المؤلفون: Rodríguez-Hernández, Diego, Fenwick, Michael K, Zigweid, Rachael, Sankaran, Banumathi, Myler, Peter J, Sunnerhagen, Per, Kaushansky, Alexis, Staker, Bart L, Grøtli, Morten

المصدر: Journal of Medicinal Chemistry. 67(9)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Infectious Diseases, HIV/AIDS, Sexually Transmitted Infections, 5.1 Pharmaceuticals, Good Health and Well Being, Pyrazoles, Plasmodium vivax, Acyltransferases, Structure-Activity Relationship, Antimalarials, Enzyme Inhibitors, Crystallography, X-Ray, Humans, Models, Molecular, Binding Sites, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Pharmacology and pharmaceutical sciences, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/43c8b1r1
https://escholarship.org/content/qt43c8b1r1/qt43c8b1r1.pdf

المؤلفون: Fenwick, Michael K, Reers, Alexandra R, Liu, Yi, Zigweid, Rachael, Sankaran, Banumathi, Shin, Janis, Hulverson, Matthew A, Hammerson, Bradley, Álvaro, Elena Fernández, Myler, Peter J, Kaushansky, Alexis, Van Voorhis, Wesley C, Fan, Erkang, Staker, Bart L

المصدر: ACS Infectious Diseases. 9(10)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Orphan Drug, Biotechnology, Biodefense, Infectious Diseases, Emerging Infectious Diseases, Digestive Diseases, Immunization, Prevention, Vaccine Related, Rare Diseases, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Child, Humans, Cryptosporidiosis, Cryptosporidium, Plasmodium, Drug Development, N-myristoyltransferase, childhood infectious disease, drug discovery, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/43f556fp
https://escholarship.org/content/qt43f556fp/qt43f556fp.pdf

المؤلفون: Xie, Bin, Maker, Allison, Priest, Andrew V, Dranow, David M, Phan, Jenny N, Edwards, Thomas E, Staker, Bart L, Myler, Peter J, Gumbiner, Barry M, Sivasankar, Sanjeevi

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(32)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Cancer, Antibodies, Monoclonal, Cadherins, Cell Adhesion, Crystallography, X-Ray, Humans, Microscopy, Atomic Force, Molecular Dynamics Simulation, Protein Domains, E-cadherin, strand-swap dimer, antibody, 19A11, adhesion, strand–swap dimer

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1mq1h63t
https://escholarship.org/content/qt1mq1h63t/qt1mq1h63t.pdf

المؤلفون: Fenwick, Michael K., Pierce, Phillip G., Abendroth, Jan, Barrett, Kayleigh F., Barrett, Lynn K., Bowatte, Kalinga, Choi, Ryan, Chun, Ian, Conrady, Deborah G., Craig, Justin K., Dranow, David M., Hammerson, Bradley, Higgins, Tate, Lorimer, Donald D., Lukat, Peer, Mayclin, Stephen J., Hewitt, Stephen Nakazawa, Peng, Ying Po, Shanbhogue, Ashwini, Smutney, Hayden, Stigliano, Matthew Z. Z., Tillery, Logan M., Udell, Hannah S., Wallace, Ellen G., DeRocher, Amy E., Phan, Isabelle Q., Staker, Bart L., Subramanian, Sandhya, Van Voorhis, Wesley C., Blankenfeldt, Wulf, Müller, Rolf, Edwards, Thomas E., Myler, Peter J.

المساهمون: U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases, U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences, U.S. Department of Energy, Michigan Economic Development Corporation

المصدر: Communications Biology ; volume 7, issue 1 ; ISSN 2399-3642

الاتاحة: https://doi.org/10.1038/s42003-024-07175-5
https://www.nature.com/articles/s42003-024-07175-5.pdf
https://www.nature.com/articles/s42003-024-07175-5

المؤلفون: Milanes, Jillian E., Yan, Victoria C., Pham, Cong-Dat, Muller, Florian, Kwain, Samuel, Rees, Kerrick C., Dominy, Brian N., Whitehead, Daniel C., Millward, Steven W., Bolejack, Madison, Shek, Roger, Tillery, Logan, Phan, Isabelle Q., Staker, Bart, Moseman, E. Ashley, Zhang, Xiang, Ma, Xipeng, Jebet, Audriy, Yin, Xinmin, Morris, James C.

المساهمون: Nozaki, Tomoyoshi, NIH

المصدر: PLOS Pathogens ; volume 20, issue 8, page e1012412 ; ISSN 1553-7374

الاتاحة: http://dx.doi.org/10.1371/journal.ppat.1012412
https://dx.plos.org/10.1371/journal.ppat.1012412

المؤلفون: Mendez, Alex, Bolling, Cydni, Taylor, Shane, Makumire, Stanley, Staker, Bart, Reers, Alexandra, Hammerson, Brad, Mayclin, Stephen J., Abendroth, Jan, Lorimer, Donald D., Edwards, Thomas E., Tate, Edward W., Subramanian, Sandhya, Bell, Andrew S., Myler, Peter J., Asojo, Oluwatoyin A., Chakafana, Graham

المصدر: Acta Crystallographica: Section F, Structural Biology Communications; Jan2025, Vol. 81 Issue 1, p1-10, 10p

مصطلحات موضوعية: DRUG repositioning, COMMUNICABLE diseases, MALARIA, CLIMATE change, PLASMODIUM, PLASMODIUM vivax

المؤلفون: Rodríguez-Hernández, Diego, Vijayan, Kamalakannan, Zigweid, Rachael, Fenwick, Michael K., Sankaran, Banumathi, Roobsoong, Wanlapa, Sattabongkot, Jetsumon, Glennon, Elizabeth K. K., Myler, Peter J., Sunnerhagen, Per, Staker, Bart L., Kaushansky, Alexis, Grøtli, Morten

المصدر: Nature Communications ; volume 14, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-023-41119-7
https://www.nature.com/articles/s41467-023-41119-7.pdf
https://www.nature.com/articles/s41467-023-41119-7

المؤلفون: Gu, Yushu, Liu, Miaomiao, Staker, Bart L., Buchko, Garry W., Quinn, Ronald J.

المساهمون: National Institute of Allergy and Infectious Diseases, National Health and Medical Research Council, Australian Research Council, Bill and Melinda Gates Foundation, Griffith University

المصدر: ACS Pharmacology & Translational Science ; volume 6, issue 4, page 578-586 ; ISSN 2575-9108 2575-9108

الاتاحة: http://dx.doi.org/10.1021/acsptsci.2c00225
https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00225

المؤلفون: Bolling, Cydni, Mendez, Alex, Taylor, Shane, Makumire, Stanley, Reers, Alexandra, Zigweid, Rachael, Subramanian, Sandhya, Dranow, David M., Staker, Bart, Edwards, Thomas E., Tate, Edward W., Bell, Andrew S., Myler, Peter J., Asojo, Oluwatoyin A., Chakafana, Graham

المصدر: Acta Crystallographica: Section F, Structural Biology Communications; Oct2024, Vol. 80 Issue 10, p269-277, 9p

مصطلحات موضوعية: GLUCOSE-6-phosphate dehydrogenase deficiency, PLASMODIUM vivax, HEMOLYTIC anemia, MALARIA, COMMUNICABLE diseases, GLUCOSE-6-phosphate dehydrogenase

المؤلفون: Helgren, Travis R, Chen, Congling, Wangtrakuldee, Phumvadee, Edwards, Thomas E, Staker, Bart L, Abendroth, Jan, Sankaran, Banumathi, Housley, Nicole A, Myler, Peter J, Audia, Jonathon P, Horn, James R, Hagen, Timothy J

المصدر: Bioorganic & Medicinal Chemistry. 25(3)

مصطلحات موضوعية: Biological Sciences, Medicinal and Biomolecular Chemistry, Chemical Sciences, Infectious Diseases, Emerging Infectious Diseases, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Animals, Anti-Bacterial Agents, Cell Survival, Cells, Cultured, Dose-Response Relationship, Drug, Endothelial Cells, Enzyme Inhibitors, Methionyl Aminopeptidases, Microbial Sensitivity Tests, Molecular Docking Simulation, Molecular Structure, Pulmonary Artery, Rats, Rickettsia prowazekii, Structure-Activity Relationship, Epidemic typhus, Inhibition, Lung endothelial cells, MetAP, Metalloenzyme, Methionine aminopeptidase, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Biochemistry and cell biology, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7nh0n2pb
https://escholarship.org/content/qt7nh0n2pb/qt7nh0n2pb.pdf

المؤلفون: Naqvi, Kubra F, Staker, Bart L, Dobson, Renwick CJ, Serbzhinskiy, Dmitry, Sankaran, Banumathi, Myler, Peter J, Hudson, André O

المصدر: Acta Crystallographica Section F: Structural Biology Communications. 72(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Amino Acid Sequence, Bacterial Proteins, Bartonella henselae, Catalytic Domain, Chromatography, Gel, Cloning, Molecular, Crystallization, Crystallography, X-Ray, Escherichia coli, Gene Expression, Hydro-Lyases, Models, Molecular, Molecular Sequence Data, Protein Conformation, alpha-Helical, Protein Structure, Quaternary, cat-scratch disease, diaminopimelate, dihydrodipicolinate synthase, lysine biosynthesis

URL الوصول: https://escholarship.org/uc/item/847900c3

المؤلفون: Gihaz, Shalev, Gareiss, Peter, Choi, Jae-Yeon, Renard, Isaline, Pal, Anasuya Chattopadhyay, Surovsteva, Yulia, Chiu, Joy E., Thekkiniath, Jose, Plummer, Mark, Hungerford, William, Montgomery, Micaela L., Hosford, Alanah, Adams, Emily M., Lightfoot, Jorge D., Fox, David, Ojo, Kayode K., Staker, Bart L., Fuller, Kevin, Ben Mamoun, Choukri

المصدر: Structure ; volume 30, issue 11, page 1494-1507.e6 ; ISSN 0969-2126

الاتاحة: http://dx.doi.org/10.1016/j.str.2022.09.001
https://api.elsevier.com/content/article/PII:S0969212622003549?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0969212622003549?httpAccept=text/plain

المؤلفون: Andrade Meirelles, Matheus, Almeida, Vitor M., Sullivan, Jaryd R., de Toledo, Ian, dos Reis, Caio Vinicius, Cunha, Micael Rodrigues, Zigweid, Rachel, Shim, Abraham, Sankaran, Banumathi, Woodward, Elijah L., Seibold, Steve, Liu, Lijun, Mian, Mohammad Rasel, Battaile, Kevin P., Riley, Jennifer, Duncan, Christina, Simeons, Frederick R. C., Ferguson, Liam, Joji, Halimatu, Read, Kevin D., Lovell, Scott, Staker, Bart L., Behr, Marcel A., Pilli, Ronaldo A., Couñago, Rafael M.

المصدر: Journal of Medicinal Chemistry; November 2024, Vol. 67 Issue: 21 p19143-19164, 22p

المؤلفون: Andrade Meirelles, Matheus, Almeida, Vitor M., Sullivan, Jaryd R., de Toledo, Ian, dos Reis, Caio Vinicius, Cunha, Micael Rodrigues, Zigweid, Rachel, Shim, Abraham, Sankaran, Banumathi, Woodward, Elijah L., Seibold, Steve, Liu, Lijun, Mian, Mohammad Rasel, Battaile, Kevin P., Riley, Jennifer, Duncan, Christina, Simeons, Frederick R. C., Ferguson, Liam, Joji, Halimatu, Read, Kevin D., Lovell, Scott, Staker, Bart L., Behr, Marcel A., Pilli, Ronaldo A., Couñago, Rafael M.

المساهمون: National Institute of Allergy and Infectious Diseases, Empresa Brasileira de Pesquisa e Inova??o Industrial, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico, Structural Genomics Consortium, Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo, Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 21, page 19143-19164 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.4c01594
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01594

المؤلفون: Heindl, Miriam Ruth, Rupp, Anna-Lena, Schwerdtner, Marie, Bestle, Dorothea, Harbig, Anne, De Rocher, Amy, Schmacke, Luna C., Staker, Bart, Steinmetzer, Torsten, Stein, David A., Moulton, Hong M., Böttcher-Friebertshäuser, Eva

المساهمون: Subbarao, Kanta, Deutsche Forschungsgemeinschaft, State of Hesse LOEWE, HHS | NIH | National Institute of Allergy and Infectious Diseases

المصدر: Journal of Virology ; volume 98, issue 4 ; ISSN 0022-538X 1098-5514

الاتاحة: http://dx.doi.org/10.1128/jvi.00102-24
https://journals.asm.org/doi/pdf/10.1128/jvi.00102-24

المؤلفون: Gilleran, John A., Ashraf, Kutub, Delvillar, Melvin, Eck, Tyler, Fondekar, Raheel, Miller, Edward B., Hutchinson, Ashley, Dong, Aiping, Seitova, Alma, De Souza, Mariana Laureano, Augeri, David, Halabelian, Levon, Siekierka, John, Rotella, David P., Gordon, John, Childers, Wayne E., Grier, Mark C., Staker, Bart L., Roberge, Jacques Y., Bhanot, Purnima

المساهمون: Congressionally Directed Medical Research Programs, National Institutes of Health

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 14, page 12459-12459 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.4c01411
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01411

المؤلفون: Gilleran, John A., Ashraf, Kutub, Delvillar, Melvin, Eck, Tyler, Fondekar, Raheel, Miller, Edward B., Hutchinson, Ashley, Dong, Aiping, Seitova, Alma, De Souza, Mariana Laureano, Augeri, David, Halabelian, Levon, Siekierka, John, Rotella, David P., Gordon, John, Childers, Wayne E., Grier, Mark C., Staker, Bart L., Roberge, Jacques Y., Bhanot, Purnima

المساهمون: Congressionally Directed Medical Research Programs, National Institutes of Health

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 5, page 3467-3503 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.3c01795
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01795

المؤلفون: Phan, Isabelle Q., Subramanian, Sandhya, Kim, David, Murphy, Michael, Pettie, Deleah, Carter, Lauren, Anishchenko, Ivan, Barrett, Lynn K., Craig, Justin, Tillery, Logan, Shek, Roger, Harrington, Whitney E., Koelle, David M., Wald, Anna, Veesler, David, King, Neil, Boonyaratanakornkit, Jim, Isoherranen, Nina, Greninger, Alexander L., Jerome, Keith R., Chu, Helen, Staker, Bart, Stewart, Lance, Myler, Peter J., Van Voorhis, Wesley C.

المساهمون: National Institute of Allergy and Infectious Diseases, Bill and Melinda Gates Foundation, Burroughs Wellcome Fund, National Institutes of Health, National Institute of General Medical Sciences, Pew Charitable Trusts, Fast Grants

المصدر: Scientific Reports ; volume 11, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-021-83730-y
https://www.nature.com/articles/s41598-021-83730-y.pdf
https://www.nature.com/articles/s41598-021-83730-y

المؤلفون: Tillery, Logan, Barrett, Kayleigh, Goldstein, Jenna, Lassner, Jared W., Osterhout, Bram, Tran, Nathan L., Xu, Lily, Young, Ryan M., Craig, Justin, Chun, Ian, Dranow, David M., Abendroth, Jan, Delker, Silvia L., Davies, Douglas R., Mayclin, Stephen J., Calhoun, Brandy, Bolejack, Madison J., Staker, Bart, Subramanian, Sandhya, Phan, Isabelle, Lorimer, Donald D., Myler, Peter J., Edwards, Thomas E., Kyle, Dennis E., Rice, Christopher A., Morris, James C., Leahy, James W., Manetsch, Roman, Barrett, Lynn K., Smith, Craig L., Van Voorhis, Wesley C.

المساهمون: Hofmann, Andreas, National Institute of Allergy and Infectious Diseases, Argonne National Laboratory, Michigan Economic Development Corporation and the Michigan Technology Tri-Corridor, UCB Pharma

المصدر: PLOS ONE ; volume 16, issue 3, page e0241738 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0241738
https://dx.plos.org/10.1371/journal.pone.0241738

المؤلفون: De Paula Sousa, Bruna Katiele, Sigurdardottir, Sunniva, Bourgard, Catarina, V. V. B. Borba, Joyce, Clementino, Leandro, C. Salazar-Alvarez, Luis, Groustra, Sophia, Zigweid, Rachael, Khim, Monique, Staker, Bart, Costa, Fabio Trindade Maranhão, Erikson, Leif A., Sunnerhagen, Per, Horta Andrade, Carolina

Relation: https://doi.org/10.5281/zenodo.10477924; https://doi.org/10.5281/zenodo.10477925; oai:zenodo.org:10477925

الاتاحة: https://doi.org/10.5281/zenodo.10477925