المؤلفون: W. Cameron Black, Abbas Abdoli, Xiuli An, Anick Auger, Patrick Beaulieu, Michel Bernatchez, Cathy Caron, Amandine Chefson, Sheldon Crane, Mohamed Diallo, Stéphane Dorich, Lee D. Fader, Gino B. Ferraro, Sara Fournier, Qi Gao, Yelena Ginzburg, Martine Hamel, Yongshuai Han, Paul Jones, Stéphanie Lanoix, Cyrus M. Lacbay, Marie-Eve Leclaire, Maayan Levy, Yael Mamane, Amina Mulani, Robert Papp, Charles Pellerin, Audrey Picard, Alexander Skeldon, Kathryn Skorey, Rino Stocco, Miguel St.-Onge, Jean-François Truchon, Vouy Linh Truong, Michal Zimmermann, Michael Zinda, Anne Roulston

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Science Policy, Virology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, preclinical evaluation focused, intermittent dosing schedules, excellent adme properties, related kinase mtor, key hydrogen bond, key kinase, synthetic lethal, single agent, pharmacophore model, nct04855656 ), mitigate anemia, erythroid compartment, damage response, attractive target, allow recovery

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_the_Potent_and_Selective_ATR_Inhibitor_Camonsertib_RP-3500_/25126367

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01917.s001
https://figshare.com/articles/journal_contribution/Discovery_of_the_Potent_and_Selective_ATR_Inhibitor_Camonsertib_RP-3500_/25126367

المؤلفون: Monica Bubenik, Pavel Mader, Philippe Mochirian, Fréderic Vallée, Jillian Clark, Jean-François Truchon, Alexander L. Perryman, Victor Pau, Igor Kurinov, Karl E. Zahn, Marie-Eve Leclaire, Robert Papp, Marie-Claude Mathieu, Martine Hamel, Nicole M. Duffy, Claude Godbout, Matias Casas-Selves, Jean-Pierre Falgueyret, Prasamit S. Baruah, Olivier Nicolas, Rino Stocco, Hugo Poirier, Giovanni Martino, Alexanne Bonneau Fortin, Anne Roulston, Amandine Chefson, Stéphane Dorich, Miguel St-Onge, Purvish Patel, Charles Pellerin, Stéphane Ciblat, Thomas Pinter, Francis Barabé, Majida El Bakkouri, Paranjay Parikh, Christian Gervais, Agnel Sfeir, Yael Mamane, Stephen J. Morris, W. Cameron Black, Frank Sicheri, Michel Gallant

المصدر: Journal of Medicinal Chemistry. 65:13198-13215

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::947c93bf7b6803db8ed4beb935e92af5
https://doi.org/10.1021/acs.jmedchem.2c00998

المؤلفون: W. Cameron Black, Michael Zinda, Jordan T.F. Young, Zuomei Li, Yael Mamane, Rino Stocco, Martine Hamel, Artur Veloso, Victoria Rimkunas, Amina Mulani, Kathryn Skorey, Sabrina Vignini-Hammond, Chloe Fugère-Desjardins, William Yang, Hunain Alam, Amandine Chefson, Shou Yun Yin, Marie-Eve Leclaire, Li Li, Sara Fournier, Lee D. Fader, Stéphane Dorich, Valerie Dumais, Émilie Dumas-Bérube, Charles Pellerin, Alexander Skeldon, Robert Papp, Michal Zimmermann, Anne Roulston

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062cfaf9177f49a3206feb599326f494
https://doi.org/10.1158/1535-7163.22896018

المؤلفون: W. Cameron Black, Michael Zinda, Jordan T.F. Young, Zuomei Li, Yael Mamane, Rino Stocco, Martine Hamel, Artur Veloso, Victoria Rimkunas, Amina Mulani, Kathryn Skorey, Sabrina Vignini-Hammond, Chloe Fugère-Desjardins, William Yang, Hunain Alam, Amandine Chefson, Shou Yun Yin, Marie-Eve Leclaire, Li Li, Sara Fournier, Lee D. Fader, Stéphane Dorich, Valerie Dumais, Émilie Dumas-Bérube, Charles Pellerin, Alexander Skeldon, Robert Papp, Michal Zimmermann, Anne Roulston

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a51beae2425d617ba7d0ef61e96c7e6
https://doi.org/10.1158/1535-7163.c.6651330.v1

المؤلفون: Anne Roulston, Michal Zimmermann, Robert Papp, Alexander Skeldon, Charles Pellerin, Émilie Dumas-Bérube, Valerie Dumais, Stéphane Dorich, Lee D. Fader, Sara Fournier, Li Li, Marie-Eve Leclaire, Shou Yun Yin, Amandine Chefson, Hunain Alam, William Yang, Chloe Fugère-Desjardins, Sabrina Vignini-Hammond, Kathryn Skorey, Amina Mulani, Victoria Rimkunas, Artur Veloso, Martine Hamel, Rino Stocco, Yael Mamane, Zuomei Li, Jordan T.F. Young, Michael Zinda, W. Cameron Black

المصدر: Molecular Cancer Therapeutics. 21:245-256

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c5c2c693c809fd51b04d00ce59692a4
https://doi.org/10.1158/1535-7163.mct-21-0615

المؤلفون: Monica, Bubenik, Pavel, Mader, Philippe, Mochirian, Fréderic, Vallée, Jillian, Clark, Jean-François, Truchon, Alexander L, Perryman, Victor, Pau, Igor, Kurinov, Karl E, Zahn, Marie-Eve, Leclaire, Robert, Papp, Marie-Claude, Mathieu, Martine, Hamel, Nicole M, Duffy, Claude, Godbout, Matias, Casas-Selves, Jean-Pierre, Falgueyret, Prasamit S, Baruah, Olivier, Nicolas, Rino, Stocco, Hugo, Poirier, Giovanni, Martino, Alexanne Bonneau, Fortin, Anne, Roulston, Amandine, Chefson, Stéphane, Dorich, Miguel, St-Onge, Purvish, Patel, Charles, Pellerin, Stéphane, Ciblat, Thomas, Pinter, Francis, Barabé, Majida, El Bakkouri, Paranjay, Parikh, Christian, Gervais, Agnel, Sfeir, Yael, Mamane, Stephen J, Morris, W Cameron, Black, Frank, Sicheri, Michel, Gallant

المصدر: Journal of medicinal chemistry. 65(19)

مصطلحات موضوعية: DNA Replication, Ovarian Neoplasms, Mice, Drug Design, Drug Discovery, Animals, Humans, Female, DNA-Directed DNA Polymerase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::531f44b082fb5f00fe6c2f82d97a48bc
https://pubmed.ncbi.nlm.nih.gov/36126059

المؤلفون: Stéphane, Dorich, Jennifer H, Cox, Jason D, Burch, Félix, Chagnon, Bin, Chen, Serge, Léger, Miguel, St-Onge, Lee D, Fader

المصدر: Bioorganicmedicinal chemistry letters. 30(10)

مصطلحات موضوعية: Structure-Activity Relationship, Propanols, Pyridones, Humans, Protein Isoforms, Receptors, Prostaglandin E, EP4 Subtype

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::afd5f8c2f46697580e0728fd72465236
https://pubmed.ncbi.nlm.nih.gov/32201020

المؤلفون: Amit Chattopadhyay, Stéphane Dorich, Vu Linh Ly, Helge Menz, Stephen Hanessian

المصدر: The Journal of Organic Chemistry. 81:2182-2188

مصطلحات موضوعية: Aza Compounds, Molecular Structure, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, Enantioselective synthesis, Stereoisomerism, Cyclopentanes, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, 0104 chemical sciences, 3. Good health, Alkaloids, Polycyclic Compounds, Calyciphylline B

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59118c21ec8fbb50a5b6549fd35aaae
https://doi.org/10.1021/acs.joc.5b02875

المؤلفون: Daniel Tao, Martin Büschleb, Stephen Hanessian, Larry E. Overman, Kyle B. Schenthal, Stéphane Dorich

المصدر: Angewandte Chemie. 128:4226-4258

مصطلحات موضوعية: 010405 organic chemistry, General Medicine, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee987e5bdb4606bc6665ce694abed565
https://doi.org/10.1002/ange.201507549

المؤلفون: Stéphane Dorich, Juan R. Del Valle, Stephen Hanessian

المصدر: Synlett. 25:799-804

مصطلحات موضوعية: Bicyclic molecule, Genus, Stereochemistry, Chemistry, Organic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fc5569045510699399edcf9f3c555393
https://doi.org/10.1055/s-0033-1340794

المؤلفون: Salma Kassem, Amit Chattopadhyay, Stéphane Dorich, Helge Menz, Stephen Hanessian

المصدر: Tetrahedron. 70:439-449

مصطلحات موضوعية: Allylic rearrangement, Stereochemistry, Chemistry, organic chemicals, Organic Chemistry, Drug Discovery, food and beverages, Proline, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5bfff8e3ae83efd9aad78c5a8cbaf1cf
https://doi.org/10.1016/j.tet.2013.11.040

المؤلفون: Stephen Hanessian, Kyle B. Schenthal, Daniel Tao, Larry E. Overman, Stéphane Dorich, Martin Bueschleb

المصدر: ChemInform. 47

مصطلحات موضوعية: Chemistry, Stereochemistry, General Medicine, Natural (archaeology), Quaternary carbon, Stereocenter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f73cc967b3db614d5c3608fcfdbedd8
https://doi.org/10.1002/chin.201619225

المؤلفون: Stephen Hanessian, Stéphane Dorich, Daniel Tao, Kyle B. Schenthal, Martin Büschleb, Larry E. Overman

المصدر: Angewandte Chemie (International ed. in English), vol 55, iss 13
Büschleb, Martin; Dorich, Stéphane; Hanessian, Stephen; Tao, Daniel; Schenthal, Kyle B; & Overman, Larry E. (2016). Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms.. Angewandte Chemie (International ed. in English), 55(13), 4156-4186. doi: 10.1002/anie.201507549. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7rq1s17n

مصطلحات موضوعية: quaternary carbon atoms, Biological Products, 010405 organic chemistry, Chemistry, Stereochemistry, natural products, Organic Chemistry, Total synthesis, chemistry.chemical_element, General Chemistry, 010402 general chemistry, 01 natural sciences, Article, Catalysis, Natural (archaeology), Carbon, 0104 chemical sciences, Stereocenter, Biomimetic synthesis, Chemical Sciences, synthetic methods, Organic chemistry, biomimetic synthesis, Quaternary carbon

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e80be6242b535570e40b9fc61aa304
https://escholarship.org/uc/item/7rq1s17n

المؤلفون: Ramkrishna Reddy Vakiti, Benoît Deschênes-Simard, Stéphane Dorich, Shyamapada Banerjee, Stephen Hanessian

المصدر: The Journal of Organic Chemistry. 77:9458-9472

مصطلحات موضوعية: Threonine, Cyclopentenone, Molecular Structure, Pactamycin, Stereochemistry, Organic Chemistry, Epoxide, Total synthesis, Cyclopentanes, Oxazoline, Cyclopentanone, Salicylates, chemistry.chemical_compound, chemistry, Moiety

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9100a1e2599ac5b6a927c1aefc87c79b
https://doi.org/10.1021/jo301638z

المؤلفون: Udaykumar Soma, Stéphane Dorich, Stephen Hanessian, Benoît Deschênes-Simard

المصدر: Organic Letters. 13:1048-1051

مصطلحات موضوعية: Indolizidines, Natural product, Molecular Structure, Stereochemistry, Organic Chemistry, Indolizines, Molecular Conformation, Absolute configuration, Total synthesis, Stereoisomerism, Indolizidine, Crystallography, X-Ray, Ring (chemistry), Biochemistry, Anti-Bacterial Agents, Ent-cyclizidine, chemistry.chemical_compound, Alkaloids, chemistry, Serine, Side chain, Physical and Theoretical Chemistry, Enantiomer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42921d7eb6083ebbff184fa0b329930
https://doi.org/10.1021/ol103094j

المؤلفون: Stéphane Dorich, Juan R. Del Valle, Stephen Hanessian

المصدر: ChemInform. 45

مصطلحات موضوعية: Chemistry, Organic chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::af12bc92946aa6193e55ef235c8d2b8e
https://doi.org/10.1002/chin.201438112

المؤلفون: Amit Chattopadhyay, Stephen Hanessian, Salma Kassem, Helge Menz, Stéphane Dorich

المصدر: ChemInform. 45

مصطلحات موضوعية: inorganic chemicals, Allylic rearrangement, Benzyl ether, Stereochemistry, Chemistry, organic chemicals, polycyclic compounds, Substrate (chemistry), heterocyclic compounds, General Medicine, urologic and male genital diseases, Decomposition, Pyrrole derivatives

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e38b704c1021788e88d063b14c9c4bbf
https://doi.org/10.1002/chin.201427110

المؤلفون: Amit Chattopadhyay, Stephen Hanessian, Stéphane Dorich, Martin Büschleb

المصدر: The Journal of organic chemistry. 78(17)

مصطلحات موضوعية: Allylic rearrangement, chemistry.chemical_compound, Chemistry, Product (mathematics), Organic Chemistry, Wittig reaction, Organic chemistry, Ether, Ring (chemistry), Quaternary carbon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7563a36411f90dcf5eb5e6c0930599f9
https://pubmed.ncbi.nlm.nih.gov/23915281

المؤلفون: Stephen Hanessian, Helge Menz, Stéphane Dorich

المصدر: Organic letters. 15(16)

مصطلحات موضوعية: chemistry.chemical_classification, Bridged-Ring Compounds, Double bond, Chemistry, Stereochemistry, Organic Chemistry, Stereoisomerism, Allylic alcohol, Biochemistry, Catalysis, Stille reaction, Cyclization, Yield (chemistry), Daphniglaucin C, Core (graph theory), Polycyclic Compounds, Physical and Theoretical Chemistry, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e25205d207103e99b30603af25d0a5b
https://pubmed.ncbi.nlm.nih.gov/23889206

المؤلفون: Ramkrishna Reddy Vakiti, Stéphane Dorich, Christian Lavallée, Amit Chattopadhyay, Stephen Hanessian

المصدر: Bioorganicmedicinal chemistry. 21(7)

مصطلحات موضوعية: medicine.drug_class, Stereochemistry, Clinical Biochemistry, Antibiotics, Plasmodium falciparum, Antiprotozoal Agents, Pharmaceutical Science, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Biochemistry, Functional diversity, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Humans, Malaria, Falciparum, Molecular Biology, Bacteria, 010405 organic chemistry, Chemistry, Pactamycin, Organic Chemistry, Bacterial Infections, 3. Good health, 0104 chemical sciences, Anti-Bacterial Agents, Antiprotozoal, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c99c662b9c369e2a6d8925186584b0
https://pubmed.ncbi.nlm.nih.gov/23434136