نتائج البحث - "Steffi Spielberg"

1

Academic Journal

The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system

المؤلفون: Ameera Alsadeq, Henning Fedders, Christian Vokuhl, Nele M. Belau, Martin Zimmermann, Tim Wirbelauer, Steffi Spielberg, Michaela Vossen-Gajcy, Gunnar Cario, Martin Schrappe, Denis M. Schewe

المصدر: Haematologica, Vol 102, Iss 2 (2017)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/7974; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/74848867243f4de08c718a8fb2f36bf5

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2

Academic Journal

The Fungal Quorum-Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

المؤلفون: Ines Leonhardt, Steffi Spielberg, Michael Weber, Daniela Albrecht-Eckardt, Markus Bläss, Ralf Claus, Dagmar Barz, Kirstin Scherlach, Christian Hertweck, Jürgen Löffler, Kerstin Hünniger, Oliver Kurzai

المصدر: mBio, Vol 6, Iss 2 (2015)

مصطلحات موضوعية: Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2150-7511

URL الوصول: https://doaj.org/article/6497b293fb4646f19f117bfd66ba9845

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Supplementary Figure 5 from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0225099541304714728afb14dd03f9
https://doi.org/10.1158/1535-7163.22497400.v1

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4

Supplementary Figure 6 from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a69f26c93f5aec07bb867d44247a68
https://doi.org/10.1158/1535-7163.22497397.v1

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5

Supplementary Figure 2 from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ae69ee45415e884a01153739b3e542
https://doi.org/10.1158/1535-7163.22497412.v1

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6

Supplementary Methods and Figure Legend from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9e81cb83e003dcfff3138727b48a15
https://doi.org/10.1158/1535-7163.22497394

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7

Supplementary Figure 4 from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720aab21e3102992b7778609dfc9fca9
https://doi.org/10.1158/1535-7163.22497403.v1

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8

Supplementary Figure 3 from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e1df71e98d69790ed3b61aa69f3ffd
https://doi.org/10.1158/1535-7163.22497409.v1

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9

Data from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dc49cd1ddfe4c201b351e9fe378699
https://doi.org/10.1158/1535-7163.c.6535603.v1

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10

Supplementary Figure 1 from Breakdown of the FLT3-ITD/STAT5 Axis and Synergistic Apoptosis Induction by the Histone Deacetylase Inhibitor Panobinostat and FLT3-Specific Inhibitors

المؤلفون: Oliver H. Krämer, Frank-Dietmar Böhmer, Thorsten Heinzel, Gesine Bug, Karsten Spiekermann, Harald Polzer, Steffi Spielberg, Marc Buchwald, Hella Anna Bolck, Kristin Pietschmann

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023c2f9a03875ddb015552b9adb086db
https://doi.org/10.1158/1535-7163.22497415

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11

Academic Journal

Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer

المؤلفون: Zulrahman Erlangga, Katharina Wolff, Tanja Poth, Alexander Peltzer, Sven Nahnsen, Steffi Spielberg, Kai Timrott, Norman Woller, Florian Kühnel, Michael P. Manns, Anna Saborowski, Arndt Vogel, Michael Saborowski

المصدر: Cancers; Volume 11; Issue 12; Pages: 1904

مصطلحات موضوعية: organoids, gallbladder, CRISPR/Cas9, Nal-IRI, mouse model

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers11121904

الاتاحة: https://doi.org/10.3390/cancers11121904

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12

Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer

المؤلفون: Tanja Poth, Arndt Vogel, Katharina Wolff, Anna Saborowski, Michael Saborowski, Alexander Peltzer, Norman Woller, Michael P. Manns, Sven Nahnsen, Steffi Spielberg, Kai Timrott, Zulrahman Erlangga, Florian Kühnel

المصدر: Cancers
Volume 11
Issue 12

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb46ae65c46f808b2d9cc588349f3a21
http://europepmc.org/articles/PMC6966678

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13

Genetically flexible murine organoids for mechanistic and functional modeling of cholangiocarcinoma

المؤلفون: D Becker, Zulrahman Erlangga, B. Beer, Michael P. Manns, Lukas E. Dow, Katharina Wolff, Peter Schirmacher, Steffi Spielberg, Jens U. Marquardt, K Unger, Norman Woller, Michael Saborowski, Silke Marhenke, Arndt Vogel, Anna Saborowski

المصدر: 35. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.

مصطلحات موضوعية: Chemistry, Organoid, Computational biology, Functional modeling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::45164db9e5c90408500a140ab5c2d466
https://doi.org/10.1055/s-0038-1677240

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14

Murine liver organoids as a genetically flexible system to study liver cancer in vivo and in vitro

المؤلفون: Björn Hartleben, Michael Saborowski, D Becker, Benedikt Beer, Jens U. Marquardt, Michael P. Manns, Lukas E. Dow, Katharina Wolff, Zulrahman Erlangga, Silke Marhenke, Arndt Vogel, Anna Saborowski, Steffi Spielberg, Norman Woller, Kristian Unger, Peter Schirmacher

المصدر: Hepat. Commun. 3, 423-436 (2019)

مصطلحات موضوعية: Transplantation, Hepatology, Cas9, RNA interference, medicine, Organoid, Cancer research, CRISPR, Context (language use), Biology, Liver cancer, medicine.disease, Phenotype

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9b9989e831d7b8b416b5c310d677fb
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=55656

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15

Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer

المؤلفون: Anna, Saborowski, Katharina, Wolff, Steffi, Spielberg, Benedikt, Beer, Björn, Hartleben, Zulrahman, Erlangga, Diana, Becker, Lukas E, Dow, Silke, Marhenke, Norman, Woller, Kristian, Unger, Peter, Schirmacher, Michael P, Manns, Jens U, Marquardt, Arndt, Vogel, Michael, Saborowski

المصدر: Hepatology Communications

مصطلحات موضوعية: Original Article, Original Articles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0dd3099ef5255faad5055cf1bdde7266
https://pubmed.ncbi.nlm.nih.gov/30859153

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16

The role of ZAP70 kinase in acute lymphoblastic leukemia infiltration into the central nervous system

المؤلفون: Denis M. Schewe, Steffi Spielberg, Ameera Alsadeq, Christian Vokuhl, Tim Wirbelauer, Henning Fedders, Michaela Vossen-Gajcy, Martin Zimmermann, Nele M. Belau, Martin Schrappe, Gunnar Cario

مصطلحات موضوعية: 0301 basic medicine, Receptors, CCR7, Receptors, CCR4, Central nervous system disease, Central Nervous System Neoplasms, 03 medical and health sciences, Promyelocytic leukemia protein, Leukemic Infiltration, hemic and lymphatic diseases, Cell Line, Tumor, medicine, CD135, Animals, Humans, Protein kinase A, Extracellular Signal-Regulated MAP Kinases, Childhood Acute Lymphoblastic Leukemia, ZAP-70 Protein-Tyrosine Kinase, biology, Kinase, Gene Expression Regulation, Leukemic, ZAP70, hemic and immune systems, Hematology, Articles, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Disease Models, Animal, 030104 developmental biology, Gene Knockdown Techniques, Immunology, biology.protein, Heterografts, Female, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552d37333b7d068e51c7b6ad1d05a513
https://europepmc.org/articles/PMC5286942/

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17

In-vivo validation of cancer genes using liver organoids

المؤلفون: Arndt Vogel, Anna Saborowski, Katharina Wolff, B. Beer, Björn Hartleben, M.P. Manns, Norman Woller, Michael Saborowski, Zulrahman Erlangga, Steffi Spielberg

المصدر: Journal of Hepatology. 68:S671

مصطلحات موضوعية: Hepatology, In vivo, Organoid, Cancer research, Cancer gene, Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::03bca9bdad67f7e781981463889eec51
https://doi.org/10.1016/s0168-8278(18)31600-3

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18

The Fungal Quorum-Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

المؤلفون: Markus Bläss, Christian Hertweck, Kirstin Scherlach, Oliver Kurzai, Kerstin Hünniger, Steffi Spielberg, Jürgen Löffler, Ralf A. Claus, Ines Leonhardt, Daniela Albrecht-Eckardt, Michael Weber, Dagmar Barz

المصدر: mBio, Vol 6, Iss 2 (2015)
mBio

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4a49750f37bb1c29e6b5f27f844853
https://doi.org/10.1128/mbio.00143-15

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19

Breakdown of the FLT3-ITD/STAT5 axis and synergistic apoptosis induction by the histone deacetylase inhibitor panobinostat and FLT3-specific inhibitors

المؤلفون: Steffi Spielberg, Frank-Dietmar Böhmer, Karsten Spiekermann, Hella Anna Bolck, Marc Buchwald, Harald Polzer, K Pietschmann, Gesine Bug, Oliver H. Krämer, Thorsten Heinzel

المصدر: Mol. Cancer Ther. 11, 2373-2383 (2012)

مصطلحات موضوعية: Cancer Research, Indoles, medicine.drug_class, Apoptosis, Hydroxamic Acids, Receptor tyrosine kinase, Cell Line, chemistry.chemical_compound, fluids and secretions, hemic and lymphatic diseases, Panobinostat, Gene Duplication, medicine, STAT5 Transcription Factor, Humans, Benzothiazoles, Protein Kinase Inhibitors, biology, Protein Stability, Phenylurea Compounds, Histone deacetylase inhibitor, Myeloid leukemia, hemic and immune systems, Drug Synergism, Staurosporine, Histone Deacetylase Inhibitors, Leukemia, Myeloid, Acute, Oncology, chemistry, fms-Like Tyrosine Kinase 3, Caspases, Gene Knockdown Techniques, embryonic structures, Fms-Like Tyrosine Kinase 3, Proteolysis, Cancer research, biology.protein, Signal transduction, Tyrosine kinase, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dded27a7f64db237ff04f6d706697616
https://pubmed.ncbi.nlm.nih.gov/22942377

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20

Zeta-Chain-Associated Protein Kinase-70 (Zap-70) Promotes Acute Lymphoblastic Leukemia (ALL) Infiltration into the Central Nervous System By Enhancing Chemokine Receptor 7 (CCR7) Expression

المؤلفون: Christian Vokuhl, Martin Schrappe, Ameera Alsadeq, Denis M. Schewe, Henning Fedders, Steffi Spielberg, Gunnar Cario

المصدر: Blood. 126:901-901

مصطلحات موضوعية: Chronic lymphocytic leukemia, Lymphoblast, Immunology, chemical and pharmacologic phenomena, hemic and immune systems, Spleen, C-C chemokine receptor type 7, Cell Biology, Hematology, Biology, medicine.disease, Biochemistry, medicine.anatomical_structure, Downregulation and upregulation, Acute lymphocytic leukemia, Cancer research, medicine, Immunohistochemistry, Bone marrow

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd8b8513ecee202a971d11745679cf10
https://doi.org/10.1182/blood.v126.23.901.901

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