المؤلفون: Saretz, Stefan, Basset, Gabriele, Useini, Liridona, Laube, Markus, Pietzsch, Jens, Draˇca, Dijana, Maksimovi´c-Ivani´c, Danijela, Trambauer, Johannes, Steiner, Harald, Hey-Hawkins, Evamarie

مصطلحات موضوعية: Alzheimer, carborane, flurbiprofen, γ-secretase modulator (GSM), small molecule, amyloid-β (Aβ) peptide, phenyl mimetic, info:eu-repo/classification/ddc/540, ddc:540

Relation: 2843

الاتاحة: https://ul.qucosa.de/id/qucosa%3A85294
https://ul.qucosa.de/api/qucosa%3A85294/attachment/ATT-0/

المؤلفون: Aßfalg, Marlene, Güner, Gökhan, Müller, Stephan A., Breimann, Stephan, Langosch, Dieter, Muhle-Goll, Claudia, Frishman, Dmitrij, Steiner, Harald, Lichtenthaler, Stefan F.

المصدر: The FASEB Journal, 38 (2), Art.-Nr.: e23442 ; ISSN: 0892-6638, 1530-6860

مصطلحات موضوعية: FXYD3, FXYD6, intramembrane proteolysis, LYRIC, PMEPA1, protease substrate specificity, TNR12, Tweak receptor, ddc:570, Life sciences, biology, info:eu-repo/classification/ddc/570

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/wos/001148757200001; info:eu-repo/semantics/altIdentifier/issn/0892-6638; info:eu-repo/semantics/altIdentifier/issn/1530-6860; https://publikationen.bibliothek.kit.edu/1000168147; https://publikationen.bibliothek.kit.edu/1000168147/152194929; https://doi.org/10.5445/IR/1000168147

الاتاحة: https://publikationen.bibliothek.kit.edu/1000168147
https://publikationen.bibliothek.kit.edu/1000168147/152194929
https://doi.org/10.5445/IR/1000168147

المؤلفون: Chen, Shu-Yu, Feilen, Lukas Peter, Chávez-Gutiérrez, Lucía, Steiner, Harald, Zacharias, Martin

المصدر: Communications biology 6(1), 670 (2023). doi:10.1038/s42003-023-05039-y

مصطلحات موضوعية: info:eu-repo/classification/ddc/570, Amyloid Precursor Protein Secretases: genetics, Amyloid Precursor Protein Secretases: metabolism, Catalytic Domain, Protein Conformation, beta-Strand, Amyloid beta-Protein Precursor: genetics, Amyloid beta-Protein Precursor: metabolism, Water Supply, Amyloid Precursor Protein Secretases, Amyloid beta-Protein Precursor

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:37355752; info:eu-repo/semantics/altIdentifier/issn/2399-3642; https://pub.dzne.de/record/258782; https://pub.dzne.de/search?p=id:%22DZNE-2023-00676%22

الاتاحة: https://pub.dzne.de/record/258782
https://pub.dzne.de/search?p=id:%22DZNE-2023-00676%22

المؤلفون: Schmidt, Fabian C, Fitz, Katja, Feilen, Lukas P, Okochi, Masayasu, Steiner, Harald, Langosch, Dieter

المصدر: The journal of biological chemistry 299(5), 104626 (2023). doi:10.1016/j.jbc.2023.104626

مصطلحات موضوعية: info:eu-repo/classification/ddc/540, Humans, Alzheimer Disease: metabolism, Amyloid beta-Peptides: genetics, Amyloid beta-Peptides: metabolism, Amyloid beta-Protein Precursor: metabolism, Amyloid Precursor Protein Secretases: genetics, Amyloid Precursor Protein Secretases: metabolism, Presenilin-1: chemistry, Presenilin-1: genetics, Presenilin-1: metabolism, Presenilin-2: chemistry, Presenilin-2: genetics, Presenilin-2: metabolism, Protein Domains, Alzheimer’s disease, amyloid precursor protein (APP), amyloid-beta (Aβ), gamma-secretase, intramembrane proteolysis, presenilin, transmembrane domain, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Amyloid Precursor Protein Secretases, Presenilin-1, Presenilin-2

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:36944398; info:eu-repo/semantics/altIdentifier/issn/0021-9258; info:eu-repo/semantics/altIdentifier/issn/1067-8816; info:eu-repo/semantics/altIdentifier/issn/1083-351X; https://pub.dzne.de/record/257784; https://pub.dzne.de/search?p=id:%22DZNE-2023-00499%22

الاتاحة: https://pub.dzne.de/record/257784
https://pub.dzne.de/search?p=id:%22DZNE-2023-00499%22

المؤلفون: Dawkins, Edgar, Derks, Rico J E, Schifferer, Martina, Trambauer, Johannes, Winkler, Edith, Simons, Mikael, Paquet, Dominik, Giera, Martin, Kamp, Frits, Steiner, Harald

المصدر: The journal of biological chemistry 299(4), 103027 (2023). doi:10.1016/j.jbc.2023.103027

مصطلحات موضوعية: info:eu-repo/classification/ddc/540, Humans, Amyloid Precursor Protein Secretases: genetics, Amyloid Precursor Protein Secretases: metabolism, Membrane Lipids: metabolism, Amyloid beta-Peptides: metabolism, Alzheimer Disease: genetics, Alzheimer Disease: metabolism, Cell Line, Amyloid beta-Protein Precursor: metabolism, Presenilin-1: metabolism, Aβ37/38, Alzheimer disease, amyloid precursor protein (APP) processing, amyloid-β peptide (Aβ), erucic acid, lipid homeostasis, lipidomics, membrane thickness, presenilin, γ-secretase, Amyloid Precursor Protein Secretases, Membrane Lipids, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Presenilin-1

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1083-351X; info:eu-repo/semantics/altIdentifier/issn/0021-9258; info:eu-repo/semantics/altIdentifier/issn/1067-8816; info:eu-repo/semantics/altIdentifier/pmid/pmid:36805335; https://pub.dzne.de/record/257785; https://pub.dzne.de/search?p=id:%22DZNE-2023-00500%22

الاتاحة: https://pub.dzne.de/record/257785
https://pub.dzne.de/search?p=id:%22DZNE-2023-00500%22

المؤلفون: Schmidt, Fabian C., Fitz, Katja, Feilen, Lukas P., Okochi, Masayasu, Steiner, Harald, Langosch, Dieter

المساهمون: Deutsche Forschungsgemeinschaft

المصدر: Journal of Biological Chemistry ; volume 299, issue 5, page 104626 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1016/j.jbc.2023.104626
https://api.elsevier.com/content/article/PII:S0021925823002685?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925823002685?httpAccept=text/plain

المؤلفون: Feilen, Lukas P, Chen, Shu-Yu, Fukumori, Akio, Feederle, Regina, Zacharias, Martin, Steiner, Harald

مصطلحات موضوعية: info:eu-repo/classification/ddc

وصف الملف: application/pdf

Relation: https://mediatum.ub.tum.de/1755438; https://mediatum.ub.tum.de/doc/1755438/document.pdf

الاتاحة: https://mediatum.ub.tum.de/1755438
https://mediatum.ub.tum.de/doc/1755438/document.pdf
https://doi.org/10.7554/elife.76090

المؤلفون: Güner, Gökhan, Aßfalg, Marlene, Zhao, Kai, Dreyer, Tobias, Lahiri, Shibojyoti, Lo, Yun, Slivinschi, Bianca Ionela, Imhof, Axel, Jocher, Georg, Strohm, Laura, Behrends, Christian, Langosch, Dieter, Bronger, Holger, Nimsky, Christopher, Bartsch, Jörg W, Riddell, Stanley R, Steiner, Harald, Lichtenthaler, Stefan F

مصطلحات موضوعية: info:eu-repo/classification/ddc, EMBO02, EMBO03, Article, Articles, Alzheimer's disease, ectodomain shedding, glioblastoma, intramembrane proteolysis, TNR12

وصف الملف: application/pdf

Relation: https://mediatum.ub.tum.de/1693411; https://mediatum.ub.tum.de/doc/1693411/document.pdf

الاتاحة: https://mediatum.ub.tum.de/1693411
https://mediatum.ub.tum.de/doc/1693411/document.pdf
https://doi.org/10.15252/emmm.202216084

المؤلفون: Güner, Gökhan, Assfalg, Marlene, Behrends, Christian, Langosch, Dieter, Bronger, Holger, Nimsky, Christopher, Bartsch, Jörg W, Riddell, Stanley R, Steiner, Harald, Lichtenthaler, Stefan, Zhao, Kai, Dreyer, Tobias, Lahiri, Shibojyoti, Lo, Yun, Slivinschi, Bianca, Imhof, Axel, Jocher, Georg, Strohm, Laura

المصدر: EMBO molecular medicine 14(10), e16084 (2022). doi:10.15252/emmm.202216084

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Amyloid Precursor Protein Secretases, Animals, Biomarkers, Cytokine TWEAK, Humans, Ligands, Mice, Receptors, Cell Surface: metabolism, Chimeric Antigen, Tumor Necrosis Factor: metabolism, TWEAK Receptor, Tumor Necrosis Factor-alpha, Alzheimer's disease, TNR12, ectodomain shedding, glioblastoma, intramembrane proteolysis

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1757-4676; info:eu-repo/semantics/altIdentifier/pmid/pmid:36069059; info:eu-repo/semantics/altIdentifier/issn/1757-4684; info:eu-repo/semantics/altIdentifier/issn/1715-4684; https://pub.dzne.de/record/165254; https://pub.dzne.de/search?p=id:%22DZNE-2022-01547%22

الاتاحة: https://pub.dzne.de/record/165254
https://pub.dzne.de/search?p=id:%22DZNE-2022-01547%22

المؤلفون: Feilen, Lukas Peter, Chen, Shu-Yu, Fukumori, Akio, Feederle, Regina, Zacharias, Martin, Steiner, Harald

المصدر: eLife 11, e76090 (2022). doi:10.7554/eLife.76090

مصطلحات موضوعية: info:eu-repo/classification/ddc/600, Alzheimer Disease, Amyloid Precursor Protein Secretases: metabolism, Amyloid beta-Protein Precursor: metabolism, Archaea, Archaeal Proteins, Catalytic Domain, Humans, Lipid Bilayers, Micelles, Presenilin-1: metabolism, Presenilins: chemistry, Presenilins: metabolism, Proteolysis, biochemistry, chemical biology, molecular biophysics, none, structural biology

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:35579427; info:eu-repo/semantics/altIdentifier/issn/2050-084X; https://pub.dzne.de/record/164087; https://pub.dzne.de/search?p=id:%22DZNE-2022-00750%22

الاتاحة: https://pub.dzne.de/record/164087
https://pub.dzne.de/search?p=id:%22DZNE-2022-00750%22

المؤلفون: Assfalg, Marlene, Guener, Goekhan, Mueller, Stephan A., Breimann, Stephan, Langosch, Dieter, Muhle-Goll, Claudia, Frishman, Dmitrij, Steiner, Harald, Lichtenthaler, Stefan F.

المصدر: Faseb Journal

مصطلحات موضوعية: Munich Cluster for Systems Neurology (SyNergy), ddc:610

وصف الملف: application/pdf

Relation: Assfalg, Marlene; Guener, Goekhan; Mueller, Stephan A.; Breimann, Stephan; Langosch, Dieter; Muhle-Goll, Claudia; Frishman, Dmitrij; Steiner, Harald und Lichtenthaler, Stefan F. (2024): Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain. In: Faseb Journal, Bd. 38, Nr. 2, e23442 [PDF, 12MB]; https://epub.ub.uni-muenchen.de/117340/1/The_FASEB_Journal_-_2024_-_Assfalg_-_Cleavage_efficiency_of_the_intramembrane_protease__%E2%80%90secretase_is_reduced_by_the.pdf; http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-117340-2; https://epub.ub.uni-muenchen.de/117340/

الاتاحة: https://epub.ub.uni-muenchen.de/117340/1/The_FASEB_Journal_-_2024_-_Assfalg_-_Cleavage_efficiency_of_the_intramembrane_protease__%E2%80%90secretase_is_reduced_by_the.pdf
https://epub.ub.uni-muenchen.de/117340/
http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-117340-2
https://doi.org/10.1096/fj.202302152R

المؤلفون: Colombo, Alessio Vittorio, Sadler, Rebecca Katie, Llovera, Gemma, Singh, Vikramjeet, Roth, Stefan, Heindl, Steffanie, Sebastian Monasor, Laura, Verhoeven, Aswin, Peters, Finn, Parhizkar, Samira, Kamp, Frits, Gomez de Aguero, Mercedes, Macpherson, Andrew, Winkler, Edith, Herms, Jochen, Benakis, Corinne, Dichgans, Martin, Steiner, Harald, Giera, Martin, Haass, Christian, Tahirovic, Sabina, Liesz, Arthur

المصدر: Colombo, Alessio Vittorio; Sadler, Rebecca Katie; Llovera, Gemma; Singh, Vikramjeet; Roth, Stefan; Heindl, Steffanie; Sebastian Monasor, Laura; Verhoeven, Aswin; Peters, Finn; Parhizkar, Samira; Kamp, Frits; Gomez de Aguero, Mercedes; Macpherson, Andrew; Winkler, Edith; Herms, Jochen; Benakis, Corinne; Dichgans, Martin; Steiner, Harald; Giera, Martin; Haass, Christian; . (2021). Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition. eLife, 10 eLife Sciences Publications 10.7554/eLife.59826

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/159085/

الاتاحة: https://boris.unibe.ch/159085/1/elife-59826.pdf
https://boris.unibe.ch/159085/

المؤلفون: Fluhrer, Regina, Fukumori, Akio, Martin, Lucas, Grammer, Gudula, Haug-Kröper, Martina, Klier, Bärbel, Winkler, Edith, Kremmer, Elisabeth, Condron, Margaret M, Teplow, David B, Steiner, Harald, Haass, Christian

المصدر: Journal of Biological Chemistry. 283(44)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Brain Disorders, Alzheimer's Disease, Acquired Cognitive Impairment, Neurodegenerative, Dementia, Aging, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Aetiology, 2.1 Biological and endogenous factors, Alzheimer Disease, Amino Acid Motifs, Amino Acid Sequence, Amyloid beta-Peptides, Aspartic Acid Endopeptidases, Catalysis, Cell Line, Humans, Models, Biological, Molecular Sequence Data, Mutation, Peptides, Protein Structure, Tertiary, Temperature, Tumor Necrosis Factor-alpha, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2ht7q8wh

المؤلفون: Kaether, Christoph, Lammich, Sven, Edbauer, Dieter, Ertl, Michaela, Rietdorf, Jens, Capell, Anja, Steiner, Harald, Haass, Christian

المصدر: The Journal of Cell Biology, 2002 Aug 01. 158(3), 551-561.

URL الوصول: https://www.jstor.org/stable/1621277

المؤلفون: Edbauer, Dieter, Winkler, Edith, Haass, Christian, Steiner, Harald

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2002 Jun . 99(13), 8666-8671.

URL الوصول: https://www.jstor.org/stable/3059073

المؤلفون: Moehlmann, Tobias, Winkler, Edith, Xia, Xuefeng, Edbauer, Dieter, Murrell, Jill, Capell, Anja, Kaether, Christoph, Zheng, Hui, Ghetti, Bernardino, Haass, Christian, Steiner, Harald

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2002 Jun 01. 99(12), 8025-8030.

URL الوصول: https://www.jstor.org/stable/3058955

المؤلفون: Kulic, Luka, Walter, Jochen, Multhaup, Gerd, Teplow, David B., Baumeister, Ralf, Romig, Helmut, Capell, Anja, Steiner, Harald, Haass, Christian

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2000 May . 97(11), 5913-5918.

URL الوصول: https://www.jstor.org/stable/122556

المؤلفون: Steiner, Andrea, Schlepckow, Kai, Brunner, Bettina, Steiner, Harald, Haass, Christian, Hagn, Franz

مصطلحات موضوعية: info:eu-repo/classification/ddc

وصف الملف: application/pdf

Relation: https://mediatum.ub.tum.de/1585339; https://mediatum.ub.tum.de/doc/1585339/document.pdf

الاتاحة: https://mediatum.ub.tum.de/1585339
https://mediatum.ub.tum.de/doc/1585339/document.pdf
https://doi.org/10.15252/embj.2019104247

المؤلفون: Kong, Li, Dawkins, Edgar, Campbell, Frederick, Winkler, Edith, Derks, Rico J E, Giera, Martin, Kamp, Frits, Steiner, Harald, Kros, Alexander

المصدر: Biochimica et biophysica acta / Biomembranes 1862(5), 183200 (2020). doi:10.1016/j.bbamem.2020.183200

مصطلحات موضوعية: info:eu-repo/classification/ddc/570, Alzheimer Disease, Amyloid Precursor Protein Secretases: metabolism, Cell Membrane: chemistry, Cell Membrane: metabolism, Fatty Acids: chemistry, Fatty Acids, Monounsaturated: chemistry, Humans, Lipid Bilayers: chemistry, Lipid Bilayers: isolation & purification, Membrane Lipids: metabolism, Membrane Proteins: metabolism, Membranes: metabolism, Micelles, Photochemical Processes, Polyethylene Glycols: chemistry

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0006-3002; info:eu-repo/semantics/altIdentifier/issn/0005-2736; info:eu-repo/semantics/altIdentifier/issn/0005-2728; info:eu-repo/semantics/altIdentifier/issn/1879-2642; info:eu-repo/semantics/altIdentifier/pmid/pmid:31972163; https://pub.dzne.de/record/144981; https://pub.dzne.de/search?p=id:%22DZNE-2020-00345%22

الاتاحة: https://pub.dzne.de/record/144981
https://pub.dzne.de/search?p=id:%22DZNE-2020-00345%22

المؤلفون: Trambauer, Johannes, Rodríguez Sarmiento, Rosa María, Fukumori, Akio, Feederle, Regina, Baumann, Karlheinz, Steiner, Harald

المصدر: EMBO reports 21(1), e47996 (2019). doi:10.15252/embr.201947996

مصطلحات موضوعية: info:eu-repo/classification/ddc/570, Humans, Alzheimer Disease: drug therapy, Alzheimer Disease: genetics, Amyloid beta-Peptides: genetics, Amyloid beta-Protein Precursor, Amyloid Precursor Protein Secretases: genetics, Mutation, Presenilin-1: genetics

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:31762188; info:eu-repo/semantics/altIdentifier/issn/1469-3178; info:eu-repo/semantics/altIdentifier/issn/1469-221X; https://pub.dzne.de/record/141641; https://pub.dzne.de/search?p=id:%22DZNE-2020-07965%22

الاتاحة: https://pub.dzne.de/record/141641
https://pub.dzne.de/search?p=id:%22DZNE-2020-07965%22