المؤلفون: Joseph, Sarah B., Abrahams, Melissa-Rose, Moeser, Matthew, Tyers, Lynn, Archin, Nancie M., Council, Olivia D., Sondgeroth, Amy, Spielvogel, Ean, Emery, Ann, Zhou, Shuntai, Doolabh, Deelan, Ismail, Sherazaan D., Karim, Salim Abdool, Margolis, David M., Pond, Sergei Kosakovsky, Garrett, Nigel, Swanstrom, Ronald, Williamson, Carolyn

المساهمون: Moore, Penny L., National Institutes of Health, South African Department of Science and Technology and the National Research Foundation’s Centre of Excellence in HIV Prevention, South African Department of Health and the South African Medical Research Council Special Initiative on HIV Prevention, USAID and CONRAD, South African National Research Foundation, Welcome Trust

المصدر: PLOS Pathogens ; volume 20, issue 2, page e1011974 ; ISSN 1553-7374

الاتاحة: http://dx.doi.org/10.1371/journal.ppat.1011974
https://dx.plos.org/10.1371/journal.ppat.1011974

المؤلفون: Spielvogel, Ean, Lee, Sook-Kyung, Zhou, Shuntai, Lockbaum, Gordon J, Henes, Mina, Sondgeroth, Amy, Kosovrasti, Klajdi, Nalivaika, Ellen A, Ali, Akbar, Yilmaz, Nese Kurt, Schiffer, Celia A, Swanstrom, Ronald

المساهمون: Biochemistry and Molecular Biotechnology, Schiffer Lab

المصدر: eLife ; 12 ; United States ; England

مصطلحات موضوعية: HIV-1, biochemistry, chemical biology, evolution, infectious disease, inhibitor, microbiology, mutations, protease, selection, viruses

Relation: eLife; https://doi.org/10.7554/elife.80328; Spielvogel E, Lee SK, Zhou S, Lockbaum GJ, Henes M, Sondgeroth A, Kosovrasti K, Nalivaika EA, Ali A, Yilmaz NK, Schiffer CA, Swanstrom R. Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance. Elife. 2023 Mar 15;12:e80328. doi:10.7554/eLife.80328. PMID: 36920025; PMCID: PMC10065791.; http://hdl.handle.net/20.500.14038/51932

الاتاحة: https://doi.org/10.7554/eLife.80328
https://hdl.handle.net/20.500.14038/51932

المؤلفون: Lockbaum, Gordon J., Rusere, Linah N., Henes, Mina, Kosovrasti, Klajdi, Rao, Desaboini Nageswara, Spielvogel, Ean, Lee, Sook-Kyung, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar

المساهمون: National Institute of General Medical Sciences, Office of Science, National Institutes of Health, Argonne National Laboratory, U.S. Department of Energy

المصدر: European Journal of Medicinal Chemistry ; volume 257, page 115501 ; ISSN 0223-5234

الاتاحة: http://dx.doi.org/10.1016/j.ejmech.2023.115501
https://api.elsevier.com/content/article/PII:S0223523423004671?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0223523423004671?httpAccept=text/plain

المؤلفون: Bonner, Xavier, Sondgeroth, Amy, McCue, Amelia, Nicely, Nathan, Tripathy, Ashutosh, Spielvogel, Ean, Moeser, Matthew, Ke, Ruian, Leiderman, Karin, Joseph, Sarah B, Swanstrom, Ronald

المصدر: mBio, 15(4)

مصطلحات موضوعية: Humans, Viral Envelope Proteins, Gene Products, env, HIV-1, CD4-Positive T-Lymphocytes, Macrophages, Receptors, CCR5, CD4 Antigens, env Gene Products, Human Immunodeficiency Virus

Relation: https://doi.org/10.17615/hcw5-b115; https://cdr.lib.unc.edu/downloads/3j333c958?file=thumbnail; https://cdr.lib.unc.edu/downloads/3j333c958

الاتاحة: https://doi.org/10.17615/hcw5-b115
https://cdr.lib.unc.edu/downloads/3j333c958?file=thumbnail
https://cdr.lib.unc.edu/downloads/3j333c958

المؤلفون: Clutter, Dana S., Zhou, Shuntai, Varghese, Vici, Rhee, Soo-Yon, Pinsky, Benjamin A., Fessel, W. Jeffrey, Klein, Daniel B., Spielvogel, Ean, Holmes, Susan P., Hurley, Leo B., Silverberg, Michael J., Swanstrom, Ronald, Shafer, Robert W.

المصدر: The Journal of Infectious Diseases, 2017 Aug 01. 216(3), 387-391.

URL الوصول: https://www.jstor.org/stable/26364961

المؤلفون: Zhu, Cheng, Dukhovlinova, Elena, Council, Olivia, Ping, Lihua, Faison, Edgar M., Prabhu, Shamit S., Potter, E. Lake, Upton, Stephen L., Yin, Guowei, Fay, James M., Kincer, Laura P., Spielvogel, Ean, Campbell, Sharon L., Benhabbour, S. Rahima, Ke, Hengming, Swanstrom, Ronald, Dokholyan, Nikolay V.

المصدر: Nature Communications ; volume 10, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-019-08876-w
https://www.nature.com/articles/s41467-019-08876-w.pdf
https://www.nature.com/articles/s41467-019-08876-w

المؤلفون: Spielvogel, Ean, Lee, Sook-Kyung, Zhou, Shuntai, Lockbaum, Gordon J, Henes, Mina, Sondgeroth, Amy, Kosovrasti, Klajdi, Nalivaika, Ellen A, Ali, Akbar, Yilmaz, Nese Kurt, Schiffer, Celia A, Swanstrom, Ronald

الاتاحة: http://dx.doi.org/10.7554/elife.80328.sa2

المؤلفون: Henes, Mina, Lockbaum, Gordon J., Kosovrasti, Klajdi, Leidner, Florian, Nachum, Gily S., Nalivaika, Ellen A., Lee, Sook-Kyung, Spielvogel, Ean, Zhou, Shuntai, Swanstrom, Ronald, Bolon, Daniel N A, Yilmaz, Nese Kurt, Schiffer, Celia A.

المساهمون: Schiffer Lab, Department of Biochemistry and Molecular Pharmacology

المصدر: ACS chemical biology

مصطلحات موضوعية: Biochemistry, Enzymes and Coenzymes, Medicinal Chemistry and Pharmaceutics, Medicinal-Pharmaceutical Chemistry, Molecular Biology, Structural Biology

Relation: Link to Article in PubMed; https://doi.org/10.1021/acschembio.9b00370; ACS Chem Biol. 2019 Aug 13. doi:10.1021/acschembio.9b00370. [Epub ahead of print] Link to article on publisher's site; 1554-8929 (Linking); http://hdl.handle.net/20.500.14038/48889; https://escholarship.umassmed.edu/schiffer/34; schiffer/34

الاتاحة: https://doi.org/10.1021/acschembio.9b00370
https://hdl.handle.net/20.500.14038/48889
https://escholarship.umassmed.edu/schiffer/34

المؤلفون: Rusere, Linah N., Lockbaum, Gordon J., Lee, Sook-Kyung, Henes, Mina, Kosovrasti, Klajdi, Spielvogel, Ean, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar

المساهمون: Schiffer Lab, Department of Biochemistry and Molecular Pharmacology

المصدر: Journal of medicinal chemistry

مصطلحات موضوعية: Biochemistry, Medicinal Chemistry and Pharmaceutics, Medicinal-Pharmaceutical Chemistry, Molecular Biology, Structural Biology

Relation: Link to Article in PubMed; https://doi.org/10.1021/acs.jmedchem.9b00838; J Med Chem. 2019 Aug 6. doi:10.1021/acs.jmedchem.9b00838. [Epub ahead of print] Link to article on publisher's site; 0022-2623 (Linking); http://hdl.handle.net/20.500.14038/48893; https://escholarship.umassmed.edu/schiffer/38; schiffer/38

الاتاحة: https://doi.org/10.1021/acs.jmedchem.9b00838
https://hdl.handle.net/20.500.14038/48893
https://escholarship.umassmed.edu/schiffer/38

المؤلفون: Potempa, Marc, Lee, Sook-Kyung, Yilmaz, Nese Kurt, Nalivaika, Ellen A., Rogers, Amy, Spielvogel, Ean, Carter, Charles W. Jr., Schiffer, Celia A., Swanstrom, Ronald

المساهمون: Schiffer Lab, Department of Biochemistry and Molecular Pharmacology

المصدر: Journal of molecular biology

مصطلحات موضوعية: cleavage site, proline, scissile bond, specificity, substrate recognition, Amino Acids, Peptides, and Proteins, Biochemistry, Enzymes and Coenzymes, Medicinal Chemistry and Pharmaceutics, Medicinal-Pharmaceutical Chemistry, Molecular Biology, Structural Biology, Virology, Viruses

Relation: Link to Article in PubMed; https://doi.org/10.1016/j.jmb.2018.10.022; J Mol Biol. 2018 Nov 7. pii: S0022-2836(18)31000-3. doi:10.1016/j.jmb.2018.10.022. [Epub ahead of print] Link to article on publisher's site; 0022-2836 (Linking); http://hdl.handle.net/20.500.14038/48886; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1030&context=schiffer&unstamped=1; https://escholarship.umassmed.edu/schiffer/31; schiffer/31

الاتاحة: https://doi.org/10.1016/j.jmb.2018.10.022
https://hdl.handle.net/20.500.14038/48886
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1030&context=schiffer&unstamped=1
https://escholarship.umassmed.edu/schiffer/31

المؤلفون: Rusere, Linah, Lockbaum, Gordon J., Henes, Mina, Lee, Sook-Kyung, Spielvogel, Ean, Rao, Desaboini Nageswara, Kosovrasti, Klajdi, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar

المساهمون: Schiffer Lab, Department of Biochemistry and Molecular Pharmacology

المصدر: Journal of medicinal chemistry

مصطلحات موضوعية: HIV-1, protease Inhibitors, structural analysis, Amino Acids, Peptides, and Proteins, Biochemistry, Enzymes and Coenzymes, Medicinal and Pharmaceutical Chemistry, Medicinal Chemistry and Pharmaceutics, Structural Biology, Viruses

Relation: Link to Article in PubMed; https://doi.org/10.1021/acs.jmedchem.0c00529; Rusere LN, Lockbaum GJ, Henes M, Lee SK, Spielvogel E, Rao DN, Kosovrasti K, Nalivaika EA, Swanstrom R, Kurt Yilmaz N, Schiffer CA, Ali A. Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-Tetrahydrofuran in a Pseudo-Symmetric Dipeptide Isostere. J Med Chem. 2020 Jul 16. doi:10.1021/acs.jmedchem.0c00529. Epub ahead of print. PMID: 32672965. Link to article on publisher's site; 0022-2623 (Linking); http://hdl.handle.net/20.500.14038/29501; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2735&context=faculty_pubs&unstamped=1; https://escholarship.umassmed.edu/faculty_pubs/1723; faculty_pubs/1723

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c00529
https://hdl.handle.net/20.500.14038/29501
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2735&context=faculty_pubs&unstamped=1
https://escholarship.umassmed.edu/faculty_pubs/1723

المؤلفون: Swanstrom, Ron, Spielvogel, Ean

Relation: https://doi.org/10.17615/rb7r-tx62; https://cdr.lib.unc.edu/assets/work-ff055336041c3f7d310ad69109eda4a887b16ec501f35afc0a547c4adb97ee72.png

الاتاحة: https://doi.org/10.17615/rb7r-tx62
https://cdr.lib.unc.edu/assets/work-ff055336041c3f7d310ad69109eda4a887b16ec501f35afc0a547c4adb97ee72.png

المؤلفون: Swanstrom, Ron, Spielvogel, Ean

Relation: https://doi.org/10.17615/3697-3v58; https://cdr.lib.unc.edu/assets/work-ff055336041c3f7d310ad69109eda4a887b16ec501f35afc0a547c4adb97ee72.png

الاتاحة: https://doi.org/10.17615/3697-3v58
https://cdr.lib.unc.edu/assets/work-ff055336041c3f7d310ad69109eda4a887b16ec501f35afc0a547c4adb97ee72.png

المؤلفون: Zhou, Shuntai, Hill, Collin S., Spielvogel, Ean, Clark, Michael U., Hudgens, Michael G., Swanstrom, Ronald

المصدر: ACS Infectious Diseases; 12/9/2022, Vol. 8 Issue 12, p2505-2514, 10p

المؤلفون: Rusere, Linah N., Lockbaum, Gordon J., Henes, Mina, Lee, Sook-Kyung, Spielvogel, Ean, Rao, Desaboini Nageswara, Kosovrasti, Klajdi, Nalivaika, Ellen A., Swanstrom, Ronald, Kurt Yilmaz, Nese, Schiffer, Celia A., Ali, Akbar

المصدر: Journal of Medicinal Chemistry; 8/13/2020, Vol. 63 Issue 15, p8296-8313, 18p

المؤلفون: Lee, Sook-Kyung, Zhou, Shuntai, Baldoni, Pedro L., Spielvogel, Ean, Archin, Nancie M., Hudgens, Michael G., Margolis, David M., Swanstrom, Ronald

المصدر: JAIDS - Journal of Acquired Immune Deficiency Syndromes, 74(2)

مصطلحات موضوعية: High-Throughput Nucleotide Sequencing, HIV-1, HIV Infections, Genetic Variation, DNA Primers, Phylogeny, CD4-Positive T-Lymphocytes, Genotype, Anti-Retroviral Agents, Humans

Relation: https://doi.org/10.17615/0339-qq60; https://cdr.lib.unc.edu/downloads/dz010v981?file=thumbnail; https://cdr.lib.unc.edu/downloads/dz010v981

الاتاحة: https://doi.org/10.17615/0339-qq60
https://cdr.lib.unc.edu/downloads/dz010v981?file=thumbnail
https://cdr.lib.unc.edu/downloads/dz010v981

المؤلفون: Henes, Mina, Lockbaum, Gordon J., Kosovrasti, Klajdi, Leidner, Florian, Nachum, Gily S., Nalivaika, Ellen A., Lee, Sook-Kyung, Spielvogel, Ean, Zhou, Shuntai, Swanstrom, Ronald, Bolon, Daniel N.A., Kurt Yilmaz, Nese, Schiffer, Celia A.

المصدر: ACS Chemical Biology; Nov2019, Vol. 14 Issue 11, p2441-2452, 12p

المؤلفون: Rusere, Linah N., Lockbaum, Gordon J., Lee, Sook-Kyung, Henes, Mina, Kosovrasti, Klajdi, Spielvogel, Ean, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar

المصدر: Journal of Medicinal Chemistry; 9/12/2019, Vol. 62 Issue 17, p8062-8079, 18p

المؤلفون: Rusere, Linah N., Lockbaum, Gordon J., Lee, Sook-Kyung, Henes, Mina, Kosovrasti, Klajdi, Spielvogel, Ean, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar

المصدر: Journal of Medicinal Chemistry; 20240101, Issue: Preprints

المؤلفون: Sook-Kyung Lee, Shuntai Zhou, Baldoni, Pedro L., Spielvogel, Ean, Archin, Nancie M., Hudgens, Michael G., Margolis, David M., Swanstrom, Ronald

المصدر: JAIDS: Journal of Acquired Immune Deficiency Syndromes; Feb2017, Vol. 74 Issue 2, p221-228, 8p, 1 Chart, 4 Graphs