, Mette Marie

مصطلحات موضوعية: Dinàmica molecular, Proteïnes G

وصف الملف: application/pdf

Relation: Chem Sci. 2023 Sep 25;14(39):10671-83; http://hdl.handle.net/10230/59964; http://dx.doi.org/10.1039/d2sc05962b

الاتاحة: http://hdl.handle.net/10230/59964
https://doi.org/10.1039/d2sc05962b

المؤلفون: Grimes, Jak, Koszegi, Zsombor, Lanoiselée, Yann, Miljus, Tamara, O'Brien, Shannon L., Stepniewski, Tomasz Maciej, 1988-, Medel Lacruz, Brian, Baidya, Mithu, Makarova, Maria, Mistry, Ravi, Goulding, Joëlle, Drube, Julia, Hoffmann, Carsten, Owen, Dylan M., Shukla, Arun K., Selent, Jana, Hill, Stephen J., Calebiro, Davide

مصطلحات موضوعية: G protein-coupled receptors, GPCR, TIRF, Arrestin, Plasma membrane, Protein-protein interactions, Single-molecule microscopy

وصف الملف: application/pdf

Relation: Cell. 2023;186(10):2238-55; http://hdl.handle.net/10230/57839; http://dx.doi.org/10.1016/j.cell.2023.04.018

الاتاحة: http://hdl.handle.net/10230/57839
https://doi.org/10.1016/j.cell.2023.04.018

المؤلفون: Eiger, Dylan S., Smith, Jeffrey S., Shi, Tujin, Stepniewski, Tomasz Maciej, Tsai, Chia-Feng, Honeycutt, Christopher, Boldizsar, Noelia, Gardner, Julia, Nicora, Carrie D., Moghieb, Ahmed M., Kawakami, Kouki, Choi, Issac, Hicks, Chloe, Zheng, Kevin, Warman, Anmol, Alagesan, Priya, Knape, Nicole M., Huang, Ouwen, Silverman, Justin D., Smith, Richard D., Inoue, Asuka, Selent, Jana, Jacobs, Jon M., Rajagopal, Sudarshan

المصدر: Cell Chemical Biology ; volume 30, issue 4, page 362-382.e8 ; ISSN 2451-9456

الاتاحة: http://dx.doi.org/10.1016/j.chembiol.2023.03.006
https://api.elsevier.com/content/article/PII:S2451945623000855?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2451945623000855?httpAccept=text/plain

المؤلفون: Agren, Richard, Zeberg, Hugo, Stepniewski, Tomasz Maciej, Free, R. Benjamin, Reilly, Sean W., Luedtke, Robert R., Arhem, Peter, Ciruela, Francisco, Sibley, David R., Mach, Robert H., Selent, Jana, Nilsson, Johanna, Sahlholm, Kristoffer

المصدر: ACS Chemical Neuroscience

مصطلحات موضوعية: HEK cells, PET scan, Xenopus oocytes, antipsychotics, arrestin, competitive binding, drug kinetics, molecular dynamics simulation, Dopamine D2 Receptor Antagonists / pharmacology, Dopamine, GTP-Binding Proteins / metabolism, Ligands, Receptors, Dopamine D2 / genetics, Dopamine D2 / metabolism

وصف الملف: application/pdf

Relation: https://doi.org/10.1021/acschemneuro.0c00477; Ågren, R., Zeberg, H., St?pniewski, T. M., Free, R. B., Reilly, S. W., Luedtke, R. R., Århem, P., Ciruela, F., Sibley, D. R., Mach, R. H., Selent, J., Nilsson, J., & Sahlholm, K. (2020). Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism. ACS chemical neuroscience, 11(19), 3130-3143. https://doi.org/10.1021/acschemneuro.0c00477; https://hdl.handle.net/20.500.12503/31865; 11; 19

الاتاحة: https://hdl.handle.net/20.500.12503/31865

المؤلفون: Krajewska, Joanna, Nowicki, Krzysztof, Durka, Krzysztof, Marek-Urban, Paulina H., Wińska, Patrycja, Stepniewski, Tomasz Maciej, 1988-, Woźniak, Krzysztof, Laudy, Agnieszka E., Luliński, Sergiusz

وصف الملف: application/pdf

Relation: RSC Adv. 2022 Aug 16;12(36):23099-117; info:eu-repo/grantAgreement/EC/H2020/730897; http://hdl.handle.net/10230/55752; http://dx.doi.org/10.1039/d2ra03910a

الاتاحة: http://hdl.handle.net/10230/55752
https://doi.org/10.1039/d2ra03910a

المؤلفون: Baidya, Mithu, Chaturvedi, Madhu, Dwivedi, Hemlata, Ranjan, Ashutosh, Devost, Dominic, Namkung, Yoon, Stepniewski, Tomasz Maciej, 1988-, Pandey, Shubhi, Baruah, Minakshi, Panigrahi, Bhanupriya, Sarma, Parishmita, Yadav, Manish K., Maharana, Jagannath, Banerjee, Ramanuj, Kawakami, Kouki, Inoue, Asuka, Selent, Jana, Laporte, Stéphane A., Hébert, Terence E., Shukla, Arun K.

مصطلحات موضوعية: G protein-coupled receptors, Hormone receptors

وصف الملف: application/pdf

Relation: Nat Commun. 2022 Aug 8;13(1):4634; http://hdl.handle.net/10230/55671

الاتاحة: http://hdl.handle.net/10230/55671
https://doi.org/10.1038/s41467-022-32386-x

المؤلفون: Ågren, Richard, Stepniewski, Tomasz Maciej, Zeberg, Hugo, Selent, Jana, Sahlholm, Kristoffer

المصدر: International Journal of Molecular Sciences. 22(8)

مصطلحات موضوعية: Aminotetralins, Electrophysiology, G protein-coupled receptor, Molecular dynamics simulation, Phenethylamines, Voltage-clamp, Xenopus oocytes

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-182576
https://doi.org/10.3390/ijms22084078
https://umu.diva-portal.org/smash/get/diva2:1553534/FULLTEXT01.pdf

المؤلفون: Gareri, Clarice, Pfeiffer, Conrad T., Jiang, Xue, Paulo, Joao A., Gygi, Steven P., Pham, Uyen, Chundi, Anand, Wingler, Laura M., Staus, Dean P., Stepniewski, Tomasz Maciej, Selent, Jana, Lucero, Emilio Y., Grogan, Alyssa, Rajagopal, Sudarshan, Rockman, Howard A.

المصدر: Science Signaling; 8/13/2024, Vol. 17 Issue 849, p1-16, 16p

مصطلحات موضوعية: G proteins, ANGIOTENSIN II, MOLECULAR dynamics, LIGANDS (Biochemistry), G protein coupled receptors, PHOSPHORYLATION

المؤلفون: Peralta-Garcia, Alejandro, Torrens Fontanals, Mariona, Stepniewski, Tomasz Maciej, 1988-, Grau-Expósito, Judith, Perea, David, Ayinampudi, Vikram, Waldhoer, Maria, Zimmermann, Mirjam, Buzón, María J., Genescà, Meritxell, Selent, Jana

مصطلحات موضوعية: COVID-19, SARS-CoV-2, Drug repurposing, Viral cell entry assays, Virtual screening

وصف الملف: application/pdf

Relation: Int J Mol Sci. 2021;22(24):13592; http://hdl.handle.net/10230/52352; http://dx.doi.org/10.3390/ijms222413592

الاتاحة: http://hdl.handle.net/10230/52352
https://doi.org/10.3390/ijms222413592

المؤلفون: Kumar, G Aditya, Sarkar, Parijat, Stepniewski, Tomasz Maciej, 1988-, Jafurulla, Md, Singh, Shishu Pal, Selent, Jana, Chattopadhyay, Amitabha

وصف الملف: application/pdf

Relation: Sci Adv. 2021;7(30):eabh2922; Kumar GA, Sarkar P, Stepniewski TM, Jafurulla M, Singh SP, Selent J, Chattopadhyay A. A molecular sensor for cholesterol in the human serotonin 1A receptor. Sci Adv. 2021;7(30):eabh2922. DOI:10.1126/sciadv.abh2922; http://hdl.handle.net/10230/48590; http://dx.doi.org/10.1126/sciadv.abh2922

الاتاحة: http://hdl.handle.net/10230/48590
https://doi.org/10.1126/sciadv.abh2922

المؤلفون: Giubilaro, Jenna, Schuetz, Doris A., Stepniewski, Tomasz Maciej, 1988-, Namkung, Yoon, Khoury, Etienne, Lara Márquez, Mónica, Campbell, Shirley, Beautrait, Alexandre, Armando, Sylvain, Radresa, Olivier, Duchaine, Jean, Lamarche Vane, Nathalie, Claing, Audrey, Selent, Jana, Bouvier, Michel, Marinier, Anne, Laporte, Stéphane A.

مصطلحات موضوعية: Hormone receptors, Screening

وصف الملف: application/pdf

Relation: Nat Commun. 2021;12(1):4688; http://hdl.handle.net/10230/48573

الاتاحة: http://hdl.handle.net/10230/48573
https://doi.org/10.1038/s41467-021-24968-y

المؤلفون: Rodríguez-Espigares, Ismael, Torrens-Fontanals, Mariona, Tiemann, Johanna K. S., Aranda-García, David, Ramírez-Anguita, Juan Manuel, Stepniewski, Tomasz Maciej, Worp, Nathalie, Varela-Rial, Alejandro, Morales-Pastor, Adrián, Medel-Lacruz, Brian, Pándy-Szekeres, Gáspár, Mayol, Eduardo, Giorgino, Toni, Carlsson, Jens, Deupi, Xavier, Filipek, Slawomir, Filizola, Marta, Gómez-Tamayo, José Carlos, Gonzalez, Angel, Gutiérrez-de-Terán, Hugo, Jiménez-Rosés, Mireia, Jespers, Willem, Kapla, Jon, Khelashvili, George, Kolb, Peter, Latek, Dorota, Marti-Solano, Maria, Matricon, Pierre, Matsoukas, Minos Timotheos, Miszta, Przemyslaw, Olivella, Mireia, Perez-Benito, Laura, Provasi, Davide, Ríos, Santiago, Torrecillas, Iván R., Sallander, Jessica, Sztyler, Agnieszka, Vasile, Silvana, Weinstein, Harel, Zachariae, Ulrich, Hildebrand, Peter W., De Fabritiis, Gianni, Sanz, Ferran, Gloriam, David E., Cordomi, Arnau, Guixà-González, Ramon, Selent, Jana

المصدر: Rodríguez-Espigares , I , Torrens-Fontanals , M , Tiemann , J K S , Aranda-García , D , Ramírez-Anguita , J M , Stepniewski , T M , Worp , N , Varela-Rial , A , Morales-Pastor , A , Medel-Lacruz , B , Pándy-Szekeres , G , Mayol , E , Giorgino , T , Carlsson , J , Deupi , X , Filipek , S , Filizola , M , Gómez-Tamayo , J C , Gonzalez , A , Gutiérrez-de-Terán , H , Jiménez-Rosés , M , Jespers , W , Kapla , J , Khelashvili , ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1300/1305, name=Biotechnology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

Relation: https://discovery.dundee.ac.uk/en/publications/4e1f122d-3182-481e-a52f-4c7891fcec11

الاتاحة: https://discovery.dundee.ac.uk/en/publications/4e1f122d-3182-481e-a52f-4c7891fcec11
https://doi.org/10.1038/s41592-020-0928-3
http://www.scopus.com/inward/record.url?scp=85088652693&partnerID=8YFLogxK

المؤلفون: Rodríguez-Espigares, Ismael, Torrens-Fontanals, Mariona, Tiemann, Johanna K. S., Aranda-García, David, Ramírez-Anguita, Juan Manuel, Stepniewski, Tomasz Maciej, Worp, Nathalie, Varela-Rial, Alejandro, Morales-Pastor, Adrián, Medel-Lacruz, Brian, Pándy-Szekeres, Gáspár, Mayol, Eduardo, Giorgino, Toni, Carlsson, Jens, Deupi, Xavier, Filipek, Slawomir, Filizola, Marta, Gómez-Tamayo, José Carlos, Gonzalez, Angel, Gutiérrez-de-Terán, Hugo, Jiménez-Rosés, Mireia, Jespers, Willem, Kapla, Jon, Khelashvili, George, Kolb, Peter, Latek, Dorota, Marti-Solano, Maria, Matricon, Pierre, Matsoukas, Minos Timotheos, Miszta, Przemyslaw, Olivella, Mireia, Perez-Benito, Laura, Provasi, Davide, Ríos, Santiago, Torrecillas, Iván R., Sallander, Jessica, Sztyler, Agnieszka, Vasile, Silvana, Weinstein, Harel, Zachariae, Ulrich, Hildebrand, Peter W., De Fabritiis, Gianni, Sanz, Ferran, Gloriam, David E., Cordomi, Arnau, Guixà-González, Ramon, Selent, Jana

المصدر: Rodríguez-Espigares , I , Torrens-Fontanals , M , Tiemann , J K S , Aranda-García , D , Ramírez-Anguita , J M , Stepniewski , T M , Worp , N , Varela-Rial , A , Morales-Pastor , A , Medel-Lacruz , B , Pándy-Szekeres , G , Mayol , E , Giorgino , T , Carlsson , J , Deupi , X , Filipek , S , Filizola , M , Gómez-Tamayo , J C , Gonzalez , A , Gutiérrez-de-Terán , H , Jiménez-Rosés , M , Jespers , W , Kapla , J , Khelashvili , ....

مصطلحات موضوعية: Cell signalling, Membrane biophysics, Protein databases, /dk/atira/pure/subjectarea/asjc/1300/1305, name=Biotechnology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/4642dfa4-f4d8-4b70-92a9-888a8543df87

الاتاحة: https://discovery.dundee.ac.uk/en/publications/4642dfa4-f4d8-4b70-92a9-888a8543df87
https://doi.org/10.1038/s41592-020-0884-y
https://discovery.dundee.ac.uk/ws/files/49547242/49491_2_merged_1590582664_1.pdf
http://www.scopus.com/inward/record.url?scp=85087806297&partnerID=8YFLogxK

المؤلفون: Ågren, Richard, Zeberg, Hugo, Stępniewski, Tomasz Maciej, Free, R. Benjamin, Reilly, Sean W., Luedtke, Robert R., Arhem, Peter, Ciruela, Francisco, Sibley, David R., Mach, Robert H., Selent, Jana, Nilsson, Johanna, Sahlholm, Kristoffer

مصطلحات موضوعية: drug kinetics, competitive binding, antipsychotics, PET scan, molecular dynamics simulation, Xenopus oocytes, arrestin, HEK cells, Neurosciences, Neurovetenskaper

وصف الملف: application/pdf

Relation: ACS Chemical Neuroscience, 2020, 11:19, s. 3130-3143; orcid:0000-0001-7118-1249; orcid:0000-0002-0624-962X; orcid:0000-0001-6536-1972; http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177063; PMID 32865974; ISI:000580513100022; Scopus 2-s2.0-85092680810

الاتاحة: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177063
https://doi.org/10.1021/acschemneuro.0c00477