المؤلفون: Eric WFW Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, A Christopher Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo, Paula Carvelli, Mario Chan, Seng H Cheng, David S Collie, Steve Cunningham, Heather E Davidson, Gwyneth Davies, Jane C Davies, Lee A Davies, Maria H Dewar, Ann Doherty, Jackie Donovan, Natalie S Dwyer, Hala I Elgmati, Rosanna F Featherstone, Jemyr Gavino, Sabrina Gea-Sorli, Duncan M Geddes, James SR Gibson, Deborah R Gill, Andrew P Greening, Uta Griesenbach, David M Hansell, Katharine Harman, Tracy E Higgins, Samantha L Hodges, Stephen C Hyde, Laura Hyndman, J Alastair Innes, Joseph Jacob, Nancy Jones, Brian F Keogh, Maria P Limberis, Paul Lloyd-Evans, Alan W Maclean, Michelle C Manvell, Dominique McCormick, Michael McGovern, Gerry McLachlan, Cuixiang Meng, M Angeles Montero, Hazel Milligan, Laura J Moyce, Gordon D Murray, Andrew G Nicholson, Tina Osadolor, Javier Parra-Leiton, David J Porteous, Ian A Pringle, Emma K Punch, Kamila M Pytel, Alexandra L Quittner, Gina Rivellini, Clare J Saunders, Ronald K Scheule, Sarah Sheard, Nicholas J Simmonds, Keith Smith, Stephen N Smith, Najwa Soussi, Samia Soussi, Emma J Spearing, Barbara J Stevenson, Stephanie G Sumner-Jones, Minna Turkkila, Rosa P Ureta, Michael D Waller, Marguerite Y Wasowicz, James M Wilson, Paul Wolstenholme-Hogg, on behalf of the UK Cystic Fibrosis Gene Therapy Consortium

المصدر: Efficacy and Mechanism Evaluation, Vol 3, Iss 5 (2016)

مصطلحات موضوعية: cystic fibrosis, gene therapy, liposome, plasmid, clinical trial, randomised controlled trial, cftr, cystic fibrosis transmembrane conductance regulator, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2050-4365; https://doaj.org/toc/2050-4373

URL الوصول: https://doaj.org/article/09b29fe1b155492fba24a177fe4be24c

المؤلفون: Kenneth L Clark, Stephen A Hughes, Pallav Bulsara, Jill Coates, Kitty Moores, Joel Parry, Michael Carr, Ruth J Mayer, Paul Wilson, Chris Gruenloh, Daren Levin, Jill Darton, Wolf-Michael Weber, Katja Sobczak, Deborah R Gill, Stephen C Hyde, Lee A Davies, Ian A Pringle, Stephanie G Sumner-Jones, Vasant Jadhav, Sharon Jamison, Walter R Strapps, Victoria Pickering, Mark R Edbrooke

المصدر: Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)

مصطلحات موضوعية: cystic fibrosis, ENaC, GSK2225745, siRNA, therapeutic, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253116301251; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/b78fb7e93ba44314a82b90606a64ce1b

المؤلفون: Altar M. Munis, Benjamin Wright, Frederic Jackson, Helen Lockstone, Stephen C. Hyde, Catherine M. Green, Deborah R. Gill

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 62-70 (2022)

مصطلحات موضوعية: RNA-seq, SALI, SPB, surfactant, ATII, ATI, Genetics, QH426-470, Cytology, QH573-671

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121001789; https://doaj.org/toc/2329-0501; https://doaj.org/article/81b582810f854445b47efeadc72469e4

الاتاحة: https://doi.org/10.1016/j.omtm.2021.11.006
https://doaj.org/article/81b582810f854445b47efeadc72469e4

المؤلفون: Rosie J. Munday, Tiziana Coradin, Rachael Nimmo, Yatish Lad, Stephen C. Hyde, Kyriacos Mitrophanos, Deborah R. Gill

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 239-252 (2022)

مصطلحات موضوعية: lentiviral vector, pseudotype, human airway, Sendai virus, avian influenza virus, sialic acid, Genetics, QH426-470, Cytology, QH573-671

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122000948; https://doaj.org/toc/2329-0501; https://doaj.org/article/241605041a2345d097db4e7ae694bd95

الاتاحة: https://doi.org/10.1016/j.omtm.2022.07.002
https://doaj.org/article/241605041a2345d097db4e7ae694bd95

المؤلفون: Yue Du, Shengnan Zhang, Zhaoyong Zhang, Kamran M. Miah, Peilan Wei, Lu Zhang, Yuhui Zhu, Zhengtu Li, Feng Ye, Deborah R. Gill, Stephen C. Hyde, Yanqun Wang, Jincun Zhao

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: monoclonal neutralizing antibody, SIV.F/HN vectored immunoprophylaxis, COVID-19, old and immunodeficient mice, passive immunoprophylaxis, Immunologic diseases. Allergy, RC581-607

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.819058/full; https://doaj.org/toc/1664-3224; https://doaj.org/article/882b0663b0c74c2d88e868f70d05fc7a

الاتاحة: https://doi.org/10.3389/fimmu.2022.819058
https://doaj.org/article/882b0663b0c74c2d88e868f70d05fc7a

المؤلفون: Altar M. Munis, Stephen C. Hyde, Deborah R. Gill

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 237-246 (2021)

مصطلحات موضوعية: Surfactant B deficiency, SPB, lentiviral vectors, rSIV.F/HN, lentivirus, gene therapy, Genetics, QH426-470, Cytology, QH573-671

Relation: http://www.sciencedirect.com/science/article/pii/S2329050120302400; https://doaj.org/toc/2329-0501; https://doaj.org/article/ce065d88a2414cff8e78d523fca519d4

الاتاحة: https://doi.org/10.1016/j.omtm.2020.11.013
https://doaj.org/article/ce065d88a2414cff8e78d523fca519d4

المؤلفون: Agata Antepowicz, Omar Habib, Freja Kirsebom, Cecilia Johansson, Deborah R. Gill, Stephen C. Hyde

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-021-95150-z; https://doaj.org/toc/2045-2322; https://doaj.org/article/02a847cbdd3747d0b7746de8f6676a1b

الاتاحة: https://doi.org/10.1038/s41598-021-95150-z
https://doaj.org/article/02a847cbdd3747d0b7746de8f6676a1b

المؤلفون: Altar M. Munis, Monique Andersson, Alexander Mobbs, Stephen C. Hyde, Deborah R. Gill

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-021-01022-x; https://doaj.org/toc/2045-2322; https://doaj.org/article/0f5350e19d5d4b4dbc98ab52f66eb2ac

الاتاحة: https://doi.org/10.1038/s41598-021-01022-x
https://doaj.org/article/0f5350e19d5d4b4dbc98ab52f66eb2ac

المؤلفون: Gerry McLachlan, Eric W.F.W. Alton, A. Christopher Boyd, Nora K. Clarke, Jane C. Davies, Deborah R. Gill, Uta Griesenbach, Jack W. Hickmott, Stephen C. Hyde, Kamran M. Miah, Claudia Juarez Molina

المصدر: McLachlan, G, Alton, E W, Boyd, A C, Clark, N, Davies, J C, Gill, D R, Griesenbach, U, Hickmott, J, Hyde, S C, Miah, K & Juarez Molina, C 2022, ' Progress in Respiratory Gene Therapy ', Human Gene Therapy, vol. 33, no. 17-18, pp. 893-912 . https://doi.org/10.1089/hum.2022.172

مصطلحات موضوعية: Peptide Nucleic Acids, lung disease, gene editing, Genetic Vectors, Gene Transfer Techniques, AAV, gene therapy vectors, DNA, Genetic Therapy, Oligonucleotides, Antisense, respiratory, lentivirus, Genetics, Molecular Medicine, RNA, Messenger, RNA, Small Interfering, Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0eeccb4804c0c9d17243429c478d77
https://doi.org/10.1089/hum.2022.172

المؤلفون: Helena Meyer-Berg, Lucia Zhou Yang, María Pilar de Lucas, Alberto Zambrano, Stephen C. Hyde, Deborah R. Gill

المصدر: Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-6 (2020)

مصطلحات موضوعية: human embryonic stem cells, stem cell-based tissue model, gene therapy, rAAV, AAV capsids, AAV serotypes, Medicine (General), R5-920, Biochemistry, QD415-436

Relation: http://link.springer.com/article/10.1186/s13287-020-01950-x; https://doaj.org/toc/1757-6512; https://doaj.org/article/cfd60483467343929fab9a7c02913e3f

الاتاحة: https://doi.org/10.1186/s13287-020-01950-x
https://doaj.org/article/cfd60483467343929fab9a7c02913e3f

المؤلفون: Helena Lund-Palau, Claudia Ivette Juarez-Molina, Cuixiang Meng, Anushka Bhargava, Aikaterini Pilou, Kiran Aziz, Nora Clarke, Naoko Atsumi, Ali Ashek, Michael R. Wilson, Masao Takata, Simon Padley, Deborah R. Gill, Stephen C. Hyde, Cliff Morgan, Eric W.F.W. Alton, Uta Griesenbach

المصدر: Molecular Therapy - Methods & Clinical Development. 25:382-391

مصطلحات موضوعية: autoimmune pulmonary alveolar proteinosis, PAP, granulocyte-macrophage colony-stimulating factor, lentiviral vector, Genetics, rSIV.F/HN, Molecular Medicine, GM-CSF, surfactant protein, alveolar macrophage, lung gene therapy, gene therapy, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309e84486c01c19b098f536c41ae5049
https://doi.org/10.1016/j.omtm.2022.04.002

المؤلفون: Yue Du, Kamran M Miah, Omar Habib, Helena Meyer-Berg, Catriona C Conway, Mariana A Viegas, Rebecca Dean, Dwiantari Satyapertiwi, Jincun Zhao, Yanqun Wang, Nigel J Temperton, Toby P E Gamlen, Deborah R Gill, Stephen C Hyde

المصدر: Thorax. 77:1229-1236

مصطلحات موضوعية: QR355, Pulmonary and Respiratory Medicine, COVID-19 Vaccines, SARS-CoV-2, COVID-19, biochemical phenomena, metabolism, and nutrition, Antibodies, Viral, Antibodies, Neutralizing, Mice, Humans, Animals, Pandemics, Lung, Aged

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b3e9155f92e16f44421988c17acda5
https://doi.org/10.1136/thoraxjnl-2021-217650

المؤلفون: Stephen C. Hyde, Julian C. Knight, Fadi Issa, Amy Cross, Damien J. Downes, S N Sansom, Nigel A. Roberts, Peng Hua, Ron Schwessinger, Olga Mielczarek, C. De Andrea, Davies Joj., Altar M. Munis, Antony J. Cutler, Jim R. Hughes, Deborah R. Gill, Ignacio Melero, Jill M. Brown, John A. Todd

المصدر: Nature Genetics. 53:1606-1615

مصطلحات موضوعية: Male, Leucine zipper, Epithelial-Mesenchymal Transition, Locus (genetics), Genome-wide association study, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, Allele, Enhancer, Lung, Gene, Transcription factor, 030304 developmental biology, 0303 health sciences, SARS-CoV-2, Effector, COVID-19, Epithelial Cells, 3. Good health, Case-Control Studies, 030220 oncology & carcinogenesis, Cancer research, Female, Chromosomes, Human, Pair 3, Genome-Wide Association Study, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa7deb797423fb5831e970856ffba02
https://doi.org/10.1038/s41588-021-00955-3

المؤلفون: null Patricia P. Ogger, null Minerva Garcia Martín, null Christina Michalaki, null Jie Zhou, null Jonathan C. Brown, null Yue Du, null Kamran M. Miah, null Omar Habib, null Stephen C. Hyde, null Deborah R. Gill, null Wendy S. Barclay, null Cecilia Johansson

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ab2b52f860cd194835530db57e0768f4
https://doi.org/10.1002/eji.202249913/v3/response1

المؤلفون: Stephen C. Hyde, Deborah R. Gill, Freja C M Kirsebom, Agata Antepowicz, Cecilia Johansson, Omar Habib

المساهمون: Wellcome Trust

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

مصطلحات موضوعية: Palivizumab, Genetic enhancement, viruses, Science, Genetic Vectors, Gene Expression, Respiratory Syncytial Virus Infections, Gene delivery, Antibodies, Monoclonal, Humanized, medicine.disease_cause, Injections, Intramuscular, Article, Virus, Viral vector, Mice, Gene therapy, Transduction, Genetic, Animals, Medicine, Nucleic-acid therapeutics, Respiratory system, Multidisciplinary, business.industry, Lentivirus, Gene Transfer Techniques, Genetic Therapy, Dependovirus, Simian immunodeficiency virus, Virology, Respiratory Syncytial Viruses, Disease Models, Animal, Treatment Outcome, Murine model, Female, Genetic Engineering, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9601bac6ee73b9a37398e3e424d50859
https://doaj.org/article/02a847cbdd3747d0b7746de8f6676a1b

المؤلفون: Yue, Du, Shengnan, Zhang, Zhaoyong, Zhang, Kamran M, Miah, Peilan, Wei, Lu, Zhang, Yuhui, Zhu, Zhengtu, Li, Feng, Ye, Deborah R, Gill, Stephen C, Hyde, Yanqun, Wang, Jincun, Zhao

مصطلحات موضوعية: COVID-19 Vaccines, SARS-CoV-2, Immunology, Antibodies, Monoclonal, COVID-19, Mice, SCID, Antibodies, Viral, Antibodies, Neutralizing, Mice, Immunoglobulin G, Spike Glycoprotein, Coronavirus, Animals, Humans, Immunology and Allergy, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0553130f4b4b1e6e53b9ebd0a7d546d
https://ora.ox.ac.uk/objects/uuid:0a008c18-cfd7-4f5d-8819-5251817e3c88

المؤلفون: Yue Du, Shengnan Zhang, Zhaoyong Zhang, Kamran M. Miah, Peilan Wei, Lu Zhang, Yuhui Zhu, Zhengtu Li, Feng Ye, Deborah R. Gill, Stephen C. Hyde, Yanqun Wang, Jincun Zhao

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, monoclonal neutralizing antibody, SIV.F/HN vectored immunoprophylaxis, COVID-19, old and immunodeficient mice, passive immunoprophylaxis

Relation: https://figshare.com/articles/dataset/DataSheet_1_Intranasal_Lentiviral_Vector-Mediated_Antibody_Delivery_Confers_Reduction_of_SARS-CoV-2_Infection_in_Elderly_and_Immunocompromised_Mice_pdf/19634148

الاتاحة: https://doi.org/10.3389/fimmu.2022.819058.s001
https://figshare.com/articles/dataset/DataSheet_1_Intranasal_Lentiviral_Vector-Mediated_Antibody_Delivery_Confers_Reduction_of_SARS-CoV-2_Infection_in_Elderly_and_Immunocompromised_Mice_pdf/19634148

المؤلفون: Stephen C. Hyde, Kamran M Miah, Deborah R. Gill

المصدر: Expert Review of Respiratory Medicine. 13:709-725

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Cystic Fibrosis, Genetic enhancement, Genetic Vectors, Cystic Fibrosis Transmembrane Conductance Regulator, Disease, Gene delivery, Bioinformatics, Cystic fibrosis, Viral vector, 03 medical and health sciences, 0302 clinical medicine, Genome editing, Animals, Humans, Immunology and Allergy, Medicine, 030212 general & internal medicine, Vector (molecular biology), Gene, Gene Editing, business.industry, Public Health, Environmental and Occupational Health, Genetic Therapy, medicine.disease, 030228 respiratory system, Mutation, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0a9ec9b3e8cab7341a91d378316578
https://doi.org/10.1080/17476348.2019.1634547

المؤلفون: Lee A. Davies, Graciela A. Nunez-Alonso, Henry L. Hebel, Ron K. Scheule, Seng H. Cheng, Stephen C. Hyde, Deborah R. Gill

المصدر: BioTechniques, Vol 49, Iss 3, Pp 666-668 (2010)

مصطلحات موضوعية: Gene therapy, nonviral formulations, lipoplexes, polyplexes, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

URL الوصول: https://doaj.org/article/3e046d23ba124e4cbd0b7377bfd128a7

المؤلفون: Stephen C. Hyde, Gill, Jane C. Davies, Gerry McLachlan, Amanda Boyd, Ewfw Alton, T E Harman, Uta Griesenbach

المصدر: Therapeutic advances in cystic fibrosis: today and tomorrow.

مصطلحات موضوعية: education.field_of_study, biology, business.industry, Genetic enhancement, Population, Context (language use), Simian immunodeficiency virus, biology.organism_classification, medicine.disease_cause, Viral vector, Clinical trial, Transduction (genetics), Lentivirus, Cancer research, medicine, education, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1b4ad77782272d3691298082fadbc17c
https://doi.org/10.1136/thorax-2020-btsabstracts.73