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المؤلفون: Robert F. Bruns, Qi Chen, Paloma Vidal, John Mehnert Schaus, Charles R. Yang, Stephen N. Mitchell, Steven Marc Massey, Nuria Diaz, Xushan Wang, David Andrew Coates, Rebecca A. Wright, Beverly A. Heinz, Kevin Matthew Gardinier, Greg Stephenson, James P. Beck, Rajni M. Bhardwaj, Julie F. Falcone, Bruce A. Dressman, Deanna L Maren, Anette M. Johansson, David Michael Remick, Jeff W. Cramer, Cohen Michael Philip, Brian Morgan Watson, Jeffery Richardson, Kjell Svensson, Xin Zhou, Erik James Hembre, Serge Louis Boulet, Reinhard Matthew Robert, Daniel S. Richards, Junliang Hao, David M. Bender, Guy Carter, Christopher David Beadle, Brian G. Getman, Wolfangel Craig Daniel, Diseroad Benjamin Alan, Jason K. Myers, Joseph H. Krushinski, David Edward Tupper
المصدر: Journal of Medicinal Chemistry. 62:8711-8732
مصطلحات موضوعية: 0303 health sciences, Catechol, Allosteric modulator, Stereochemistry, Subtype selective, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Dopamine receptor D1, chemistry, Dopamine, Drug Discovery, medicine, Molecular Medicine, Hydroxymethyl, 030304 developmental biology, medicine.drug
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المؤلفون: Junliang, Hao, James P, Beck, John M, Schaus, Joseph H, Krushinski, Qi, Chen, Christopher D, Beadle, Paloma, Vidal, Matthew R, Reinhard, Bruce A, Dressman, Steven M, Massey, Serge L, Boulet, Michael P, Cohen, Brian M, Watson, David, Tupper, Kevin M, Gardinier, Jason, Myers, Anette M, Johansson, Jeffery, Richardson, Daniel S, Richards, Erik J, Hembre, David M, Remick, David A, Coates, Rajni M, Bhardwaj, Benjamin A, Diseroad, David, Bender, Greg, Stephenson, Craig D, Wolfangel, Nuria, Diaz, Brian G, Getman, Xu-Shan, Wang, Beverly A, Heinz, Jeff W, Cramer, Xin, Zhou, Deanna L, Maren, Julie F, Falcone, Rebecca A, Wright, Stephen N, Mitchell, Guy, Carter, Charles R, Yang, Robert F, Bruns, Kjell A, Svensson
المصدر: Journal of medicinal chemistry. 62(19)
مصطلحات موضوعية: Binding Sites, Receptors, Dopamine D1, Molecular Conformation, Administration, Oral, Crystallography, X-Ray, Isoquinolines, Kidney, Acetylcholine, Rats, Small Molecule Libraries, Mice, Structure-Activity Relationship, HEK293 Cells, Allosteric Regulation, Cyclic AMP, Animals, Humans, Protein Isoforms, Locomotion, Half-Life
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المؤلفون: Wesley H. Anderson, Paul L. Ornstein, Vladamir Tolstikov, Guy Carter, Renhua Li, Brian J. Eastwood, Carl D Overshiner, Alexander Nikolayev, Kurt Rasmussen, Stephen Smith, Gary Gilmour, Stephen Swanson, Linda M. Rorick-Kehn, Xia Li, Keith A. Wafford, John T. Catlow, Jeffrey M. Witkin, Stephen N. Mitchell, Charles H. Mitch, Ming-Shang Kuo, Jennifer Li, James A. Monn
المصدر: Journal of Pharmacology and Experimental Therapeutics. 361:68-86
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, medicine.drug_class, Chemistry, Antagonist, Glutamate receptor, Receptor antagonist, Ventral tegmental area, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Metabotropic receptor, medicine.anatomical_structure, Dopamine, medicine, Molecular Medicine, Ketamine, Receptor, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: James A. Monn, Kurt Rasmussen, Guy Carter, Stephen N. Mitchell, Linda M. Rorick-Kehn, Jeffrey M. Witkin, Bryan G. Johnson, Xia Li, Darryle D. Schoepp, Carl D Overshiner
المصدر: Journal of Pharmacology and Experimental Therapeutics. 358:71-82
مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, medicine.drug_class, Dopamine, Microdialysis, Action Potentials, Prefrontal Cortex, AMPA receptor, Motor Activity, Pharmacology, Receptors, Metabotropic Glutamate, Nucleus Accumbens, 03 medical and health sciences, 0302 clinical medicine, Quinoxalines, Dopamine receptor D2, Animals, Medicine, Receptors, AMPA, Amino Acids, Rats, Wistar, Neurons, Mice, Inbred BALB C, Dose-Response Relationship, Drug, business.industry, Ventral Tegmental Area, Dopaminergic, Antidepressive Agents, Ventral tegmental area, 030104 developmental biology, medicine.anatomical_structure, Metabotropic receptor, Xanthenes, Molecular Medicine, Antidepressant, Ketamine, business, Excitatory Amino Acid Antagonists, Neuroscience, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Arjan Blokland, Sarah Hescham, Stephen N. Mitchell, Ali Jahanshahi, Trevor Sharp, Yasin Temel, Guy Carter, Judith Schweimer
المساهمون: Neurochirurgie, RS: MHeNs - R3 - Neuroscience, Psychiatrie & Neuropsychologie, Section Psychopharmacology, RS: FPN NPPP II, MUMC+: MA Med Staf Spec Neurochirurgie (9), University of St Andrews. School of Psychology and Neuroscience
المصدر: Brain Structure & Function, 221(8). Springer
Brain Structure & Functionمصطلحات موضوعية: Male, 0301 basic medicine, Fornix, Microdialysis, Histology, Deep brain stimulation, Short Communication, Neuroscience(all), medicine.medical_treatment, Fornix, Brain, Glutamic Acid, Stimulus (physiology), Hippocampal formation, RAT-BRAIN, Hippocampus, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Memory, Animals, Medicine, Neurotransmitter, Neurons, business.industry, General Neuroscience, Glutamate receptor, Acetylcholine, eye diseases, Rats, ALZHEIMERS-DISEASE, surgical procedures, operative, 030104 developmental biology, nervous system, chemistry, RC0321, sense organs, Anatomy, business, Proto-Oncogene Proteins c-fos, RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry, Neuroscience, 030217 neurology & neurosurgery, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Michelle M Menezes, Jeffrey M. Witkin, Kjell A. Svensson, Brian J. Eastwood, Eyassu Chernet, Michael J. O'Neill, Julie F. Falcone, Keith A. Wafford, Hong Wang, Linda K. Thompson, John W. Ryder, Stephen N. Mitchell, Junliang Hao, John Mehnert Schaus, Robert F. Bruns, Alex J. Harper, Meghane E. Masquelin, Deanna L Maren, Xia Li, Tracey K. Murray, Charles R. Yang, Elaine Shanks, Jason Katner, Linli Zhang, Guy Carter, James P. Beck, Patrick L. Love
المصدر: Neuropharmacology. 128
مصطلحات موضوعية: 0301 basic medicine, Agonist, Male, Parkinson's disease, Reserpine, medicine.drug_class, Dopamine Agents, Prefrontal Cortex, Mice, Transgenic, Pharmacology, Levodopa, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Dopamine receptor D1, Hypokinesia, Dopamine, medicine, Animals, Wakefulness, Maze Learning, Rivastigmine, Blinking, Receptors, Dopamine D1, Potentiator, medicine.disease, Isoquinolines, Macaca mulatta, Corpus Striatum, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Psychotic Disorders, medicine.symptom, Nervous System Diseases, Psychology, Sleep, 030217 neurology & neurosurgery, medicine.drug, Antipsychotic Agents
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المؤلفون: Jon K. Reel, Akihiko Kato, Gary Gilmour, Keith A. Wafford, Warren J. Porter, Jennifer Li, Brian J. Eastwood, Stephen N. Mitchell, Guy Carter, Scott D. Gleason, Wesley Seidel, Kevin Matthew Gardinier, Jeffrey M. Witkin, Andrew McCarthy
المصدر: Neuropharmacology. 126
مصطلحات موضوعية: 0301 basic medicine, Male, Microdialysis, Serotonin, Pyridones, medicine.medical_treatment, Conditioning, Classical, Prefrontal Cortex, AMPA receptor, Fructose, Pharmacology, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Neurochemical, Cognition, Topiramate, Nitriles, medicine, Animals, Fear conditioning, Benzothiazoles, Rats, Wistar, Neurotransmitter, Maze Learning, Behavior, Animal, Electroencephalography, Spontaneous alternation, Fear, Acetylcholine, 030104 developmental biology, Anticonvulsant, chemistry, Pyrazoles, Anticonvulsants, Calcium Channels, Sleep Stages, Psychology, Neuroscience, 030217 neurology & neurosurgery, Histamine
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المؤلفون: Pamela Ohman Strickland, Stephen N. Mitchell, Sarah Mueller-Steiner, Elizabeth Tarasewicz, Samnang Tep, Kathryn Hilton, Akash Datwani, Michael J. O'Neill, Manuel Buttini, Kalpana M. Merchant, Kavita Prasad, Eric K. Richfield
المصدر: European Journal of Neuroscience. 33:642-656
مصطلحات موضوعية: Tyrosine hydroxylase, Neurite, General Neuroscience, Transgene, Dopaminergic, Congenic, Endogeny, Biology, Cell biology, Ventral tegmental area, medicine.anatomical_structure, Organelle, medicine, Neuroscience
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المؤلفون: Carlos Montero, Lorna Hayhurst, Leslie Walton, Stephen N. Mitchell, Rosemarie Tomlinson, Louise Wallace, Graham Henry Timms, Jeremy Gilmore, Jeremy Findlay, Jane Cooper, John R. Boot, Richard J. Broadmore, Alicia Marcos, Ana B. Bueno
المصدر: Bioorganic & Medicinal Chemistry Letters. 17:3344-3348
مصطلحات موضوعية: Stereochemistry, Serotonin reuptake inhibitor, Guinea Pigs, Clinical Biochemistry, Pharmaceutical Science, Naphthalenes, Pharmacology, Biochemistry, Piperazines, Structure-Activity Relationship, Drug Discovery, Animals, Structure–activity relationship, Serotonin Antagonists, Serotonin Uptake Inhibitors, Receptor, Molecular Biology, 5-HT receptor, Dose-Response Relationship, Drug, Chemistry, Organic Chemistry, Antagonist, Stereoisomerism, Antidepressive Agents, Kinetics, Models, Chemical, Receptor, Serotonin, 5-HT1D, Molecular Medicine, Reuptake inhibitor, Selective Serotonin Reuptake Inhibitors
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المؤلفون: K Diker, Graham Henry Timms, Chad Nolan Wolfe, John Joseph Masters, Simon James Richards, Serge Louis Boulet, Harris, Manuel Javier Cases-Thomas, Peter Thaddeus Gallagher, Jeremy Gilmore, Jeremy Findlay, Maria Ann Whatton, L. Delhaye, Virginia Ann Wood, Barry Peter Clark, M Naik, SM Smith, John Fairhurst, Robin G. Simmonds, Boot, Stephen N. Mitchell
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:2714-2718
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Chemical synthesis, Reuptake, Norepinephrine (medication), Norepinephrine, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Drug Discovery, medicine, Neurotransmitter, Molecular Biology, biology, Organic Chemistry, chemistry, Norepinephrine transporter, biology.protein, Catecholamine, Molecular Medicine, lipids (amino acids, peptides, and proteins), Serotonin, Reuptake inhibitor, Selective Serotonin Reuptake Inhibitors, medicine.drug
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المؤلفون: Susan Duty, Stephen N. Mitchell, Michael J. O'Neill, Naomi P. Visanji
المصدر: Neuropharmacology. 50:36-46
مصطلحات موضوعية: Male, Nicotine, Dopamine, Microdialysis, Substantia nigra, Receptors, Nicotinic, Pharmacology, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, medicine, Animals, Nicotinic Agonists, RNA, Messenger, Oxidopamine, In Situ Hybridization, Acetylcholine receptor, Pars compacta, Chemistry, Sympathectomy, Chemical, Rats, Substantia Nigra, Nicotinic acetylcholine receptor, Nicotinic agonist, Sympatholytics, Systemic administration, Autoradiography, medicine.drug
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12
المؤلفون: RG Simmonds, Boot, Peter Thaddeus Gallagher, Simon James Richards, Louise Wallace, G Brace, Stephen N. Mitchell, Jeremy Findlay, Nancy Dezutter, S Mahadevan, I Hoes, CL Delatour, John Fairhurst, Richard E. Rathmell, Maria Ann Whatton
المصدر: Bioorganic & Medicinal Chemistry Letters. 14:5395-5399
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Nerve Tissue Proteins, Thiophenes, In Vitro Techniques, Pharmacology, Biochemistry, Reuptake, Norepinephrine (medication), Norepinephrine, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Propylamines, Neurotransmitter, Molecular Biology, Serotonin Plasma Membrane Transport Proteins, Dopamine Plasma Membrane Transport Proteins, Membrane Glycoproteins, Norepinephrine Plasma Membrane Transport Proteins, Adrenergic Uptake Inhibitors, Symporters, biology, Organic Chemistry, Membrane Transport Proteins, Stereoisomerism, Antidepressive Agents, Norepinephrine transporter, chemistry, Microsomes, Liver, biology.protein, Catecholamine, Molecular Medicine, Serotonin, Reuptake inhibitor, Selective Serotonin Reuptake Inhibitors, medicine.drug
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المؤلفون: Stephen N. Mitchell, Robert G Greenslade
المصدر: Neuropharmacology. 47:1-8
مصطلحات موضوعية: Agonist, Microdialysis, medicine.medical_specialty, medicine.drug_class, Dopamine, Phencyclidine, Nucleus accumbens, Receptors, Metabotropic Glutamate, Nucleus Accumbens, Cellular and Molecular Neuroscience, Dopamine receptor D1, Internal medicine, medicine, Animals, Amino Acids, Pharmacology, Chemistry, Extracellular Fluid, Rats, Inbred Strains, Bridged Bicyclo Compounds, Heterocyclic, Rats, Kinetics, Endocrinology, Metabotropic receptor, Metabotropic glutamate receptor, Neuroscience, medicine.drug
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المؤلفون: Stephen N. Mitchell, Sarah Moss, Lucy H Goodhead, Andrew Sharott
المصدر: European Journal of Pharmacology. 460:117-125
مصطلحات موضوعية: Atropine, Bridged-Ring Compounds, Male, Agonist, Nicotine, medicine.medical_specialty, Carbachol, Pyridines, medicine.drug_class, Dopamine, Microdialysis, Muscarinic Antagonists, Cholinergic Agonists, Diamines, Muscarinic Agonists, Nucleus accumbens, Bicuculline, Hippocampus, Nucleus Accumbens, chemistry.chemical_compound, Internal medicine, Thiadiazoles, Muscarinic acetylcholine receptor, medicine, Oxotremorine, Methoctramine, Animals, Spiro Compounds, Pharmacology, Chemistry, Pilocarpine, Subiculum, Receptors, Muscarinic, Rats, Endocrinology, nervous system, Tropanes, medicine.drug
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المؤلفون: Stephen N. Mitchell, M.H. Joseph, Jeffrey A. Gray, J. Chauveau, P. Boulenguez, S.L. Peters
المصدر: Journal of Psychopharmacology. 12:258-267
مصطلحات موضوعية: Male, Agonist, Serotonin, medicine.medical_specialty, Indoles, Microinjections, RU-24,969, medicine.drug_class, Dopamine, Microdialysis, Glutamic Acid, Kainate receptor, Nucleus accumbens, Hippocampus, Receptors, N-Methyl-D-Aspartate, Nucleus Accumbens, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Neural Pathways, medicine, Animals, Pharmacology (medical), Pharmacology, Rats, Serotonin Receptor Agonists, 030227 psychiatry, Dizocilpine, Psychiatry and Mental health, Endocrinology, chemistry, Receptors, Serotonin, Receptor, Serotonin, 5-HT1B, Schizophrenia, CNQX, NMDA receptor, Excitatory Amino Acid Antagonists, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Gary Gilmour, Stephen N. Mitchell, Trevor W. Robbins, Francois Gastambide, Mark D. Tricklebank
المصدر: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 23(11)
مصطلحات موضوعية: Male, Reinforcement Schedule, Time Factors, Phencyclidine, Inhibitory postsynaptic potential, Cognition, medicine, Reaction Time, Animals, Pharmacology (medical), Ketamine, Effects of sleep deprivation on cognitive performance, Biological Psychiatry, Pharmacology, Cognitive flexibility, medicine.disease, Rats, Psychiatry and Mental health, Neurology, Schizophrenia, NMDA receptor, Conditioning, Operant, Neurology (clinical), Psychology, Neuroscience, Excitatory Amino Acid Antagonists, medicine.drug
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المصدر: Pharmacology Biochemistry and Behavior. 49:511-521
مصطلحات موضوعية: Male, Nicotine, medicine.medical_specialty, Sympathetic Nervous System, Clinical Biochemistry, Hippocampus, Water maze, Toxicology, Nucleus basalis, Biochemistry, Choline O-Acetyltransferase, Rats, Sprague-Dawley, Lesion, Norepinephrine, Behavioral Neuroscience, Cognition, Prosencephalon, Memory, Parasympathetic Nervous System, Internal medicine, medicine, Animals, Autonomic Pathways, Maze Learning, Biological Psychiatry, Brain Chemistry, Pharmacology, Rats, Memory, Short-Term, Endocrinology, Forebrain, Cholinergic, medicine.symptom, Psychology, Neuroscience, Acetylcholine, medicine.drug
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المؤلفون: G. A. Grigor'yan, Sharon Dawe, Jeffrey A. Gray, Helen Hodges, M.H. Joseph, Stephen N. Mitchell
المصدر: Drug Development Research. 31:3-17
مصطلحات موضوعية: medicine.medical_specialty, Tyrosine hydroxylase, Nucleus accumbens, Nicotine, Endocrinology, Latent inhibition, Neurochemical, Dopamine, Internal medicine, Drug Discovery, medicine, Cholinergic, Locus coeruleus, Psychology, Neuroscience, medicine.drug
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المؤلفون: Kavita, Prasad, Elizabeth, Tarasewicz, Pamela A Ohman, Strickland, Michael, O'Neill, Stephen N, Mitchell, Kalpana, Merchant, Samnang, Tep, Kathryn, Hilton, Akash, Datwani, Manuel, Buttini, Sarah, Mueller-Steiner, Eric K, Richfield
المصدر: The European journal of neuroscience. 33(4)
مصطلحات موضوعية: Mice, Knockout, Neurons, Substance-Related Disorders, Mice, Transgenic, Neurodegenerative Diseases, Hippocampus, Corpus Striatum, Article, Mice, Inbred C57BL, Mice, Catecholamines, Synapses, alpha-Synuclein, Animals, Humans, Transgenes, Chromatography, High Pressure Liquid
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المؤلفون: J.A. Gray, Stephen N. Mitchell, K.M. Smith, M.H. Joseph
المصدر: Neuroscience. 56:989-997
مصطلحات موضوعية: Male, Nicotine, medicine.medical_specialty, Tyrosine 3-Monooxygenase, Hypothalamus, Nerve Tissue Proteins, Hippocampus, Rats, Sprague-Dawley, Norepinephrine, Internal medicine, medicine, Animals, RNA, Messenger, Enzyme inducer, biology, Tyrosine hydroxylase, General Neuroscience, Biological Transport, Stimulation, Chemical, Rats, Ventral tegmental area, medicine.anatomical_structure, Endocrinology, Enzyme Induction, Potassium, Catecholamine, biology.protein, Locus coeruleus, Locus Coeruleus, Body region, medicine.drug