المؤلفون: Emily D Crawford, Irene Acosta, Vida Ahyong, Erika C Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S Azimi, Caleigh M Azumaya, Stefanie Bachl, Iris Bachmutsky, Aparna Bhaduri, Jeremy Bancroft Brown, Joshua Batson, Astrid Behnert, Ryan M Boileau, Saumya R Bollam, Alain R Bonny, David Booth, Michael Jerico B Borja, David Brown, Bryan Buie, Cassandra E Burnett, Lauren E Byrnes, Katelyn A Cabral, Joana P Cabrera, Saharai Caldera, Gabriela Canales, Gloria R Castañeda, Agnes Protacio Chan, Christopher R Chang, Arthur Charles-Orszag, Carly Cheung, Unseng Chio, Eric D Chow, Y Rose Citron, Allison Cohen, Lillian B Cohn, Charles Chiu, Mitchel A Cole, Daniel N Conrad, Angela Constantino, Andrew Cote, Tre'Jon Crayton-Hall, Spyros Darmanis, Angela M Detweiler, Rebekah L Dial, Shen Dong, Elias M Duarte, David Dynerman, Rebecca Egger, Alison Fanton, Stacey M Frumm, Becky Xu Hua Fu, Valentina E Garcia, Julie Garcia, Christina Gladkova, Miriam Goldman, Rafael Gomez-Sjoberg, M Grace Gordon, James C R Grove, Shweta Gupta, Alexis Haddjeri-Hopkins, Pierce Hadley, John Haliburton, Samantha L Hao, George Hartoularos, Nadia Herrera, Melissa Hilberg, Kit Ying E Ho, Nicholas Hoppe, Shayan Hosseinzadeh, Conor J Howard, Jeffrey A Hussmann, Elizabeth Hwang, Danielle Ingebrigtsen, Julia R Jackson, Ziad M Jowhar, Danielle Kain, James Y S Kim, Amy Kistler, Oriana Kreutzfeld, Jessie Kulsuptrakul, Andrew F Kung, Charles Langelier, Matthew T Laurie, Lena Lee, Kun Leng, Kristoffer E Leon, Manuel D Leonetti, Sophia R Levan, Sam Li, Aileen W Li, Jamin Liu, Heidi S Lubin, Amy Lyden, Jennifer Mann, Sabrina Mann, Gorica Margulis, Diana M Marquez, Bryan P Marsh, Calla Martyn, Elizabeth E McCarthy, Aaron McGeever, Alexander F Merriman, Lauren K Meyer, Steve Miller, Megan K Moore, Cody T Mowery, Tanzila Mukhtar, Lusajo L Mwakibete, Noelle Narez, Norma F Neff, Lindsay A Osso, Diter Oviedo, Suping Peng, Maira Phelps, Kiet Phong, Peter Picard, Lindsey M Pieper, Neha Pincha, Angela Oliveira Pisco, Angela Pogson, Sergei Pourmal, Robert R Puccinelli, Andreas S Puschnik, Elze Rackaityte, Preethi Raghavan, Madhura Raghavan, James Reese, Joseph M Replogle, Hanna Retallack, Helen Reyes, Donald Rose, Marci F Rosenberg, Estella Sanchez-Guerrero, Sydney M Sattler, Laura Savy, Stephanie K See, Kristin K Sellers, Paula Hayakawa Serpa, Maureen Sheehy, Jonathan Sheu, Sukrit Silas, Jessica A Streithorst, Jack Strickland, Doug Stryke, Sara Sunshine, Peter Suslow, Renaldo Sutanto, Serena Tamura, Michelle Tan, Jiongyi Tan, Alice Tang, Cristina M Tato, Jack C Taylor, Iliana Tenvooren, Erin M Thompson, Edward C Thornborrow, Eric Tse, Tony Tung, Marc L Turner, Victoria S Turner, Rigney E Turnham, Mary J Turocy, Trisha V Vaidyanathan, Ilia D Vainchtein, Manu Vanaerschot, Sara E Vazquez, Anica M Wandler, Anne Wapniarski, James T Webber, Zara Y Weinberg, Alexandra Westbrook, Allison W Wong, Emily Wong, Gajus Worthington, Fang Xie, Albert Xu, Terrina Yamamoto, Ying Yang, Fauna Yarza, Yefim Zaltsman, Tina Zheng, Joseph L DeRisi

المصدر: PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140

المؤلفون: David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James S Fraser

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: deep mutational scanning, ubiquitin, proteostasis, chemical biology, proteasome, biophysics, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/15802; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/f3e8373dbc7b4012a1c82425c9fb49fb

المؤلفون: Kevin G. Mark, SriDurgaDevi Kolla, Danielle M. Garshott, Brenda Martínez-González, Christina Xu, David Akopian, Diane L. Haakonsen, Stephanie K. See, Michael Rapé

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e9d36bd75f0dd6ec54e0cf821dbd9d7a
https://doi.org/10.1101/2022.11.06.515368

المؤلفون: Gregory J. Krause, Antonio Diaz, Maryam Jafari, Rabia R. Khawaja, Esperanza Agullo‐Pascual, Olaya Santiago‐Fernández, Alicia L. Richards, Kuei‐Ho Chen, Phillip Dmitriev, Yan Sun, Stephanie K. See, Kotb Abdelmohsen, Krystyna Mazan‐Mamczarz, Nevan J. Krogan, Myriam Gorospe, Danielle L. Swaney, Simone Sidoli, Jose Javier Bravo‐Cordero, Martin Kampmann, Ana Maria Cuervo

المصدر: Aging cell. 21(10)

مصطلحات موضوعية: Aging, Mice, Protein Transport, Proteome, Microautophagy, Autophagy, Animals, Cell Biology, Endosomes, Lysosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f848aa4e2d822ac71c21de946e971a37
https://pubmed.ncbi.nlm.nih.gov/36116133

المؤلفون: Keely Oltion, Jordan D. Carelli, Tangpo Yang, Stephanie K. See, Hao-Yuan Wang, Martin Kampmann, Jack Taunton

المصدر: Cell. 186:346-362.e17

مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3a4f0e2b851317031dfbbb81bdbe2de6
https://doi.org/10.1016/j.cell.2022.12.025

المؤلفون: Amanda L. Woerman, Daniel R. Southworth, Merissa Chen, Sophie Bax, Elise N Munoz, Ruilin Tian, Martin Kampmann, Isabel E. Johnson, Stephanie K. See, Eric Tse, Janine Sengstack, Carlos Nowotny, Manuel D. Leonetti, Jason E. Gestwicki

مصطلحات موضوعية: CRISPR interference, Chemistry, animal diseases, Fibril, nervous system diseases, law.invention, Cell biology, Cytosol, PIKFYVE, medicine.anatomical_structure, nervous system, law, Lysosome, mental disorders, Recombinant DNA, medicine, Secretion, α synuclein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::088c2f93a71b4693e2cacba634749827
https://doi.org/10.1101/2021.01.21.427704

المؤلفون: Becky Xu Hua Fu, Erin M. Thompson, Agnes Protacio Chan, Zara Y. Weinberg, Alain R Bonny, Samantha Hao, Nicholas Hoppe, Aparna Bhaduri, Angela Constantino, Fauna Yarza, Suping Peng, Lillian B. Cohn, Gajus Worthington, Paula Hayakawa Serpa, Diana M. Marquez, Rafael Gomez-Sjoberg, Saharai Caldera, Norma Neff, Neha Pincha, Peter Picard, Andrew Cote, Diter Oviedo, Shayan Hosseinzadeh, Robert Puccinelli, Danielle Ingebrigtsen, Serena Tamura, Sergei Pourmal, Jeffrey A. Hussmann, Anica M. Wandler, M. Grace Gordon, Irene Acosta, Shweta Gupta, Jeremy Bancroft Brown, Joseph L. DeRisi, Shannon Axelrod, Andreas S. Puschnik, Lindsey M. Pieper, Joseph M. Replogle, Valentina E. Garcia, James Reese, Patrick Ayscue, Arthur Charles-Orszag, Iliana Tenvooren, Eric Tse, Alison Fanton, Elze Rackaityte, Charles Y. Chiu, Aileen W. Li, Edward Thornborrow, Amy Lyden, Katelyn A. Cabral, Sukrit Silas, Kun Leng, Erika Anderson, Lusajo L. Mwakibete, Shaun Arevalo, Gabriela Canales, Calla Martyn, Gorica Margulis, Andrew F. Kung, Sophia R. Levan, Tanzila Mukhtar, Carly K. Cheung, Jonathan Sheu, Sam Li, Charles Langelier, Gloria Castaneda, Tina Zheng, Maureen Sheehy, Rebecca Egger, Amy Kistler, Alexander F. Merriman, Sara Sunshine, Cody T. Mowery, Madhura Raghavan, Allison Cohen, Terrina Yamamoto, Mitchel A. Cole, Saumya R. Bollam, Megan Moore, Preethi Raghavan, Jessie Kulsuptrakul, Stacey M. Frumm, Manu Vanaerschot, Fang Xie, Daniel Asarnow, Miriam Goldman, Pierce Hadley, Sara E. Vazquez, Michelle Tan, Kristin K. Sellers, Lindsay A. Osso, Lauren K. Meyer, Daniel N. Conrad, Sabrina A Mann, Vida Ahyong, Kristoffer E. Leon, Un Seng Chio, Camillia S. Azimi, Bryan Marsh, Anne E. Wapniarski, Stefanie Bachl, Kit Ying E. Ho, Rigney E. Turnham, Aaron McGeever, Cassandra E. Burnett, Rebekah Dial, Caleigh M. Azumaya, Helen Reyes, Victoria S. Turner, Jiongyi Tan, Emily D. Crawford, Allison W. Wong, Spyros Darmanis, Shen Dong, Lena Lee, Y. Rose Citron, Christopher R. Chang, Astrid Behnert, Ziad M. Jowhar, Nadia Herrera, Doug Stryke, Lauren Byrnes, Albert Xu, James C. R. Grove, Cristina M. Tato, George C. Hartoularos, Tony Tung, Iris Bachmutsky, Ryan M. Boileau, Peter Suslow, Jessica Streithorst, Alexis Haddjeri-Hopkins, John R. Haliburton, Conor J Howard, Angela Oliveira Pisco, Eric D. Chow, Elizabeth E. McCarthy, Joshua Batson, Oriana Kreutzfeld, Elizabeth Hwang, Hanna Retallack, Danielle Kain, Alice Tang, Jack C. Taylor, Emily C. Wong, Donald Rose, Julia R. Jackson, Alexandra Westbrook, Matthew T. Laurie, Jennifer Mann, Renaldo Sutanto, Mary J. Turocy, Trisha V. Vaidyanathan, Melissa Hilberg, Stephanie K. See, David S. Booth, Christina Gladkova, Jack Strickland, Julie M. Garcia, Marc L. Turner, David Dynerman, Manuel D. Leonetti, Laura Savy, Noelle Narez, Jamin Liu, Ilia D. Vainchtein, Ying Yang, Kiet T. Phong, Tre’Jon Crayton-Hall, David Brown, Marci F. Rosenberg, Bryan Buie, Maira Phelps, Sydney M. Sattler, Elias Duarte, Yefim Zaltsman, Angela M. Detweiler, Estella Sanchez-Guerrero, Joana P. Cabrera, Michael Jerico B. Borja, James Y. S. Kim, Heidi S. Lubin, Angela Pogson, Steve Miller, James T. Webber

المصدر: PLoS Pathogens, Vol 16, Iss 10, p e1008966 (2020)
PLoS Pathogens

مصطلحات موضوعية: RNA viruses, Viral Diseases, Critical Care and Emergency Medicine, Epidemiology, Coronaviruses, Social Sciences, California, Workflow, Medical Conditions, COVID-19 Testing, Medicine and Health Sciences, Public and Occupational Health, Biology (General), Pathology and laboratory medicine, media_common, Virus Testing, 0303 health sciences, 030302 biochemistry & molecular biology, Art, Medical microbiology, Clinical Laboratory Services, Clinical Laboratory Sciences, Clinical Laboratories, Infectious Diseases, Viruses, SARS CoV 2, Pathogens, Coronavirus Infections, 2019-20 coronavirus outbreak, Opinion, Coronavirus disease 2019 (COVID-19), SARS coronavirus, QH301-705.5, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), media_common.quotation_subject, Immunology, Pneumonia, Viral, Microbiology, 03 medical and health sciences, Betacoronavirus, Diagnostic Medicine, Virology, Genetics, Humans, Molecular Biology, Pandemics, Regulations, 030304 developmental biology, Biology and life sciences, Clinical Laboratory Techniques, SARS-CoV-2, Organisms, Viral pathogens, COVID-19, Covid 19, RC581-607, Microbial pathogens, Parasitology, Law and Legal Sciences, Immunologic diseases. Allergy, Humanities

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f769d674844a50804f8ecde46fb4c3
https://doaj.org/article/3bbb68a359bd42bc9db996dc6d89e140

المؤلفون: Manuel D. Leonetti, Jason E. Gestwicki, Eric Tse, Martin Kampmann, Maxine Nelson, Preethi Raghavan, Diane Nathaniel, Stephanie K. See, Jason Y. Hong, Daniel R. Southworth, Marco Y. Hein, John J. Chen, Ruilin Tian, Sue-Ann Mok, Lea T. Grinberg

المصدر: The Journal of biological chemistry, vol 294, iss 50

مصطلحات موضوعية: 0301 basic medicine, Aging, endosomal sorting complexes required for transport, fluorescence resonance energy transfer, Neurodegenerative, Protein aggregation, Alzheimer's Disease, Medical and Health Sciences, Biochemistry, 0302 clinical medicine, 2.1 Biological and endogenous factors, Aetiology, Cells, Cultured, 0303 health sciences, Gene knockdown, Cultured, Chemistry, Biological Sciences, Cell biology, Frontotemporal Dementia (FTD), medicine.anatomical_structure, Neurological, lysosome, functional genomics, Functional genomics, Intracellular, Biochemistry & Molecular Biology, Endosome, Cells, 1.1 Normal biological development and functioning, Membrane damage, tau Proteins, ESCRT, protein aggregation, 03 medical and health sciences, Protein Aggregates, CRISPR/Cas, Rare Diseases, Underpinning research, Lysosome, mental disorders, Tau protein, Acquired Cognitive Impairment, medicine, Compartment (development), Humans, Editors' Picks, endosome, Molecular Biology, 030304 developmental biology, CRISPR interference, 030102 biochemistry & molecular biology, Endosomal Sorting Complexes Required for Transport, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Cell Biology, Brain Disorders, Emerging Infectious Diseases, 030104 developmental biology, HEK293 Cells, Cytoplasm, Chemical Sciences, Dementia, Generic health relevance, Lysosomes, 030217 neurology & neurosurgery, Function (biology)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a0a5cb6e736cc2999c709de9e0a537

المؤلفون: Ruta Zalyte, Maxence V. Nachury, Andrew P. Carter, Rand M. Miller, Fan Ye, Tommaso Cupido, Jonathan B. Steinman, Andrew H. Chung, Tarun M. Kapoor, Sascha Hoogendoorn, Stephanie K. See, Tomoyo Sakata-Kato, James K. Chen

المصدر: See, SK; Hoogendoorn, S; Chung, AH; Ye, F; Steinman, JB; Sakata-Kato, T; et al.(2016). Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity. ACS CHEMICAL BIOLOGY, 11(1), 53-60. doi: 10.1021/acschembio.5b00895. UCSF: Retrieved from: http://www.escholarship.org/uc/item/3tn1x71x
ACS Chemical Biology

مصطلحات موضوعية: Cytoplasmic Dyneins, 0301 basic medicine, Dynein, macromolecular substances, Biology, Biochemistry, Substrate Specificity, Mice, Structure-Activity Relationship, 03 medical and health sciences, Microtubule, Animals, Protein Isoforms, Structure–activity relationship, Hedgehog Proteins, Letters, Quinazolinones, Molecular Structure, Cilium, General Medicine, AAA proteins, Cell biology, 030104 developmental biology, NIH 3T3 Cells, Dynactin, Axoplasmic transport, Molecular Medicine, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e614c706382fcdbda3f462817e70ee6c
https://doi.org/10.1021/acschembio.5b00895

المؤلفون: Jennifer N. Rauch, Martin Kampmann, Kenneth S. Kosik, Alexander W. Sorum, John J. Chen, Gregory M. Miller, Tal Sharf, Linda C. Hsieh-Wilson, Stephanie K. See

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific reports, vol 8, iss 1
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Aging, Cell, lcsh:Medicine, Neurodegenerative, Alzheimer's Disease, Mice, Dynamin II, 0302 clinical medicine, Protein structure, Sulfation, Tumor Cells, Cultured, 2.1 Biological and endogenous factors, Aetiology, Internalization, lcsh:Science, media_common, 0303 health sciences, Cultured, Multidisciplinary, biology, Chemistry, Brain, Glioma, Genomics, Tumor Cells, 3. Good health, Cell biology, medicine.anatomical_structure, Biochemistry, Neurological, Sulfotransferases, Alzheimer's disease, Intracellular, Biotechnology, Protein Structure, media_common.quotation_subject, Tau protein, tau Proteins, N-Acetylglucosaminyltransferases, Article, Quaternary, 03 medical and health sciences, Slice preparation, mental disorders, Acquired Cognitive Impairment, Genetics, medicine, Animals, Humans, Protein Structure, Quaternary, 030304 developmental biology, lcsh:R, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), medicine.disease, Brain Disorders, 030104 developmental biology, Cell culture, biology.protein, Dementia, lcsh:Q, CRISPR-Cas Systems, Sulfur, Heparan Sulfate Proteoglycans, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/msword

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05def162063c219ae6323890d7904c25

المؤلفون: Clinton L. Cario, Seth D. Axen, Weiyue Ji, Kurt S. Thorn, Adolfo Cuesta, Daniel N. Bolon, Kaitlin R. Hulce, Kyle A. Barlow, Marco Mravic, Jennifer X. Li, Lillian R. Kenner, Garrett Gaskins, Eugenia C Salcedo, Elena L. Caceres, David Mavor, Stefan Niekamp, Allison W. Wong, Weilin Chen, Bruk Mensa, Samuel Thompson, Benjamin A Barad, Erin M. Poss, Ryan K Muir, Rachel E. Gate, Laura Deming, Zairan Liu, Shane Ó Conchúir, Joseph L. DeRisi, Meena Subramaniam, James S. Fraser, Evan M. Green, Eugene Palovcak, Tanja Kortemme, Tyler D Ross, Alain R Bonny, Steven M. Moss, Stephanie K. See, Chimno I Nnadi, Benjamin P. Roscoe, Leanna S. Morinishi, Eric D. Chow

مصطلحات موضوعية: Ubiquitin, biology, Fitness landscape, Evolutionary biology, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::93a8a47dec29f83dc18d99f9ad48e8e5
https://doi.org/10.7554/elife.15802.023

المؤلفون: Marco Mravic, Chimno I Nnadi, Weiyue Ji, Benjamin P. Roscoe, Benjamin A Barad, Clinton L. Cario, Meena Subramaniam, Bruk Mensa, Ryan K Muir, Weilin Chen, Jennifer X. Li, Leanna S. Morinishi, Adolfo Cuesta, Daniel N. Bolon, Garrett Gaskins, Rachel E. Gate, Lillian R. Kenner, Kyle A. Barlow, Stefan Niekamp, Allison W. Wong, Tanja Kortemme, Eric D. Chow, Alain R Bonny, Joseph L. DeRisi, Zairan Liu, Shane Ó Conchúir, Kurt S. Thorn, Samuel Thompson, Seth D. Axen, Eugenia C Salcedo, Stephanie K. See, Kaitlin R. Hulce, Erin M. Poss, Elena L. Caceres, James S. Fraser, Eugene Palovcak, Laura Deming, David Mavor, Tyler D Ross, Evan M. Green, Steven M. Moss

المصدر: eLife
eLife, Vol 5 (2016)

مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Universities, QH301-705.5, Fitness landscape, Science, DNA Mutational Analysis, S. cerevisiae, chemical biology, Saccharomyces cerevisiae, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Deep sequencing, 03 medical and health sciences, Ubiquitin, deep mutational scanning, Stress, Physiological, biophysics, medicine, Humans, Biology (General), Students, Biology, Genetics, Mutation, proteostasis, General Immunology and Microbiology, biology, General Neuroscience, General Medicine, Ubiquitin ligase, 030104 developmental biology, Proteostasis, proteasome, Proteasome, Genomics and Evolutionary Biology, biology.protein, Medicine, Mutant Proteins, Computational and Systems Biology, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3aa255e8efa144b140b0f3d04b5bbc
http://europepmc.org/articles/PMC4862753