نتائج البحث - "Spilker, Kerri"

1

Academic Journal

Elucidation of the GSK3α Structure Informs the Design of Novel, Paralog-Selective Inhibitors

المصدر: ACS Chemical Neuroscience ; volume 14, issue 6, page 1080-1094 ; ISSN 1948-7193 1948-7193

الاتاحة: http://dx.doi.org/10.1021/acschemneuro.2c00476
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.2c00476

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2

Academic Journal

Gene Targeting Using a Promoterless Gene Trap Vector ("Targeted Trapping") Is an Efficient Method to Mutate a Large Fraction of Genes

المؤلفون: Friedel, Roland H., Plump, Andrew, Lu, Xiaowei, Spilker, Kerri, Jolicoeur, Christine, Wong, Karen, Venkatesh, Tadmiri R., Yaron, Avraham, Hynes, Mary, Chen, Bin, Okada, Ami, McConnell, Susan K., Rayburn, Helen, Tessier-Lavigne, Marc

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2005 Sep . 102(37), 13188-13193.

URL الوصول: https://www.jstor.org/stable/3376538

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3

Academic Journal

Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling

المؤلفون: Krieg, Michael, Stühmer, Jan, Cueva, Juan G, Fetter, Richard, Spilker, Kerri, Cremers, Daniel, Shen, Kang, Dunn, Alexander R, Goodman, Miriam B

المساهمون: National Institute of Neurological Disorders and Stroke, Howard Hughes Medical Institute, H2020 European Research Council

المصدر: eLife ; volume 6 ; ISSN 2050-084X

الاتاحة: http://dx.doi.org/10.7554/elife.20172
https://cdn.elifesciences.org/articles/20172/elife-20172-v3.pdf
https://cdn.elifesciences.org/articles/20172/elife-20172-v3.xml
https://elifesciences.org/articles/20172

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4

Academic Journal

Tau Like Proteins Reduce Torque Generation in Microtubule Bundles

المؤلفون: Krieg, Michael, Stuehmer, Jan, Cueva, Juan G., Fetter, Richard, Spilker, Kerri, Cremers, Daniel, Shen, Kang, Dunn, Alex R., Goodman, Miriam B.

المصدر: Biophysical Journal ; volume 112, issue 3, page 29a-30a ; ISSN 0006-3495

الاتاحة: http://dx.doi.org/10.1016/j.bpj.2016.11.194
https://api.elsevier.com/content/article/PII:S0006349516312243?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006349516312243?httpAccept=text/plain

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5

Academic Journal

Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 20, page 15402-15419 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.1c01458
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01458

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6

Academic Journal

PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons

المؤلفون: Richardson, Claire E, Spilker, Kerri A, Cueva, Juan G, Perrino, John, Goodman, Miriam B, Shen, Kang

المساهمون: Howard Hughes Medical Institute, National Institutes of Health

المصدر: eLife ; volume 3 ; ISSN 2050-084X

الاتاحة: http://dx.doi.org/10.7554/elife.01498
https://cdn.elifesciences.org/articles/01498/elife-01498-v1.pdf
https://cdn.elifesciences.org/articles/01498/elife-01498-v1.xml
https://elifesciences.org/articles/01498

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7

Academic Journal

MTM-6, a Phosphoinositide Phosphatase, is Required to Promote Synapse Formation in Caenorhabditis elegans

المؤلفون: Ericson, Vivian R., Spilker, Kerri A., Tugizova, Madina S., Shen, Kang

المساهمون: Tang, Shao-Jun

المصدر: PLoS ONE ; volume 9, issue 12, page e114501 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0114501
http://dx.plos.org/10.1371/journal.pone.0114501

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8

Academic Journal

Caenorhabditis elegans Muscleblind homolog mbl-1 functions in neurons to regulate synapse formation

المؤلفون: Spilker Kerri A, Wang George J, Tugizova Madina S, Shen Kang

المصدر: Neural Development, Vol 7, Iss 1, p 7 (2012)

مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429

Relation: http://www.neuraldevelopment.com/content/7/1/7; https://doaj.org/toc/1749-8104; https://doaj.org/article/d129904e21e14c68993998fc1702b3b4

الاتاحة: https://doi.org/10.1186/1749-8104-7-7
https://doaj.org/article/d129904e21e14c68993998fc1702b3b4

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9

Academic Journal

Caenorhabditis elegansMuscleblind homolog mbl-1functions in neurons to regulate synapse formation

المؤلفون: Spilker, Kerri A, Wang, George J, Tugizova, Madina S, Shen, Kang

Relation: http://www.neuraldevelopment.com/content/7/1/7

الاتاحة: http://www.neuraldevelopment.com/content/7/1/7

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10

Academic Journal

Human PLD structures enable drug design and characterization of isoenzyme selectivity

المؤلفون: Metrick, Claire M., Peterson, Emily A., Santoro, Joseph C., Enyedy, Istvan J., Murugan, Paramasivam, Chen, TeYu, Michelsen, Klaus, Cullivan, Michael, Spilker, Kerri A., Kumar, P. Rajesh, May-Dracka, Tricia L., Chodaparambil, Jayanth V.

المصدر: Nature Chemical Biology ; volume 16, issue 4, page 391-399 ; ISSN 1552-4450 1552-4469

الاتاحة: http://dx.doi.org/10.1038/s41589-019-0458-4
http://www.nature.com/articles/s41589-019-0458-4.pdf
http://www.nature.com/articles/s41589-019-0458-4

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11

Academic Journal

Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors

المؤلفون: Himmelbauer, Martin K., Xin, Zhili, Jones, J. Howard, Enyedy, Istvan, King, Kristopher, Marcotte, Douglas J., Murugan, Paramasivam, Santoro, Joseph C., Hesson, Thomas, Spilker, Kerri, Johnson, Joshua L., Luzzio, Michael J., Gilfillan, Rab, de Turiso, Felix Gonzalez-Lopez

المصدر: Journal of Medicinal Chemistry ; volume 62, issue 23, page 10740-10756 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.9b01206
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01206

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12

Academic Journal

Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 28, issue 10, page 1964-1971 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2018.03.032
https://api.elsevier.com/content/article/PII:S0960894X1830221X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X1830221X?httpAccept=text/plain

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13

Academic Journal

The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small‐molecule inhibitor.

المؤلفون: Marcotte, Douglas J.¹ (AUTHOR), Spilker, Kerri A.¹ (AUTHOR), Wen, Dingyi¹ (AUTHOR), Hesson, Thomas¹ (AUTHOR), Patterson, Thomas A.¹ (AUTHOR), Kumar, P. Rajesh¹ (AUTHOR), Chodaparambil, Jayanth V.¹ (AUTHOR) jay.chodaparambil@biogen.com

المصدر: Acta Crystallographica: Section F, Structural Biology Communications. Mar2020, Vol. 76 Issue 3, p103-108. 6p.

مصطلحات موضوعية: *NEUROFIBRILLARY tangles, *TAU proteins, *CRYSTAL structure, *CATALYTIC domains, *ALZHEIMER'S disease, *CYTOSKELETAL proteins, *PROTEIN conformation

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14

Author response: Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling

المؤلفون: Krieg, Michael, Stühmer, Jan, Cueva, Juan G, Fetter, Richard, Spilker, Kerri, Cremers, Daniel, Shen, Kang, Dunn, Alexander R, Goodman, Miriam B

الاتاحة: http://dx.doi.org/10.7554/elife.20172.047

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15

Author response: PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons

المؤلفون: Richardson, Claire E, Spilker, Kerri A, Cueva, Juan G, Perrino, John, Goodman, Miriam B, Shen, Kang

الاتاحة: http://dx.doi.org/10.7554/elife.01498.025

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