المؤلفون: Chin, Stacey E., Schindler, Christina, Vinall, Lisa, Dodd, Roger B., Bamber, Lisa, Legg, Sandrine, Sigurdardottir, Anna, Rees, D. Gareth, Malcolm, Tim I. M., Spratley, Samantha J., Granéli, Cecilia, Sumner, Jonathan, Tigue, Natalie J.

المصدر: Nature Communications ; volume 14, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-023-43484-9
https://www.nature.com/articles/s41467-023-43484-9.pdf
https://www.nature.com/articles/s41467-023-43484-9

المؤلفون: Shamin, Maria, Spratley, Samantha J., Graham, Stephen C., Deane, Janet E.

المساهمون: Wellcome Trust, Royal Society

المصدر: Contact ; volume 4 ; ISSN 2515-2564 2515-2564

الاتاحة: https://doi.org/10.1177/25152564211052382
https://journals.sagepub.com/doi/pdf/10.1177/25152564211052382
https://journals.sagepub.com/doi/full-xml/10.1177/25152564211052382

المؤلفون: Hill, Chris H, Cook, Georgia M, Spratley, Samantha J, Fawke, Stuart, Graham, Stephen C, Deane, Janet E

مصطلحات موضوعية: Cell Line, Ceramides, Galactosylceramidase, Glycosphingolipids, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Protein Binding, Protein Structure, Tertiary, Saposins

وصف الملف: Electronic; application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: https://www.repository.cam.ac.uk/handle/1810/271705

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/271705
https://doi.org/10.17863/CAM.18694

المؤلفون: Hill, Chris H., Cook, Georgia M., Spratley, Samantha J., Fawke, Stuart, Graham, Stephen C., Deane, Janet E.

المصدر: Nature Communications ; volume 9, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-017-02361-y
https://www.nature.com/articles/s41467-017-02361-y.pdf
https://www.nature.com/articles/s41467-017-02361-y

المؤلفون: Spratley, Samantha J, Deane, Janet E

مصطلحات موضوعية: GALC, Krabbe disease, galactocerebroside, lysosomal storage disorder, pharmacological chaperone therapy, β-galactocerebrosidase, Animals, Enzyme Replacement Therapy, Galactosylceramidase, Humans, Leukodystrophy, Globoid Cell, Molecular Chaperones

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/255836

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/255836

المؤلفون: Spratley, Samantha J, Hill, Chris H, Viuff, Agnete H, Edgar, James R, Skjødt, Karsten, Deane, Janet E

مصطلحات موضوعية: Krabbe disease, galactocerebrosidase, globoid cell leukodystrophy, glycosphingolipid, lysosomal storage disease, Cell Line, Galactosylceramidase, Humans, Leukodystrophy, Globoid Cell, Lysosomes, Mutation, Protein Processing, Post-Translational

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/255409

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/255409

المؤلفون: Spratley, Samantha J., Deane, Janet E.

المساهمون: MRC PhD studentship (to S.J.S.), Royal Society University Research Fellowship (to J.E.D.), Wellcome Trust Strategic Award

المصدر: Journal of Neuroscience Research ; volume 94, issue 11, page 1203-1219 ; ISSN 0360-4012 1097-4547

الاتاحة: http://dx.doi.org/10.1002/jnr.23762
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjnr.23762
https://onlinelibrary.wiley.com/doi/pdf/10.1002/jnr.23762
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/jnr.23762

المؤلفون: Hill, Chris H, Viuff, Agnete H, Spratley, Samantha J, Salamone, Stéphane, Christensen, Stig H, Read, Randy J, Moriarty, Nigel W, Jensen, Henrik H, Deane, Janet E

مصطلحات موضوعية: 0601 Biochemistry and Cell Biology, 1101 Medical Biochemistry and Metabolomics, Biomedical, Basic Science, Neurosciences, Stem Cell Research, Rare Diseases, Stem Cell Research - Nonembryonic - Human, Brain Disorders, Orphan Drug, Neurodegenerative, Generic Health Relevance, 2.1 Biological and endogenous factors

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/247951

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/247951

المؤلفون: Hill, Chris H., Viuff, Agnete H., Spratley, Samantha J., Salamone, Stéphane, Christensen, Stig H., Read, Randy J., Moriarty, Nigel W., Jensen, Henrik H., Deane, Janet E.

المساهمون: Wellcome Trust, Royal Society, Lundbeckfonden

المصدر: Chemical Science ; volume 6, issue 5, page 3075-3086 ; ISSN 2041-6520 2041-6539

الاتاحة: http://dx.doi.org/10.1039/c5sc00754b
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC00754B

المؤلفون: Döppler, Heike, Bastea, Ligia I., Borges, Sahra, Spratley, Samantha J., Pearce, Sarah E., Storz, Peter

المساهمون: Parsons, Maddy

المصدر: PLoS ONE ; volume 9, issue 5, page e98090 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0098090
http://dx.plos.org/10.1371/journal.pone.0098090

المؤلفون: Spratley, Samantha J., Bastea, Ligia I., Döppler, Heike, Mizuno, Kensaku, Storz, Peter

المصدر: Journal of Biological Chemistry ; volume 286, issue 39, page 34254-34261 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m111.259424
https://api.elsevier.com/content/article/PII:S0021925820739700?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820739700?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M111.259424

المؤلفون: Hill, Chris H., Viuff, Agnete, Graham, Stephen C., Spratley, Samantha J., Read, Randy J., Jensen, Henrik Helligsø, Deane, Janet E.

المصدر: Hill , C H , Viuff , A , Graham , S C , Spratley , S J , Read , R J , Jensen , H H & Deane , J E 2014 , ' Structural snapshots of GALC: the Krabbe Disease enzyme ' .

الاتاحة: https://pure.au.dk/portal/da/publications/structural-snapshots-of-galc-the-krabbe-disease-enzyme(40ad4b51-56f7-4b28-a0a9-55c7ca14d8f4).html

المؤلفون: Bastea, Ligia I., Döppler, Heike, Pearce, Sarah E., Durand, Nisha, Spratley, Samantha J., Storz, Peter

المصدر: Biochemical Journal ; volume 455, issue 2, page 251-260 ; ISSN 0264-6021 1470-8728

الاتاحة: http://dx.doi.org/10.1042/bj20130281
https://portlandpress.com/biochemj/article-pdf/455/2/251/735676/bj4550251.pdf

المؤلفون: Spratley, Samantha J., Hill, Chris H., Viuff, Agnete H., Edgar, James R., Skjødt, Karsten, Deane, Janet E.

المصدر: Traffic; Aug2016, Vol. 17 Issue 8, p908-922, 15p

مصطلحات موضوعية: GLOBOID cell leukodystrophy, MOLECULAR pathology, GALACTOSYLCERAMIDASE, GENETIC polymorphisms, NEURODEGENERATION, GLYCOSPHINGOLIPIDS, LYSOSOMAL storage diseases

المؤلفون: BASTEA, Ligia I., DÖPPLER, Heike, PEARCE, Sarah E., DURAND, Nisha, SPRATLEY, Samantha J., STORZ, Peter

المصدر: Biochemical Journal; 10/15/2013, Vol. 455 Issue 2, p251-262, 12p

مصطلحات موضوعية: PROTEIN kinases, PHOSPHORYLATION, CELL migration, CELL motility, METASTASIS, PREVENTION